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| 1 | Subclinical atherosclerosis in northern and southern China: the Chinese paradox显示文摘背景冠的心疾病(CHD ) 的发生是更高的在北比在南部的中国,然而,在传统的 CHD 的差别冒险的,解释这。没有学习在可以帮助在发生解释差别的无临床症状的动脉粥样硬化检验了差别。这研究为在北、南部的中国之间的石灰化用冠的计算断层摄影术(CT ) 在无临床症状的动脉粥样硬化检验了这些差别。我们在一个大多中心选择了参加者的一件随机的样品的方法为冠的钙在一个北城市(诺思) 里扫描的进行中的流行病的学习(北京, n = 49 ) 并且在二个南部的城市(南方) 里(上海, n = 50,并且广州, n = 50 ) 。从三个领域中心的参加者(意味着年龄 67 年) 经历了用动脉粥样硬化扫描的多种族的学习为冠的钙测量扫描的冠的风险因素评估和心脏的 CT 协议。结果调整了在诺思中国(北京) 的转变木头的冠的动脉钙 20 是 3.1 +/-0.4 并且在华南(上海和广州) 是 2.2 +/- 0.3 (P = 0.04 ) 。为北京的北城市的吝啬的钙分数比广州的南部的城市的高三倍(P = 0.01 ) 并且比为上海的南部的城市高 2.5 倍(P = 0.03 ) 。结论无临床症状的动脉粥样硬化的程度在广州和上海的二个南部的城市里比那在北京的北城市里是显著地更高的,甚至在为标准心脏的风险因素调整以后。这发现建议标准风险因素充分不在临床的 CHD 发生解释北方南方差别。 | Jie Huang Yang-Feng Wu Xiao-Qing Liu Ding Ding Lian-Cheng Zhao Bin Lu Xian Li Nathan D Wong Laurie D Dustin Stanley P Azen Robert C Detrano | 2011 | Journal of Geriatric Cardiology2011，8，2： | 7 |
| 2 | Effect of age on aortic atherosclerosis显示文摘Objective To examine the association of atherosclerosis burden in the survivors of an asymptomatic elderly cohort study and its relationship to other coronary risk factors (specifically, age) by evaluating aortic atherosclerotic wall burden by magnetic resonance imaging (MRI). Methods A total of 312 participants in an ongoing observational cohort study underwent cardiac and descending thoracic aorta imaging by MRI. Maximum wall thickness was measured and the mean wall thickness calculated.Wall/outer wall ratio was used as a normalized wall index (NWI) adjusted for artery size difference among participants. Percent wall volume (PWV) was calculated as NWI ×100.Results In this asymptomatic cohort (mean age: 76 years), the mean (SD) aortic wall area andwall thicknesswere 222 ±45 mm2 and 2.7 ±0.4 mm, respectively. Maximum wall thickness was 3.4 ±0.6 mm, and PWV was 32% ±4%. Women appeared to have smaller wall area,but after correcting for their smaller artery size, had significantly higher PWV than men (P = 0.03). Older age was associatedwith larger wall area (P = 0.04 for trend) with similar PWVs. However, there were no statistically significant associations between standard risk factors,Framingham global risk, or metabolic syndrome status, therapy for cholesterol or hypertension, coronary or aortic calcium score, and the aortic wall burden. Aortic calcificationwas associated with coronary calcification. Conclusions Asymptomatic elderly in this cohort had a greater descending thoracic aortic wall volume that correlated with age, andwomen had a significantly increased PWV compared to men. In these survivors, the atherosclerotic aortic wall burden was not significantly associated with traditional risk factors or with coronary or aortic calcium scores or coronary calcium progression. Results suggest that age, or as yet unidentified risk factor(s), may be responsible for the increase in atherosclerosis. | Michael A. Chen Miwa Kawakubo Patrick M. Colletti Dongxiang Xu Laurie LaBree Dustin Robert Detrano Stanley P Azen Nathan D. Wong Xue-Qiao Zhao | 2013 | Journal of Geriatric Cardiology2013，10，2： | 6 |
| 3 | 肥大细胞特异性受体介导神经源性炎症和疼痛显示文摘肥大细胞被激活时可释放炎性细胞因子和趋化因子参与天然免疫细胞募集,作为神经系统和免疫系统联系的桥梁,肥大细胞的空间优势使其能够靠近外周神经末梢附近,在感觉神经纤维激活后率先做出反应。该研究发现肥大细胞特异性受体Mrgprb2通过在损伤部位招募天然免疫细胞,参与了炎症性机械痛和热痛觉过敏;肥大细胞可通过神经肽P物质激活Mrgprb2从而释放趋化因子,促使免疫细胞迁移;P物质激活人类肥大细胞上的MRGPRX2(Mrgprb2的同源基因)后也能释放多种促炎细胞因子和趋化因子;P物质介导的炎症反应独立于神经激肽-1受体(NK-1R)。结果表明Mrgprb2/X2参与了神经免疫调节,是治疗炎性痛的潜在靶点。 | Green Dustin P 刘彤彤(译) 唐宗湘(校) | 2020 | 中国疼痛医学杂志2020，26，7： | 2 |
| 4 | Proteome analysis of skeletal muscle from obese and morbidly obese women 显示文摘 | Dustin S Eric P Hoffman | 2005 | Diabetes2005，54，5： | 1 |
| 5 | Neuroinflammation in temporal lobe epilepsy measured using positron emission tomographic imaging of translocator protein显示文摘 | GERSHEN LD ZANOTTI-FREGONARA P DUSTIN IH | 2015 | JAMA Neurol2015，72，8： | 1 |
| 6 | Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication显示文摘 | Dustin T P Kimberly P S Mark F S | 2006 | J Virol2006，80，： | 1 |
| 7 | Are complex decisions better left to the unconscious? Further failed replications of the deliberation- without-attention effect显示文摘 | DUSTIN P CALVILLO ALAN P | 2009 | Judgment and Decision Making2009，，4： | 1 |
| 8 | RNA Mapping:Selection of potent oligonucleotide sequences for antisense experiments 显示文摘 | Siew P H Dustin HO | 2002 | Methods Enymol2002，314，12： | 1 |
| 9 | Classification of human motions using empirical mode decomposition of human micro-Doppler signatures显示文摘 | Dustin P and Narayanyan M | 2013 | IET Radar Sonar & Navigation2013，12，4： | 1 |
| 10 | Chromenes through metal-catalyzed reactions of styrenyl ethers, mechanism and utility in synthesis显示文摘 | Joseph P A Harrity Daniel S La Dustin R Cefalo | 1998 | J Am Chem Soc1998，120，10： | 1 |
| 11 | The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3显示文摘 | SELVARAJ P PLUNKETT M L DUSTIN M | 1987 | Nature1987，326，6111： | 1 |
| 12 | Factor structure and construct validity of the Self-Report psychopathy (SRP) scale and the youth psychopathic traits inventory (YPI) in young men 显示文摘 | Craig SN Dustin P | 2014 | J Pers Disord2014，28，3： | 1 |
| 13 | Vincristine induced tubulin paracryslals in lhe nuclei of mammalian neurons显示文摘 | Dustin P Flament- Durand J Couck A M | 1980 | Submicrosci Cytol1980，12，： | 1 |
| 14 | Chlorine Dioxide Reactionswith Indoor Materials during Building Disinfection:SurfaceUptake显示文摘 | Heidi H Dustin P Richard L | 2009 | Environ Sci Technol2009，43，5： | 1 |
| 15 | Characterization of intercellular adhesion molecule-1ectodomain as an inhibitao lympocyte funtion-associated molecule-1 interaction with ICAM-1 显示文摘 | Meyer D M Dustin M I Garron C P | 1995 | J Immunol1995，155，7： | 1 |
| 16 | The T lymphocyte glycoprotein CD2 binds the cell surface ligand LFA-3显示文摘 | Selvaraj P Plunkett M Dustin M | 1987 | Nature1987，326，6111： | 1 |
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