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| 1 | Budesonide induces complete remission in autoimmune hepatitis显示文摘瞄准:泼尼松和 azathioprine 为自体免疫的肝炎(AIH ) 代表标准疗法。然而,仅仅, 65% 病人进入完全的组织学的宽恕。最近, budesonide (芽) 被报导是一种有希望的选择。在这研究,我们在 AIH 估计了芽的功效和安全。方法:十八个病人(12 个女人, 6 个男人;吝啬的年龄 45.4+/-21 年) 与芽(Budenofalk ) 与 AIH 被对待在上面三次每日、跟随的 3 mg 为至少 24 wk.Seven,病人们也有主要胆汁性肝硬变(n=5 ) 或主要致硬化的胆管炎(n=2 ) 的特征。先进的肝纤维变性或肝硬化在 6 个病人是在场的。结果:十五(83%) 病人们有完全的临床、生物化学的宽恕。十个病人,与尖锐肝炎包括五,作为首要的治疗被给芽,哪个七进入宽恕。三个病人,二与肝肝硬化,没改善。有第二线的治疗的所有病人经历了长期的宽恕。组织学的宽恕也在三个病人被看见。临床上相关的导致芽的副作用与肝肝硬化(n=4 ) 仅仅在病人被记录。结论:芽在在我们有 AIH.Side 效果的病人的多数的宽恕正式就职是有效的,治疗失败主要与肝肝硬化在病人被观察。 | Antal Csepregi Christoph R(o|¨)cken Gerhard Treiber Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，9： | 14 |
| 2 | Acute exacerbation of autoimmune hepatitis induced by Twinrix显示文摘We report on a 26-year-old man who presented with severe jaundice and elevated serum liver enzyme activities after having received a dose of Twinrix(○R). In his past medical history, jaundice or abnormal liver function tests were never recorded. Following admission, an elevated immunoglobulin G level and antinuclear antibodies at a titer of 320 with a homogenous pattern were found. Histology of a liver biopsy showed marked bridging liver fibrosis and a chronic inflammation, compatible with autoimmune hepatitis. Treatment was started with budesonide and ursodeoxycholic acid,and led to complete normalization of the pathological liver function tests. We believe that Twinrix(○R) led to an acute exacerbation of an unrecognized autoimmune hepatitis in our patient. The pathogenesis remains to be clarified. It is tempting to speculate that inactivated hepatitis A virus and/or recombinant surface antigen of the hepatitis B virus -as seen in patients with chronic hepatitis C and unrecognized autoimmune hepatitis who were treated with interferon alpha-might have been responsible for disease exacerbation. | Antal Csepregi Gerhard Treiber Christoph R(o|¨)cken Peter Malfertheiner | 2005 | World Journal of Gastroenterology2005，11，26： | 2 |
| 3 | Technical aspects of biodiesel standards 显示文摘 | Gerhard K Robert O Dun | 1996 | Inform1996，7，8： | 1 |
| 4 | Technical aspects ofbiodiesel standards显示文摘 | Gerhard Knothe Dunn R O Bagby M O | 1996 | INFORM1996，7，8： | 1 |
| 5 | Knowledge management:Problems,promises,realities,and challenges显示文摘 | Gerhard F Jonathan O | 2001 | IEEE Intelligent Systems2001，16，1： | 1 |
| 6 | Dependence of oil stability index of fatty compounds on their structure and concentration and presence of metals显示文摘 | GERHARD KNOTHE ROBERT O DUNN | 2003 | J Am Oil Chem Soc2003，80，10： | 1 |
| 7 | Antibiotic-associated diar- rhea显示文摘 | SCHRODER O GERHARD R STEIN J | 2006 | Zeitschrift Gastroentero12006，44，2： | 1 |
| 8 | The LRU-K page replacement algorithm for database disk buffering显示文摘 | Elizabeth J. O’Neil Patrick E. O’Neil Gerhard Weikum | 1993 | ACM SIGMOD Record1993，，2： | 1 |
| 9 | Metal-poor Halo Stars as Tracers of ISM Mixing Processes During Halo Formation显示文摘 | ARGAST D SAMLAND M GERHARD O E | 2000 | A&A2000，356，： | 1 |
| 10 | Technical Aspects of Biodiesel Standards显示文摘 | GERHARD KNOTHE DDUNN R O BAGBY M O | 1996 | Inform1996，7，8： | 1 |
| 11 | Antibiotic associated diarrhea 显示文摘 | Schrder O Gerhard R Stein J | 2006 | Z Gastroenterol2006，44，2： | 1 |
| 12 | Antibiotic-associated diarrhea 显示文摘 | SCHRODER O GERHARD R STEIN J | 2006 | Z Gastroenterol2006，44，2： | 1 |
| 13 | Loss of heterozygosity at 11q23.3 in vasculoinvasive and metastatic squamous cell carcinoma of the cervix显示文摘 | O'Sullivan MJ Rader JS Gerhard DS | | 0，，： | 1 |
| 14 | Topoisomerase II-alfa gene as a predictive marker of response to anthracyclines in breast cancer显示文摘 | Almeida D Gerhard R Leito D | 2014 | Pathol Res Pract2014，14，14： | 1 |
| 15 | Knowledge management: Problems,promises, realities, and challenges 显示文摘 | Gerhard F Jonathan O | 2001 | IEEE Intelligent Systems2001，16，1： | 1 |
| 16 | Dependence of oil stability indexof fatty compounds on their structure and concentration and presence of metals显示文摘 | KNOTHE GERHARD DUNN ROBERT O | 2003 | Journal of the american oil chemists''-society2003，80，10： | 1 |
| 17 | Technical Aspects of Biodiesel Standards显示文摘 | GERHARD KNOTHE DDUNN R O BAGBY M O | 1996 | Inform1996，7，8： | 1 |
| 18 | Wearable EOG goggles:seamless sensing and context-awareness in everyday environments显示文摘 | Andreas Bulling Daniel Roggen Gerhard Tr(o)ster | 2009 | Journal of Ambient Intelligence and Smart Environments2009，1，2： | 1 |
| 19 | On Common Law Mens Rea 显示文摘 | Gerhard O W Mueller | 1957 | Minnesota Law Review1957，，42： | 1 |
| 20 | Antibiotic-associated diarrhea显示文摘 | Schroder O Gerhard R Stein J | 2006 | Gastroenterol2006，44，2： | 1 |
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