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5篇 您的检索式:作者名="Florian Hohla"
    题名 作者 年代 出处 被引量
1Targeted therapy in advanced metastatic colorectal cancer: Current concepts and perspectives显示文摘The introduction of new cytotoxic substances as well as agents that target vascular endothelial growth factor(VEGF)and epidermal growth factor receptor(EGFR)signaling has improved clinical outcome of patients withmetastatic colorectal cancer(mCRC).In this review we summarize the most relevant clinical data on VEGF and EGFR targeting regimens in mCRC.The effects of available treatment strategies for mCRC are often temporary,with resistance and disease progression developing in most patients.Thus,new treatment strategies are urgently needed.Some GI peptides including gastrin and gastrin releasing peptide,certain growth factors such as insulin-like growth factor-ⅠandⅡand neuropeptides such as growth hormone releasing hormone(GHRH)are implicated in the growth of CRC.Experimental investigations in CRC with antagonistic analogs of bombesin/gastrin-releasing peptide,GHRH,and with cytotoxic peptides that can be targeted to peptide receptors on tumors,are summarized in the second part of the review.Florian Hohla Thomas Winder Richard Greil Ferenc G Rick Norman L Block rew V Schally 2014World Journal of Gastroenterology2014,20,20:3
2Targeted cytotoxic somatostatin analog AN-162 inhibits growth of human colon carcinomas and increases sensitivity of doxorubicin resistant murine leukemia cells显示文摘Florian Hohla Stefan Buchholz Andrew V. Schally Awtar Krishan Ferenc G. Rick Luca Szalontay Andrea Papadia Gabor Halmos Frank Koster Elmar Aigner Christian Datz Stephan Seitz 2010Cancer Letters2010,,1:1
3Differential expression of GHRH receptor and its splice variant 1 inhuman normal and malignant mucosa of the oesophagus and colon显示文摘Florian Hohla Angelika Moder Ursula Mayrhauser Cornelia Hauser-Kronberger Andrew Schally Jozsef Varga Marta Zarandi Stefan Buchholz Rudolf Huber Elmar Aigner Markus Ritter Christian Datz 2008International Journal of Oncology2008,,1:1
4Female gender may predict response to FOLFIRINOX in patients with unresectablepancreatic cancer: A single institution retrospective review显示文摘Florian Hohla Georg Hopfinger Franz Romeder Gabriel Rinnerthaler Angelika Bezan Stefan St?ttner Cornelia Hauser-Kronberger Hanno Ulmer Richard Greil 2014International Journal of Oncology2014,,1:1
5Systemic effect of catumaxomab in a patient with metastasized colorectal cancer:a case report显示文摘Bezan Angelika Hohla Florian Meissnitzer Thomas 2013BMC Cancer2013,13,1:1
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