|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | MR with Gd-EOB-DTPA in assessment of liver nodules in cirrhotic patients显示文摘To date the imaging diagnosis of liver lesions is based mainly on the identification of vascular features, which are typical of overt hepatocellular carcinoma(HCC), but the hepatocarcinogenesis is a complex and multistep event during which, a spectrum of nodules develop within the liver parenchyma, including benign small and large regenerative nodule(RN), low-grade dysplastic nodule(LGDN), high-grade dysplastic nodule(HGDN), early HCC, and well differentiated HCC. These nodules may be characterised not only on the basis of their respective different blood supplies, but also on their different hepatocyte function. Recently, in liver imaging the introduction of hepatobiliary magnetic resonance imaging contrast agent offered the clinicians the possibility to obtain, at once, information not only related to the vascular changes of liver nodules but also information on hepatocyte function. For this reasons this new approach becomes the most relevant diagnostic clue for differentiating low-risk nodules(LGDN-RN) from highrisk nodules(HGDN/early HCC or overt HCC) and consequently new diagnostic algorithms for HCC have been proposed. The use of hepatobiliary contrast agents is constantly increasing and gradually changing the standard of diagnosis of HCC. The main purpose of this review is to underline the added value of Gd-EOB-DTPA in early-stage diagnoses of HCC. We also analyse the guidelines for the diagnosis and management of HCC, the key concepts of HCC development, growth and spread and the imaging appearance of precursor nodules that eventually may transform into overt HCC. | Riccardo Inchingolo Riccardo Faletti Luigi Grazioli Eleonora Tricarico Marco Gatti Anna Pecorelli Davide Ippolito | 2018 | World Journal of Hepatology2018，10，7： | 37 |
| 2 | Antidiabetic therapy and increased risk of hepatocellular carcinoma in chronic liver disease显示文摘AIM:To explore the association between hepatocellular carcinoma(HCC) and type 2 diabetes mellitus, describe the temporal relations between the onset of diabetes and the development of HCC and evaluate the possible effects of antidiabetic therapy on HCC risk.METHODS:We recruited 465 HCC patients, 618 with cirrhosis and 490 control subjects.We evaluated the odds ratio(OR) for HCC by univariate and multivariate analysis.Moreover, OR for HCC in diabetic subjects treated with insulin or sulphanylureas and with metformin were calculated.RESULTS:The prevalence of diabetes mellitus was 31.2% in HCC, 23.3% in cirrhotic patients and 12.7% in the Control group.By univariate and multivariate analysis, the OR for HCC in diabetic patients were respectively 3.12(CI 2.2-4.4, P < 0.001) and 2.2(CI 1.2-4.4, P = 0.01).In 84.9% of cases, type 2 diabetes mellitus was present before the diagnosis of HCC.Moreover, we report an OR for HCC of 2.99(CI 1.34-6.65, P = 0.007) in diabetic patients treated with insulin or sulphanylureas, and an OR of 0.33(CI 0.1-0.7, P = 0.006) in diabetic patients treated with metformin.CONCLUSION:Our study confi rms that type 2 diabetes mellitus is an independent risk factor for HCC and pre-exists in the majority of HCC patients.Moreover, in male patients with type 2 diabetes mellitus, our data shows a direct association of HCC with insulin and sulphanylureas treatment and an inverse relationship with metformin therapy. | Valter Donadon Massimiliano Balbi Michela Ghersetti Silvia Grazioli Antonio Perciaccante Giovanni Della Valentina Rita Gardenal Maria Dal Mas Pietro Casarin Giorgio Zanette Cesare Miranda | 2009 | World Journal of Gastroenterology2009，15，20： | 23 |
| 3 | Recent advances in non-invasive magnetic resonance imaging assessment of hepatocellular carcinoma显示文摘Magnetic resonance(MR) imaging of the liver is an important tool for the detection and characterization of focal liver lesions and for assessment of diffuse liver disease,having several intrinsic characteristics,represented by high soft tissue contrast,avoidance of ionizing radiation or iodinated contrast media,and more recently,by application of several functional imaging techniques(i.e.,diffusion-weighted sequences,hepatobiliary contrast agents,perfusion imaging,magnetic resonance(MR)-elastography,and radiomics analysis). MR functional imaging techniques are extensively used both in routine practice and in the field of clinical and pre-clinical research because,through a qualitative rather than quantitative approach,they can offer valuable information about tumor tissue and tissue architecture,cellular biomarkers related to the hepatocellular functions,or tissue vascularization profiles related to tumor and tissue biology. This kind of approach offers in vivo physiological parameters,capable of evaluating physiological and pathological modifications of tissues,by the analysis of quantitative data that could be used in tumor detection,characterization,treatmentselection,and follow-up,in addition to those obtained from standard morphological imaging. In this review we provide an overview of recent advanced techniques in MR for the diagnosis and staging of hepatocellular carcinoma,and their role in the assessment of response treatment evaluation. | Davide Ippolito Riccardo Inchingolo Luigi Grazioli Silvia Girolama Drago Michele Nardella Marco Gatti Riccardo Faletti | 2018 | World Journal of Gastroenterology2018，24，23： | 13 |
| 4 | Giardia lamblia infection in patients with irritable bowel syndrome and dyspepsia:A prospective study显示文摘瞄准:评估兰伯氏贾第虫的流行(G。兰氏鞭毛虫属) 在有急躁的肠症候群(IBS ) 和消化不良并且到的病人的感染证实哪个是最精确的测试在这个背景诊断感染。方法:连续地由于 IBS 或消化不良的症状在 2002 年 1 月和 2003 年 12 月之间第一次出席了门诊病人肠胃病学诊所的 137 个病人被招募。所有病人经历了临床的评估,第一步的 haematology 和化学测试,为乳糜泻的血清学试金, lactose-H (2 ) 呼吸测试,腹的 ultrasonography,和 esophagogastroduodenoscopy。Helicobacter pylori 地位被评估。在有比 45 年旧的 IBS 的症状的病人,结肠镜检查也被执行。在所有病人,十二指肠的活体检视和凳子样品为 G 的 trophozoites 和包囊被检验。由几个方法的兰氏鞭毛虫属。结果:G。兰氏鞭毛虫属在 9 个病人被识别。下列诊断也被做:IBS (100/137, 73%) ,机能性消化不良(62/137, 45%) ,器官的消化不良(33/137, 24%) ,并且乳糖不耐(75/137, 55%) 。一个重要协会在贾第虫病和 H pylori 感染之间被发现(c2=6.632, OR=12.4, CI=1.5-68.1 ) 。没有症状,可靠地允许贾第虫病的识别。当十二指肠的活体检视的组织学的检查显示了低敏感时,在十二指肠的活体检视和凳子样品考试的寄生虫的直接搜索在所有情况中给了一致结果(例如, 22.2%) 。结论:在这个连续系列, G 的诊断。兰氏鞭毛虫属感染与 IBS 和消化不良说明了 6.5% 病人。如果凳子样品检查被执行,为贾第虫病的诊断的十二指肠的活体检视可能是不必要的。 | Barbara Grazioli Giovanni Matera Costanza Laratta Giuseppina Schipani Giovanni Guarnieri Ester Spiniello Maria Imeneo Andrea Amorosi Alfredo Focà Francesco Luzza | 2006 | World Journal of Gastroenterology2006，12，12： | 4 |
| 5 | Gadoxetic acid magnetic-enhanced resonance imaging in the diagnosis of cholangiocarcinoma显示文摘The use of liver magnetic resonance imaging is increasing thanks to itsmultiparametric sequences that allow a better tissue characterization, and the useof hepatobiliary contrast agents. This review aims to evaluate gadoxetic acidenhanced magnetic resonance imaging in the diagnosis and staging ofcholangiocarcinoma and its different clinical and radiological classificationsproposed in the literature. We also analyze the epidemiology, risk factors incorrelation with clinical findings and laboratory data. | Riccardo Inchingolo Cesare Maino Marco Gatti Eleonora Tricarico Michele Nardella Luigi Grazioli SandroSironi Davide Ippolito Riccardo Faletti | 2020 | World Journal of Gastroenterology2020，26，29： | 4 |
| 6 | Colon capsule endoscopy:What we know and what we would like to know显示文摘Colonoscopy is usually perceived as an invasive and potentially painful procedure,being also affected by a small,but definite,risk of major complications(cardiopulmonary complications,perforation,hemorrhage)and even mortality.To improve both acceptability and safety,Pill Cam Colon Capsule Endoscopy(CCE)(Given Imaging Ltd,Yoqneam,Israel)has been developed.CCE represents a non-invasive technique that is able to explore the colon without sedation and air insufflation.The Second Generation of Colon Capsule Endoscopy(Pill Cam Colon 2)(CCE-2)was proven to be an accurate tool to detect colonic neoplastic lesions when used in average risk individuals.To date,the evidence supports the use of CCE-2 in case of colonoscopy failure,in patients unwilling to perform colonoscopy and when colonoscopy is contraindicated.Other potential applications,such as colorectal cancer screening or diagnostic surveillance ofinflammatory bowel disease need to be clarified.In this paper,the current'state of the art',potential application of CCE and future needs are evaluated. | Cristiano Spada Federico Barbaro Gianluca Andrisani Leonardo Minelli Grazioli Cesare Hassan Isabella Costamagna Mariachiara Campanale Guido Costamagna | 2014 | World Journal of Gastroenterology2014，20，45： | 2 |
| 7 | Quantitative analysis of contrast-enhanced ultrasonography of the bowel wall can predict disease activity in inflammatory bowel disease显示文摘 | Laura Romanini Matteo Passamonti Mario Navarria Francesco Lanzarotto Vincenzo Villanacci Grazioli Luigi Fabrizio Calliada Roberto Maroldi | 2014 | European Journal of Radiology2014，，： | 2 |
| 8 | Diagnostic Performance and Description of Morphological Features of Focal Nodular Hyperplasia in Gd-EOB-DTPA-Enhanced Liver Magnetic Resonance Imaging: Results of a Multicenter Trial显示文摘 | Christoph J. Zech Luigi Grazioli Josy Breuer Maximilian F. Reiser Stefan O. Schoenberg | 2008 | Investigative Radiology2008，，7： | 2 |
| 9 | A further step in the evolution of rabbit hemorrhagic disease virus: the appearance of the first consistent antigenic variant显示文摘 | CAPUCCI L FALLACARA F GRAZIOLI S | 1998 | Virus Res1998，58，12： | 1 |
| 10 | Hepatocellular adenoma:Muitiphasic CT and histopathologic findings in 25 pattents显示文摘 | Foderle MP Grazioli L | 2000 | Radiology2000，214，3： | 1 |
| 11 | Focal nodular hyperplasi-a:CT findings with emphasis on multiplasia helical CT in 78 patients显示文摘 | Brancatelli G Federle MP Grazioli L | 2001 | Radiology2001，219，1： | 1 |
| 12 | Enhancement and safety of iomeprol-400 and iodixanol-320 in patients un- dergoing 19,abdominal muhidetector CT显示文摘 | Romano L Grazioli L Bonomo L | 2009 | Br J Radiol2009，82，975： | 1 |
| 13 | Large regenerative nodules in BuddChiari syndrome and other vascular disorders of the liver:CT and MR imaging findings with clinicopathologic correlation显示文摘 | Brancatelli G Federle M P Grazioli L | 2002 | AJR2002，178，4： | 1 |
| 14 | MR Imaging of hepatocellular adenomas and differential diagnosis dilemma 显示文摘 | Grazioli L Olivetti L Mazza G | 2013 | Int J Hepatol2013，2013，37： | 1 |
| 15 | Focal nodular hyperplasia: morphologic and functional information from MR imaging with gadobenate dimeglumine 显示文摘 | Grazioli L Morana G Federle MP etal | 2001 | Radiology2001，221，3： | 1 |
| 16 | A further step in the evolution of rabbit hemorrhagic disease virus: the appearance of the first consistent antigenic variant显示文摘 | Lorenzo Capucci Francesca Fallacara Santina Grazioli Antonio Lavazza Maria Lodovica Pacciarini Emiliana Brocchi | 1998 | Virus Research1998，，1： | 1 |
| 17 | Antenatal and postnatal ultrasound in the evaluationof the risk of vesicoureteral re- flux 显示文摘 | Grazioli S Parvex P Laura Merlini | 2010 | Pediatr Nephrol2010，25，： | 1 |
| 18 | Diagnostic performance and description of morphological features of focal nodular hyper plasia in Gd-EOB-DTPA-enhanced liver magnetic resonance im- aging: results of a multieenter trial显示文摘 | Zech C J Grazioli L Breuer J | 2008 | Invest Radiol2008，43，7： | 1 |
| 19 | Fraud Detection: Deception and Intentionality in Cognition Accounting显示文摘 | Johnson P E Grazioli S Jamal K | 1993 | Organization and Society1993，，5： | 1 |
| 20 | The role of cognitive vulnerability and stress in the prediction of postpartum depressive symptomatology显示文摘 | Grazioli R Terry DJ | 2000 | Br J Clin Psychol2000，39，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员