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| 1 | Pre-diagnostic levels of adiponectin and soluble vascular cell adhesion molecule-1 are associated with colorectal cancer risk显示文摘AIM: To examine the relationships between pre-diagnostic biomarkers and colorectal cancer risk and assess their relevance in predictive models.METHODS: A nested case-control study was designed to include all first primary incident colorectal cancer cases diagnosed between inclusion in the SUpplémentation en VItamines et Minéraux AntioXydants cohort in 1994 and the end of follow-up in 2007. Cases (n = 50) were matched with two randomly selected controls (n = 100). Conditional logistic regression models were used to investigate the associations between pre-diagnostic levels of hs-CRP, adiponectin, leptin, soluble vascular cell adhesion molecule-1 (sVCAM-1), soluble intercellular adhesion molecule-1, E-selectin, monocyte chemoattractant protein-1 and colorectal cancer risk. Area under the receiver operating curves (AUC) and relative integrated discrimination improvement (RIDI) statistics were used to assess the discriminatory potential of the models. RESULTS: Plasma adiponectin level was associated with decreased colorectal cancer risk (P for linear trend = 0.03). Quartiles of sVCAM-1 were associated with increased colorectal cancer risk (P for linear trend = 0.02). No association was observed with any of the other biomarkers. Compared to standard models with known risk factors, those including both adiponectin and sVCAM-1 had substantially improved performance for colorectal cancer risk prediction (P for AUC improvement = 0.01, RIDI = 26.5%). CONCLUSION: These results suggest that pre-diagnostic plasma adiponectin and sVCAM-1 levels are associated with decreased and increased colorectal cancer risk, respectively. These relationships must be confirmed in large validation studies. | Mathilde Touvier Léopold Fezeu Namanjeet Ahluwalia Chantal Julia Nathalie Charnaux Angela Sutton Caroline Méjean Paule Latino-Martel Serge Hercberg Pilar Galan Sébastien Czernichow | 2012 | World Journal of Gastroenterology2012，18，22： | 15 |
| 2 | 膳食因素对高血压发生的影响:NutriNet-Santé队列前瞻性分析显示文摘膳食是高血压发展的主要影响因素之一。这方面的数据主要来源于横断面研究。该研究旨在通过大型队列研究调查营养因素及坚持高血压防治膳食与高血压发生之间的关系。在80 426名参加NutriNet-Santé队列研究的法国成年人中前瞻性调查高血压发生率。基线及之后的每年都进行社会人口学问卷、生活健康方式问卷和3份24h记录评定膳食消费的调查。 | 陈嘉睿 叶鹏 Lelong H Blacher J Baudry J Adriouch S Galan P Fezeu L Hercberg S Kesse-Guyot E | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 3 | Statin Treatment Is Associated with Reduction in Serum Levels of Receptor Activator of NF- κ B Ligand and Neutrophil Activation in Patients with Severe Carotid Stenosis显示文摘 | Sébastien Lenglet Alessandra Quercioli Mathias Fabre Katia Galan Graziano Pelli Alessio Nencioni Inga Bauer Aldo Pende Magaly Python Maria Bertolotto Giovanni Spinella Bianca Pane Domenico Palombo Franco Dallegri Fran?ois Mach Nicolas Vuilleumier Fabrizio | 2014 | Mediators of Inflammation2014，，： | 2 |
| 4 | Speech/music classification based on distributed evolutionary fuzzy logic for intelligent audio coding显示文摘 | Munoz J E Reyes N R Galan S G | 2007 | Pattern Recognition and Image2007，4478，： | 1 |
| 5 | Spontaneous extrusion of a stainless steel glaucoma drainage implant (Ex-PRESS)显示文摘 | Tavolato M Babighian S Galan A | 2006 | Eur J Ophthalmol2006，16，： | 1 |
| 6 | Cross-amplification tests of ungulate primers in roe deer ( Capreolus capreolus) to develop a multiplex panel of 12 microsatellite loci 显示文摘 | Galan M Cosson J F Aulagnier S | 2003 | Molecular Ecology Notes2003，3，1： | 1 |
| 7 | Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial显示文摘 | Zoungas S de Galan BE Ninomiya T | 2009 | Diabetes Care2009，32，11： | 1 |
| 8 | Serum concentrations of β - carotene, vitamins C and E, zinc and selenimn are influenced by sex, age, diet, smoking status, alcohol consumption and corpulence in a general French adult population显示文摘 | Galan P Viteri FE Bertrais S | 2005 | Eur J Clin Nutr2005，59，： | 1 |
| 9 | Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes:New results from the ADVANCE trial显示文摘 | Zoungas S de Galan BE Ninomiya T | | 0，，： | 1 |
| 10 | Epidural analgesia and the rate of cesarean delivery显示文摘 | Rodriguez Hesles Valavdzquez C Manzanares Galan S | | 0，，9： | 1 |
| 11 | The activity of tissue enzymes in iron-deficient rat and man: an overview 显示文摘 | Galan P Hercberg S Touitou Y | 1984 | Comp Biochem Physiol B1984，77，4： | 1 |
| 12 | Doxorubicin treatment activates a Z - VAD - sensitive caspase, which causes deltapsim loss, caspase- 9 activity, and apoptosis in Jurkat cell显示文摘 | Gamen S Anel A Perez - Galan P | 2000 | Exp Cell Res2000，258，1： | 1 |
| 13 | Sulfonamide antibiotics in natural and treated waters: environmental and human health risks显示文摘 | GALAN M J G DIAZ-CRUZ M S BARCELO D | 2012 | Handbook of Environmental Chemis- try2012，11，： | 1 |
| 14 | One-layer neural net- work controller with preprocessed inputs for autonomous underwater vehicle显示文摘 | JAGANNATHAN S GALAN G | 2003 | IEEE Trans on Vehicular Technol- ogy2003，52，5： | 1 |
| 15 | Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial显示文摘 | Galan P kesse-Guyot E Czemichow S | 2010 | BMJ2010，341，29： | 1 |
| 16 | Mercury in the Southern North Sea and Scheldt estuary显示文摘 | M Leermakers S Galletti S De Galan N Brion W Baeyens | 2001 | Marine Chemistry2001，，3： | 1 |
| 17 | Liver transplantation using uncontrolled nonheart-beating donors under normothermic extracorporeal membrane oxygenation显示文摘 | Jiménez Galanes S Meneu Diaz MJC Elola Olaso AM | 2009 | Liver Transplant2009，15，： | 1 |
| 18 | Determination of D-fagomine in buckwheat and mulberry by cation exchange HPLC/ESI-Q-MS 显示文摘 | Amezqueta S Galan E Fuguet E | 2012 | Anal Bioanal Chem2012，402，5： | 1 |
| 19 | Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and mierovascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial显示文摘 | Zoungas S de Galan BE Ninomiya T | 2009 | Diabetes Care2009，32，11： | 1 |
| 20 | Efficacy and safety of ab interno excimer laser trabeculotomy in primary open-angle glaucoma:two years of follow-up显示文摘 | BABIGHIAN S RAPIZZI E GALAN A | 2006 | Ophthalmologica2006，220，5： | 1 |
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