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| 1 | Antitumor activity of fucoidan against diffuse large B cell lymphoma in vitro and in vivo显示文摘Fucoidan 是从棕色的海草孤立的主要 sulfated 多糖之一。在这研究,我们在弥漫的大 B 房间淋巴瘤(DLBCL ) 上决定了 fucoidan 的反癌症活动在 vitro 并且在 vivo 的房间。Fucoidan 在一个剂量依赖者和时间依赖者举止禁止了 DLBCL 细胞的生长,并且 fucoidan 治疗挑起了 G 0/G1 细胞周期拘捕,它被 p21 伴随起来规定和 cyclin D1, Cdk4,和 Cdk6 下面规定。Fucoidan 也在 DLBCL 房间线和主要 DLBCL 房间导致了 caspase 依赖的房间 apoptosis。另外, fucoidan 治疗从线粒体引起了 mitochondrial 膜潜力的损失和细胞色素 c 和导致 apoptosis 因素的版本进 cytosol。Fucoidan 也加强了在杀死 DLBCL 房间的 carfilzomib 的活动。fucoidan 的口头的管理有效地在异种皮移植老鼠模型禁止了肿瘤生长。我们的调查结果作为一个 anti-DLBCL 代理人揭示 fucoidan 的新奇功能,它能在 DLBCL 的临床的治疗被使用。 | Guang Yang Qianqiao Zhang Yuanyuan Kong Bingqian Xie Minjie Gao Yi Tao Hongwei Xu Fenghuang Zhan Bojie Dai Jumei Shi Xiaosong Wu | 2015 | Acta Biochimica et Biophysica Sinica2015，47，11： | 9 |
| 2 | Chemical composition of the ore and occurrence state of the elements in Jingbaoshan platinum-palladium deposit显示文摘The Jingbaoshan platinum-palladium deposit is China’s largest independent PGM (platinum-group met- als) deposit so far discovered. There are eleven kinds of useful components in the ore: Pt, Pd, Os, Ir, Ru, Rh, Au, Ag, Cu, Ni, and Co. The platinum-group elements, gold and silver occur in the form of minerals in ores. twenty-five kinds of precious metal minerals have been found, of which twenty one belong to the platinum-group minerals. The minerals are very small in grain size. Copper occurs mainly as copper sulfide with a small amount of free copper oxide, and the beneficiated copper accounts for 95.21%. Nickel occurs mainly as nickel sulfide, and some nickel silicate and nickel oxide occur in the ore. The beneficiated nickel accounts for 72.03%. Cobalt occurs mainly as co- balt sulfide, and there are some cobalt oxide and other kinds of cobalt. The beneficiated cobalt accounts for 77.58%. | SONG Huanbin HE Mingqin ZHANG Shangzhong YI Fenghuang | 2008 | Chinese Journal Of Geochemistry2008，27，1： | 3 |
| 3 | Proteasome inhibitor carfilzomib interacts synergistically with histone deacetylase inhibitor vorinostat in Jurkat T-leukemia cells显示文摘在现在的学习,我们在 Jurkat T 白血病房间调查了在 proteasome 禁止者 carfilzomib (CFZ ) 和 histone deacetylaseinhibitor vorinostat 之间的相互作用。到 CFZ 与的最低限度地致命的集中的细胞的 Coexposure 很, vorinostat 的 lowconcentration 导致了 synergistic antiproliferative 效果并且在 Jurkat T-leukemiacells 提高了 apoptosis ,与严厉地增加的反应的氧种( ROS )伴随了,在 mitochondrial membranepotential ( MMP )的惹人注目的减少,细胞色素 c 的增加的版本, caspase-9 和-3,和 PARP.The 的劈开的提高的激活联合了 Jurkat 细胞的处理与 ROS 预先对待而且, NAC 也在 apoptotic 房间导致了显著减小,显示为由联合处理的 increasedROS 产生的一个关键角色。另外,联合了逮捕的处理在 G 2-M 的房间周期阶段。这些结果暗示 CFZ 在 Jurkat T 白血病房间与 vorinostat synergistically 交往了,哪个有 vorinostat 的 carfilzomib 的联合可以在对待 T 房间代表新奇策略的 raisedthe 可能性白血病。 | Minjie Gao Lu Gao Yi Tao Jun Hou Guang Yang Xiaosong Wu Hongwei Xu Van S. Tompkins Ying Han Huiqun Wu Fenghuang Zhan Jumei Shi | 2014 | Acta Biochimica et Biophysica Sinica2014，46，6： | 3 |
| 4 | Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo显示文摘 | Shinuel Y W en I Fenghuang Z | 2007 | Blood2007，109，10： | 1 |
| 5 | Influence of heat on protein degradation, ultrastructure and eating quality indicators of pork显示文摘 | FengHuang MingHuang XinglianXu GuanghongZhou | 2011 | Food Agric2011，，3： | 1 |
| 6 | The Role of the Wnt- Signaling Antagonist DKK1 in the Development of Osteolytic Lesions in Multiple Myeloma显示文摘 | Erming T Fenghuang Z John D | 2003 | Engl J Med Dec2003，349，26： | 1 |
| 7 | Laser induced fractal structure on magnetic dielectric thin film显示文摘The Richardson plots method is employed to measure the fractal dimensions D of the surface of magneticdielectric film fractured by excimer laser irradiation near the ablation threshold. It is shown that thefractured surfaces are fractal character. The value of D decreases while the laser pulse number increases.This relation may reflect how the fractured surface changes from irregular structure to regular structurewith laser pulse number. | QihongLou FengHuang | 2003 | Chinese Optics Letters2003，1，4： | 1 |
| 8 | The role of the wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma显示文摘 | Tian BS Fenghuang | | 0，，26： | 1 |
| 9 | Downregulated miR-33b is a novel predictor associated with disease progression and poor prognosis in multiple myeloma显示文摘 | Fei Li Mu Hao Xiaoyan Feng Meirong Zang Yu Qin Shuhua Yi Zengjun Li Yan Xu Lili Zhou Weiwei Sui Shuhui Deng Dehui Zou Fenghuang Zhan Lugui Qiu | 2015 | Leukemia Research2015，，7： | 1 |
| 10 | Low serum mi R ‐19a expression as a novel poor prognostic indicator in multiple myeloma显示文摘 | Mu Hao Meirong Zang Erik Wendlandt Yan Xu Gang An Dasen Gong Fei Li Fang Qi Yanru Zhang Ye Yang Fenghuang Zhan Lugui Qiu | 2015 | Int. J. Cancer2015，，8： | 1 |
| 11 | Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium dentification of candidate molecular markers for ovarian cancer diagnosis and therapy显示文摘 | Santin AD Fenghuang Z Bellone S | 2004 | Cancer2004，11，2： | 1 |
| 12 | The Role of the Wnt-Sig- naling Antagonist DKK1 in the Development of Osteolytic Lesionsin Multiple Myeloma显示文摘 | Erming T Fenghuang Z John D | 2003 | Engl J Med Dec2003，349，26： | 1 |
| 13 | Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium dentification of candidate molecular markers for ovarian cancer diagnosis and therapy显示文摘 | Santin AD Fenghuang Z Bellone S | 2004 | Cancer2004，11，2： | 1 |
| 14 | Differences of ultrasonographic enthesitis between patients with non-radiographic axial spondylarthritis and ankylosing spondylitis显示文摘To the Editor:Spondyloarthritis(SpA)is the umbrella term for a broad spectrum of inflammatory rheumatic diseases with different clinical manifestations and characteristic imaging features.Furthermore,enthesitis is considered a pathological,clinical,and imaginable hallmark of the SpA.In addition to ineffective clinical evaluation techniques of enthesitis,there are useful imaging methods to assess enthesitis,such as whole-body magnetic resonance imaging[1]and ultrasound(US)[2]examination.US has the advantage of real-time imaging and high-cost effectiveness performance.The difference in enthesitis detected by US between non-radiographic-axial SpA(nr-axSpA)and radiographic-axSpA/ankylosing spondylitis(AS)has been seldom researched.Recently,we compared the prevalence and severity of enthesitis between nr-axSpA and AS. | Juan Li Min Wang Fenghuang Xu Guoquan Li Feng Ye | 2022 | Chinese Medical Journal2022，135，21： | 0 |
| 15 | Anti-tumor activity of a lignanic compound from Schisandrapropinqua (Wall) Baill, var sinensis Oliv显示文摘AIM: To discover anti-tumor activity of a lignan from Schisandrapropinqua (Wall) Baill, varsinensis Oliv. METHODS: The cytotoxic activity of compound IE2503 was investigated on several cancer cell lines including solid tumor (HepG2), blood tumor (HL-60), drug resistant tumor (R-HepG2) and one normal cell line NIH3T3. To further prove the apoptosis and investigate the specific cell cycle distribution of HepG2 | FengHUANG Juan-juanHU Li-jiaXU Pei-genXIAO Guan-huaDU | 2004 | Acta Pharmacologica Sinica2004，25，11： | 0 |
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