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| 1 | Predictors of visual outcome in eyes with choroidal neovascularization secondary to age related macular degeneration treated with intravitreal bevacizumab monotherapy显示文摘AIM:To evaluate the predictors of visual improvement in eyes with naive choroidal neovascularization secondary to age-related macular degeneration (CNV -AMD) treated with intravitreal bevacizumab (IVB) monotherapy. METHODS:Fifty eyes with naive CNV-AMD with pretreatment best-corrected visual acuity (BCVA) better than 20/200 and treated with IVB monotherapy were evaluated. Several variables including age, sex, pre-treatment BCVA, CNV type and lesion size on fluorescein angiogram as well as SD-OCT parameters including pre-treatment central macular thickness (CMT), inner-segment/outer-segment (IS/OS) junction integrity, and external limiting membrane (ELM) integrity were analyzed to predict visual outcome.RESULTS:On univariate regression, pretreatment ELM damage was associated with less visual improvement after treatment (P =0.0145). However, ELM damage predicted only 10% of the visual outcome. On multivariate regression, pretreatment BCVA, IS/OS junction, and ELM integrity on SD-OCT were the significant predictors for the treatment effect and together predicted 37% of visual improvement. CONCLUSION:Pretreatment BCVA, ELM and IS/OS junction integrity on SD-OCT are of significant value inpredicting the visual improvement in naive wet AMD patients treated with IVB monotherapy. | Jay Chhablani Jae SukKim William R Freeman Igor Kozak Hai-Yan Wang Lingyun Cheng | 2013 | International Journal of Ophthalmology(English edition)2013，6，1： | 6 |
| 2 | Learning Low-Level Vision显示文摘 | William T. Freeman Egon C. Pasztor Owen T. Carmichael | 2000 | International Journal of Computer Vision2000，，1： | 3 |
| 3 | Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome显示文摘 | Roy Freeman Wouter Wieling Felicia B. Axelrod David G. Benditt Eduardo Benarroch Italo Biaggioni William P. Cheshire Thomas Chelimsky Pietro Cortelli Christopher H. Gibbons David S. Goldstein Roger Hainsworth Max J. Hilz Giris Jacob Horacio Kaufmann Jens | 2011 | Autonomic Neuroscience: Basic and Clinical2011，，1： | 2 |
| 4 | Enzyme activities in constructed wetlands: Implication for water quality amelioration显示文摘 | Hojeong Kang Chris Freeman Dowon Lee William J. Mitsch | 1998 | Hydrobiologia (-)1998，，1： | 1 |
| 5 | Example-Based Su- per-Resolution 显示文摘 | Freeman William Jones Thouis Pasztor Egon | 2002 | IEEE Computer Graphics and Applications2002，22，2： | 1 |
| 6 | Transoral Incisionless Fundoplication: 2-year Results from the Prospective Multicenter U.S. Study显示文摘 | Bell Reginald C W Barnes William E Carter Bart J Sewell Robert W Mavrelis Peter G Ihde Glenn M Hoddinott Kevin M Fox Mark A Freeman Katherine D Gunsberger Tanja Hausmann Mark G Dargis David Gill Brian DaCosta Wilson Erik Trad Karim S | 2014 | The American Surgeon2014，，11： | 1 |
| 7 | The design and use of steerable filters 显示文摘 | WILLIAM T FREEMAN T ADELSON E H | 1991 | IEEE Trans on Pattern Analysis and Machine Intelligence1991，13，9： | 1 |
| 8 | Therapeutic Hypothermia for Severe Traumatic Brain Injury: A Critically Appraised Topic显示文摘 | Christopher Kramer William D. Freeman Joel S. Larson Charlene Hoffman-Snyder Kay E. Wellik Bart M. Demaerschalk Dean M. Wingerchuk | 2012 | The Neurologist2012，，3： | 1 |
| 9 | Corporate governance: A stakeholder interpretation显示文摘 | Freeman Edward R and Evan William M | 1990 | Journal of Behavioral Economics1990，19，4： | 1 |
| 10 | Motion magnification显示文摘 | Ce Liu Antonio Torralba William T. Freeman Frédo Durand Edward H. Adelson | 2005 | ACM Transactions on Graphics (TOG)2005，，3： | 1 |
| 11 | The Association Between Percent Disruption of the Photoreceptor Inner Segment–Outer Segment Junction and Visual Acuity in Diabetic Macular Edema显示文摘 | Anjali S. Maheshwary Stephen F. Oster Ritchie M.S. Yuson Lingyun Cheng Francesca Mojana William R. Freeman | 2010 | American Journal of Ophthalmology2010，，1： | 1 |
| 12 | Interferon lambda as a potential new therapeutic for hepatitis C显示文摘 | Miller DM Klucher KM Freeman JA Hausman DF Fontana D Williams DE | 2009 | Ann NY Acad Sci2009，1182，： | 1 |
| 13 | Incidence of Additional Primary Cancers in Patients with Invasive Intraductal Papillary Mucinous Neoplasms and Sporadic Pancreatic Adenocarcinomas显示文摘 | Taylor S. Riall Victoria M. Stager William H. Nealon Courtney M. Townsend Yong-fang Kuo James S. Goodwin Jean L. Freeman | 2007 | Journal of the American College of Surgeons2007，，5： | 1 |
| 14 | Computer-Assisted Volumetric Analysis Compared With ABC/2 Method for Assessing Warfarin-Related Intracranial Hemorrhage Volumes显示文摘 | William D. Freeman Kevin M. Barrett Joseph M. Bestic James F. Meschia Daniel F. Broderick Thomas G. Brott | 2008 | Neurocritical Care2008，，3： | 1 |
| 15 | Image and depth from a conventional camera with a coded aperture显示文摘 | Anat Levin Rob Fergus Frédo Durand William T. Freeman | 2007 | ACM Transactions on Graphics (TOG)2007，，3： | 1 |
| 16 | AIDS-related optic neuropathy: a histological, virological and ultrastructural study显示文摘 | Alfredo A. Sadun Jay S. Pepose Michele C. Madigan Keith A. Laycock Wendy N. Tenhula William R. Freeman | 1995 | Graefe’s Archive for Clinical and Experimental Ophthalmology1995，，7： | 1 |
| 17 | Responsivity nonuniformity limited performance of infrared staring cameras显示文摘 | Jonathan M Mooney Freeman D Shepherd William SEwing | 1989 | Opt Eng1989，28，11： | 1 |
| 18 | Enzyme activities in constructed wetlands: Implication for water quality amelioration显示文摘 | Hojeong Kang Chris Freeman Dowon Lee William J. Mitsch | 1998 | Hydrobiologia (-)1998，，1： | 1 |
| 19 | Does prophylactic administration of corticosteroid reduce the risk and severity of post-ERCP pancreatitis: A randomized, prospective, multicenter study显示文摘 | Stuart Sherman Urszula Blaut James L. Watkins Jeffrey Barnett Martin Freeman Joseph Geenen Michael Ryan Harrison Parker James T. Frakes Evan L. Fogel William B. Silverman Kulwinder S. Dua Giuseppe Aliperti Paul Yakshe Michael Uzer Whitney Jones John Goff | 2003 | Gastrointestinal Endoscopy2003，，1： | 1 |
| 20 | Eosinophilia associatedwith disorders of immune deficiency or immunedysregulation 显示文摘 | Williams KW Milner JD Freeman AF | 2015 | Immunol Allergy Clin North Am2015，35，3： | 1 |
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