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| 1 | Soy-based renoprotection显示文摘Chronic kidney disease(CKD) is a significant publich ealth problem as risk factors such as advanced age, obesity, hypertension and diabetes rise in the global po-pulation. Currently there are no effective pharmacologic treatments for this disease. The role of diet is important for slowing the progression of CKD and managing symptoms in later stages of renal insufficiency. While low protein diets are generally recommended, maintaining adequate levels of intake is critical for health. There is an increasing appreciation that the source of protein may also be important. Soybean protein has been the most extensively studied plant-based protein in subjects with kidney disease and has demonstrated renal protective properties in a number of clinical studies. Soy protein consumption has been shown to slow the decline in estimated glomerular filtration rate and significantly improve proteinuria in diabetic and non-diabetic patients with nephropathy. Soy's beneficial effects on renal function may also result from its impact on certain phy-siological risk factors for CKD such as dyslipidemia, hypertension and hyperglycemia. Soy intake is also associated with improvements in antioxidant status and systemic inflammation in early and late stage CKD pati-ents. Studies conducted in animal models have helped to identify the underlying molecular mechanisms that may play a role in the positive effects of soy protein on renal parameters in polycystic kidney disease, metabolically-induced kidney dysfunction and age-associated prog-ressive nephropathy. Despite the established relationship between soy and renoprotection, further studies are needed for a clear understanding of the role of the cellular and molecular target(s) of soy protein in main-taining renal function. | Nancy J Mc Graw Elaine S Krul Elizabeth Grunz-Borgmann Alan R Parrish | 2016 | World Journal of Nephrology2016，5，3： | 5 |
| 2 | Structural and bio mechanical responses of osseous healing: a novel murine nonun- ion model显示文摘 | Chaubey A Grawe B Meganck J A | 2013 | J Orthop Traumatol2013，14，4： | 1 |
| 3 | Genetics of crystallins:Cataract and beyond显示文摘 | Graw J | | 0，，02： | 1 |
| 4 | Induction of micronuclei in mouse and rat by glycidamide, genotoxic mctabolite of acrylamide显示文摘 | PAULSSON B KOTOVA N GRAWE J | 2003 | Mutat Res2003，535，1： | 1 |
| 5 | Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P显示文摘 | Graw J Klopp N Illig T | | 0，，08： | 1 |
| 6 | Genetics of crystallins:cataract and beyond显示文摘 | Graw J | | 0，，： | 1 |
| 7 | Characterization of a new dominant V124E mutation in the mouse a A-crystallin-encoding gene显示文摘 | Graw J Loster J Soewarto D | | 0，，12： | 1 |
| 8 | The muhiplicative model for cancer risk assessment:aplicability to acrylamide显示文摘 | Paulsson B Granath F Grawe J | | 0，，： | 1 |
| 9 | Mutation in intron 6 of the hamster Mitf gene leads to skipping of the subsequent exon and creates a novel animal model for the human Waardenburg syndrome type II显示文摘 | Graw J Pretsch W Loster J | 2003 | Ge- netics2003，164，3： | 1 |
| 10 | Induction of micronuclei in mouse and rat by ghucidamide, genotoxic metabolite of acrylamide 显示文摘 | Paulsson B Kotova N Grawe J | 2003 | Murat Res2003，535，1： | 1 |
| 11 | Cataract mutations as a tool for developmental genecticists 显示文摘 | Graw J | 1996 | Ophthalmic Res1996，281，： | 1 |
| 12 | Induction of icronuclPi in mouse and rat by glucidamide, genotoxic metabolite of aerylamide 显示文摘 | Paulsson B kotova N Grawe J | 2003 | Mutat Res2003，535，1： | 1 |
| 13 | Ethylnitrosourea-induced mutation in mice leads to the expression of a novel protein in the eye and to dominant cataracts 显示文摘 | Graw J Klopp N Loster J | 2001 | Genetics2001，157，3： | 1 |
| 14 | Survey of the applications, properties and technology of crosslinking emulsion ( Ⅱ )显示文摘 | Bufkin B G Grawe J T | 1978 | J Coat Technol1978，50，644： | 1 |
| 15 | Genetic aspects of embryonic eye development in vertebrates 显示文摘 | | 1996 | Dev Genet1996，18，： | 1 |
| 16 | Survey of the applications, properties, and technology of crosslinking emulsions 显示文摘 | Grawe J R Bufkin B G | 1978 | J Coat Technol1978，50，： | 1 |
| 17 | Logistics Service Providers and Their Customers: Gaining Commit- ment Through Organizational Implants显示文摘 | Scott J Grawe Patricia J Daugherty Rajiv P Dant | 2012 | Journal of Busi- ness Logistics2012，33，1： | 1 |
| 18 | Logistics Innovation: A Literature-based Conceptual Framework 显示文摘 | GRAWE S J | 2009 | The International Journal of Logistics Management2009，20，3： | 1 |
| 19 | Congenital hereditary cataracts 显示文摘 | Graw J | 2004 | Int J Dev Biol2004，48，： | 1 |
| 20 | V76D mutation in a conserved γD- crystallin region leads to dominant cataracts in mice显示文摘 | Graw J Loster J Soewarto D | 2002 | Mamm Genome2002，13，8： | 1 |
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