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| 1 | Strategic management of complex projects:a case study using system dynamics显示文摘 | LYNEIS J M COOPER K G ELS S A | | 0，，03： | 1 |
| 2 | Rapid onset of apoptosis in vitro follows disruption of beta 1 integrin/matrix interactions in human colonic crypt cells显示文摘 | Strater J Wedding U Barth TF Koretz K Elsing C Moller P | 1996 | Gastroenterology1996，100，6： | 1 |
| 3 | Intestinal nematode parasites,cytokines and effector mechanisms显示文摘 | Else K J Finkelman FD | | 0，，08： | 1 |
| 4 | Strategic management of complex projects:A case study using system dynamics显示文摘 | Lyneis J M Cooper K G Els S A | 2001 | System Dynamics Review2001，17，3： | 1 |
| 5 | miR-18, a member of Oncomir-1, targets heat shock transcrip- tion factor 2 in spermatogenesis 显示文摘 | Bj ork J K Sandqvist A Elsing A N | 2010 | Development2010，137，19： | 1 |
| 6 | Have gastrointestinal nematodes outwitted the immune system? 显示文摘 | ELSE K J | 2005 | Parasite Immunology2005，27，1011： | 1 |
| 7 | Low-level infection with Trichuris murissignificantly affects the polarization of the CD4 response显示文摘 | Bancroft A J Else K J Grencis R K | 1994 | Eur J Immunol1994，24，： | 1 |
| 8 | Characterisation of the protec-tive immune response following subcutaneous vaccination ofsusceptible mice against Trichuris muris显示文摘 | Dixon H Little M C Else K J | 2010 | Int J Parasitol2010，40，6： | 1 |
| 9 | Mir -18,a mem- ber of Oncomir -1,targets heat shock transcription factor 2 in sper- matogenesis显示文摘 | BJORK J K SANDQVIST A ELSING A N | 2010 | Development2010，137，19： | 1 |
| 10 | Per- ceived stigma, self-blame, and adjustment among lung, breast and prostate cancer patients显示文摘 | Else Quest N M LoConte N K Schiller J H | 2009 | Psychol Health2009，24，8： | 1 |
| 11 | Mast cells, eosinophils and antibodymediated cellular cytotoxicity are not critical to Trichuris muris显示文摘 | BETTS C J ELSE K J | 1999 | Parasite Immunmol1999，21，1： | 1 |
| 12 | Unresolved issues regarding therole of apoptosis in the pathogenesis of ischemic injury and heartfailure显示文摘 | Els?sser A Suzuki K Schaper J | 2000 | J Mol Cell Cardiol2000，32，5： | 1 |
| 13 | Privatisation and The Quality of Rail Services显示文摘 | P K Else T J James | 1995 | Transportation Research1995，，35： | 1 |
| 14 | Strategic management of complex projects: a case study using system dynamics显示文摘 | Lyneis J M Cooper K G Els S A | 2001 | System Dynamics Review2001，17，3： | 1 |
| 15 | 月桂酰乳酰乳酸钠对感染亚临床产气荚膜梭菌肉鸡生产性能和肠道健康的影响显示文摘产气荚膜梭菌属革兰氏阳性菌,是一种家禽肠道致病菌。由于产气荚膜梭菌亚临床感染常导致肠黏膜损害,降低营养物质的消化,降低生产性能,应采取一种有效的措施控制产气荚膜梭菌的过度生长。为此,本文旨在研究月桂酰乳酰乳酸钠作为一种饲料添加剂防止产气荚膜梭菌在肉鸡肠道内定植(LauL)的药效测定。首先,将月桂酰乳酰乳酸钠与感染产气荚膜梭菌肉鸡的月桂酸单体甘油二脂(MDG)和月桂酸游离脂肪酸(LauL)相比,产气荚膜梭菌损害度16分的结果表明,MDG和LauL两者都有降低损害程度的效果。考虑到体增重和死亡率,LauL比MDG更有效。因此,剂量反应研究目的是确定最佳LauL添加量。试验结果表明,LauL的剂量高于15%,对损害度和死亡率起到预期的积极作用。不添加任何剂量的LauL,生长性能较好。在第3次试验中,将LauL的效果与限制肠道内细菌活性的商业化产品(Aromabiotic波尔60)或限制球虫病的细菌(化学抗球虫药,Clinacox)相比。该产品并没有减少损害的数目和严重程度,且对生产性能无影响。因此,尽管在试验1和试验2中,高于0.15%剂量的LauL产生了显著的作用效果,但是添加月桂酰乳酰乳酸钠并不能降低产气荚膜梭菌在肉鸡体内的定植,故在试验3中并未产生效果。但为进一步研讨月桂酰乳酰乳酸钠作为潜在的添加剂对减少肉鸡产气荚膜梭菌激发的免疫反应的研究,提供了科学依据。 | Lensing M Vander K J D Fabri T Cazemier A Else A J | 2011 | 饲料博览2011，，2： | 0 |
| 16 | Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/-mice显示文摘AIM:To investigate the influence of Trichuris muris(T.muris)infection in a mouse model of genetic susceptibility to inflammatory bowel disease,Mdr1a-/-.METHODS:Mdr1a-/-mice were housed under specific pathogen free conditions to slow the development of colitis and compared to congenic FVB controls.Mice were infected with approximately 200 embryonated ova from T.muris and assessed for worm burden and histological and functional markers of gut inflammation on day 19 post infection.RESULTS:Mdr1a-/-mice exhibited a marked increase in susceptibility to T.muris infection with a 10-fold increase in colonic worm count by day 19 pi compared to FVB controls.Prior to infection,Mdr1a-/-exhibitedlow-level mucosal inflammation with evidence of an enhanced Th1 environment.T.muris infection accelerated the progression of colitis in Mdr1a-/-as evidenced by marked increases in several indicators including histological damage score,mucosal CD4+T-cell and DC infiltration and dramatically increased production of proinflammatory cytokines.CONCLUSION:These data provide further evidence of the complex interaction between T.muris and an inflammatory bowel disease(IBD)-susceptible host which may have relevance to the application of helminth therapy in the treatment of human IBD. | Ekta K Bhardwaj Kathryn J Else Michael T Rogan Geoffrey Warhurst | 2014 | World Journal of Gastroenterology2014，20，7： | 0 |
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