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53篇 您的检索式：作者名="Georgia M"

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	题名	作者	年代	出处	被引量
1	Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders显示文摘Glutamate is the predominant excitatory neurotransmitter in the human brain and it has been shown that prolonged activation of the glutamatergic system leads to nerve damage and cell death. Following release from the pre-synaptic neuron and synaptic transmission, glutamate is either taken up into the presynaptic neuron or neighbouring glia by transmembrane glutamate transporters. Excitatory amino acid transporter(EAAT) 1 and EAAT2 are Na+-dependant glutamate transporters expressed predominantly in glia cells of the central nervous system. As the most abundant glutamate transporters, their primary role is to modulate levels of glutamatergic excitability and prevent spill over of glutamate beyond the synapse. This role is facilitated through the binding and transportation of glutamate into astrocytes and microglia. The function of EAAT1 and EAAT2 is heavily regulated at the levels of gene expression, post-transcriptional splicing, glycosylation states and cell-surface trafficking of the protein. Both glutamatergic dysfunction and glial dysfunction have been proposed to be involved in psychiatric disorder. This review will present an overview of the roles that EAAT1 and EAAT2 play in modulating glutamatergic activity in the human brain, and mount an argument that these two transporters could be involved in the aetiologies of schizophrenia and affective disorders as well as represent potential drug targets for novel therapies for those disorders.	Georgia M Parkin Madhara Udawela Andrew Gibbons Brian Dean	2018	World Journal of Psychiatry2018，8，2：	9
2	Self-organizing map for cluster analysis of a breast cancer database显示文摘	Mia K M Joseph Y L Georgia D T	2003	Artificial Intelligence in Medicine2003，27，：	1
3	Cooling for acute ischemic brain damage (cool aid):an open pilot study of induced hypothermia in acute ischemic stroke显示文摘	Krieger D W De Georgia M A Abou-Chebl A	2001	Stroke2001，32，：	1
4	Fever is associated with third ventricular shift after intracerebral hemorrhage: pathophysiologic implications 显示文摘	Deogaonkar A De Georgia M Bae C	2005	Neurol India2005，53，2：	1
5	Identification of Bartonella Species Directly in Clinical Specimens by PCR-Restriction Fragment Length Polymorphism Analysis of a 16S rRNA gene fragment显示文摘	Ghassan M Jane E Georgia Malcolm	1999	J Clin Microbiology1999，，37：	1
6	The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection显示文摘	Sheldon P Stone Ben S Cooper Chris C Kibbler Barry D Cookson Jenny A Roberts Graham F Medley Georgia Duckworth Rosalind Lai Shah Ebrahim Erwin M Brown Phil J Wiffen Peter G Davey	2007	The Lancet Infectious Diseases2007，，4：	1
7	Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis显示文摘	Stefan Leucht Andrea Cipriani Loukia Spineli Dimitris Mavridis Deniz ?rey Franziska Richter Myrto Samara Corrado Barbui Rolf R Engel John R Geddes Werner Kissling Marko Paul Stapf Bettina L?ssig Georgia Salanti John M Davis	2013	The Lancet2013，，：	1
8	Effect of sorbitol ad- dition on the physicochemical characteristics of starch - fatty acid systems 显示文摘	Georgia M Stylianos N R Sty\|ianos E	2010	Carbohydrate Polymers2010，79，：	1
9	Malignant' middle cerebral artery territory infarction:clinical course and prognostic signs显示文摘	Hacke W Schwab S Horn M Spranger M De Georgia M von Kummer R		0，，4：	1
10	The role of glutathione-S-transferase polymorphisms in ovarian cancer survival显示文摘	Christina M Nagle Georgia Chenevix-Trench Amanda B Spurdle	2007	European Journal of Cancer2007，43，2：	1
11	Kinetic modeling of coupled redox enzymatic systems for in situ regeneration of NADPH显示文摘	Fernanda M B Tania K F Georgia DC M	2002	J Mol Catal B :Enzymatic2002，1920，：	1
12	Development of a diet-lifestyle quality index for young children and its relation to obesity:The preschoolers diet-iifestyle index显示文摘	Yannis M Georgia K Evangelia G	2010	Public Health Nutrition2010，4，：	1
13	Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis显示文摘	Stefan Leucht Andrea Cipriani Loukia Spineli Dimitris Mavridis Deniz ?rey Franziska Richter Myrto Samara Corrado Barbui Rolf R Engel John R Geddes Werner Kissling Marko Paul Stapf Bettina L?ssig Georgia Salanti John M Davis	2013	The Lancet2013，，：	1
14	A Review of the factorial structure ofthe brief symptom inventory(BSI) : greek evidence显示文摘	AnthiL Georgia P Costantinos M	2008	International Journalof Testing2008，8，1：	1
15	Heterogeneous proliferative potential of occult metastatic cells in bone marrow of patients with solid epithelial tumors显示文摘	Oender S Christine M Georgia L	2002	Proc Natl Acad Sci USA2002，99，4：	1
16	p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors显示文摘	Georgia S Soliz R Li M	2006	Dev Biol2006，298，1：	1
17	On the recursive sequence xn+1 =a+xn/xn-1 显示文摘	Amleh A M Georgia D A Grove E A etal	1999	J Math Anal Appl1999，233，：	1
18	A meta-analysis of the association of N-Acetyltransferase 2 gene (NAT2) variants with breast cancer 显示文摘	Heather M Georgia W Robert CE	2007	American Journal of Epidemiology2007，166，：	1
19	Aberrant Neutrophil Functions in Stable Chronic Obstructive Pulm- onary Disease: the Neutrophil as an Immunotherapeutic Target 显示文摘	James A S Georgia M W Janet M L	2013	International Immunophamlacology2013，17，4：	1
20	Microbial diversity and dynamics during methane production from municipal solid waste 显示文摘	Christopher A B Georgia L Wolfee M	2013	Waste Management2013，，：	1

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