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| 1 | Predicting Protein Subcellular Localization: Past, Present, and Future显示文摘Functional characterization of every single protein is a major challenge of the postgenomic era. The large-scale analysis of a cell's proteins, proteomics, seeks to provide these proteins with reliable annotations regarding their interaction partners and functions in the cellular machinery. An important step on this way is to determine the subcellular localization of each protein. Eukaryotic cells are divided into subcellular compartments, or organelles. Transport across the membrane into the organelles is a highly regulated and complex cellular process. Predicting the subcellular localization by computational means has been an area of vivid activity during recent years. The publicly available prediction methods differ mainly in four aspects: the underlying biological motivation, the computational method used, localization coverage, and reliability, which are of importance to the user.This review provides a short description of the main events in the protein sorting process and an overview of the most commonly used methods in this field. | Pierre Dnnes Annette Hglund | 2004 | Genomics, Proteomics & Bioinformatics2004，2，4： | 4 |
| 2 | Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer显示文摘 | Glunde K Artemov D Penet M F | 2010 | Chem Rev2010，110，5： | 1 |
| 3 | Approx?imate geodesic distances reveal biologically relevant structures in microarray data显示文摘 | NILSSONJ FIORETOS T W GLUND M | 2004 | Bioinforrnarics2004，，6： | 1 |
| 4 | DICTRA, a tool for simulation of diffusional transformations in alloys显示文摘 | Annika Borgenstam Lars H?glund John ?gren Anders Engstr?m | 2000 | Journal of Phase Equilibria2000，，3： | 1 |
| 5 | Choline metabolism in malignant transformation显示文摘 | Glunde K Bhujwalla ZM Ronen SM | 2011 | Nat Rev Cancer2011，11，12： | 1 |
| 6 | A randomised study in healthy volunteers to investigate the safety, tolerability and pharmacokinetics of idarucizumab, a specific antidote to dabigatran 显示文摘 | Glund S Moschetti V Norris S | 2015 | Thromb Haemost2015，113，5： | 1 |
| 7 | Clinical pharmacology of thalidomide显示文摘 | ERIKSSON T BJRKMAN S HGLUND P | | 0，，： | 1 |
| 8 | Dynamic coupling of computational fluid dynamics and thermodynamics software: applied on a top blown converter显示文摘 | Mikael ERSSON Lars H?GLUND Anders TILLIANDER | 2008 | ISIJ International2008，48，2： | 1 |
| 9 | Idarucizumab, a specific antidote for dabigatran: immediate, complete and sustained reversal of dabigatran induced anticoagulati6n in elderly and renally impaired subjects 显示文摘 | Glund S Stangier J Schmohl M | 2014 | Blood2014，124，： | 1 |
| 10 | Current perspectives of natural killer cell education by MHC class Ⅰ molecules显示文摘 | H(o)glund P Brodin P | 2010 | Nature Reviews Immunology2010，10，10： | 1 |
| 11 | Single nucleotide polymorphisms in the XPG gene:determination of role in DNA repair and breast cancer risk显示文摘 | Kumar R H(o)glund L Zhao C | | 0，，05： | 1 |
| 12 | Magnetic resonance spec- troscopy in metabolic and molecular imaging and diagnosis of canc- er显示文摘 | Glunde K Artemov D Penet MF | 2010 | Chem Rev2010，110，5： | 1 |
| 13 | Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry显示文摘 | Martin H?glund Fredrik Sandin Karin Hellstr?m Mats Bj?reman Magnus Bj?rkholm Mats Brune Arta Dreimane Marja Ekblom S?ren Lehmann Per Ljungman Claes Malm Berit Markev?rn Kristina Myhr-Eriksson Lotta Ohm Ulla Olsson-Str?mberg Anders Sj?lander Hans Wadenvik | 2013 | Blood2013，，： | 1 |
| 14 | Molecular causes of the aberrant choline phospholipid metabolism in breast cancer显示文摘 | Glunde K Jie C Bhujwalla ZM | 2004 | Cancer Res2004，64，： | 1 |
| 15 | Molecular Causes of the aberrant choline phospholipids metabolism in breast cancer显示文摘 | Glunde K J C Bhujwalla ZM | 2004 | Cancer Res2004，64，12： | 1 |
| 16 | AMPK-medi- ated AS160 phosphorylation in skeletal muscle is depen- dent on AMPK catalytic and regulatory subunits 显示文摘 | Treebak JT Glund S Deshmukh A | 2006 | Diabetes2006，55，7： | 1 |
| 17 | Molecular causes of the aberrantcholine phospholipid metabolism in breast cancer显示文摘 | Glunde K Jie C Bhujwalla ZM | 2004 | CancerRes2004，64，12： | 1 |
| 18 | RNA interference-mediated choline kinase suppression in breast cancer cells induces differentiation and reduces proliferation显示文摘 | Glunde K Raman V Mori N | 2005 | Cancer Res2005，65，11： | 1 |
| 19 | 5'-AMP-activated protein kinase regulates skeletal muscle glycogen content and ergogenics显示文摘 | BRIAN R BARNES STEPHAN GLUND YUN CHAU LONG | 2005 | Faseb J2005，，19： | 1 |
| 20 | Further mutations in Brain 4(POU3F4) clarify the phenotype in the X linked deafness,DFN3显示文摘 | Bitner-Glindzicz M Turnpenny ILl{ glund P ct al | 1995 | ttuman molecular genetics1995，4，8： | 1 |
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