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| 1 | Celiac disease serology in patients with different pretest probabilities: Is biopsy avoidable?显示文摘AIM: To establish the diagnostic performance of sev-eral serological tests, individually and in combination, for diagnosing celiac disease (CD) in patients with different pretest probabilities, and to explore potential se- rological algorithms to reduce the necessity for biopsy. METHODS: We prospectively performed duodenal biopsy and serology in 679 adults who had either high risk (n = 161) or low risk (n = 518) for CD. Blood samples were tested using six assays (enzyme-linked immunosorbent assay) that detected antibodies to tissue transglutaminase (tTG) and deamidated gliadin peptide (DGP). RESULTS: CD prevalence was 39.1% in the high-risk population and 3.3% in the low-risk group. In high-risk patients, all individual assays had a high diagnostic efficacy [area under receiving operator characteristic curves (AU ROC): 0.968 to 0.999]. In contrast, assays had a lower diagnostic efficacy (AU ROC: 0.835 to 0.972) in the low-risk group. Using assay combinations, it would be possible to reach or rule out diagnosis of CD without biopsy in 92% of cases in both pretest populations. We observed that the new DGP/tTG Screen assay resulted in a surplus compared to more conventional assays in any clinical situation. CONCLUSION: The DGP/tTG Screen assay could be considered as the best initial test for CD. Combinations of two tests, including a DGP/tTG Screen, might be able to diagnose CD accurately in different clinical scenarios making biopsy avoidable in a high proportion of subjects. | Emilia Sugai María L Moreno Hui J Hwang Ana Cabanne Adriana Crivelli Fabio Nach-man Horacio Vázquez Sonia Niveloni Julio Argonz Roberto Mazure Graciela La Motta María E Caniggia Edgardo Smecuol Néstor Chopita Juan C Gómez Eduardo Maurińo Julio C Bai | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 2 | Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia显示文摘 | Andrea Caporali Marco Meloni Christine V?llenkle Desiree Bonci Graciela B. Sala-Newby Roberta Addis Gaia Spinetti Sergio Losa Rachel Masson Andrew H. Baker Reuven Agami Carlos le Sage Gianluigi Condorelli Paolo Madeddu Fabio Martelli Costanza Emanueli | 2011 | Circulation2011，，3： | 2 |
| 3 | A high sensitivity amperometrie biosensor using a monomolecular layer of laccase as bio-recognition element 显示文摘 | Fabio V Antonio C Santa R | 2004 | Biosensors and Bio-electronies2004，20，2： | 1 |
| 4 | In vitro antibacterial activity of men 10700,a new penem antibiotic显示文摘 | Elena P Massimo DL | 1999 | Chemotherapy1999，45，6： | 1 |
| 5 | Bioconversion of D-xylose to xylitol by Debaryomyces hansenii UFV-170:Product formation versus growth显示文摘 | Fabio C S HiLario C M Frederico J V P | 2005 | Process Biochemistry2005，40，： | 1 |
| 6 | Good news for beta-blockers in perioperative medicine显示文摘 | Fabio A Gianpaolo R Paolo V | | 0，，： | 1 |
| 7 | Anaerobic me- tabolism during short and long term storage of kiwifruit 显示文摘 | BOTONDI R RUSSO V FABIO MENCARELLI F | 2012 | Post- harvest Biology & Technology2012，64，： | 1 |
| 8 | Investigation of the thermal degradation of fully aromatic regular polyesters: Poly (oxy-1,4- phenyleneoxyfumaroyl-bis-4-oxybenzoate) 显示文摘 | Fabio Bertini Vjacheslav V Zuev | 2006 | Polymer Degradation and Stability2006，91，： | 1 |
| 9 | Decision support tool for used oil regeneration technologies assessment and se-lection显示文摘 | Olfa K Fabio D G Sanja V | | 0，，： | 1 |
| 10 | Class 1 integron-Bome multiple antimicrob resistance carried by IncF1 and IncL/M plasmids in Salmonella enterica Serotype typhimurium显示文摘 | FABIO T PAOLO V L ANNA M D | 1998 | Antimicrob Agents Chemother1998，42，： | 1 |
| 11 | Sourdough in gluten-free bread making: an ancient technology to solve a novel issue? 显示文摘 | MORONI A V FABIO D B ARENDT E K | 2009 | Food Mocrohiology2009，26，7： | 1 |
| 12 | Class 1 Intergon-Borne Multiple-Antibiotic resistance carried by incfl and incL/M plasmids in Salmonella emerica serotype 7 phimurium显示文摘 | FABIO T PAOLO V IDA L | 1998 | Antimicrobial Agents and Chemotherapy1998，42，12： | 1 |
| 13 | A high sensitivity amperometric biosensor using a monomolecular layer of lacease as biorecognition ele- ment 显示文摘 | Fabio V Antonio C Santa R | 2004 | Biosensors and Bioelectronies2004，20，2： | 1 |
| 14 | The epidemiology of ovari an cancer 显示文摘 | Fabio P Siliva F Carlo V | 1991 | Gynecologic oncology1991，43，： | 1 |
| 15 | Mitochondrial DNA from prehistoric canids highlights relationships between dogs and south-east European wolves 显示文摘 | Fabio V Cristian C Valentina C | 2005 | Mol Biol Evol2005，22，12： | 1 |
| 16 | Investigation of the thermal degradation of fully aromatic regular polyesters: Poly (oxy-1,4-phenyleneoxyfum aroyl-bis-4- oxybenzoate) 显示文摘 | Fabio Bertini V jacheslav V Zue | 2006 | Polymer degradation and Stability2006，91，： | 1 |
| 17 | Changes in the excitability of soleus muscle short latency stretch reflexes during human hopping after 4 weeks of hopping training显示文摘 | Michael V Fabio C Carlo F | 1998 | Eur J Appl Physiol1998，78，： | 1 |
| 18 | A novel pathway for human endothelial cell activation by antiphospholipid! anti-132 glycoprotein I antibodies显示文摘 | Kristi L Allen Fabio V Fonseca Venkaiah Betapudi | 2011 | Blood2011，119，3： | 1 |
| 19 | Thermo-analyses of polyaniline and its derivatives显示文摘 | William F A Everaldo C V Fabio L L | 2010 | Thermochimica Acta2010，502，12： | 1 |
| 20 | Wind-induced salt-wedge intrusion in the Tiber river mouth (Rome-Central Italy) 显示文摘 | FABIO M GIUSEPPE C FRANCESCO L V | 2014 | Environmental Earth Sciences2014，72，4： | 1 |
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