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| 1 | Development and evaluation of real-time polymerase chain reaction assays on whole blood and paraffin-embedded tissues for rapid diagnosis of human brucellosis显示文摘 | Mireille MK Pierre AZ George FA | 2007 | Diagnostic Microbiolo Infectious Dis2007，59，4： | 1 |
| 2 | The effects of total knee arthroplasty on physical functioning in the older population 显示文摘 | George LK Ruiz D Jr Sloan FA | 2008 | Arthritis Rheum2008，58，10： | 1 |
| 3 | Mechanisms and state of the art of transcranial magnetic stimulation显示文摘 | George MS Nahas Z Kozel FA | 2002 | JECT2002，18，3： | 1 |
| 4 | Diaphragmatic rupture: A complication of violent cough显示文摘 | George L Rehman SU Khan FA | 2000 | Chest2000，117，4： | 1 |
| 5 | Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyo- cytes 显示文摘 | George CH Higgs GV Lai FA | 2003 | Circulation Research2003，93，6： | 1 |
| 6 | Mechanisms and state of the art of transcranial magnetic stimulation显示文摘 | George MS Nahas Z Kozel FA | 2002 | J ECT2002，18，3： | 1 |
| 7 | Developing new anti-arrhythmics:clues from the molecular basis of cardiac ryanodine receptor(RyR2) Ca2+-release channel dysfunction显示文摘 | George CH Lai FA | 2007 | Curr Pharm Des2007，13，31： | 1 |
| 8 | A replication study of the neural correlates of deception显示文摘 | Kozel FA Padgett TM George MS | 2004 | Behav Neurosci2004，118，4： | 1 |
| 9 | Ryanodine receptor mutations associated with stress-induced ventricular tachycardia mediate increased calcium release in stimulated cardiomyocytes显示文摘 | George CH Higgs GV Lai FA | 2003 | Circ Res2003，93，6： | 1 |
| 10 | Computational model of chromosome aberration yield induced by high- and low-LET radiation exposures显示文摘 | PONOMAREV A L GEORGE K CUCINOTTA FA | 2012 | Radiat Res2012，177，6： | 1 |
| 11 | Mechanisms and the current state of transcranial magnetic stimulation 显示文摘 | George MS Nahas Z Kozel FA | 2003 | CNS Soectrums2003，8，7： | 1 |
| 12 | Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transition显示文摘 | Paul Roepman Andreas Schlicker Josep Tabernero Ian Majewski Sun Tian Victor Moreno Mireille H Snel Christine M Chresta Robert Rosenberg Ulrich Nitsche Teresa Macarulla Gabriel Capella Ramon Salazar George Orphanides Lodewyk FA Wessels Rene Bernards Iris M | 2013 | Int. J. Cancer2013，，3： | 1 |
| 13 | Diaphragmatic rupture:a complication of violent cough显示文摘 | George L R ehman SU Khan FA | 2000 | Chest2000，117，： | 1 |
| 14 | Synergistic antiangiogenic effects of stathmin inhibition and taxol exposure 显示文摘 | Sucharita JM Alexander B George FA | 2007 | Mol Cancer Res2007，5，8： | 1 |
| 15 | Synergistic antiangiogenic effects of stathmin inhibition and taxol exposure 显示文摘 | Sucbarita JM Alexander B George FA | 2007 | Mol Cancer Res2007，5，8： | 1 |
| 16 | Recent developments in β lactamases and extend spectrum β lactamases 显示文摘 | Joumana NS George FA | 2003 | BMJ2003，327，： | 1 |
| 17 | Mechanisms and state of the art of transcranial magnetic stimulation 显示文摘 | George MS Nahas Z Kozel FA | 2002 | J ECT2002，18，4： | 1 |
| 18 | Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transition显示文摘 | Paul Roepman Andreas Schlicker Josep Tabernero Ian Majewski Sun Tian Victor Moreno Mireille H Snel Christine M Chresta Robert Rosenberg Ulrich Nitsche Teresa Macarulla Gabriel Capella Ramon Salazar George Orphanides Lodewyk FA Wessels Rene Bernards Iris M | 2013 | Int J Cancer2013，，3： | 1 |
| 19 | Meta-analysis of left prefrontal repetitive transcranial magnetic stimulation to treat depression显示文摘 | Kozel FA George MS | 2002 | J Psychiatr Pract2002，8，： | 1 |
| 20 | Effects of Resistant Starch on Symptoms,Fecal Markers,and Gut Microbiota in Parkinson’s Disease—The RESISTA-PD Trial显示文摘The composition of the gut microbiota is linked to multiple diseases,including Parkinson’s disease(PD).Abundance of bacteria producing short-chain fatty acids(SCFAs)and fecal SCFA concentrations are reduced in PD.SCFAs exert various beneficial functions in humans.In the interventional,monocentric,open-label clinical trial “Effects of Resistant Starch on Bowel Habits,Short Chain Fatty Acids and Gut Microbiota in Parkinson’s Disease”(RESISTA-PD;ID:NCT02784145),we aimed at altering fecal SCFAs by an 8-week prebiotic intervention with resistant starch(RS).We enrolled 87 subjects in three study-arms:32 PD patients received RS(PD+RS),30 control subjects received RS,and 25 PD patients received solely dietary instructions.We performed paired-end 100 bp length metagenomic sequencing of fecal samples using the BGISEQ platform at an average of 9.9 GB.RS was well-tolerated.In the PD+RS group,fecal butyrate concentrations increased significantly,and fecal calprotectin concentrations dropped significantly after 8 weeks of RS intervention.Clinically,we observed a reduction in non-motor symptom load in the PD+RS group.The reference-based analysis of metagenomes highlighted stable alpha-diversity and beta-diversity across the three groups,including bacteria producing SCFAs.Reference-free analysis suggested punctual,yet pronounced differences in the metagenomic signature in the PD+RS group.RESISTA-PD highlights that a prebiotic treatment with RS is safe and well-tolerated in PD.The stable alpha-diversity and beta-diversity alongside altered fecal butyrate and calprotectin concentrations call for long-term studies,also investigating whether RS is able to modify the clinical course of PD. | Anouck Becker Georges Pierre Schmartz Laura Groger Nadja Grammes Valentina Galata Hannah Philippeit Jacqueline Weiland Nicole Ludwig Eckart Meese Sascha Tierling Jorn Walter Andreas Schwiertz Jorg Spiegel Gudrun Wagenpfeil Klaus Faßbender Andreas Keller Marcus M.Unger | 2022 | Genomics, Proteomics & Bioinformatics2022，20，2： | 0 |
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