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| 1 | Gastric per-oral endoscopic myotomy: Current status and future directions显示文摘Gastroparesis, or symptomatic delayed gastric emptying in the absence of mechanical obstruction, is a challenging and increasingly identified syndrome. Medical options are limited and the only medication approved by the Food and Drug Administration for treatment of gastroparesis is metoclopramide, although other agents are frequently used off label. With this caveat, first-line treatments for gastroparesis include dietary modifications, antiemetics and promotility agents, although these therapies are limited by suboptimal efficacy and significant medication side effects. Treatment of patients that fail first-line treatments represents a significant therapeutic challenge. Recent advances in endoscopic techniques have led to the development of a promising novel endoscopic therapy for gastroparesis via endoscopic pyloromyotomy, also referred to as gastric per-oral endoscopic myotomy or per-oral endoscopic pyloromyotomy. The aim of this article is to review the technical aspects of the per-oral endoscopic myotomy procedure for the treatment of gastroparesis, provide an overview of the currently published literature, and outline potential next directions for the field. | Alexander Podboy Joo Ha Hwang Linda A Nguyen Patricia Garcia Thomas A Zikos Afrin Kamal George Triadafilopoulos John O Clarke | 2019 | World Journal of Gastroenterology2019，25，21： | 3 |
| 2 | 含高钙和维生素D的强化奶能有效提高健康的绝经后的中国女性体内的维生素D水平并减少骨吸收显示文摘目的钙摄入水平低以及体内维生素D不足是导致亚洲女性罹患骨质疏松的危险因素。此项研究的目的是评估高钙维生素D强化牛奶(HCM)对健康的中国绝经后妇女的体内维生素D状态和骨吸收标志物进行干预的影响。方法本试验对象为55岁以上,绝经至少5年的女性。共有124名女性进行了总体健康状况和骨密度检查筛选。63名女性被随机分为对照组和试验组,试验组在12w内每日饮用两次高钙/维生素D强化奶(含900 mg钙、96 mg镁、2.4 mg锌和6.4μg维生素D)。2组分别在试验开始、试验2 w、8 w和12 w时测量血矿物质、25(OH)维生素D3和Ⅰ型胶原C端肽(CTX)水平。结果对照组女性平均年龄为63±4.6岁,高钙强化奶(HCM)组女性平均年龄为62±3.8岁。所测得的每日钙摄入量的基线值为HCM组260~482 mg,对照组为252~692 mg。12 w后HCM组的平均身体质量指数(BMI)显著降低(P<0.05)。HCM组的血25(OH)维生素D3水平显著提高(33.13~39.49 nmol/L),而对照组则维持不变(29.27~28.21 nmol/L)。HCM组的血CTX水平在0 w和2 w之间下降了25%,并保持不变直至第12w。从第2w开始HCM组和对照组相比血CTX水平就出现了显著差异(P<0.001)。结论通过饮用含高钙和维生素D的强化奶(HCM),在2至4w内能显著提高中国绝经妇女体内维生素D水平,并减少骨吸收破坏。如果长期持续地饮用含高钙和维生素D的强化奶(HCM),能减少骨吸收和骨量丢失的风险,从而减少患骨质疏松和由此引起骨折的风险。 | Marlena C Kruger PengCheng Ha Joanne M Todd Barbara Kuhn-Sherlock Linda M Schollum Jiliang Ma George Qin Edith Lau | 2013 | 中国骨质疏松杂志2013，19，2： | 2 |
| 3 | Endoscopic High-Intensity Focused us: Technical Aspects and Studies in an in Vivo Porcine Model显示文摘 | Tong Li Tatiana Khokhlova Yak-Nam Wang Ezekiel Maloney Samantha D’Andrea Frank Starr Navid Farr Kyle Morrison George Keilman Joo Ha Hwang | 2014 | Gastrointestinal Endoscopy2014，，： | 1 |
| 4 | A survey of the management of spinal-induced hypotension for scheduled cesarean delivery显示文摘 | Allen TK Muir HA George RB | 2009 | Int J Obstet Anesth2009，18，4： | 1 |
| 5 | A survey of the man- agement of spinal-induced hypotension for scheduled cesare- an delivery 显示文摘 | Allen TK Muir HA George RB | 2009 | Int J Obstet Anesth2009，18，4： | 1 |
| 6 | A survery of the management of spinal-induced hypotension for scheduled cesarean delivery显示文摘 | Allen TK Muir HA George RB | 2009 | Int J Obstet Anesth2009，18，4： | 1 |
| 7 | Vagus nerve stimulation (VNS) for treatment -resistant depression: efficacy, side effects, and predictors of outcome显示文摘 | Sackeim HA Rush AJ George MS | 2001 | Neuropsychopharmacology2001，25，5： | 1 |
| 8 | Prevalence and Characteristics of Early Repolarization in the CASPER Registry显示文摘 | Nicolas Derval Christopher S. Simpson David H. Birnie Jeffrey S. Healey Vijay Chauhan Jean Champagne Martin Gardner Shubhayan Sanatani Raymond Yee Allan C. Skanes Lorne J. Gula Peter Leong-Sit Kamran Ahmad Michael H. Gollob Michel Ha?ssaguerre George J. K | 2011 | Journal of the American College of Cardiology2011，，7： | 1 |
| 9 | Purification of virus-like particles of recombinant human papillomavirus type 11 major capsid protein L1 from Saccharomyces cerevisiae显示文摘 | Cook JC Joyce JG George HA | | 0，，03： | 1 |
| 10 | Renal cortical ischemia in rabbits revealed by contrast-enhanced power Doppler sonography显示文摘 | George AT Carol EB Brent HA | 1998 | AJR1998，170，2： | 1 |
| 11 | Cytokine GM-CSF genetic adjuvant facilitates prophylactic DNA vaccine against pseudorabies virus through enhanced immune responses显示文摘 | Yoon HA Aleyas A George JA | 2006 | Microbiol Immunol2006，50，2： | 1 |
| 12 | 5-Lipoxygenase inhibitoryactivity of zileuton显示文摘 | George WC Patrick RY Daniel HA | 1991 | J Pharmacol Exp Ther1991，256，3： | 1 |
| 13 | Vagus nervestimulation(VNS)for treatment-resistant depres-sions:a multicenter study显示文摘 | Rush AJ George MS Sackeim HA | 2000 | Biol Psychiatry2000，47，： | 1 |
| 14 | Transcranial magnetic stimulation:applications in neuropsychiatry显示文摘 | George MS Lisanby SH Sackeim HA | 1999 | Arch Gen Psychi-atry1999，56，4： | 1 |
| 15 | Peaton virus: a new Simbu group arbovirus isolated from cattle and Culicoides brevitarsis in Australia显示文摘 | St George TD Standfast HA Cybinski DH | 1980 | Aust J Biol Sci1980，33，2： | 1 |
| 16 | Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFκB activation in vivo显示文摘 | Tuanzhu Ha Yuehua Li Xiang Gao Julie R. McMullen Tetsuo Shioi Seigo Izumo Jim L. Kelley Aiqiu Zhao Georges E. Haddad David L. Williams I. William Browder Race L. Kao Chuanfu Li | 2005 | Free Radical Biology and Medicine2005，，12： | 1 |
| 17 | Purification of virus-like particles of recombinant human papillomavirus type 11 major cap- sid protein L1 from Saccharomyces cerevisiae 显示文摘 | Cook JC Joyce JG George HA | 1999 | Protein Expr Purif1999，17，3： | 1 |
| 18 | Basilar and Middle Cerebral Artery Reserve A Comparative Study Using Transcranial Doppler and Breath-Holding Techniques显示文摘 | Kevin MB Robert HA Georg G | 2001 | Stroke2001，32，： | 1 |
| 19 | Transcranial magnetic stimulation:applications in neuropsychiatry显示文摘 | George MS Lisanby SH Sackeim HA | 1999 | Arch Gen Psychiatry1999，56，4： | 1 |
| 20 | A survey of the management of spinal-induced hypotension for scheduled cesarean delivery 显示文摘 | Allen TK Muir HA George RB | 2009 | Int J Obstet Anesth2009，18，4： | 1 |
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