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| 1 | Investigation of Myocardial Stunning after Cardiopulmonary Resuscitation in Pigs显示文摘Objective To investigate cardiac function and myocardial perfusion during 48 h after cardiopulmonary resuscitation (CPR), further to test myocardial stunning and seek indicators for long‐term survival after CPR. Methods After 4 min of untreated ventricular fibrillation, fifteen anesthetized pigs were studied at baseline and 2 h, 4 h, 24 h, and 48 h after restoration of spontaneous circulation (ROSC). Hemodynamic data, echocardiography and gated‐single photon emission computed tomography myocardial perfusion images were carried out. Results Mean arterial pressure (MAP), coronary perfusion pressure (CPP) and cardiac troponin I (CTNI) showed significant differences between eventual survival animals and non‐survival animals at 4 h after ROSC (109.2±10.7 mmHg vs. 94.8±12.3 mmHg, P=0.048; 100.8±6.9 mmHg vs. 84.4±12.6 mmHg, P=0.011; 1.60±0.13 ug/L vs. 1.75±0.10 ug/L, P=0.046). Mitral valve early‐to‐late diastolic peak velocity ratio, mitral valve deceleration time recovered 24 h; ejection faction and the summed rest score recovered 48 h after ROSC. Conclusion Cardiac systolic and early active relaxation dysfunctions were reversible within survival animals; cardiac stunning might be potentially adaptive and protective after CPR. The recovery of MAP, CPP, and CTNI could be the indicators for long‐term survival after CPR. | YANGLin LI ChunSheng GAO ChunJin WANG Shuo JI XianFei SU ZhiYu | 2011 | Biomedical and Environmental Sciences2011，24，2： | 8 |
| 2 | TBM penetration rate prediction based on the long short-term memory neural network显示文摘Tunnel boring machines(TBMs)are widely used in tunnel engineering because of their safety and efficiency.The TBM penetration rate(PR)is crucial,as its real-time prediction can reflect the adaptation of a TBM under current geological conditions and assist the adjustment of operating parameters.In this study,deep learning technology is applied to TBM performance prediction,and a PR prediction model based on a long short-term memory(LSTM)neuron network is proposed.To verify the performance of the proposed model,the machine parameters,rock mass parameters,and geological survey data from the water conveyance tunnel of the Hangzhou Second Water Source project were collected to form a dataset.Furthermore,2313 excavation cycles were randomly composed of training datasets to train the LSTM-based model,and 257 excavation cycles were used as a testing dataset to test the performance.The root mean square error and the mean absolute error of the proposed model are 4.733 and 3.204,respectively.Compared with Recurrent neuron network(RNN)based model and traditional time-series prediction model autoregressive integrated moving average with explanation variables(ARIMAX),the overall performance on proposed model is better.Moreover,in the rapidly increasing period of the PR,the error of the LSTM-based model prediction curve is significantly smaller than those of the other two models.The prediction results indicate that the LSTM-based model proposed herein is relatively accurate,thereby providing guidance for the excavation process of TBMs and offering practical application value. | Boyang Gao RuiRui Wang Chunjin Lin Xu Guo Bin Liu Wengang Zhang | 2021 | Underground Space2021，6，6： | 4 |
| 3 | Clinical study on the related markers of blood coagulation in the patients with ANFH after SARS显示文摘The aim of this research was to investigate the blood coagulation function in the patients with avascular necrosis of the femoral head(ANFH)after severe acute respiratory syndrome(SARS).The expression of CD31,CD61,CD62p,CD63 and PAC-1 on platelet membrane was measured respectively by flowcytometry,and the plasma prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT)and fibrinogen(Fbg)were mea-sured by blood clotting instrument in 26 patients with ANFH after SARS and in 17 healthy adults.The expression of CD31,CD61,CD 62p,CD63 and PAC-1 on platelet membrane in 26 patients was all lower than that in 17 healthy subjects(P<0.01).The levels of PT,APTT,TT and Fbg in 26 patients were all normal.There is no significant difference(P>0.05)in those markers between patients and 17 healthy adults.The blood may not be in hypercoagulable state in patients with ANFH after SARS. | WU Lianhua GAO Chunjin WANG Guozhong YANG Lin HOU Xiaomin GE Huan XIA Chengqing QI Man | 2007 | Frontiers of Medicine2007，1，4： | 2 |
| 4 | Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury显示文摘 | Jing Yang Guozhong Wang Chunjin Gao Guiqiang Shao Nan Kang | 2013 | Life Sciences (-)2013，，25： | 1 |
| 5 | Effects of stromal cell derived factor-1 and CXCR4 on the promotionof neovascularization by hyperbaric oxygen treatment in skin flaps显示文摘 | Xuehua Liu Fang Liang Jing Yang Zhuo Li Xiaomin Hou Youbin Wang Chunjin Gao | 2013 | Molecular Medicine Reports2013，，4： | 1 |
| 6 | PBL教学法在高压氧医学科教学查房中的实践显示文摘目的探讨PBL教学法在高压氧医学科教学查房中的应用效果,探索更符合高压氧医学科特点的教学查房模式。方法选取2021年3月1日-2021年5月31日在某院高压氧科进行临床实习的实习医师32人,采用信封法随机分为2组。实验组16人,采用以问题为基础的教学查房,对照组16人,采用传统教学查房模式。通过考核及问卷调查评价教学效果。结果实验组病例分析成绩高于与对照组(分别为88.4±3.5分和78.8±5.2分),差异具有统计学意义(P<0.05),基础知识成绩2组间差异无统计学意义,分别为(85.9±3.6)分和(84.1±4.3)分,P>0.05。75%的实习生对PBL教学模式总体评价为很满意或比较满意。结论PBL教学查房可以提高实习医师病例分析能力、锻炼临床思维,促使实习医师更好的掌握高压氧科常见疾病的诊治。 | 张奕 刘雪华 高宇 梁芳 杨琳 杨晶 Gao Chunjin | 2022 | 中国病案2022，23，11： | 1 |
| 7 | Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury显示文摘 | Jing Yang Guozhong Wang Chunjin Gao Guiqiang Shao Nan Kang | 2013 | 2013 (25-2)2013，，25： | 1 |
| 8 | Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury显示文摘 | Jing Yang Guozhong Wang Chunjin Gao | | 0，，93： | 1 |
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