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| 1 | Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells显示文摘外长的 dopaminergic 神经原(DA 神经原) 的移植是为治疗 Parkinson 的疾病(PD ) 的一条有希望的途径。然而,主要跌倒块是施主 DA 神经原的可靠来源的缺乏。这里,我们证明五 transcriptional 因素 Mash1, Ngn2, Sox2, Nurr1,和 Pitx3 的联合直接并且有效地装改编人成纤维细胞进 DA 像神经原的房间。为为 DA 神经原的各种各样的标记积极的染色的 reprogrammed 房间。他们也显示出典型 DA 举起和生产性质。而且,他们展出了 DA 神经原特定的 electrophysiological 侧面。最后,他们在一个老鼠 PD 模型提供了征兆的地势。因此,我们的直接 reprogrammed DA 像神经原的房间是为 PD 的房间代替治疗的有希望的来源。 | Xinjian Liu Fang Li Elizabeth A Stubblefield Barbara Blanchard Toni L Richards Gaynor A Larson Yujun He Qian Huang Aik-Choon Tan Dabing Zhang Timothy A Benke John R Sladek Nancy R Zahniser Chuan-Yuan Li | 2012 | Cell Research2012，22，2： | 14 |
| 2 | RNA interference directed against viral and cellular targets inhibits human immu-nodeficiency Virus Type 1 replication 显示文摘 | SURABHI R M GAYNOR R B | 2002 | J Virol2002，76，12： | 1 |
| 3 | Therapeutic potential of inhibition of the NF-kB pathway in the treatment of inflammatory and cancer显示文摘 | YAMAMOTO Y GAYNOR R B | 2001 | J Clin Invest2001，107，2： | 1 |
| 4 | Day length, latitude and behavioural (in) flexibility in baboons ( Papio cyno- cephalus ursinus) 显示文摘 | Hill R A Barret L Gaynor D | 2003 | Behav Ecol Sociobiol2003，53，5： | 1 |
| 5 | Comparison of astandard regmen ( CHOP ) with three intensive chemothapy regimens tor advanced non- Hodgkin+ slymphoma显示文摘 | Fishex R Gaynor ER Dahlberg S | 1999 | N Earl J Med1999，28，： | 1 |
| 6 | Localiza-tion of the gene-encoding upstream stimulatory factor(USF)tohuman chromosome 1q22-q23显示文摘 | SHIEH B H SPARKES R S GAYNOR R B | 1993 | Genomics1993，16，： | 1 |
| 7 | Circulating endothelium as indication of vascular injury显示文摘 | Bouvier CA Gaynor E Cintron J R | 1970 | Thromb Diath Haemorrh1970，40，6： | 1 |
| 8 | A phase Ⅱ study of 5-Fu and LV plus open label Rofecoxib in patients with metastatic colorectal cancer 显示文摘 | Becerra CR Frenkel EP Gaynor R | 2002 | Proc Am Soc Clin Oncol2002，21，10： | 1 |
| 9 | Milk Fat Depression,the Glucogenic Theory, and Trans-C18: 1 Fatty Acidsl显示文摘 | Gaynor P J Waldo D R Capuco A V | 1995 | Journal of Dairy Science1995，78，9： | 1 |
| 10 | Comparison of a standard regimen (CHOP) with three intensive chemother- apy regimens for advanced non-HodgkinYs lymphoma 显示文摘 | Fisher R I Gaynor N R Dahlberg S | 1993 | N Engl J Med1993，328，14： | 1 |
| 11 | Inflam- mation of atrium after cardiac surgery is associated with inhomogeneity of atrial conduction and atrial fi- brillation显示文摘 | Ishii Y Schuessler R B Gaynor S L | 2005 | Circulation2005，111，22： | 1 |
| 12 | Comparison of a standard regimen (CHOP)with three intensive chemotherapy regimens for advanced non-Hodgkin' s lymphoma 显示文摘 | Fisher R I Gaynor E R Dahlberg S | 1993 | N Engl J Med1993，328，2： | 1 |
| 13 | International foodbome outbreak of Shigella sonrtei infection in airline passengers显示文摘 | Gaynor K Park SY Kanenaka R | 2009 | Epidemiol Infect2009，137，3： | 1 |
| 14 | Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma显示文摘 | Fisher R I Gaynor E R Dahlerg S | 1993 | N Engl J Med1993，328，： | 1 |
| 15 | Abscisic acid content of Citrus flavedo in relation to colour development显示文摘 | Gaynor R Richardson Cowan A K | 1995 | J Hortic Sci1995，70，5： | 1 |
| 16 | IkappaB kinases:key regulators of the NF-kappaB pathway显示文摘 | Yamamoto Y Gaynor R B | 2004 | Trends Biochem Sci2004，29，2： | 1 |
| 17 | Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advaneed non-Hodgkin's lemphoma 显示文摘 | FISHER R I GAYNOR E R DAHLBERG S | 1993 | N Engl J Med1993，328，14： | 1 |
| 18 | RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type 1replication显示文摘 | Surabhi R M Gaynor R B | 2002 | J Virol2002，76，12： | 1 |
| 19 | Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin's lymphoma 显示文摘 | Fisher R I Gaynor N R Dahlberg S | 1993 | N Engl J Med1993，328，14： | 1 |
| 20 | Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-hodgkin's lymphoma 显示文摘 | Fisher R I Gaynor E R Dahlberg S | 1993 | N Engl J Med1993，328，14： | 1 |
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