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| 1 | A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis显示文摘AIM: To assess the effect of our novel cell-permeable nuclear factor-kappaB (NF-κB) inhibitor peptide PN50 in an experimental model of acute pancreatitis. PN50 was produced by conjugating the cell-penetrating penetratin peptide with the nuclear localization signal of the NF-κB p50 subunit.METHODS: Pancreatitis was induced in male Wistar rats by administering 2×100 μg/kg body weight of cholecystokininoctapeptide (CCK) intraperitoneally (IP) at an interval of 1 h. PN50-treated animals received 1 mg/kg of PN50 IP 30 min before or after the CCK injections. The animals were sacrificed 4 h after the first injection of CCK.RESULTS: All the examined laboratory (the pancreatic weight/body weight ratio, serum amylase activity,pancreatic levels of TNF-α and IL-6, degree of lipid peroxidation, reduced glutathione levels, NF-κB binding activity, pancreatic and lung myeloperoxidase activity) and morphological parameters of the disease were improved before and after treatment with the PN50 peptide.According to the histological findings, PN50 protected the animals against acute pancreatitis by favoring the induction of apoptotic, as opposed to necrotic acinar cell death associated with severe acute pancreatitis.CONCLUSION: Our study implies that reversible inhibitors of stress-responsive transcription factors like NF-κB might be clinically useful for the suppression of the severity of acute pancreatitis. | Tamás Letoha Csaba Somlai Tamáas Takács Annamária Szabolcs Katalin Jármay Zoltán Rakonczay Jr Péter Hegyi Ilona Varga József Kaszaki István Krizbai Imre Boros Ern(?) Duda Erzsébet Kusz Botond Penke | 2005 | World Journal of Gastroenterology2005，11，7： | 15 |
| 2 | Investigation of IrO 2 /Ta 2 O 5 thin film evolution显示文摘 | János Kristóf Tamás Szilágyi Erzsébet Horváth Achille De Battisti Ray L. Frost ákos Rédey | 2003 | Thermochimica Acta2003，，1： | 1 |
| 3 | The autophagic defect in Niemann-Pick disease type C neurons differs from somatic cells and reduces neuronal viability显示文摘 | Meske V Erz J Priesnitz T | 2014 | J Neurobiol Dis2014，64，： | 1 |
| 4 | A link between a hemostatic disorder and preterm PROM:a role for tissue factor and tissue factor pathway inhibitor显示文摘 | Erze O Espinoza J Chatworapongsa T | 2008 | J Matern Fetal Neonatal Med2008，21，： | 1 |
| 5 | Mechano-chemical intercalation of low reactivity kaolinite显示文摘 | l~va Mak6 J~inos Krist6f Erzs~bet Horvdth | 2013 | Ap- plied Clay Science2013，，8384： | 1 |
| 6 | Acute Kidney Injury Is Associated With Higher Morbidity and Resource Utilization in Pediatric Patients Undergoing Heart Surgery显示文摘 | Roland Tóth Tamás Breuer Zsuzsanna Cserép Dániel Lex Levente Fazekas Erzsébet Sápi András Szatmári János Gál Andrea Székely | 2012 | The Annals of Thoracic Surgery2012，，6： | 1 |
| 7 | Automatic Real - time Quality Con- trol of Surface Synoptic Observations显示文摘 | Wolfson N Erze J Alperson Z | 1978 | Journal of applied meteor- ology1978，，17： | 1 |
| 8 | Doubled Haploid Production Using an Improved Anther Culture Protocol for Sorghum[Sorghum bicolor(L.)Moench]显示文摘Sorghum[Sorghum bicolor(L.)Moench]can benefit from accelerated breeding and release of improved varieties through doubled haploid technology.The technology has been used in speeding up the breeding of other major cereals such as wheat,maize and rice,for which generally widely applied optimised protocols exist.A reproducible protocol for the crop,that can overcome genotype dependency and other species-specific challenges such as phenolic exudation is however lacking.This study aimed at sorghum doubled haploids production thereby contributing to the development of an improved protocol.From the 28 hybrid genotypes,both F1 registered-and experimental hybrids involved,this study successfully produced haploids from five genotypes and subsequently,four confirmed doubled-haploid lines on W14mf medium or its modification with 1.0 gl^(-1)L-proline,1.0 gl^(-1)L-asparagine and 1.0 gl^(-1)KH_(2)PO_(4).Medium 190-2Cu was used for regeneration and rooting,which occurred successfully,if the calli were transferred on to it less than 7 days after induction,and temperature was maintained at 25°C under light condition.Genotype dependency was not wholly overcome;however,sorghum’s high tillering ability and abiotic stress tolerance were observed to contribute to attainment of haploid plantlets.Spontaneous diploids producing seeds at rates of upto 80.5%were obtained,therefore eliminating the need for colchicine duplication. | Paul Chege Erzsébet Kiss Csaba Lantos Andrea Palágyi János Pauk | 2021 | Phyton-International Journal of Experimental Botany2021，90，2： | 1 |
| 9 | Kaolinite–urea complexes obtained by mechanochemical and aqueous suspension techniques—A comparative study显示文摘 | éva Makó János Kristóf Erzsébet Horváth Veronika Vágv?lgyi | 2008 | Journal of Colloid And Interface Science2008，，2： | 1 |
| 10 | Investigation of IrO2/Ta2O5 thin film evolution显示文摘 | KRISTOF János SZILAGYI Tamás HORVAHT Erzsébet etc | 2004 | Thermochemical Actal2004，413，： | 1 |
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