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| 1 | Gastroesophageal reflux and congenital gastrointestinal malformations显示文摘Although the outcome of newborns with surgical congenital diseases(e.g.,diaphragmatic hernia;esophageal atresia;omphalocele;gastroschisis) has improved rapidly with recent advances in perinatal intensive care and surgery,infant survivors often require intensive treatment after birth,have prolonged hospitalizations,and,after discharge,may have longterm sequelae including gastro-intestinal comorbidities,above all,gastroesophageal reflux(GER).This condition involves the involuntary retrograde passage of gastric contents into the esophagus,with or without regurgitation or vomiting.It is a well-recognized condition,typical of infants,with an incidence of 85%,which usually resolves after physiological maturation of the lower esophageal sphincter and lengthening of the intra-abdominal esophagus,in the first few months after birth.Although the exact cause of abnormal esophageal function in congenital defects is not clearly understood,it has been hypothesized that common(increased intra-abdominal pressure after closure of the abdominal defect) and/or specific(e.g.,motility disturbance of the upper gastrointestinal tract,damage of esophageal peristaltic pump) pathological mechanisms may play a role in the etiology of GER in patients with birth defects.Improvement of knowledge could positively impact the long-term prognosis of patients with surgical congenital diseases.The present manuscript provides a literature review focused on pathological and clinical characteristics of GER in patients who have undergone surgical treatment for congenital abdominal malformations. | Lucia Marseglia Sara Manti Gabriella D'Angelo Eloisa Gitto Carmelo Salpietro Antonio Centorrino Gianfranco Scalfari Giuseppe Santoro Pietro Impellizzeri Carmelo Romeo | 2015 | World Journal of Gastroenterology2015，21，28： | 3 |
| 2 | Balanced propofol sedation administered by nonanesthesiologists:The first Italian experience显示文摘AIM:To assess the efficacy and safety of a balanced approach using midazolam in combination with propofol,administered by nonanesthesiologists,in a large series of diagnostic colonoscopies.METHODS:Consecutive patients undergoing diagnostic colonoscopy were sedated with a single dose of midazolam(0.05 mg/kg)and lowdose propofol(starter bolus of 0.5 mg/kg and repeated boluses of 10 to 20 mg).Induction time and deepest level of sedation,adverse and serious adverse events,as well as recovery times,were prospectively assessed.Cecal intubation and adenoma detection rates were also collected.RESULTS:Overall,1593 eligible patients were included.The median dose of propofol administered was 70 mg(range:40120 mg),and the median dose of midazolam was 2.3 mg(range:24 mg).Median induction time of sedation was 3 min(range:14 min),and median recovery time was 23 min(range:1040 min).A moderate level of sedation was achieved in 1561(98%) patients,whilst a deep sedation occurred in 32(2%) cases.Transient oxygen desaturation requiring further oxygen supplementation occurred in 8(0.46%;95% CI:0.2%0.8%)patients.No serious adverse event was observed.Cecal intubation and adenoma detection rates were 93.5%and 23.4%(27.8%for male and 18.5%for female,subjects),respectively.CONCLUSION:A balanced sedation protocol provided a minimalization of the dose of propofol needed to target a moderate sedation for colonoscopy,resulting in a high safety profile for nonanesthesiologist propofol sedation. | Alessandro Repici Nico Pagano Cesare Hassan Alessandra Carlino Giacomo Rando Giuseppe Strangio Fabio Romeo Angelo Zullo Elisa Ferrara Eva Vitetta Daniel de Paula Pessoa Ferreira Silvio Danese Massimo Arosio Alberto Malesci | 2011 | World Journal of Gastroenterology2011，17，33： | 2 |
| 3 | Quality of bowel preparation in patients with inflammatory bowel disease undergoing colonoscopy:What factors to consider?显示文摘An adequate bowel preparation in patients with inflammatory bowel disease(IBD)is a prerequisite for successful colonoscopy for screening,diagnosis,and surveillance.Several bowel preparation formulations are available,both high-and low-volume based on polyethylene glycol.Generally,low-volume formulations are also based on several compounds such as magnesium citrate preparations with sodium picosulphate,oral sulphate solution,and oral sodium phosphatebased solutions.Targeted studies on the quality of bowel preparation prior to colonoscopy in the IBD population are still required,with current evidence from existing studies being inconclusive.New frontiers are also moving towards the use of alternatives to anterograde ones,using preparations based on retrograde colonic lavage. | Antonietta Gerarda Gravina Raffaele Pellegrino Mario Romeo Giovanna Palladino Marina Cipullo Giorgia Iadanza Simone Olivieri Giuseppe Zagaria Nicola De Gennaro Antonio Santonastaso Marco Romano Alessandro Federico | 2023 | World Journal of Gastrointestinal Endoscopy2023，15，3： | 2 |
| 4 | Aortic and left ventricular remodeling in patients with bicuspid aortic valve without significant valvular dysfunction: A prospective study显示文摘 | Giuseppe Santarpia Giancarlo Scognamiglio Giovanni Di Salvo Michele D’Alto Berardo Sarubbi Emanuele Romeo Ciro Indolfi Maurizio Cotrufo Raffaele Calabrò | 2011 | International Journal of Cardiology2011，，3： | 1 |
| 5 | Potential pitfalls of 18F-FDG PET in a large series of patients treated for malignant lymphoma: prevalence and scan interpretation显示文摘 | Paolo Castellucci Cristina Nanni Mohsen Farsad Lapo Alinari PierLuigi Zinzani Vittorio Stefoni Giuseppe Battista Daria Valentini Cinzia Pettinato Mario Marengo Stefano Boschi Romeo Canini Michele Baccarani Nino Monetti Roberto Franchi Lucia Rampin Stefano | 2005 | Nuclear Medicine Communications2005，，8： | 1 |
| 6 | 18F-FDG PET in malignant lymphoma: significance of positive findings显示文摘 | Paolo Castellucci PierLuigi Zinzani Michael Pourdehnad Lapo Alinari Cristina Nanni Mohsen Farsad Giuseppe Battista Monica Tani Vittorio Stefoni Romeo Canini Nino Monetti Domenico Rubello Abass Alavi Roberto Franchi Stefano Fanti | 2005 | European Journal of Nuclear Medicine and Molecular Imaging2005，，7： | 1 |
| 7 | Alexithymia, Negative Emotions, and Sexual Behavior in Heterosexual University Students from Italy显示文摘 | Giuseppe Scimeca Antonio Bruno Gianluca Pandolfo Umberto Micò Vincenzo M. Romeo Elisabetta Abenavoli Adriano Schimmenti Rocco Zoccali Maria R. A. Muscatello | 2012 | Archives of Sexual Behavior2012，，1： | 1 |
| 8 | Role of genomics in cardiovascular medicine显示文摘As all branches of science grow and new experimental techniques become readily accessible,our knowledge of medicine is likely to increase exponentially in the coming years.Recently developed technologies have revolutionized our analytical capacities,leading to vast knowledge of many genes or genomic regions involved in the pathogenesis of congenital heart diseases,which are often associated with other genetic syndromes,coronary artery disease and non-ischemic cardiomyopathies and channelopathies.The knowledge-base of the genesis of cardiovascular diseases is likely going to be further revolutionized in this new era of genomic medicine.Here,we review the advances that have been made over the last several years in this field and discuss different genetic mechanisms that have been shown to underlie a variety of cardiovascular diseases. | Giuseppe Novelli Irene M Predazzi Ruggiero Mango Francesco Romeo Jawahar L Mehta | 2010 | World Journal of Cardiology2010，2，12： | 1 |
| 9 | Arrhythmias and Hemodialysis: Role of Potassium and New Diagnostic Tools显示文摘 | Michele Buemi Giuseppe Coppolino Davide Bolignano Alessio Sturiale Susanna Campo Antoine Buemi Eleonora Crascì Adolfo Romeo | 2009 | Renal Failure2009，，1： | 1 |
| 10 | Inflammatory bowel diseases patients suffer from significant low levels and barriers to physical activity:The“BE-FIT-IBD”study显示文摘BACKGROUND The place regular physical activity(PA)should occupy in managing patients with inflammatory bowel diseases(IBD)is unclear.AIM To assess PA levels and barriers in a southern Italian IBD population.METHODS IBD patients with non-severe disease activity[assessed with partial Mayo score for ulcerative colitis(UC)and Harvey-Bradshaw index for Crohn’s disease]were approached to receive an anonymous online questionnaire to assess PA levels using the International Physical Activity Questionnaire(IPAQ)and to assess disease activity as patient-reported outcomes 2(PRO-2)and finally to assess habits,beliefs and barriers in conducting regular PA.Clinical,anthropometric and demographic data of patients were also collected.PA was expressed as continuous units of resting metabolic rate(Met)in min/wk.Three PA groups were identified:Inactive(<700 Met min/wk),sufficiently active(700-2500 Met min/wk)and health enhancing PA(HEPA)(i.e.,HEPA active,>2500 Met min/wk)patients.RESULTS Included patients(219)showed overall PA levels of 834.5 Met min/wk,with a large proportion(94,42.9%)classified as inactive while only a minority(9,4.1%)as health-enhancing PA.Patients without dyslipidaemia(P<0.0001)or on biologics therapy(P=0.022)showed better IPAQ scores in moderate activities.UC PRO-2 correlated negatively with IPAQ intense activities scores(τ=-0.156,P=0.038).PRO-2 did not show notable sensitivity/specificity in predicting IPAQ inactivity(AUC<0.6).IBD activity did not differ between active and inactive patients(P>0.05).Active patients expressed the need to discuss PA with their gastroenterologist.Some barriers(e.g.,diagnosis of IBD and fear of flare-ups after PA)are significantly more reported by inactive patients.CONCLUSION A significant rate of physical inactivity was recorded in this setting.IPAQ showed good feasibility.PA should be an element of discussion in IBD visits assessed quickly with non-invasive questionnaires. | Antonietta Gerarda Gravina Raffaele Pellegrino Tommaso Durante Giovanna Palladino Rossella D’Onofrio Simone Mammone Giusi Arboretto Salvatore Auletta Giuseppe Imperio Andrea Ventura Mario Romeo Alessandro Federico | 2023 | World Journal of Gastroenterology2023，29，41： | 1 |
| 11 | Glenoid and humeral head bone loss in traumatic anterior glenohumeral instability: a systematic review显示文摘 | Umile Giuseppe Longo Mattia Loppini Giacomo Rizzello Giovanni Romeo Polydoor Emile Huijsmans Vincenzo Denaro | 2014 | Knee Surgery Sports Traumatology Arthroscopy2014，，2： | 1 |
| 12 | Endoscopic submucosal dissection in patients with early esophageal squamous cell carcinoma: results from a prospective Western series显示文摘 | Alessandro Repici Cesare Hassan Alessandra Carlino Nico Pagano Angelo Zullo Giacomo Rando Giuseppe Strangio Fabio Romeo Rinaldo Nicita Riccardo Rosati Alberto Malesci | 2010 | Gastrointestinal Endoscopy2010，，： | 1 |
| 13 | Telemedicine in inflammatory bowel diseases:A new brick in the medicine of the future?显示文摘Inflammatory bowel disease(IBD)is a chronic digestive disease that requires continuous monitoring by healthcare professionals to determine the appropriate therapy and monitor short-term and long-term complications.The progressive development of information technology has enabled healthcare personnel to deliver care services to patients remotely.Therefore,various applications of telemedicine in IBD management have evolved,including telemonitoring,teleconsulting,teleducation,telenursing,telenutrition,and telepathology.While evidence has been provided for some telemedicine applications,targeted studies are still required.This review summarises the major studies that have evaluated telemedicine and its application in the management of IBD. | Antonietta Gerarda Gravina Raffaele Pellegrino Tommaso Durante Giovanna Palladino Rossella D'Onofrio Simone Mammone Giusi Arboretto Salvatore Auletta Giuseppe Imperio Andrea Ventura Mario Romeo Alessandro Federico | 2023 | World Journal of Methodology2023，13，4： | 0 |
| 14 | Short-term changes in soil properties after prescribed fire and mulching with fern in Mediterranean forests显示文摘Prescribed fire,although having low intensity and being able to reduce the risk of wildfire may modify soil properties in the short term,with possible increases in runoffand erosion risk.Soil mulching with vegetation residues is one of the most common post-fire management strategies.Residues of fern,which is abundant on the Mediterranean forest floor,may be used to replace straw for mulching fireaffected areas.However,the effects of prescribed fires are not completely understood,and there is no data regarding the use of fern to protect soil after fire in the literature.To fill this gap,selected soil chemical parameters were analyzed,on a comparative basis,in three Mediterranean forests(pine,oak and chestnut)in Calabria(Southern Italy).These parameters were measured immediately and one year after fire in unburned,burned and not treated,and burned and mulched soils.Changes in soil chemical properties among the different treatments were significant,and the effects of the prescribed fire and mulching were dependent on the time elapsed from their application and forest species.In general,mulching was not effective in limiting the changes in the monitored soil properties compared to the pre-fire values.Each forest species showed different temporal trends in changes of soil properties. | Bruno Gianmarco Carra Giuseppe Bombino Manuel Esteban Lucas-Borja Adele Muscolo Federico Romeo Demetrio Antonio Zema | 2022 | Journal of Forestry Research2022，33，4： | 0 |
| 15 | Classifying Cardiac Anomalies in Right and Left Isomerism:Concordant and Discordant Patterns显示文摘Aims:Evidence is emerging that,in the setting of isomerism,the atrial and bronchial arrangement are not always concordant,nor are these patterns always harmonious with the arrangement of the abdominal organs.We aimed to evaluate the concordance between these features in a cohort of patients with cardiac malformations in the setting of known isomerism,seeking to determine whether it was feasible to assess complexity on this basis,in this regard taking note of the potential value of bronchial as opposed to appendage morphology.Methods and Results:We studied 78 patients known to have isomerism of the bronchuses,43 with right and 35 with left isomerism.Appendage anatomy could be determined in 49 cases(63%),all but one of these being concordant with bronchial anatomy.When assessing abdominal features,in only 59 cases(76%)was splenic morphology in keeping with the thoracic findings.As expected,right isomerism was associated with greater complexity of cardiac malformations,with an odds ratio of 6.53,with confidence intervals from 2.2–19.3(p<0.001).The odds were slightly decreased with thoraco-abdominal disharmony,when lesions shown to carry higher risk were then found in the setting of left isomerism.Conclusion:Harmony is excellent between bronchial and appendage isomerism,but less so with the arrangement of the abdominal organs.Right isomerism in our cohort,was indicative of a sixfold increase in intracardiac complexity.When discordance was found between the systems,however,the cardiac anomalies were less typical of the anticipated findings for right vs.left isomerism of the appendages. | Lilia Oreto Giuseppe Mandraffino Paolo Ciliberti Teresa P.Santangelo Placido Romeo Antonio Celona Placido Gitto Lorenzo Galletti Fiore S.Iorio Alfredo Di Pino Aurelio Secinaro Paolo Guccione Robert H.Anderson Salvatore Agati | 2023 | Congenital Heart Disease2023，18，1： | 0 |
| 16 | Environmental factors determining growth of salamander larvae: A field study显示文摘 | Laura LIMONGI Gentile Francesco FICETOLA Giuseppe ROMEO Raoul MANENTI | 2015 | Current Zoology2015，61，3： | 0 |
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