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| 1 | Single vs dual(en bloc) kidney transplants from donors ≤ 5 years of age: A single center experience显示文摘AIM: To compare outcomes between single and dual en bloc(EB) kidney transplants(KT) from small pediatric donors. METHODS: Monocentric nonprospective review of KTs from pediatric donors ≤ 5 years of age. Dual EB KT was defined as keeping both donor kidneys attached tothe inferior vena cava and aorta, which were then used as venous and arterial conduits for the subsequent transplant into a single recipient. Donor age was less useful than either donor weight or kidney size in decision-making for kidney utilization as kidneys from donors < 8 kg or kidneys < 6 cm in length were not transplanted. Post-transplant management strategies were standardized in all patients.RESULTS: From 2002-2015, 59 KTs were performed including 34 dual EB and 25 single KTs. Mean age of donors(17 mo vs 38 mo, P < 0.001), mean weight(11.0 kg vs 17.4 kg, P = 0.046) and male donors(50% vs 84%, P = 0.01) were lower in the dual EB compared to the single KT group, respectively. Mean cold ischemia time(21 h), kidney donor profile index(KDPI; 73% vs 62%) and levels of serum creatinine(SCr, 0.37 mg/d L vs 0.49 mg/d L, all P = NS) were comparable in the dual EB and single KT groups, respectively. Actuarial graft and patient survival rates at 5-years follow-up were comparable. There was one case of thrombosis resulting in graft loss in each group. Delayed graft function incidence(12% dual EB vs 20% single KT, P = NS) was slightly lower in dual EB KT recipients. Initial duration of hospital stay(mean 5.4 d vs 5.6 d) and the one-year incidences of acute rejection(6% vs 16%), operative complications(3% vs 4%), and major infection were comparable in the dual EB and single KT groups, respectively(all P = NS). Mean 12 mo SCr and abbreviated MDRD levels were 1.17 mg/d L vs 1.35 mg/d L and 72.5 m L/min per 1.73 m^2 vs 60.5 m L/min per 1.73 m^2(both P = NS) in the dual EB and single KT groups, respectively. CONCLUSION: By transplanting kidneys from young pediatric donors into adult recipients, one can effectively expand the limited donor pool and achieve excellent medium-term outcomes. | Yousef Al-Shraideh Umar Farooq Hany El-Hennawy Alan C Farney Amudha Palanisamy Jeffrey Rogers Giuseppe Orlando Muhammad Khan Amber Reeves-Daniel William Doares Scott Kaczmorski Michael D Gautreaux Samy S Iskandar Gloria Hairston Elizabeth Brim Margaret Mangus Robert J Stratta | 2016 | World Journal of Transplantation2016，6，1： | 3 |
| 2 | Liver bioengineering:Current status and future perspectives显示文摘The present review aims to illustrate the strategies that are being implemented to regenerate or bioengineer livers for clinical purposes.There are two general pathways to liver bioengineering and regeneration.The first consists of creating a supporting scaffold,either synthetically or by decellularization of human or animal organs,and seeding cells on the scaffold,where they will mature either in bioreactors or in vivo.This strategy seems to offer the quickest route to clinical translation,as demonstrated by the development of liver organoids from rodent livers which were repopulated with organ specific cells of animal and/or human origin.Liver bioengineering has potential for transplantation and for toxicity testing during preclinical drug development.The second possibility is to induce liver regeneration of dead or resected tissue by manipulating cell pathways.In fact,it is well known that the liver has peculiar regenerative potential which allows hepatocyte hyperplasia after amputation of liver volume.Infusion of autologous bone marrow cells,which aids in liver regeneration,into patients was shown to be safe and to improve their clinical condition,but the specific cells responsible for liver regeneration have not yet been determined and the underlying mechanisms remain largely unknown.A complete understanding of the cell pathways and dynamics and of the functioning of liver stem cell niche is necessary for the clinical translation of regenerative medicine strategies.As well,it will be crucial to elucidate the mechanisms through which cells interact with the extracellular matrix,and how this latter supports and drives cell fate. | Christopher Booth Tom Soker Pedro Baptista Christina L Ross Shay Soker Umar Farooq Robert J Stratta Giuseppe Orlando | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 3 | Preparation of some new tugsten carbide hardmetals显示文摘 | Farooq T Davies T J | 1990 | Powder Metallurgy Intermational1990，22，4： | 1 |
| 4 | Analysis of the Petri net model of parallel manufacturing processes with shared resources显示文摘 | Farooq A Huang H J Wang X L | 2011 | In for marion Sciences2011，181，7： | 1 |
| 5 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 6 | Cardiac dysfunction after left permanent cerebral focal ischemia:the brain and heart connection显示文摘 | Min J Farooq MU Greenberg E | 2009 | Stroke2009，40，7： | 1 |
| 7 | Biosorption of heavy metal ions using wheat ba~ed biosorbents--a review of the recent literature显示文摘 | Farooq U Kozinski J A Khan M A | 2010 | Bioresource Technology2010，101，： | 1 |
| 8 | Biosorption of heavy metal ions using wheat based biosorbents-A review of the recent literature显示文摘 | Farooq U Kozinski J A Khan M A | 2010 | Bioresource Technology2010，101，14： | 1 |
| 9 | Optimal Trajectory Regulation for Radar Imaging Guidanee显示文摘 | Farooq A Limebeer D J N | 2008 | Journal of Guidance Control and Dynamics2008，31，4： | 1 |
| 10 | Microwave roasting effects on the physico -chemical composition and oxida- tive stability of sunflower seed oil 显示文摘 | Fozia A Farooq A Amer J | 2006 | Journal of the A- merican Oil Chemists' Society2006，83，9： | 1 |
| 11 | Advances in drought resistance of rice 显示文摘 | Farooq M Wahid A Lee D J | 2009 | Critical Reviews in Plant Science2009，28，： | 1 |
| 12 | Comparati veimag- ing of differential pulmonary blood flow in patients with congenital heart disease:magnetic resonance imaging versus lung pei'fusians cintigraphy显示文摘 | Roman KS Kellenberger C J Farooq S | 2005 | Pediatr Radiol2005，35，3： | 1 |
| 13 | Efficacy and safety ofpropofol-mediated sedation for outpatient endoscop- ic retrograde cholangiopancreatography (ERCP) 显示文摘 | YANG J F FAROOQ P ZWILLING K | 2016 | Dig Dis Sci2016，61，6： | 1 |
| 14 | Trajectory Optimization for Air- to- Surface Missiles with Imaging Radars 显示文摘 | Farooq A Limebeer D J | 2002 | Journal of Guid- ance Control and Dynamics2002，25，： | 1 |
| 15 | Trajectory optimization for air-to-surface missiles with imaging radars显示文摘 | Farooq A Limebeer D J N | 2002 | Journal of Guidance Control and Dynamics2002，25，5： | 1 |
| 16 | Separation of methane-nitrogen mixture by pressure swing adsorption for natural gas upgrading显示文摘 | Bhadra S J Farooq S | 2011 | Ind Eng Chem Res2011，50，14： | 1 |
| 17 | Comparative imaging of differential pulmonary blood Now in patients with congenital heart disease: magnetic resonance imaging versus lung perfusion scintigraphy 显示文摘 | ROMAN K S KELLENBERGER C J FAROOQ S | 2005 | Pediatr Radiol2005，35，3： | 1 |
| 18 | Models for Met-Hemocyanin Derivatives: Structural and Spectroscopic Comparisons of Analogous Phenolate and X (X = OH^-, OMe^-, N3^-, Cl^-, OAc^-, OBz^-) Doubly Bridged Dinuclear Copper(Ⅱ) Complexes 显示文摘 | Karlin K D Farooq A Hayes J C | 1987 | Inorg Chem1987，26，： | 1 |
| 19 | Gene expression profile analysis in human hepatocellular carcinoma by cDNA microarray 显示文摘 | Chung E J Sung YK Farooq M | 2002 | MolCells2002，14，3： | 1 |
| 20 | Experimental analysis, modeling and optimization of chromium (VI) removal from aqueous solutions by polymer-enhanced ultrafiltration显示文摘 | Chakraborty S Dasgupta J Farooq U | 2014 | Joumal of Membrane Science2014，456，： | 1 |
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