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| 1 | Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters. | V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun | 2003 | World Journal of Gastroenterology2003，9，10： | 5 |
| 2 | Lactic acid bacteria as pro-technological,bioprotective and health-promoting cultures in the dairy food industry显示文摘Lactic acid bacteria (LAB) constitute pivotal microorganisms for the food industry due to their considerable technological and functional potential.Fermented dairy products,that is ancient traditions worldwide,still have been accepted and consumed today for their nutritional and organoleptic attributes.In accordance with the current trends in the market and greater awareness of consumer well-being,a detailed assessment of the health effects of dairy product consumption has been undertaken with particular reference to the production of bioactive metabolites including i.e.,γ-aminobutyric acid,conjugated linoleic acid,bioactive peptides,exopolysaccharides as well as vitamins during LAB fermentation.The long histories of yogurt,kefir,and traditional fermented milk drink as sources of some certain probiotic bacteria as well as the opportunity to bio-fortify the matrix with bioactive microbial compounds in situ make fermented dairy products an attractive model in the efforts to develop sustainable functional food systems.Therefore,this review provides the main biochemical characteristics and biotechnological application of LAB as pro-technological,bioprotective,and health-promoting in the food chain. | Duygu Ağagündüz Teslime Özge Şahin Şerife Ayten Birsen Yılmaz Bartu Eren Güneşliol Pasquale Russo Giuseppe Spano Fatih Özogul | 2022 | Food Bioscience2022，47，3： | 2 |
| 3 | The superior vena eava syndrome caused by malignant disease,imaging with multi-detector row CT显示文摘 | Eren S Karaman A Okur A | 2006 | Eur J Radiol2006，59，1： | 1 |
| 4 | Enzymatic pre-preatment of cotton, part 1 : desizing and glucose generation in desiz- ing liquor显示文摘 | ANIS P DAVULCU A EREN H A | 2008 | Fibers & Textiles in Eastern Europe2008，16，4： | 1 |
| 5 | Vascular injuries and amputation following limb fractures 显示文摘 | EREN N OZGEN G GUREL A | 1990 | Thorac Cardiovasc Surg1990，38，： | 1 |
| 6 | Production of carotenoids by the isolated yeast of Rhodotorula glutinis显示文摘 | AKSU Z EREN A T | 2007 | Biochemical Engineering Journal2007，35，2： | 1 |
| 7 | Delayed surgical treatmentof supracondylar humerus fractures in children using a me-dial approach显示文摘 | Eren A Güven M Erol B | 2008 | J Child Orthop2008，2，1： | 1 |
| 8 | The distally pedicled peroneal brevis muscle flap: A new flap for the lower leg 显示文摘 | Eren S Ghofrani A Reifonrath M | 2001 | Plast Reconstr Surg2001，107，： | 1 |
| 9 | Does sodium nitroprusside reduce lung injury under cardiopulmonary bypass显示文摘 | Cakir O Oruc A Eren S | 2003 | Eur J Cardiothorac Surg2003，23，6： | 1 |
| 10 | Carotenoids production by the yeastRhodotorula mucilaginosa:Use of agricultural wastes as a carbonsource显示文摘 | Z Aksu A T Eren | 2005 | Process Biochemistry2005，40，9： | 1 |
| 11 | Correlation between posteromedial or postemlateral displacement and cubitus varus deformity in supraeondylar humerus fractures in children显示文摘 | EREN A GUVEN M EROL B | 2008 | J Child Orthop2008，2，2： | 1 |
| 12 | The effect of body mass index on functional parameters and quality of life in COPD patients显示文摘 | SALEPCI B EREN A CAGLAYAN B | 2007 | Tuberk Toraks2007，55，4： | 1 |
| 13 | Evaluation of nutritional risk on admission to the general surgery department显示文摘 | Haldun G Eren E Recep A | 2008 | Bratisl Lek Listy2008，109，2： | 1 |
| 14 | Influencing cocoa flayour using Pichia kluyveriand Kluyveromyces marxianus in a defined mixed starter culture for cocoa fermentation显示文摘 | CRAFACK M MIKKELSEN M S(A)ERENS S | 2013 | International Journal of Food Microbiology2013，167，： | 1 |
| 15 | Afterclearing by ozonation:a novel approach for disperse dyeing of polyester 显示文摘 | Eren H A | 2006 | Coloration Technology2006，122，6： | 1 |
| 16 | Evaluation of nutritional risk on admission to the general surgery department 显示文摘 | Haldun G Eren E Recep A | 2008 | Bratisl Lek Listy2008，109，2： | 1 |
| 17 | Venlafaxine Modulates Depression-Induced Oxidative Stress In Brain And Medulla Of Rat 显示文摘 | EREN I NAZIROGLU M DEMERDAS A | 2007 | Neurochem Res2007，32，3： | 1 |
| 18 | Remote sensing of vegetation health for reclaimed areas of Seyitomer opencast coal mine 显示文摘 | Erener A | 2011 | International Journal of Coal Geology2011，86，1： | 1 |
| 19 | Psychiatric disorders and epige- netics显示文摘 | Eren Kodak E and Ertu~rul A | 2012 | Turk Psikiyatri Derg2012，23，2： | 1 |
| 20 | Simultaneous afterclearing and decolorisation by ozonation after disperse dyeing of polyester显示文摘 | Eren H A | 2007 | Coloration Technology2007，123，4： | 1 |
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