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| 1 | Role of Aedes aegypti and Aedes albopictus during the 2011 dengue fever epidemics in Hanoi, Vietnam显示文摘Objective: To record the human cases of dengue fever(DF) and investigate the Aedes mosquito species circulating during the Hanoi 2011 DF epidemics. Methods: 24 different outbreak points were recorded in 8 districts between August and December 2011. Results: 140 patients were hospitalized following dengue diagnostic with a predominance of males(59.3%) and the 15-34 age class. Only DENV-1(11.27%) and DENV-2(88.73%) serotypes were detected in human samples. Mosquito sampling performed in and around patients households revealed the predominance of Aedes aegypti(95.15%) versus Aedes albopictus(4.85%). There is a positive correlation between the population density of Aedes aegypti and the number of human cases and duration of outbreaks. Conclusions: This was not observed for Aedes albopictus. 3 pools of Aedes aegypti were positive with dengue virus, two with DENV-1 and one with DENV-2. | Pham Thi Kim Lien Vu Trong Duoc Laurent Gavotte Emmanuel Cornillot Phan Thi Nga Laurence Briant Roger Frutos Tran Nhu Duong | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，7： | 2 |
| 2 | Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host显示文摘 | Xi Z Gavotte L Xie Y | 2008 | BMC Genomics2008，2，9： | 1 |
| 3 | Genetic diversity and lineage dynamic of dengue virus serotype 1 (DENV-1) in Cambodia显示文摘 | Veasna Duong Cameron Simmons Laurent Gavotte Alain Viari Sivuth Ong Ngan Chantha Niall J. Lennon Bruce W. Birren Sirenda Vong Jeremy J. Farrar Matthew R. Henn Vincent Deubel Roger Frutos Philippe Buchy | 2013 | Infection, Genetics and Evolution2013，，： | 1 |
| 4 | Complex dynamic of dengue virus serotypes 2 and 3 in Cambodia following series of climate disasters显示文摘 | Veasna Duong Matthew R. Henn Cameron Simmons Chantha Ngan Bunthin Y Laurent Gavotte Alain Viari Sivuth Ong Rekol Huy Niall J. Lennon Sowath Ly Sirenda Vong Bruce W. Birren Jeremy J. Farrar Vincent Deubel Roger Frutos Philippe Buchy | 2013 | Infection, Genetics and Evolution2013，，： | 1 |
| 5 | Artificial triple Wolbachia infection in Aedes dbopictus yields a new pattern of unidirectional cytoplasmic incompatibility显示文摘 | Fu Y Gavotte L Mercer DR | 2010 | Appl Environ Micmbiol2010，76，17： | 1 |
| 6 | Geographic distribution and prevalence of human echinococcosis at the township level in the Tibet Autonomous Region显示文摘Background Echinococcosis,a zoonotic parasitic disease,is caused by larval stages of cestodes in the Echinococcus genus.Echinococcosis is highly prevalent in ten provinces/autonomous regions of western and northern China.In 2016,an epidemiological survey of Tibet Autonomous Region(TAR)revealed that the prevalence of human echinococcosis was 1.66%,which was much higher than the average prevalence in China(0.24%).Therefore,to improve on the current prevention and control measures,it is important to understand the prevalence and spatial distribution characteristics of human echinococcosis at the township level in TAR.Methods Data for echinococcosis cases in 2018 were obtained from the annual report system of echinococcosis of Tibet Center for Disease Control and Prevention.Diagnosis had been performed via B-ultrasonography.The epidemic status of echinococcosis in all townships in TAR was classified according to the relevant standards of population prevalence indices as defined in the national technical plan for echinococcosis control.Spatial scan statistics were performed to establish the geographical townships that were most at risk of echinococcosis.Results In 2018,a total of 16,009 echinococcosis cases,whose prevalence was 0.53%,were recorded in 74 endemic counties in TAR.Based on the order of the epidemic degree,all the 692 townships were classified from high to low degrees.Among them,127 townships had prevalence rates≥1%.The high prevalence of human echinococcosis in TAR,which is associated with a wide geographic distribution,is a medical concern.Approximately 94.65%of the villages and towns reported echinococcosis cases.According to spatial distribution analysis,the prevalence of human echinococcosis was found to be clustered,with the specific clustering areas being identified.The cystic echinococcosis primary cluster covered 88 townships,while that of alveolar echinococcosis’s covered 38 townships.Conclusions This study shows spatial distributions of echinococcosis with different epidemic degrees in 692 townships of TAR and high-risk cluster areas at the township level.Our findings indicate that strengthening the echinococcosis prevention and control strategies in TAR should directed at townships with a high prevalence and high-risk clustering areas. | Liying Wang Gongsang Quzhen Min Qin Zehang Liu Huasheng Pang Roger Frutos Laurent Gavotte | 2022 | Infectious Diseases of Poverty2022，11，1： | 1 |
| 7 | A survey of the bacteriophage WO in the en- dosymbiotic bacteria Wolbachia显示文摘 | GAVOTTE L | 2007 | Molecular Biology and Evo- lution2007，24，2： | 1 |
| 8 | Tuberculosis Prevalence Trends from a Predictive Modelling Study-10 High-Burden Countries,1980-2035显示文摘Summary What is already known about this topic?Given the challenges presented by drug-resistant strains of tuberculosis(TB)and the rising mobility of the population,achieving the objective of eradicating TB appears uncertain. | Qiuping Chen Qiao Liu Kangguo Li Laurent Gavotte Roger Frutos Tianmu Chen | 2024 | China CDC weekly2024，6，12： | 0 |
| 9 | Transmissibility of tuberculosis among students and non-students:an occupational-specific mathematical modelling显示文摘Background: Recently, despite the steady decline in the tuberculosis (TB) epidemic globally, school TB outbreaks have been frequently reported in China. This study aimed to quantify the transmissibility ofMycobacterium tuberculosis (MTB) among students and non-students using a mathematical model to determine characteristics of TB transmission.Methods: We constructed a dataset of reported TB cases from four regions (Jilin Province, Xiamen City, Chuxiong Prefecture, and Wuhan City) in China from 2005 to 2019. We classified the population and the reported cases under student and non-student groups, and developed two mathematical models [nonseasonal model (Model A) and seasonal model (Model B)] based on the natural history and transmission features of TB. The effective reproduction number (R(eff)) of TB between groups were calculated using the collected data.Results: During the study period, data on 456,423 TB cases were collected from four regions: students accounted for 6.1% of cases. The goodness-of-fit analysis showed that Model A had a better fitting effect (P < 0.001). The average R_(eff) of TB estimated from Model A was 1.68 [interquartile range (IQR): 1.20–1.96] in Chuxiong Prefecture, 1.67 (IQR: 1.40–1.93) in Xiamen City, 1.75 (IQR: 1.37–2.02) in Jilin Province, and 1.79 (IQR: 1.56–2.02) in Wuhan City. The average R_(eff) of TB in the non-student population was 23.30 times (1.65/0.07) higher than that in the student population.Conclusions: The transmissibility of MTB remains high in the non-student population of the areas studied, which is still dominant in the spread of TB. TB transmissibility from the non-student-to-student-population had a strong influence on students. Specific interventions, such as TB screening, should be applied rigorously to control and to prevent TB transmission among students. | Qiuping Chen Shanshan Yu Jia Rui Yichao Guo Shiting Yang Guzainuer Abudurusuli Zimei Yang Chan Liu Li Luo Mingzhai Wang Zhao Lei Qinglong Zhao Laurent Gavotte Yan Niu Roger Frutos Tianmu Chen | 2022 | Infectious Diseases of Poverty2022，11，6： | 0 |
| 10 | Surveillance of dengue and chikungunya infection in Dong Thap,Vietnam:A 13-month study显示文摘Objective:To establish a surveillance in Dong Thap,at the border with Cambodia by assessing the presence of DHNV serotypes and CHIKV among patients hospitalized at Dong Thap general hospital.Methods:Cross-sectional descriptive analysis was conducted on a cohort of 131 patients hospitalized with acute fever and symptoms compatible with dengue or chikungunya.The study was conducted from January 2012 to February 2013.The full clinical picture was established as well as serological and molecular detection.Serological analysis was sequentially performed on blood samples collected on admission and an average of seven days after admission.The detection of IgM antibody to DENV was performed by IgM capture ELTSA and the detection of DENV and CHIKV RNA was done by reverse-transcription multiplex PCR.Results:101 patients out of 131(77%) were confirmed with dengue.All four dengue serotypes were detected with a predominance of DENV2 and DENV4.No chikungunya infection was detected although reported in neighboring Cambodia.A differential efficiency of serological dengue detection was observed.Efficiency was 29%upon admission and 53%after seven days on the same patients.30 patients out of 131(23%) were negative with both DENV and CHIKV.Conclusions:Dengue is at risk of being underestimated and chikungunya is not systematically detected.Changes in detection and surveillance procedures are therefore discussed to increase efficiency of dengue detection and continue the monitoring the emergence of CHIKV in Dong Thap province and in Vietnam. | Pham Thi Kim Lien Laurence Briant Truong Ba Tang Bui Minh Trang Laurent Gavotte Emmanuel Comillot Vu Trong Duoc Tran Nhu Duong Roger Frutos Phan Thi Nga | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，1： | 0 |
| 11 | Assessment of echinococcosis control in Tibet Autonomous Region,China显示文摘Background:In China the highest prevalence of echinococcosis is in Tibet Autonomous Region(TAR).The government has issued documents and implemented comprehensive prevention and control measures focusing on controlling the source of infection of echinococcosis.It was very important to understand the implementation and effect of infectious source control measures.The purpose of this study was to examine the implementation of measures to control infectious source(domestic and stray dogs)in TAR and to assess their effectiveness.Methods:We collected data on domestic dog registration and deworming and stray dog sheltering in 74 counties/districts in the TAR from 2017 to 2019.Fecal samples from domestic dogs were collected from randomly selected towns to determine Echinococcus infection in dogs using coproantigen ELISA.We analyzed the data to compare the canine rate of infection between 2016 and 2019.The data analysis was performed by SPSS statistical to compare dog infection rate in 2016 and 2019 by chi-square test,and ArcGIS was used for mapping.Results:From 2017 to 2019,84 stray dog shelters were built in TAR,and accumulatively 446,660 stray or infected dogs were arrested,sheltered,or disposed of.The number of domestic dogs went downward,with an increased registration management rate of 78.4%(2017),88.8%(2018),and 99.0%(2019).Dogs were dewormed 5 times in 2017,12 times in 2018,and 12 times in 2019.The dog infection rate was 1.7%(252/14,584)in 2019,significantly lower than 7.3%(552/7564)from the survey of echinococcosis prevalence in Tibet in 2016(P<0.05).Conclusion:Between 2017 and 2019,the number of stray dogs and infection rate of Echinococcus spp.in domestic dogs decreased significantly,indicating that dogs were effectively controlled as a source of infection in TAR and reflecting a significant decrease in the risk of echinococcosis transmission. | Liying Wang Quzhen Gongsang Huasheng Pang Min Qin Ying Wang Jingzhong Li Roger Frutos Laurent Gavotte | 2022 | Infectious Diseases of Poverty2022，11，3： | 0 |
| 12 | Investigation on the Management for Patients with Echinococcosis Treated with Albendazole-Three PLADs,China,2019显示文摘Summary What is already known about this topic?In China,patients with echinococcosis receive complimentary healthcare services,such as medical treatment,diagnostic examinations,and follow-up care.Despite this,no studies have been conducted to assess the quality of patient management to date.What is added by this report?This study reviewed the medical records of 899 patients who underwent albendazole treatment across 10 endemic counties.Out of 634 evaluable patient files,the proportion of patients with a ratio of actual followup and reexamination times to theoretical follow-up and reexamination times≥0.8 were both low(21.92%and 23.19%,respectively).What are the implications for public health practices?This study identified weaknesses and specific issues in patient management and proposed feasible recommendations to enhance patient file documentation,follow-up,and reexamination. | Min Qin Liying Wang Ying Wang Xu Wang Jiaxi Lei Xixi Cheng Yu Feng Yanyan Hou Qian Wang Chuizhao Xue Laurent Gavotte Roger Frutos | 2023 | China CDC weekly2023，5，20： | 0 |
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