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| 1 | Photodegradation paths of cefotaxime显示文摘 | Lerner D A Bonnefond G Fabre H | 1988 | J Pharm Sci1988，77，8： | 1 |
| 2 | Are hepatomas a good target for suicide gene therapy ? An experimental study in rat using retroviral-mediated transfer of thymidine kinase gene 显示文摘 | Nagy H Panis Y Fabre M | 1998 | Surgery1998，123，1： | 1 |
| 3 | Alkaloids from Galipea officinalis显示文摘 | Rakotoson J H Fabre N Jacquemond-Collet I | 1998 | Planta Med1998，64，8： | 1 |
| 4 | Detection of cephalosporins and decomposition products by liquid chromatography with indirect electrochemical detection 显示文摘 | Kok W T | 1988 | Anal Chem1988，60，： | 1 |
| 5 | Minimum detectable level evaluation of inverse beamforming using Outpost SUNRISE data显示文摘 | J Paquin Fabre James H Wilson | 1995 | J Acoust Soc Am1995，98，6： | 1 |
| 6 | Retinitis pigmentosa:rod photoreceptor rescue by a calciumchannel blocker in the rd mouse 显示文摘 | Frasson M Sahel JA Fabre M Simonutti M Dreyfus H Picaud S | 1999 | Nat Med1999，5，10： | 1 |
| 7 | Acute generalized exanthematous pustulosis due to fluconazole 显示文摘 | Fabre B Albes B Belhadjali H | 2002 | Ann Dermatol Venereol2002，129，3： | 1 |
| 8 | Robustness testing for a capillary electrophoresis method using the “short-end injection” technique显示文摘 | FABRE H MESPLET N | 2000 | J Chromatogr A2000，897，1： | 1 |
| 9 | Minimum detectable level evaluation of inverse beamforming using outpost sunrise data显示文摘 | J P FABRE J H WILSON | 1995 | JASA1995，98，： | 1 |
| 10 | Efficient suicide gene therapy of transduced and distant untransduced ovary tumors is correlated with significant increase of intratumoral T and NK cells显示文摘 | NAGY H J PANIS Y FABRE M | 2000 | Biomed Pharmacother2000，54，10： | 1 |
| 11 | Lipoproteins sex hormones and inflammatory markers in association with prostate cancer显示文摘 | Grosman H Fabre B Mesch V | 2010 | Aging Male2010，13，2： | 1 |
| 12 | A second generation current-controlled conveyor with negative intrinsic resistance显示文摘 | Barthelemy H Fabre A | 2002 | IEEE Trans Cite and Syst -Ⅰ: Funda Theo and Appl2002，49，1： | 1 |
| 13 | Lipoproteins, sex hormones and inflammatory markers in association with prostate cancer 显示文摘 | Grosman H Fabre B Mesch V | 2010 | Aging Male2010，13，2： | 1 |
| 14 | Photoisomerization kinetics of cefuroxime axetil and related compounds显示文摘 | Fabre H Ibork H Lerner D A | 1994 | J Pharm Sci1994，83，4： | 1 |
| 15 | Protein measurement with Folin phenol reagent显示文摘 | LOWRY O H ROSEBROUGH N J FABR A L | 1951 | J Biol Chem1951，193，： | 1 |
| 16 | Galectin-9 and IL-21 mediate cross-regulation between Th17 and Treg cells during acute hepatitis C显示文摘 | Kared H Fabre T Bédard N | | 0，，： | 1 |
| 17 | Current-mode bandpass filters with Q-magnification 显示文摘 | Amrami H | 1996 | IEEE Trans Circ SystⅡ1996，43，12： | 1 |
| 18 | Sucide gene therapy of ovrian cancer:an experimental study in rats using retroviral-mediated transfer of simplex virus thymidine kinase gene显示文摘 | Nagy H J Panis Y Fabre M | 2000 | Anticancer Res2000，20，6： | 1 |
| 19 | Prenatal and postnatal ciliated hepatic foregut cysts in infants显示文摘 | Florent Guérin Rim Hadhri Monique Fabre Danièle Pariente Virginie Fouquet Hélène Martelli Frédéric Gauthier Sophie Branchereau | 2010 | Journal of Pediatric Surgery2010，，3： | 1 |
| 20 | ID7 Isolated from Bauhinia variegata Stem Inhibits Tumor Progression and Metastatic Mechanisms of Triple Negative Breast Cancer in Vivo显示文摘Background:The breast cancer has been the most common form of cancer among women.The triple negative subtype represents 20%of all breast cancer cases in the world and is standing out by affecting young women and being aggressive.The main cause of death of patients with cancer is due to metastasis,which can reach the liver and lungs.Objective:The activities of ID7 fraction of the stems of Bauhinia variegata L.on breast cancer,lung metastasis and liver inflammatory process were evaluated.Method:ID7 was characterized by mass-spectrometry.The viability of murine mammary cells(4T1)treated with ID7 was assessed by MTT,trypan blue and fluorescence assay and viability of BT-20,MDA-MB-231 and MCF-7 human breast cancer tumor lines by MTS.The cell migration,invasion using matrigel and adhesion were performed.The expression of cell death proteins was quanitified by western blot and the gelatinases by zimogram.The ID7 activity of the tumor(4T1)and metastatic progession in vivo was evaluated.Results:ID7 reduced the 4T1 and MDA-MB-231viability and increased the late apoptosis,inhibited the 4T1 migration and invasion,increased the 4T1 adhesion and decreased the secreted active gelatinases.ID7 also increased the expression of PARP,caspase-7 and caspase-8,RIP and TNF-R1.In vivo,the ID7 decreased the volume and weight of the tumors and decreased lung metastasis and inflammation in the liver.The characterization showed mainly the presence of oleic acid,myricetin,quercetin and kaempferol in ID7.Conclusion:Thus,it was found that ID7 fraction exhibits selective antitumor and on the mechanisms of breast cancer metastasis activity,preventing lung metastasis and inflammation in the liver.It is suggested that fatty acids and flavonoids are correlated with such activities. | Kamilla Monteiro dos Santos Izabela Natalia Faria Gomes Renato JoséSilva Oliveira Fernanda E.Pinto Bruno Oliveira Fabrício P.Batista Rafael Cesar Russo Chagas Hélio B.Santos Ralph G.Thomé Wanderson Romao Rui Manuel Reis Maria Luiza Vilela Oliva Rosy Iara Maciel de Azambuja Ribeiro | 2019 | Journal of Pharmacy and Pharmacology2019，7，7： | 1 |
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