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| 1 | 中国谷物醋的感官风味特征分析显示文摘为了分析中国谷物醋(Chinese cereal vinegars,CCV)的感官风味特征,收集了中国四大传统名醋产区山西、四川、福建和江苏的8个品牌,3种不同陈酿程度的食醋产品共24个,对它们的感官风味进行了分析和比较。结果表明,仅巧克力味、烘焙味、肉汤味等少数几种风味是这些CCV产品共有的,而其他一些风味,如胶水味、水果味和甘草味,为某些CCV产品所特有。研究还发现,陈酿对提升CCV的烘焙味和巧克力味起到了非常关键的作用,而原材料在某些产品风味,如甘草味的形成中可能起到了重要作用。 | GIUDICI Paolo 陈福生 杨浩然 盛峰 LEMMETTI Federico BONCIANI Tommaso MARASTONI Emanuele CORRADINI Giuseppe | 2017 | 中国酿造2017，36，9： | 11 |
| 2 | Biliary tree gastrinomas in multiple endocrine neoplasia type 1 syndrome显示文摘AIM:To describe our patients affected with ectopic biliary tree gastrinoma and review the literature on this topic.METHODS:Between January 1992 and June 2012,28 patients affected by duodenopancreatic endocrine tumors in multiple endocrine neoplasia type 1(MEN1)syndrome underwent surgery at our institution.This retrospective review article analyzes our experience regarding seventeen of these patients subjected to duodenopancreatic surgery for Zollinger-Ellison syndrome(ZES).Surgical treatment consisted of duodenopancreatectomy(DP)or total pancreatectomy(TP).Regional lymphadenectomy was always performed.Any hepatic tumoral lesions found were removed during surgery.In MEN1 patients,removal of duodenal lesions can sometimes lead to persistence or recurrence of hypergastrinemia.One possible explanation for this unfavorable outcome could be unrecognized ectopic localization of gastrin-secreting tumors.This study described three cases among the seventeen patients who were found to have an ectopic gastrinoma located in the biliary tree.RESULTS:Seventeen MEN1 patients affected with ZES were analyzed.The mean age was 40 years.Fifteen patients underwent DP and two TP.On histopathological examination,duodeno pancreatic endocrine tumors were found in all 17 patients.Eighty-one gastrinomas were detected in the first three portions of the duodenum.Only one gastrinoma was found in the pancreas.The mean number of gastrinomas per patient was 5(range 1-16).Malignancy was established in 12 patients(70.5%)after lymph node,liver and omental metastases were found.Three patients exhibited biliary tree gastrinomas as well as duodenal gastrinoma(s).In two cases,the ectopic gastrinoma was removed at the same time as pancreatic surgery,while in the third case,the biliary tree gastrinoma was resected one year after DP because of recurrence of ZES.CONCLUSION:These findings suggest the importance of checking for the presence of ectopic gastrinomas in the biliary tree in MEN1 patients undergoing ZES surgery. | Francesco Tonelli Francesco Giudici Gabriella Nesi Giacomo Batignani Maria Luisa Brandi | 2013 | World Journal of Gastroenterology2013，19，45： | 3 |
| 3 | Immunomodulation by probiotics and prebiotics in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is the most prevalent primary malignancy in patients suffering from chronic liver diseases and cirrhosis.Recent attention has been paid to the involvement of the gut-liver axis(GLA)in HCC pathogenesis.This axis results from a bidirectional,anatomical and functional relationship between the gastrointestinal system and the liver.Moreover,the complex network of interactions between the intestinal microbiome and the liver plays a crucial role in modulation of the HCC-tumor microenvironment,contributing to the pathogenesis of HCC by exposing the liver to pathogen-associated molecular patterns,such as bacterial lipopolysaccharides,DNA,peptidoglycans and flagellin.Indeed,the alteration of gut microflora may disturb the intestinal barrier,bringing several toll-like receptor ligands to the liver thus activating the inflammatory response.This review explores the new therapeutic opportunities that may arise from novel insights into the mechanisms by which microbiota immunomodulation,represented by probiotics,and prebiotics,affects HCC through the GLA. | Edda Russo Camila Fiorindi Francesco Giudici Amedeo Amedei | 2022 | World Journal of Hepatology2022，14，2： | 2 |
| 4 | Is lymphatic status related to regression of inflammation in Crohn's disease?显示文摘AIM:To investigate the status of the lymphatic vessels in the small bowel affected by Crohn's disease(CD) at the moment of surgery.METHODS:During the period January 2011-June 2011,25 consecutive patients affected by CD were operated on in our Institution.During surgery,Patent Blue Ⅴ was injected subserosally and the way it spread along the subserosa of the intestinal wall,through the mesenterial layers towards the main lymphatic collectors and eventually to the lymph nodes was observed and recorded.Since some patients had been undergone strictureplasty at previous surgery,we also examined the status of intestinal lymph vessels after previous strictureplasties.The same procedure was performed in a control group of 5 patients affected by colorectal cancer.Length of lesions,caliber,maximal thickness of the diseased intestinal wall,thickness of the wall at injection site and thickness of the mesentery were evaluated at surgery.RESULTS:We observed three features after the injection of Patent Blue Ⅴ in the intestinal loops:(1) Macroscopically healthy terminal ileum of patients with CD or colon cancer showed thin lymphatic vessels linearly directed toward the mesentery;(2) In mild lesions in which the intestinal wall did not reach 8 mm of thickness,we observed short,wide and tortuous lymphatic vessels directed longitudinally along the intestinal axis toward disease-free areas and then transversally toward the mesentery;and(3) Injection in the severely affected lesions,that had a thickness of the intestinal wall over 10 mm,did not show any feature of lymphatic vessels at least on the subserosal surface.There was a correlation between the thickness of the parietal wall and the severity of the lymphatic alterations.Normal lymphatic vessels were observed at previous strictureplasties in the presence of complete regression of the inflammation.CONCLUSION:Injection of Patent Blue Ⅴ in the intestinal wall could help distinguish healthy tracts of the small bowel from those macroscopically borderline. | Francesco Tonelli Francesco Giudici Gadiel Liscia | 2012 | World Journal of Gastrointestinal Surgery2012，4，10： | 2 |
| 5 | Antithrombin III (ATILL) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study显示文摘 | F. Baudo T. M. Caimi F. deCataldo A. Ravizza S. Arlati G. Casella D. Carugo G. Palareti C. Legnani L. Ridolfi R. Rossi A. D’Angelo L. Crippa D. Giudici G. Gallioli A. Wolfler G. Calori | 1998 | Intensive Care Medicine1998，，4： | 2 |
| 6 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 7 | Long-term resuits of the direel repair of spondylolisthesis显示文摘 | GIUDICI F MINOIA L ARCHETTI M | 2011 | Eur Spine J2011，20，1： | 1 |
| 8 | Prevention of chronic fibrillation by pacing in the region of bachmann's bundle:Results of a multicenter randomized trial显示文摘 | Bailin SJ Adler S Giudici M | 2001 | J Cardivasc Electrophys2001，12，8： | 1 |
| 9 | The Ablate and Pace Trial: A Prospective Study of Catheter Ablation of the AV Conduction System and Permanent Pacemaker Implantation for Treatment of Atrial Fibrillation显示文摘 | G. Neal Kay Kenneth A. Ellenbogen Michael Giudici Margaret M. Redfield Louise S. Jenkins Marcus Mianulli Bruce Wilkoff | 1998 | Journal of Interventional Cardiac Electrophysiology1998，，2： | 1 |
| 10 | Molecular stability of chemically modified collagen triple helices显示文摘 | Giudici G Viola M | 2003 | Federation of Eu ropean Biochemical Societies2003，547，3： | 1 |
| 11 | A proposal to improve the supply of orphan drugs显示文摘 | Minghetti P Giudici E Montanari L | 2000 | Pharmacol Res2000，42，1： | 1 |
| 12 | The Provision of Finance to Innovation :A Survey Conducted among Italian Technology - based Small Firms显示文摘 | GIUDICI G PALEARI S | 2000 | Small Business Economics2000，14，： | 1 |
| 13 | Long-term results of the direct repair of spondylolisthesis显示文摘 | Giudici F Minoia L Archetti M | 2011 | Eur Spine J2011，20，11： | 1 |
| 14 | Comparison of the haemodynamic effects of right ventricular outflow2tract pacingwith right ventricular apex pacing 显示文摘 | Cock CC Giudici MC Twisk JW | 2003 | Europace2003，5，3： | 1 |
| 15 | Comparison of right ventricular out fl ow tract and apical lead permanent pacing on cardiac output显示文摘 | Giudici MC Thornbug GA Buck DL | 1997 | Am J Cardiol1997，79，2： | 1 |
| 16 | The cytotoxic properties of a plant lipid transfer protein involve membrane permeabilization of target cells显示文摘 | REGENTE M C GIUDICI A M VILLALAIN J CANAL L | 2005 | Lett in Appl Mierobiol2005，40，： | 1 |
| 17 | Long-term results of pediculo-body fixation and posterolateral fusion for lumbar spondylolisthesis显示文摘 | Zagra A Giudici F Minoia L | 2009 | Eur Spine J2009，18，1： | 1 |
| 18 | Oral administration of an antiprogesterone (Mifepristone, RU486) for preparing the cervix uteri for pregnancy interruption during the first trimester显示文摘 | De Grandi P Giudici G | 1989 | J Gynecol Obstet Biol Reprod (Paris)1989，18，6： | 1 |
| 19 | Comparison of the haemo- dynamic effects of right ventricular outflow-tract pacing with right ventricular apex pacing:a quantitative review显示文摘 | De Cock CC Giudici MC Twisk JW | 2003 | Europace2003，5，3： | 1 |
| 20 | Comparison of right ventricular outflow tract and apical lead perma- nent pacing on cardiac output显示文摘 | Giudici MC Thornberg GA Buck DL | 1997 | Am J Cardiol1997，79，2： | 1 |
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