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| 1 | The Chinese Hα Solar Explorer(CHASE) mission: An overview显示文摘The Chinese Hα Solar Explorer(CHASE), dubbed “Xihe”—Goddess of the Sun, was launched on October 14, 2021 as the first solar space mission of China National Space Administration(CNSA). The CHASE mission is designed to test a newly developed satellite platform and to acquire the spectroscopic observations in the Hα waveband. The Hα Imaging Spectrograph(HIS)is the scientific payload of the CHASE satellite. It consists of two observational modes: raster scanning mode and continuum imaging mode. The raster scanning mode obtains full-Sun or region-of-interest spectral images from 6559.7 to 6565.9 ? and from 6567.8 to 6570.6 ? with 0.024 ? pixel spectral resolution and 1 min temporal resolution. The continuum imaging mode obtains photospheric images in continuum around 6689 ? with the full width at half maximum of 13.4 ?. The CHASE mission will advance our understanding of the dynamics of solar activity in the photosphere and chromosphere. In this paper, we present an overview of the CHASE mission including the scientific objectives, HIS instrument overview, data calibration flow, and first results of on-orbit observations. | Chuan Li Cheng Fang Zhen Li MingDe Ding PengFei Chen Ye Qiu Wei You Yuan Yuan MinJie An HongJiang Tao XianSheng Li Zhe Chen Qiang Liu Gui Mei Liang Yang Wei Zhang WeiQiang Cheng JianXin Chen ChangYa Chen Qiang Gu QingLong Huang MingXing Liu ChengShan Han HongWei Xin ChangZheng Chen YiWei Ni WenBo Wang ShiHao Rao HaiTang Li Xi Lu Wei Wang Jun Lin YiXian Jiang LingJie Meng Jian Zhao | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，8： | 7 |
| 2 | COVID-19 Cases Spread Through the K350 Train-Jilin and Heilongjiang Provinces,China,January 2021显示文摘As of 16∶00 on January 13,2021,95 positive cases of coronavirus disease 2019(COVID-19)were reported in Suihua City of Heilongjiang Province and an additional 35 cases have been linked across 7 cities in 3 provinces:Qiqihar City(7 cases),Mudanjiang City(4 cases),Harbin City(3 cases),and Yichun City(1 case)of Heilongjiang Province;Changchun City(9 cases)and Tonghua City(6 cases)of Jilin Province;and Weihai City of Shandong Province(1 case). | Lei Zhou Laishun Yao Peter Hao Chao Li Qinglong Zhao Huiling Dong Jinhua Dou Shengnan Wang George F.Gao Qun Li Biao Huang | 2021 | China CDC weekly2021，3，8： | 5 |
| 3 | Effectiveness of Interventions to Control Transmission of Reemergent Cases of COVID-19--Jilin Province,China,2020显示文摘What is already known about this topic?COVID-19 has a high transmissibility calculated by mathematical model.The dynamics of the disease and the effectiveness of intervention to control the transmission remain unclear in Jilin Province,China.What is added by this report?This is the first study to report the dynamic characteristics and to quantify the effectiveness of interventions implemented in the second outbreak of COVID-19 in Jilin Province,China.The effective reproduction number of the disease before and after May 10 was 4.00 and p<0.01,respectively.The combined interventions reduced the transmissibility of COVID-19 by 99% and the number of cases by 98.36%.What are the implications for public health practice?The findings of this study would add data on the transmission of COVID-19 and provide evidence to prepare the second outbreak transmission of the disease in other areas of China even in many other countries. | Qinglong Zhao Meng Yang Yao Wang Laishun Yao Jianguo Qiao Zhiyong Cheng Hanyin Liu Xingchun Liu Yuanzhao Zhu Zeyu Zhao Jia Rui Tianmu Chen | 2020 | China CDC weekly2020，2，34： | 2 |
| 4 | Oroxylin A inhibits matrix metalloproteinase-2/9 expression and activation by up-regulating tissue inhibitor of metalloproteinase-2 and suppressing the ERK1/2 signaling pathway显示文摘 | Zhijian Lu Na Lu Chenglin Li Fanni Li Kai Zhao Biqi Lin Qinglong Guo | 2012 | Toxicology Letters2012，，3： | 2 |
| 5 | How delaying post-silking senescence in lower leaves of maize plants increases carbon and nitrogen accumulation and grain yield显示文摘Planting maize at high densities leads to early leaf senescence,and the resulting reduction in the number of lower leaves affects the plant’s root function and lowers its grain yield.However,the nature of the process by which lower leaf senescence affects biomass accumulation and grain yield formation in maize is not clear.This study aimed to shed light on how these factors are related by investigating the effects of the plant growth regulator 6-benzyladenine(6-BA)on the senescence of lower leaves of maize plants.In two maize cultivars planted at densities of 67,500(low density,LD)and 90,000(high density,HD)plants ha^(-1),plants treated with 6-BA maintained a high green leaf area index(LAI)longer than control(CK)plants,enabling them to maintain a higher photosynthetic rate for a longer period of time and produce more biomass before reaching physiological maturity.Spraying the lower leaves of maize plants with a 6-BA solution increased the distribution of;C-photosynthates to their roots,lower leaves and bracts,a result that can be ascribed to a decreased retention of;C-photosynthates in the stem and grain.In both seasons of the experiment,maize plants treated with 6-BA accumulated more N in grain and maintained a higher N content in roots and leaves,especially in lower leaves,than CK.Increased C assimilation in the lower leaves may explain why N uptake in plants subjected to the 6-BA treatment exceeded that in CK plants and why both photosynthesis rate and dry matter accumulation were maintained throughout grain filling.Our results suggest that a suitable distribution of C and N in leaves post-silking may maintain plant root function,increase N use efficiency,maximize the duration of high LAI,and increase grain yield. | Rongfa Li Dandan Hu Hao Ren Qinglong Yang Shuting Dong Jiwang Zhang Bin Zhao Peng Liu | 2022 | The Crop Journal2022，10，3： | 2 |
| 6 | Enzyme-Triggered Fluorescence Turn-on: A Probe for Specifically Imaging Ovarian-Cancer-Related γ-Glutamyltranspeptidase显示文摘 | Jie Tian Qinglong Yan Ying Zhu Jichao Zhang Jiao Li Ben Shi Ge Xu Chunhai Fan Chunchang Zhao | 2017 | Chinese Journal of Chemistry2017，35，11： | 2 |
| 7 | Promoted catalytic performances of highly dispersed V-doped SBA-16 catalysts for oxidative dehydrogenation of ethane to ethylene显示文摘V-doped SBA-16 catalysts(V-SBA-16) with 3D nanocage mesopores have been successfully synthesized by a modified one-pot method under weak acid condition.The obtained materials were characterized by means of small angle XRD,N_2 adsorption–desorption,TEM,UV–Vis and UV-Raman spectroscopy.These characterization results indicated that well-order mesoporous structures were maintained even at higher vanadium loadings and high concentration of VOx species were incorporated into the framework of SBA-16 support.The catalytic performances of V-SBA-16,V/SBA-16 and V/Si O_2 catalysts were comparatively investigated for the oxidative dehydrogenation of ethane to ethylene.The highest selectivity to ethylene of 63.3% and ethylene yield of 25.6% were obtained over 1.0V-SBA-16 catalyst.The superior catalytic performance of V-SBA-16 catalysts could be attributed to the presence of isolated framework VO x species,the unique structure of SBA-16 support and weak acidity.Moreover,V/Si O_2 catalyst exhibited relatively poor catalytic activity duo to the formation of V_2O_5 nanoparticles on the surface of Si O_2 support and the low dispersion of VO x species.These results indicated that the catalytic performances of the studied catalysts were strongly dependent on the vanadium loading,the nature and neighboring environment of VO x species and the structure of support. | Lian Kong Jianmei Li Qinglong Liu Zhen Zhao Qianyao Sun Jian Liu Yuechang Wei | 2016 | Journal of Energy Chemistry2016，25，4： | 1 |
| 8 | Systematic investiga- tion on shape stability of high-efficiency SEBS/paraffin form-stable phase change materials显示文摘 | Zhang Qinglong Zhao Yiqing Feng Jiachun | 2013 | Solar Energy Materials & Solar Cells2013，118，： | 1 |
| 9 | Comparison of heavy metal accumulation by a bloom-forming cyanobacterium,Microcystis aeruginosa显示文摘Microcystis aeruginosa is the dominant species during cyanobacterial blooms in freshwater lakes.In the present study,we compared the bioaccumulation characteristics of cadmium(Cd) and zinc(Zn) in Microcystis cells.In short-term uptake tests,a rapid sorption of Cd and Zn occurred in the first few minutes,with a subsequent slower internalization process.No obvious difference was observed between Zn and Cd in terms of their short-term uptake kinetics.In efflux experiments,elimination of Zn from the cells was faster than that of Cd.In the 72-h exposure tests,the intracellular Cd concentrations increased with exposure time whereas the intracellular Zn concentrations always reached a plateau.The cellular Cd showed greater variation than the cellular Zn at various free Cd 2+ or Zn 2+ concentrations.The differences in Cd and Zn accumulation and elimination indicated that Microcystis cells had a higher bioaccumulation capacity for Cd than for Zn.In field studies,the bioconcentration factor(BCF) of Cd in lake-harvested Microcystis was more than 10 times higher than those of other metals.The results of the present study strongly suggested that the bloom-forming Microcystis may affect the Cd transportation and biogeochemical cycling in eutrophic freshwater ecosystems. | ZENG Jin ZHAO DaYong JI YongBan WU QingLong | 2012 | Chinese Science Bulletin2012，57，28： | 1 |
| 10 | Selective oxidation of ethane to aldehydes over SBA-15 supported molybdenum catalyst显示文摘SBA-15 supported Mo catalysts(Moy/SBA-15) were prepared by an ultrasonic assisted incipient-wetness impregnation method. The physical and chemical properties of the catalysts were characterized by means of N2-adsorption-desorption, XRD, TEM, UV-Vis, Raman, XANES and H2-TPR. The results showed that a trace amount of MoO3 was produced on high Mo content samples. Turn-over frequency(TOF) and product selectivity are dependent on the molybdenum content. Both Mo0.75/SBA-15 and Mo1.75/SBA-15 catalysts give the higher catalytic activity and the selectivity to the total aldehydes for the selective oxidation of C2H6. At the reaction temperature of 625℃, the maximum yield of aldehydes reached 4.2% over Mo0.75/SBA-15 catalyst. The improvement of the activity and selectivity was related with the state of MoOx species. | Jianmei Li Jian Liu Liwei Ren Qinglong Liu Zhen Zhao Yongsheng Chen Pengyu Zhu Yuechang Wei Aijun Duan Guiyuan Jiang | 2014 | Journal of Energy Chemistry2014，23，5： | 1 |
| 11 | Ambient Temperature and Years of Life Lost:A National Study in China显示文摘Although numerous studies have investigated premature deaths attributable to temperature,effects of temperature on years of life lost(YLL)remain unclear.We estimated the relationship between temperatures and YLL,and quantified the YLL per death caused by temperature in China.We collected daily meteorological and mortality data,and calculated the daily YLL values for 364 locations(2013–2017 in Yunnan,Guangdong,Hunan,Zhejiang,and Jilin provinces,and 2006–2011 in other locations)in China.A time-series design with a distributed lag nonlinear model was first employed to estimate the location-specific associations between temperature and YLL rates(YLL/100,000 population),and a multivariate meta-analysis model was used to pool location-specific associations.Then,YLL per death caused by temperatures was calculated.The temperature and YLL rates consistently showed U-shaped associations.A mean of 1.02(95%confidence interval:0.67,1.37)YLL per death was attributable to temperature.Cold temperature caused 0.98 YLL per death with most from moderate cold(0.84).The mean YLL per death was higher in those with cardiovascular diseases(1.14),males(1.15),younger age categories(1.31 in people aged 65–74 years),and in central China(1.34)than in those with respiratory diseases(0.47),females(0.87),older people(0.85 in people R75 years old),and northern China(0.64)or southern China(1.19).The mortality burden was modified by annual temperature and temperature variability,relative humidity,latitude,longitude,altitude,education attainment,and central heating use.Temperatures caused substantial YLL per death in China,which was modified by demographic and regional characteristics. | Tao Liu Chunliang Zhou Haoming Zhang Biao Huang Yanjun Xu Lifeng Lin Lijun Wang Ruying Hu Zhulin Hou Yize Xiao Junhua Li Xiaojun Xu Donghui Jin Mingfang Qin Qinglong Zhao Weiwei Gong Peng Yin Yiqing Xu Jianxiong Hu Jianpeng Xiao Weilin Zeng Xing Li Siqi Chen Lingchuan Guo Zuhua Rong Yonghui Zhang Cunrui Huang Yaodong Du Yuming Guo Shannon Rutherford Min Yu Maigeng Zhou Wenjun Ma | 2021 | The Innovation2021，2，1： | 1 |
| 12 | Transmissibility of tuberculosis among students and non-students:an occupational-specific mathematical modelling显示文摘Background: Recently, despite the steady decline in the tuberculosis (TB) epidemic globally, school TB outbreaks have been frequently reported in China. This study aimed to quantify the transmissibility ofMycobacterium tuberculosis (MTB) among students and non-students using a mathematical model to determine characteristics of TB transmission.Methods: We constructed a dataset of reported TB cases from four regions (Jilin Province, Xiamen City, Chuxiong Prefecture, and Wuhan City) in China from 2005 to 2019. We classified the population and the reported cases under student and non-student groups, and developed two mathematical models [nonseasonal model (Model A) and seasonal model (Model B)] based on the natural history and transmission features of TB. The effective reproduction number (R(eff)) of TB between groups were calculated using the collected data.Results: During the study period, data on 456,423 TB cases were collected from four regions: students accounted for 6.1% of cases. The goodness-of-fit analysis showed that Model A had a better fitting effect (P < 0.001). The average R_(eff) of TB estimated from Model A was 1.68 [interquartile range (IQR): 1.20–1.96] in Chuxiong Prefecture, 1.67 (IQR: 1.40–1.93) in Xiamen City, 1.75 (IQR: 1.37–2.02) in Jilin Province, and 1.79 (IQR: 1.56–2.02) in Wuhan City. The average R_(eff) of TB in the non-student population was 23.30 times (1.65/0.07) higher than that in the student population.Conclusions: The transmissibility of MTB remains high in the non-student population of the areas studied, which is still dominant in the spread of TB. TB transmissibility from the non-student-to-student-population had a strong influence on students. Specific interventions, such as TB screening, should be applied rigorously to control and to prevent TB transmission among students. | Qiuping Chen Shanshan Yu Jia Rui Yichao Guo Shiting Yang Guzainuer Abudurusuli Zimei Yang Chan Liu Li Luo Mingzhai Wang Zhao Lei Qinglong Zhao Laurent Gavotte Yan Niu Roger Frutos Tianmu Chen | 2022 | Infectious Diseases of Poverty2022，11，6： | 0 |
| 13 | QUANTITATIVE ANALYSIS OF RELATIONSHIP BETWEEN ARMILLARIA ROOT ROT AND SITE FACTORS IN PINUS RADIATA PLANTATIONS显示文摘Incidence of Armillaria infection was quantified based on site factors in New Zealand Pinus radiata plantations.A linear multiple regression model was derived to predict infection levels of Armillaria root rot.Factors positivily associated with the infection were:previous vegetation(native bush,pine);soil type(pumice);landform (valley,gully,flat)and the interaction between them.This model could assist in management planning with regard to the predisposition of particular stand to Armillaria infection.Keywods:Armillaria root rot,Disease incidence,Site factors,Quantification,Pinus radiata. | Shu Qinglong He Min Song Shumei Zhao Weizhong(Department of Forestry,Anhui Agricultural University,Hefei 230036)(School of Forestry,University of Canterbury,Christchurch,New Zealand)(Shanxi Agricultura1 University,Taigu,shanxi.) | 1995 | 生物数学学报1995，10，3： | 0 |
| 14 | Rapid screening of SARS-CoV-2 inhibitors via ratiometric fluorescence of RBD–ACE2 complexes in living cells by competitive binding显示文摘To the Editor:The current coronavirus disease-19(COVID-19)pandemic spurs the development of antiviral drugs for SARS-CoV-2,as the number of patients with viral infections continues to rise globally in the context of widespread vaccination.Targeting the interaction between the receptor binding domain(RBD)of SARS-CoV-2 spike protein and the host cell ACE2 is a promising therapeutic strategy to effectively inhibit viral entry. | Lu Miao Wei Zhou Chunyu Yan Yuebin Zhang Qinglong Qiao Xuelian Zhou Yingzhu Chen Guangying Wang Zhendong Guo Jun Liu Hailong Piao Xia Pan Mengxue Yan Weijie Zhao Guohui Li Yueqing Li Zhaochao Xu | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 0 |
| 15 | Model Averaging Estimation for Varying-Coefficient Single-Index Models显示文摘The varying-coefficient single-index model(VCSIM)is widely used in economics,statistics and biology.A model averaging method for VCSIM based on a Mallows-type criterion is proposed to improve prodictive capacity,which allows the number of candidate models to diverge with sample size.Under model misspecification,the asymptotic optimality is derived in the sense of achieving the lowest possible squared errors.The authors compare the proposed model averaging method with several other classical model selection methods by simulations and the corresponding results show that the model averaging estimation has a outstanding performance.The authors also apply the method to a real dataset. | LIU Yue ZOU Jiahui ZHAO Shangwei YANG Qinglong | 2022 | Journal of Systems Science & Complexity2022，35，1： | 0 |
| 16 | Aptamer based fluorescent probe for serum HER2-ECD detection: The clinical utility in breast cancer显示文摘The transmembrane protein HER2 is overexpressed in approximately 30% of breast cancer patients.HER2-positive breast cancers tend to spread more aggressively, which result in increased mortality in women. Nowadays, the real-time monitoring of HER2 status is important in clinical diagnosis and treatment for HER2-positive patients. Although IHC and FISH assay are standard methods to evaluate the tissue HER2 status, both approaches which required high quality tissue samples and are not suitable for monitoring the status of HER2 in real time. Since extracellular domain(ECD) of the HER2 receptor can be shed into the circulation, the serum test of HER2 ECD has been developed as an additional approach to probe HER2 overexpression. The serum test will be able to monitor the dynamic changes of HER2 status.In this paper, we detected serum HER2 ECD using Cy5-labeled HB5 aptamer as a result of its specific binding ability to HER2 ECD. This aptamer-based fluorescent probe is easily synthesized and modified and as sensitive as anti-HER2 antibodies. We believe that Cy5-HB5 may have application potentials in serum HER2 test for clinical utility of breast cancer, such as recurrence and metastases. | Meiling Wang Dongfang Yue Qinglong Qiao Lu Miao Haidong Zhao Zhaochao Xu | 2018 | Chinese Chemical Letters2018，29，5： | 0 |
| 17 | The substitution V379I in PA protein attenuates the pathogenicity of influenza A(H1N1)pdm09 viruses in mice显示文摘Dear Editor,Since August 2010,the world was in the post-pandemic period and the influenza A(H1N1)pdm09(pdmH1N1)virus co-circulated with H3N2 and B virus seasonally(WHO,2010).The continuous surveillance on the pdmH1N1 virus in the post-pandemic period was recommended by WHO.In order to detect unusual events that might indicate a shift in severity disease,or emergence of a new virus,we collected a total of 312 throat swabs of laboratory-confirmed pdmHlNl patients from Hunan and Jilin provinces in | Yongkun Chen Wenfei Zhu Tian Bai Xiaohui Zou Siyu Zhang Yan Sun Xiyan Li XingyYu Xiang Qinglong Zhao Chaoyang Huang Tao Chen Dayan Wang Yuelong Shu | 2017 | Science China(Life Sciences)2017，60，9： | 0 |
| 18 | Multiple characteristic alterations and available therapeutic strategies of cellular senescence显示文摘Given its state of stable proliferative inhibition,cellular senescence is primarily depicted as a critical mechanism by which organisms delay the progression of carcinogenesis.Cells undergoing senescence are often associated with the alteration of a series of specific features and functions,such as metabolic shifts,stemness induction,and microenvironment remodeling.However,recent research has revealed more complexity associated with senescence,including adverse effects on both physiological and pathological processes.How organisms evade these harmful consequences and survive has become an urgent research issue.Several therapeutic strategies targeting senescence,including senolytics,senomorphics,immunotherapy,and function restoration,have achieved initial success in certain scenarios.In this review,we describe in detail the characteristic changes associated with cellular senescence and summarize currently available countermeasures. | YUNZI ZHAO HUI LI QINGLONG GUO HUI HUI | 2023 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2023，24，2： | 0 |
| 19 | Genome-Wide Identification,Expression Profiling and Protein-Protein Interaction Properties of the BEL-Like Homeodomain Gene Family in Apple显示文摘BEL1-like homeodomain(BLH)family proteins are homeodomain transcription factors,which are found ubiquitously in plants and play important roles in regulating meristem and flower development.Although BLH proteins have been reported in some plant species,there is very little information available for plants in the Malus genus(e.g.,apple tree:Malus domestica).In the present study,we identified 19 apple MdBLH genes.Phylogenetic analysis revealed that the MdBLH genes could be divided into five groups.Analysis of gene structure showed that MdBLH gene has four exons,and the third exon was 61 bp in length.Chromosomal location analysis suggested that the MdBLH genes are not distributed uniformly on 12 chromosomes.Eleven MdBLH genes were cloned by RT-PCR,and their expression patterns were also determined.Among them,the expression levels of MdBLH4.1 and MdBLH9.1 could be induced by sodium chloride stress,while the expression levels of MdATH1.1,MdBLH8.1,MdBLH8.3,and MdBLH11.1 were down-regulated by such stress.Transcriptional levels of MdATH1.1 and MdBLH7.2 were down-regulated by mannitol stress.The result of yeast two-hybrid experiment showed that MdBEL1.1 interacted with apple ovate family proteins 6(MdOFP6),and MdBLH3.1 interacted with the MdOFP4,MdOFP6,MdOFP13,and MdOFP16 proteins.Our results provide a strong theoretical basis and a valuable reference for analyzing of the biological functions of MdBLH proteins as transcription factors in apple growth,development,and stress and also for the construction of regulatory networks. | Huifeng Li Qiang Zhao Hai Wang Qinglong Dong Yi Xu | 2022 | Phyton-International Journal of Experimental Botany2022，91，2： | 0 |
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