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| 1 | 通过手术导致的重量损失由胃绕过在疾病的肥胖的病人改进非含酒精的脂肪肝疾病显示文摘 AIM:To evaluate the effects of surgical weight loss(Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients.METHODS:A group of 26 morbidly obese patients aged 45 ± 2 years and with a body mass index > 40 kg/m 2 who underwent open surgical weight loss operations had paired liver biopsies,the first at surgery and the second after 16 ± 3 mo of weight loss.Biopsies were evaluated and compared in a blinded fashion.The presence of metabolic syndrome,anthropometric and biochemical variables were also assessed at baseline and at the time of the second biopsy.RESULTS:Percentage of excess weight loss was 72.1% ± 6.6%.There was a reduction in prevalence of metabolic syndrome from 57.7%(15 patients) to 7.7%(2 patients)(P < 0.001).Any significance difference was observed in aspartate aminotransferase or alanine aminotransferase between pre and postsurgery.There were improvements in steatosis(P < 0.001),lobular(P < 0.001) and portal(P < 0.05) inflammation and fibrosis(P < 0.001) at the second biopsy.There were 25(96.1%) patients with non alcoholic steatohepatitis(NASH) in their index biopsy and only four(15.3%) of the repeat biopsies fulfilled the criteria for NASH.The persistence of fibrosis(F > 1) was present in five patients at second biopsy.Steatosis and fibrosis at surgery were predictors of significant fibrosis postsurgery.CONCLUSION:Restrictive mildly malabsorptive surgery provides significant weight loss,resolution of metabolic syndrome and associated abnormal liver histological features in most obese patients. | Víctor Vargas Helena Allende Albert Lecube Maria Teresa Salcedo Juan A Baena-Fustegueras José M Fort Joaquín Rivero Roser Ferrer Roberto Catalán Eva Pardina Santiago Ramón y Cajal Jaime Guardia Julia Peinado-Onsurbe | 2012 | World Journal of Hepatology2012，4，12： | 6 |
| 2 | Prion-like behavior of MAVS in RIG-I signaling显示文摘 | Eva Marie Y Moresco Diantha La Vine Bruce Beutler | 2011 | Cell Research2011，21，12： | 3 |
| 3 | Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species显示文摘 | Thomas Schmülling Tomá? Werner Michael Riefler Eva Krupková Isabel Bartrina y Manns | 2003 | Journal of Plant Research2003，，3： | 2 |
| 4 | Exercise-associated differences in an array of proteins involved in signal transduction and glucose transport显示文摘 | Mei Y Eva B Alexander V C | 2001 | Appl Physiol2001，90，： | 1 |
| 5 | The EMT signaling pathways in endometrial carcinoma显示文摘 | Eva Colas Nuria Pedrola Laura Devis Tug?e Ertekin Irene Campoy Elena Martínez Marta Llauradó Marina Rigau Mireia Olivan Marta Garcia Silvia Cabrera Antonio Gil-Moreno Jordi Xercavins Josep Castellvi Angel Garcia Santiago Ramon y Cajal Gema Moreno-Bueno Xa | 2012 | Clinical and Translational Oncology2012，，： | 1 |
| 6 | Barrier coatings for type C/SiC ceramic-matrix composites (Review) 显示文摘 | SARKISOV P D POPOVICH N V ORLOVA L A ANAN'EVA Y E | 2008 | Glass and Ceramics2008，65，： | 1 |
| 7 | The product of the ATM Gene is a 370kda Nuclear Phosphoprotein显示文摘 | Gang C Eva Y Lee HP | 1996 | J Biol Chem1996，271，33： | 1 |
| 8 | Thermal Conductivity of Crystalline Chrysotile Asbestos显示文摘 | KUMZEROV A Y PARFEN'EVA L S SMIRNOV I A | 2003 | Physics of the Solid State2003，45，1： | 1 |
| 9 | Dust and Chemical Exposures,andMiscarriage RiskAmongWomenTextile Workers inShanghai,China显示文摘 | Eva Y Wong Roberta M | 2009 | Occup Environ Med2009，66，3： | 1 |
| 10 | Distri- bution of groups I and lI elements between liquidus phases of fluorine-saturated Si-A1-Na-K-Li-HO system显示文摘 | Gramenitskii E N Shchekina T I Alfer' eva Y O | 2008 | Moscow Uni- versity Geology Bulletin2008，63，6： | 1 |
| 11 | Regulation of Arabidopsis tapetum development and function by DYSFUNC- TIONAL TAPETUM1 (DYT1) encoding a putative bHLH transcription factor显示文摘 | Zhang W Sun Y J Timof E]eva L | 2006 | Development2006，133，6： | 1 |
| 12 | Jellyfish and other cnidarian envenomations cause pain by affecting TRPV1 channels显示文摘 | Eva C Angel Y Evert K | 2001 | FEBS Lett2001，580，24： | 1 |
| 13 | Anton marcinci kinetics of dyeing process of blend polypropylene/ polyester fibres with disperse dye 显示文摘 | ANNA U Y EVA B H JANKA 0 K | 2005 | Dyes and Pigments2005，2005，11： | 1 |
| 14 | Oligo(trimethylene carbonate) based supramolecular biomateri als显示文摘 | Patricia Y W Dankers Zheng Zhang Eva Wisse | 2006 | Macromolecules2006，39，25： | 1 |
| 15 | Oligo(trimethylene carbonate)-based supramolecular biomaterials显示文摘 | Patricia Y W Dankers Zheng Zhang Eva Wisse | 2006 | Macromolecules2006，39，25： | 1 |
| 16 | luation Methods Discussion显示文摘 | Liu Y X Jia X Highway Mechanical and Electrical Engineering lity Eva | 2013 | Applied Mechanics and Materials2013，300，： | 1 |
| 17 | Immunological response to Mycobacterium avium subsp, paratuberculosis in chickens显示文摘 | Chui L W King R Eva Y W | 2004 | Can J Vet Res2004，68，4： | 1 |
| 18 | Adaptogenic effect of furostanol glycosides on photosynthetic pigments of tomato leaves under stress显示文摘 | Zinov eva S V Ershov Y V | 2000 | Doklady akademii nauk2000，372，3： | 1 |
| 19 | Physicochemical Reaction In Polymer Composite Materials Made From Carbon, Class, And Basalt Fibers显示文摘 | Kadykova Y A Arlemenko S E Vasill Eva O V | 2003 | Fibre Chemistry2003，35，6： | 1 |
| 20 | Identification of unacceptable background caused by non-specific protein adsorption to the plates using a standardized ELISA显示文摘 | DIERK E R EVA M W SHIN Y K | 1999 | Enzyme-linked Methods1999，226，： | 1 |
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