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| 1 | Total hepatectomy and liver transplantation as a two-stage procedure for fulminant hepatic failure: A safe procedure in exceptional circumstances显示文摘AIM: To evaluate the outcomes of two-stage liver transplant at a single institution, between 1993 and March 2015.METHODS: We reviewed our institutional experience with emergency hepatectomy followed by transplantation for fulminant liver failure over a twenty-year period. A retrospective review of a prospectively maintained liver transplant database was undertaken at a national liver transplant centre. Demographic data, clinical presentation, preoperative investigations, cardiocirculatory parameters, operative and postoperative data were recorded.RESULTS: In the study period, six two-stage liver transplants were undertaken. Indications for transplantation included acute paracetamol poisoning(n = 3), fulminant hepatitis A(n = 1), trauma(n = 1) and exertional heat stroke(n = 1). Anhepatic time ranged from 330 to 2640 min. All patients demonstrated systemic inflammatory response syndrome in the first post-operative week and the incidence of sepsis was high at 50%. There was one mortality, secondary to cardiac arrest 12 h following re-perfusion. Two patients required re-transplantation secondary to arterial thrombosis. At a median follow-up of 112 mo, 5 of 6 patients are alive and without evidence of graft dysfunciton.CONCLUSION: Two-stage liver transplantation represents a safe and potentially life-saving treatment for carefully selected exceptional cases of fulminant hepatic failure. | Rebeca Sanabria Mateos Niamh M Hogan Dimitri Dorcaratto Helen Heneghan Venkatesh Udupa Donal Maguire Justin Geoghegan Emir Hoti | 2016 | World Journal of Hepatology2016，8，4： | 3 |
| 2 | Pulmonary Complications After Elective Liver Transplantation—Incidence, Risk Factors, and Outcome显示文摘 | Eric Levesque Emir Hoti Daniel Azoulay Isabelle Honore Bruno Guignard Eric Vibert Philippe Ichai Fadi Antoun Faouzi Saliba Didier Samuel | 2012 | Transplantation Journal2012，，5： | 1 |
| 3 | Caval Inflow to the Graft for Liver Transplantation in Patients With Diffuse Portal Vein Thrombosis: A 12-Year Experience显示文摘 | Prashant Bhangui Chetana Lim Chady Salloum Paola Andreani Mylene Sebbagh Emir Hoti Philippe Ichai Faouzi Saliba Rene Adam Denis Castaing Daniel Azoulay | 2011 | Annals of Surgery2011，，6： | 1 |
| 4 | Thepositive financial impact of using an Intensive CareInformation System in a tertiary Intensive Care Unit 显示文摘 | Eric Levesque Emir Hoti Sofia de La Serna | 2013 | International journal of medical informatics2013，82，3： | 1 |
| 5 | Liver Transplantation: The Current Situation显示文摘 | Rene Adam Emir Hoti | 2009 | Semin Liver Dis2009，，01： | 1 |
| 6 | Liver transplantation for hepatocellular carcinoma: The impact of human immunodeficiency virus infection显示文摘 | Eric Vibert Jean‐Charles Duclos‐Vallée Maria‐Rosa Ghigna Emir Hoti Chady Salloum Catherine Guettier Denis Castaing Didier Samuel René Adam | 2011 | Hepatology2011，，2： | 1 |
| 7 | Liver transplantation for hepatocellular carcinoma in Ireland:Pre-operative alpha-fetoprotein predicts tumour recurrence in a 14-year single-centre national experience显示文摘AIM: To examine the results of orthotopic liver transplantation(OLT) for hepatocellular carcinoma(HCC) in Ireland over a 14-year period.METHODS: Cases of HCC receiving OLT between January 1995 and September 2009 in the Irish Liver Transplant Unit were reviewed from a prospectively maintained database. Outcome measures included overall and recurrence free survival, alpha-fetoprotein(AFP) and tumour pathological features. RESULTS: On explant pathology, 57 patients had HCC. The median follow-up time was 42.7 mo. The overall 1, 3 and 5 years survival was 87.7%, 72.1% and 72.4%. There was no difference in survival when comparedto patients undergoing OLT without malignancy. The tumour recurrence rate was 14%. The Milan criteria were exceeded in 32% of cases but this did not predict overall survival or recurrence. On multivariate analysis pre-operative AFP > 100 ng/m L was an independent risk factor for recurrence(RR = 5.2, CI: 1.1-24.3, P = 0.036).CONCLUSION: Patients undergoing OLT for HCC had excellent survival even when conventional listing criteria were exceeded. Pre-operative AFP predicts recurrence independent of tumour size and its role in selection criteria should be investigated in larger studies. | Donal B O'Connor John P Burke John Hegarty Aiden P McCormick Niamh Nolan Emir Hoti Donal Maguire Justin Geoghegan Oscar Traynor | 2016 | World Journal of Transplantation2016，6，2： | 1 |
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