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| 1 | Cryogenic minimum quantity lubrication machining: from mechanism to application显示文摘Cutting fluid plays a cooling-lubrication role in the cutting of metal materials.However,the substantial usage of cutting fluid in traditional flood machining seriously pollutes the environment and threatens the health of workers.Environmental machining technologies,such as dry cutting,minimum quantity lubrication(MQL),and cryogenic cooling technology,have been used as substitute for flood machining.However,the insufficient cooling capacity of MQL with normal-temperature compressed gas and the lack of lubricating performance of cryogenic cooling technology limit their industrial application.The technical bottleneck of mechanical-thermal damage of difficult-to-cut materials in aerospace and other fields can be solved by combining cryogenic medium and MQL.The latest progress of cryogenic minimum quantity lubrication(CMQL)technology is reviewed in this paper,and the key scientific issues in the research achievements of CMQL are clarified.First,the application forms and process characteristics of CMQL devices in turning,milling,and grinding are systematically summarized from traditional settings to innovative design.Second,the cooling-lubrication mechanism of CMQL and its influence mechanism on material hardness,cutting force,tool wear,and workpiece surface quality in cutting are extensively revealed.The effects of CMQL are systematically analyzed based on its mechanism and application form.Results show that the application effect of CMQL is better than that of cryogenic technology or MQL alone.Finally,the prospect,which provides basis and support for engineering application and development of CMQL technology,is introduced considering the limitations of CMQL. | Mingzheng LIU Changhe LI Yanbin ZHANG Qinglong AN Min YANG Teng GAO Cong MAO Bo LIU Huajun CAO Xuefeng XU Zafar SAID Sujan DEBNATH Muhammad JAMIL Hafz Muhammad ALI Shubham SHARMA | 2021 | Frontiers of Mechanical Engineering2021，16，4： | 8 |
| 2 | 96-Week Treatment of Tenofovir Amibufenamide and Tenofovir Disoproxil Fumarate in Chronic Hepatitis B Patients显示文摘Background and Aims:Tenofovir amibufenamide(TMF)is a novel phosphoramidated prodrug of tenofovir with nonin-ferior efficacy and better bone and renal safety to tenofovir disoproxil fumarate(TDF)in 48 weeks of treatment.Here,we update 96-week comparison results.Methods:Patients with chronic hepatitis B were assigned(2:1)to receive either 25 mg TMF or 300 mg TDF with matching placebo for 96 weeks.The virological suppression was defined as HBV DNA levels<20 IU/mL at week 96.Safety was evaluated thoroughly with focusing on bone,renal,and metabolic pa-rameters.Results:Virological suppression rates at week 96 were similar between TMF and TDF group in both HBeAg-positive and HBeAg-negative populations.Noninferior efficacy was maintained in the pooled population,while it was first achieved in patients with HBV DNA≥7 or 8 log10 IU/mL at baseline.Non-indexed estimated glomerular filtration rate for renal safety assessment was adopted,while a smaller decline of which was seen in the TMF group than in the TDF group(p=0.01).For bone mineral density,patients receiv-ing TMF displayed significantly lower reduction levels in the densities of spine,hip,and femur neck at week 96 than those receiving TDF.In addition,the lipid parameters were stable after week 48 in all groups while weight change still showed the opposite trend.Conclusions:TMF maintained similar efficacy at week 96 compared with TDF with continued superior bone and renal safety profiles(NCT03903796). | Zhihong Liu Qinglong Jin Yuexin Zhang Guozhong Gong Guicheng Wu Lvfeng Yao Xiaofeng Wen Zhiliang Gao Yan Huang Daokun Yang Enqiang Chen Qing Mao Shide Lin Jia Shang Huanyu Gong Lihua Zhong Huafa Yin Fengmei Wang Peng Hu Qiong Wu Chao Pan Wen Jia Chuan Li Chang’an Sun Junqi Niu Jinlin Hou TMF Study Group | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 3 |
| 3 | Fiber-reinforced composites in milling and grinding:machining bottlenecks and advanced strategies显示文摘Fiber-reinforced composites have become the preferred material in the fields of aviation and aerospace because of their high-strength performance in unit weight.The composite components are manufactured by near netshape and only require finishing operations to achieve final dimensional and assembly tolerances.Milling and grinding arise as the preferred choices because of their precision processing.Nevertheless,given their laminated,anisotropic,and heterogeneous nature,these materials are considered difficult-to-machine.As undesirable results and challenging breakthroughs,the surface damage and integrity of these materials is a research hotspot with important engineering significance.This review summarizes an up-to-date progress of the damage formation mechanisms and suppression strategies in milling and grinding for the fiber-reinforced composites reported in the literature.First,the formation mechanisms of milling damage,including delamination,burr,and tear,are analyzed.Second,the grinding mechanisms,covering material removal mechanism,thermal mechanical behavior,surface integrity,and damage,are discussed.Third,suppression strategies are reviewed systematically from the aspects of advanced cutting tools and technologies,including ultrasonic vibration-assisted machining,cryogenic cooling,minimum quantity lubrication(MQL),and tool optimization design.Ultrasonic vibration shows the greatest advantage of restraining machining force,which can be reduced by approximately 60%compared with conventional machining.Cryogenic cooling is the most effective method to reduce temperature with a maximum reduction of approximately 60%.MQL shows its advantages in terms of reducing friction coefficient,force,temperature,and tool wear.Finally,research gaps and future exploration directions are prospected,giving researchers opportunity to deepen specific aspects and explore new area for achieving high precision surface machining of fiber-reinforced composites. | Teng GAO Yanbin ZHANG Changhe LI Yiqi WANG Yun CHEN Qinglong AN Song ZHANG Hao Nan LI Huajun CAO Hafiz Muhammad ALI Zongming ZHOU Shubham SHARMA | 2022 | Frontiers of Mechanical Engineering2022，17，2： | 3 |
| 4 | Tumor inhibitory effect of YCP (a marine fugal polysaccharide) (I)显示文摘 | Chen Zhen Guo Qinglong Gao Xiangdong | 2005 | Chin J Nat Med2005，3，6： | 1 |
| 5 | Introducing Degree Days to Building Thermal Climatic Zoning in China显示文摘Building thermal climatic zoning is a key issue in building energy efficiency.Heating degree days(HDD) and cooling degree days(CDD) are often employed as indexes to represent the heating and cooling energy demand in climatic zoning.However,only using degree days may oversimplify the climatic zoning in regions with complex climatic conditions.In the present study,the application of degree days to current building thermal climatic zoning in China was assessed based on performance simulations.To investigate the key indexes for thermal climatic zoning,the climate characteristics of typical cities were analyzed and the relationships between the climate indexes and heating/cooling demand were obtained.The results reveal that the annual cumulative heating load had a linear correlation with HDD 18 only in regions with small differences in altitude.Therefore,HDD is unsuitable for representing the heating demand in regions with large differences in altitude.A comprehensive index(winter climatic severity index) should be employed instead of HDD,or complementary indexes(daily global solar radiation or altitude) could be used to further divide climate zones.In the current official climatic zoning,the base temperature of 26℃ for CDD is excessively high.The appropriate base temperature range is 18℃ to 22℃.This study provides a reference for selecting indexes to improve thermal climatic zoning in regions with similar climates. | LIU Yan WEN Zeqiu LYU Kailin YANG Liu LIU Jiaping DONG Hong GAO Qinglong | 2023 | Journal of Thermal Science2023，32，3： | 1 |
| 6 | Tumor inhibitory effect of YCP (a marine fugal polysaccharide)(I)显示文摘 | Chen Zhen Guo Qinglong Gao Xiangdong | 2005 | Chin J Nat Med2005，3，6： | 1 |
| 7 | Tumor inhibitory effect of YCP(a marine fugal polysaccharide) (I)显示文摘 | Chen Zhen Guo Qinglong Gao Xiangdong | 2005 | Chin J Nat Med2005，3，6： | 1 |
| 8 | Electrodeposited iodide ions imprinted polypyrrole@bismuth oxyiodide film for an electrochemically switched renewable extractor towards iodide ions显示文摘Effective extraction and regeneration of radioactive iodide is one of urgent concerns for the safe utilization of nuclear energy.As a novel environmentally benign ion separation technique,electrochemically switched ion extraction(ESIE)process can be applied for effective capture and recovery of iodide ions(I^(-)).Herein,a novel kelp seaweed-like core/shell I^(-)imprinted polypyrrole@bismuth oxyiodide(PPy/I^(-)@BiOI)composite film is successfully prepared for the selective I^(-)capture in the ESIE system.It is found that the I^(-)can be easily trapped in the PPy/I^(-)@BiOI film after I^(-)is in situ desorbed from the film by an electrochemical reduction process since it offers particular electroactive binding sites for I^(-)extraction.The I^(-)imprinted PPy/I^(-)@BiOI film displays an extraction capacity as high as 325.2 mg·g^(-1)for I^(-)with favorable stability.In particular,the extraction and desorption of I^(-)is achieved by adjusting the redox potential and the pristine PPy/I^(-)@BiOI film can be regenerated and reused for multiple times without decrease in extraction capacity.It is expected that such a PPy/I^(-)@BiOI film would be useful as an electrochemically switched renewable extractor that could capture and regenerate I^(-)from radioactive water. | Fengfeng Gao Jinhua Luo Xuefeng Zhang Xiaogang Hao Guoqing Guan Zhong Liu Jun Li Qinglong Luo | 2022 | Chinese Journal of Chemical Engineering2022，35，9： | 0 |
| 9 | Getting insights into gas-phase sulfation effect on catalytic performance of praseodymium oxides in NH_(3)-SCR of NO显示文摘Sulfation treatment has been widely used to promote the catalytic performance of ceria(CeO_(2))based catalysts for the selective catalytic reduction of NO by NH_(3)(NH_(3)-SCR of NO).Praseodymium oxide(PrO_(x)),another commonly used rare earth material with similar structural properties as CeO_(2),also shows satistactory redox properties due to the facile redox cycle of Pr^(3+)■Pr^(4+).In this work,gas phase sulfation treatment with varied duration was performed on PrO_(x) at 200℃,and the NH_(3)-SCR activity of sulfated PrO_(x) was evaluated.Based on the results of systematic characterizations(e.g.,N_(2)-physisorption,NH_(3) oxidation,NO oxidation,in situ diffuse Fourier transform infrared spectroscopy),it is revealed that the catalytic performance of sulfated PrO_(x)is highly dependent on the sulfation time(or the amount of sulfate species deposited on PrO_(x)),which has a significant impact on the competitive reaction between NH_(3) oxidation and NH_(3)-SCR of NO,thus determining the NH_(3)-SCR activity of PrO_(x).This work provides new insight into tuning the interaction between PrO_(x) surface and reactants(NO,NH_(3))via sulfation treatment,which cam guide the design and application of PrO_(x)based catalysts for NH_(3)-SCR of NO in the future. | Yandi Cai Peng Yang Qinglong Liu Kaili Ma Wenxin Ma Wang Song Qiuhui Qian Fei Gao Wei Tan Lin Dong | 2023 | Journal of Rare Earths2023，41，6： | 0 |
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