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12篇 您的检索式:作者名="Geoffrey Morgan"
    题名 作者 年代 出处 被引量
1Endoscopic Retrograde Cholangiopancreatography with Single-Balloon Enteroscopy Is Feasible in Patients with a Prior Roux-en-Y Anastomosis显示文摘Evan S. Dellon Geoffrey P. Kohn Douglas R. Morgan Ian S. Grimm 2009Digestive Diseases and Sciences2009,,8:2
2Early cholecystectomy and ERCP are associated with reduced readmissions for acute biliary pancreatitis: a nationwide, population-based study显示文摘Geoffrey C. Nguyen Morgan Rosenberg Rachel Y. Chong Christopher A. Chong 2012Gastrointestinal Endoscopy2012,,1:2
3Reflections on the Catastrophic 2019-2020 Australian Bushfires显示文摘While fire is an inherent part of the Australian landscape,the bushfires that occurred in eastern Australia from September 2019 to early February 2020 were unprecedented(Figure 1).Bushfires across the nation burned more than 12.6 million hectares(an area slightly bigger than Belgium,Denmark,and the Netherlands combined),emitted about 430 tonnes of carbon dioxide into the atmosphere(about three-quarters of the country's total annual carbon dioxide emissions),directly caused at least 33 deaths and over one billion animals were killed(https://www.abc.net.au/news/science/2020-03-05/bushfire-crisis-five-big-numbers/12007716).Bin Jalaludin Fay Johnston Sotiris Vardoulakis Geoffrey Morgan 2020The Innovation2020,1,1:1
4Structural studies on Plasmodium vivax merozoite surface protein-1显示文摘Jeffrey J. Babon William D. Morgan Geoffrey Kelly John F. Eccleston James Feeney Anthony A. Holder 2007Molecular & Biochemical Parasitology2007,,1:1
5Evaluation of magnetic resonance diffusion and spectroscopy measurements as predictive biomarkers in stage 1 cervical cancer显示文摘Geoffrey S. Payne Maria Schmidt Veronica A. Morgan Sharon Giles Jane Bridges Thomas Ind Nandita M. deSouza 2009Gynecologic Oncology2009,,:1
6Endoscopic Retrograde Cholangiopancreatography with Single-Balloon Enteroscopy Is Feasible in Patients with a Prior Roux-en-Y Anastomosis显示文摘Evan S. Dellon Geoffrey P. Kohn Douglas R. Morgan Ian S. Grimm 2009Digestive Diseases and Sciences2009,,8:1
7Early cholecystectomy and ERCP are associated with reduced readmissions for acute bili- ary pancreatitis: a nationwide, population-based study 显示文摘Geoffrey CN Morgan R Rachel YC 2012Gastrointest Endosc2012,75,1:1
8Long-term omega-3 polyunsaturated fatty acid supplementation reduces the recurrence of persistent atrial fibrillation after electrical cardioversion显示文摘Saurabh Kumar Fiona Sutherland Joseph B. Morton Geoffrey Lee John Morgan James Wong David E. Eccleston John Voukelatos Manohar L. Garg Paul B. Sparks 2012Heart Rhythm2012,,:1
9Endoscopic Retrograde Cholangiopancreatography with Single-Balloon Enteroscopy Is Feasible in Patients with a Prior Roux-en-Y Anastomosis显示文摘Evan S. Dellon Geoffrey P. Kohn Douglas R. Morgan Ian S. Grimm 2009Digestive Diseases and Sciences2009,,8:1
10Early cholecystectomy and ERCP are associated with reduced readmissions for acute biliary pancreatitis:a nationwide,population-based study显示文摘Geoffrey CN Morgan R Rachel YC 2012Gastrointest Endosc2012,75,1:1
11CTLA4 protects against maladaptive cytotoxicity during the differentiation of effector and follicular CD4^(+)T cells显示文摘As chronic antigenic stimulation from infection and autoimmunity is a feature of primary antibody deficiency(PAD),analysis of affected patients could yield insights into T-cell differentiation and explain how environmental exposures modify clinical phenotypes conferred by single-gene defects.CD57 marks dysfunctional T cells that have differentiated after antigenic stimulation.Indeed,while circulating CD57^(+)CD4^(+)T cells are normally rare,we found that they are increased in patients with PAD and markedly increased with CTLA4 haploinsufficiency or blockade.We performed single-cell RNA-seq analysis of matched CD57^(+)CD4^(+)T cells from blood and tonsil samples.Circulating CD57^(+)CD4^(+)T cells(CD4cyt)exhibited a cytotoxic transcriptome similar to that of CD8^(+)effector cells,could kill B cells,and inhibited B-cell responses.CTLA4 restrained the formation of CD4cyt.While CD57 also marked an abundant subset of follicular helper T cells,which is consistent with their antigen-driven differentiation,this subset had a preexhaustion transcriptomic signature marked by TCF7,TOX,and ID3 expression and constitutive expression of CTLA4 and did not become cytotoxic even after CTLA4 inhibition.Thus,CD57^(+)CD4^(+)T-cell cytotoxicity and exhaustion phenotypes are compartmentalised between blood and germinal centers.CTLA4 is a key modifier of CD4^(+)T-cell cytotoxicity,and the pathological CD4cyt phenotype is accentuated by infection.Yuwei Hao Bahar Miraghazadeh Rochna Chand Ainsley R.Davies Chelisa Cardinez Kristy Kwong Morgan B.Downes Rebecca A.Sweet Pablo F.Cañete Lloyd J.D’Orsogna David A.Fulcher Sharon Choo Desmond Yip Geoffrey Peters Sonia Yip Matthew J.Witney Maxim Nekrasov Zhi-Ping Feng David C.Tscharke Carola G.Vinuesa Matthew C.Cook 2023Cellular & Molecular Immunology2023,20,7:0
12母亲颗粒物空气污染暴露与足月出生体重:效应与异质性的多国评估显示文摘[背景]越来越多的证据显示,母亲空气污染暴露与对胎儿生长的不良影响之间存在关联;但是,现有的文献并不一致。[目的]研究9个国家14个中心的数据,量化母亲颗粒物空气污染暴露与足月出生体重和低出生体重(LBW)之间的关联,并探讨此关联中地点特征和暴露评估方法对中心之间异质性的影响。[方法]空气污染与妊娠结局国际合作(ICAPPO)的各中心采用共同的分析方案,对PM10和PM2.5(颗粒物≤10和2.5μm)与足月LBW和连续出生体重进行效应评估。采用meta分析将各个中心(~300万例出生)的效应评估结合起来,并采用meta回归分析在报告的效应评估中,中心特征和暴露评估方法对中心之间异质性的影响。[结果]随机效应meta分析显示,调整母亲的社会经济地位后,在整个妊娠期间,足月LBW与PM10[比值比(OR)=1.03;95%CI:1.01~1.05]和PM2.5[OR=1.10;95%CI:1.03~1.18]每增加10μg/m3呈正相关。在充分调整随机效应的meta分析中,作为一个连续性的结果,PM10暴露每增加10μg/m3与足月出生体重呈负相关(-8.9g;95%CI:-13.2^-4.6 g)。meta回归分析显示,具有较高平均PM2.5水平和PM2.5∶PM10比率的中心,以及采用时间暴露评估(与时空相比)的中心,所报告的关联更强。[结论]在研究人群中,母亲颗粒物污染暴露与足月LBW相关联。有3个地点特征和暴露评估方法学方面的不同导致各个中心报告的关联的差异。Payam Dadvand Jennifer Parker Michelle L. Bell Matteo Bonzini Michael Brauer Lyndsey A. Darrow Ulrike Gehring Svetlana V. Glinianaia Nelson Gouveia Eun-hee Ha Jong Han Leem Edith H. van den Hooven Bin Jalaludin Bill M. Jesdale Johanna Lepeule Rachel Morello-Frosch Geoffrey G. Morgan Angela Cecilia Pesatori Frank H. Pierik Tanja Pless-Mulloli David Q. Rich Sheela Sathyanarayana Juhee Seo Rémy Slama Matthew Strickland Lillian Tamburic Daniel Wartenberg Mark J. Nieuwenhuijsen Tracey J. Woodruff 2013环境与职业医学2013,30,6:0
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