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| 1 | Determining the optimal time for bortezomib-based induction chemotherapy followed by autologous hematopoietic stem cell transplant in the treatment of multiple myeloma显示文摘In our study, we determined the efficacy of bortezomib-based induction therapy followed by autologous stem cell transplant (ASCT) in newly diagnosed and relapsed/refractory (R/R) multiple myeloma (MM) patients and compared the advantages of early versus late transplant. We used a retrospective analysis to examine 62 patients, including 46 cases of newly diagnosed MM (early transplant group) and 16 cases of relapsed/refractory MM (late transplant group). All of these patients received bortezomib-based induction therapy followed by ASCT. The efficacy and side effects of the treatment regimen were analyzed. Patients' overall survival (OS) and progression-free survival (PFS) times were determined. The ratio of complete remission to near-complete remission (CR/nCR) was 69.5% versus 56.2% (P=0.361), respectively, for the early transplant group versus the late transplant group, respectively, after receiving bortezomib-based induction therapy; the overall response rates of the two group were 91.3% and 81.2%, respectively (P=0.369). After receiving ASCT, the CR/nCR of the two groups increased to 84.8% and 81.3%, respectively. The median time required for neutrophil engraftment of the early transplant group and the late transplant group was 11 and 14.5 days, respectively (P=0.003); the median time required for platelet engraftment was 13 and 21.5 days (P=0.031), respectively. There were no significant differences in the toxic side effects observed during induction therapy and ASCT between the two groups. The OS of the two groups was not statistically different (P=0.058). The PFS of the early transplant group and the late transplant group was 41.6 and 26.5 months, respectively (P=0.008). Multivariate analysis demonstrated that the time of receiving ASCT, the types of M protein, and the International Staging System (ISS) stage were all independent factors that influenced PFS. In conclusion, patients in a suitable condition for ASCT should be recommended to have an early ASCT immediately after diagnosis. | Junru Liu Juan Li Beihui Huang Dong Zheng Mei Chen Zhenhai Zhou Duorong Xu Waiyi Zou | 2013 | Chinese Journal of Cancer Research2013，25，2： | 4 |
| 2 | Functional identification of three RANK cytoplasmic motif mediating osteoclast differentiation and function 显示文摘 | Wei L Duorong X Hongmei Y | 2004 | J Biol Chem2004，279，54： | 1 |
| 3 | Crystal Growth and Properties of Ca3NbGa3Si2O14 Single Crystals显示文摘 | Wang Zengmei Cheng Xiufeng Yuan Duorong | 2003 | Journal of Crystal Growth2003，249，： | 1 |
| 4 | Crystal Growth and Properties of Ca3NbGa3Si2O14 Single Crystals 显示文摘 | Wang Zengmei Cheng Xiufeng Yuan Duorong | 2003 | Journal of Crystal Growth2003，249，： | 1 |
| 5 | Growth and Characterization of Sr3NbGa3Si2O14 Single Crystals 显示文摘 | Wang Zengmei Yuan Duorong Cheng Xiufeng | 2003 | Journal of Crystal Growth2003，252，： | 1 |
| 6 | Growth and Optical Activity of Ca3 TaGa3Si2 O14 (CTGS) Single Crystal 显示文摘 | Shi Xuzhong Yuan Duorong Wei Aijian | 2006 | Materials Research Bulletin2006，41，： | 1 |
| 7 | Hepatitis B virus infection status is an independent risk factor for multiple myeloma patients after autologous hematopoietic stem cell transplantation显示文摘 | Juan Li Junru Liu Beihui Huang Dong Zheng Mei Chen Zhenhai Zhou Duorong Xu Waiyi Zou | 2013 | Tumor Biology2013，，3： | 1 |
| 8 | The Growth and Properties of Ca3TaGa3Si2O14 Single Crystals 显示文摘 | Wang Zengmei Yuan Duorong Cheng Xiufeng | 2003 | Journal of Crystal Growth2003，253，： | 1 |
| 9 | Growth, Thermal and Optical Properties of Sr3NbGa3Si2O14 Single Crystals 显示文摘 | Wang Zengmei Yuan Duorong Cheng Xiufeng | 2003 | Journal of Crystal Growth2003，258，： | 1 |
| 10 | Synthesis of yttrium aluminum garnet (YAG) by a new sol - gel method 显示文摘 | Sun Zhizhong Yuan Duorong | 2004 | Journal alloy compounds2004，379，： | 1 |
| 11 | Growth and Characterization of Sr3NbGa3Si2O14 Single Crystals显示文摘 | Wang Zengmei Yuan Duorong Cheng Xiufeng | 2003 | Journal of Crystal Growth2003，252，： | 1 |
| 12 | Synthesis of zirconium sols and fibers by electrolysis of zirconium oxychloride显示文摘 | Tao He Xiuling Jiao Dairong Chen Mengkai Lü Duorong Yuan Dong Xu | 2001 | Journal of Non-Crystalline Solids2001，，1： | 1 |
| 13 | Growth of Cadmium Mercury Thiocyanate Dimethyl-Sulphoxide Single Crystal for Laser Frequency Doubling 显示文摘 | Guo Shiyi Yuan Duorong Xu Dong | 2000 | Progress in Crystal Growth and Charact2000，40，： | 1 |
| 14 | The Growth Dynamics and Habits of the CMTD Crystals 显示文摘 | Sun Daliang Guo Shiyi Yuan Duorong | 2000 | Journal of Synthetic Crystals2000，，： | 1 |
| 15 | Growth of Cadmium Mercury Thiocyanate Dimethyl-sulphoxide Single Crystal for Laser Frequency Doubling显示文摘 | Guo Shiyi Yuan Duorong Xu Dong Zhang Guanghui Sun Suoying Meng Fanqing Wang Xinqiang Jiang Xuening Jiang Minhua Sun Daliang Yu Xiling | 2000 | Progress in Crystal Growth and Characterization of Materials2000，，： | 1 |
| 16 | Spectroscopic Properties of Co2+:ZnAl2O4 Nanocrystals in Sol-gel Derived Glass-Ceramics显示文摘 | Duan Xiulan Yuan Duorong Cheng Xiufeng | 2003 | Journal of Physics and Chemistry of Solids2003，64，6： | 1 |
| 17 | A NEW NONLINEAR OPTICAL MATERIAL-ORGANOMETALLIC COMPLEX TRIALLYLTHIOUREA MERCURY CHLORIDE显示文摘Tri-allylthiourea mercury chloride(ATMC),an organometallic complex,is a new nonlinear optical material with high second harmonic generation(SHG)effect.The SHG effect of ATMC is three times as large as that of urea crystal.Transparent single crystal of 15×15×10mm^(3) has been grown.Comprehensive studies of crystal growth,structure,and general properties have been carried out.The results show that organometallic complexes are promising nonlinear optical materials for wide applications. | YUAN Duorong ZHANG Nan TAO Xutang XU Dong JIANG Minhua | 1990 | Chinese Physics Letters1990，7，7： | 1 |
| 18 | Synthesis of yt- trium aluminum garnet (YAG) by a new sol-gel method显示文摘 | Zhizhong Sun Duorong Yuan | 2004 | Journal of alloys and compounds2004，379，： | 1 |
| 19 | Synthesis and characterization of fine lithium niobate powders by sol-gel method显示文摘 | WANG Lihua YUAN Duorong DUAN Xiulan | 2007 | Crystal Research and Technology2007，42，： | 1 |
| 20 | Crystal Growth and Optical Properties of Dy:La3Ga5SiO14 Single Crystals显示文摘 | Wang Zengmei Yuan Duorong | 2004 | Journal of Crystal Growth2004，263，： | 1 |
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