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| 1 | Prospective evaluation of a pharmacogenetics-guided warfarin loading and maintenance dose regimen for initiation of therapy显示文摘 | GONG IY TIRONA RG SCHWARZ UI | 2011 | Blood2011，118，11： | 1 |
| 2 | Medial sural artery perforator flap for repair of the hand显示文摘 | Xie RG Gu JH Gong YP | 2007 | J Hand Surg Eur Vol2007，32，5： | 1 |
| 3 | Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence显示文摘 | Bedolla RG Gong J Prihoda TJ | 2012 | PLo S One2012，7，9： | 1 |
| 4 | Medial sural artery perforator flap for repair of the hand显示文摘 | Xie RG Gu JH Gong YP | 2007 | J Hand Surg Eur Vol2007，32，5： | 1 |
| 5 | Genotoxicity of 2,4- and 2,6-dinitrotoluene as measured by the Tradescantia micronucleus (Trad-MCN) bioassay显示文摘 | Gong P Kuperman RG Sunahara Gl | 2003 | Mutation Research-genetic Toxicology and Environmental Mutagenesis2003，538，12： | 1 |
| 6 | The expression profile of mi-croRNAs in a model of 7,12-dimethyl-benzanthrance-in-duced oral carcinogenesis in Syrian hamster显示文摘 | Yu T Wang XY Gong RG | 2009 | J Exp ClinCancer Res2009，28，： | 1 |
| 7 | Medial sural artery perforator flap for repair of the hand 显示文摘 | Xie RG Gu JH Gong YP Tang JB | 2007 | J Hand Surg2007，，： | 1 |
| 8 | The expression profile of mi-croRNAs in a model of 7,12 - dimethyl - benzanthrance - in-duced oral carcinogenesis in Syrian hamster 显示文摘 | Yu T Wang XY Gong RG | 2009 | J Exp ClinCancer Res2009，28，2： | 1 |
| 9 | Genotoxicity of 2,4- and 2,6-dinitrotoluene as measured by the Tradescantia micronucleus (Trad-MCN) bioassay显示文摘 | Gong P Kuperman RG Sunahara GI | 2003 | Mutation Research-genetic Toxicology and Environmental Mutagenesis2003，538，12： | 1 |
| 10 | The expression profile of microRNAs in a model of 7,12-dimethyl-benzanthrance-induced oral carcinogenesis in Syrian hamster显示文摘 | Yu T Wang XY Gong RG | 2009 | J Exp Clin Cancer Res2009，28，： | 1 |
| 11 | Prospective e- valuation of a pharmacogenetics-guided warfarin load- ing and maintenance dose regimen for initiation of therapy显示文摘 | Gong IY Tirona RG Schwarz UI | 2011 | Blood2011，118，11： | 1 |
| 12 | LDL receptor-related protein 5(LRP5)affects bone accrual and eye development显示文摘 | Gong Y Slee RB Fukai N Rawadi G Roman-Roman S Reginato AM Wang H Cundy T Glorieux FH Lev D Zacharin M Oexle K Marcelino J Suwairi W Heeger S Sabatakos G Apte S Adkins WN Allgrove J Arslan-Kirchner M Batch JA Beighton P Black GC Boles RG Boon LM Borrone C | | 0，，： | 1 |
| 13 | The expression profile of mi- croRNAs in a model of 7,12-dimethyl-benzanthrance-induced oral carcinogenesis in Syrian hamster显示文摘 | Yu T Wang XY Gong RG | 2009 | J Exp Clin Cancer Res2009，28，： | 1 |
| 14 | The expression profile of microRNAs in a model of 7,12-dimethyl-benzanthrance- induced oral carcinogenesis in Syrian hamster 显示文摘 | YU T WANG XY GONG RG | 2009 | J Exp Clin Cancer Res2009，28，1： | 1 |
| 15 | Development and testing ofthe Test of Functional Health Literacy in Dentistry(TOFHLiD)显示文摘 | GONG DA4 LEE JY ROZIER RG | 2007 | JPublic Health Dent2007，67，2： | 1 |
| 16 | Reflux of bile induces esophageal mucosal inflammation and apoptosis in rats 显示文摘 | Zhang R Gong J Shi RG | 2006 | Sichuan Da Xue Xue Ban Yi Xue Ban2006，37，5： | 1 |
| 17 | The expression profile of microRNAsin a model of 7, 12--dimethyl--benzan- thrance--induced oral carcinogenesis in Syrian hamster 显示文摘 | Yu T Wang XY Gong RG | 2009 | J Exp Clin Cancer Res2009，28，： | 1 |
| 18 | Development and testing of the test of functional health literacy in dentistry (TOFHLiD) 显示文摘 | Gong DA Lee JY Rozier RG | 2007 | J Pub Heal Dent2007，67，2： | 1 |
| 19 | Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence显示文摘 | Bedolla RG Gong J Prihoda TJ | 2012 | PLoS One2012，7，44： | 1 |
| 20 | Ca^(2+)-dependent successive phosphorylation of vacuolar transporter MTP8 by CBL2/3-CIPK3/9/26 and CPK5 is critical for manganese homeostasis in Arabidopsis显示文摘Manganese(Mn)is an essential micronutrient for all living organisms.However,excess Mn supply that can occur in acid or waterlogged soils has toxic effects on plant physiology and development.Although a variety of Mn transporter families have been characterized,we have only a rudimentary understanding of how these transporters are regulated to uphold and adjust Mn homeostasis in plants.Here,we demonstrate that two calcineurin-B-like proteins,CBL2/3,and their interacting kinases,CIPK3/9/26,are key regulators of plant Mn homeostasis.Arabidopsis mutants lacking CBL2 and 3 or their interacting protein kinases CIPK3/9/26 exhibit remarkably high Mn tolerance.Intriguingly,CIPK3/9/26 interact with and phosphorylate the tonoplast-localized Mn and iron(Fe)transporter MTP8 primarily at Ser35,which is conserved among MTP8 proteins from various species.Mn transport complementation assays in yeast combined with multiple physiological assays indicate that CBL-CIPK-mediated phosphorylation of MTP8 negatively regulates its transport activity from the cytoplasm to the vacuole.Moreover,we show that sequential phosphorylation of MTP8,initially at Ser31/32 by the calcium-dependent protein kinase CPK5 and subsequently at Ser35 by CIPK26,provides an activation/deactivation fine-tuning mechanism for differential regulation of Mn transport.Collectively,our findings define a two-tiered calcium-controlled mechanism for dynamic regulation of Mn homeostasis under conditions of fluctuating Mn supply. | Chuanfeng Ju Zhenqian Zhang Jinping Deng Cuicui Miao Zhangqing Wang Lukas Wallrad Laiba Javed Dali Fu Ting Zhang Jörg Kudla Zhizhong Gong Cun Wang | 2022 | Molecular Plant2022，15，3： | 0 |
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