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| 1 | Sharing Clinical Trial Data: A Proposal from the International Committee of Medical Journal Editors显示文摘The International Committee of Medical Journal Editors (ICMJE) believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk.In a growing consensus,many funders around the world-foundations,government agencies,and industry-now mandate data sharing.Here,we outline ICMJE's proposed requirements to help meet this obligation.We encourage feedback on the proposed requirements.Anyone can provide feedback at www.icmje.org by April 18,2016. | Darren B Taichman Joyce Backus Christopher Baethge Howard Bauchner Peter W de Leeuw Jeffrey M Drazen John Fletcher Frank Frizelle Irish Groves Abraham Haileamlak Astrid James Christine Laine Larry Peiperl Anja Pinborg Peush Sahni Si-Nan Wu | 2016 | Chinese Medical Journal2016，，2： | 20 |
| 2 | The Relevance of Pharmacopeial Particulate Matter Limit Tists显示文摘 | Grove M J De Malka S R | 1976 | Develop Commun1976，2，3： | 1 |
| 3 | Analysis of CFTR folding anddegradation in transiently transfected cells显示文摘 | Grove DE Rosser MF Watkins RL ef al | 2011 | Methods Mol Biol2011，741，： | 1 |
| 4 | An International Sur- vey-based Algorithm for the Pharmacologic Treatment of Irrita- bility in Huntington's Disease显示文摘 | Groves M Van DE Anderson K | 2011 | PLoS Curr2011，3，： | 1 |
| 5 | Breath Biopsy^(®) to Identify Exhaled Volatile Organic Compounds Biomarkers for Liver Cirrhosis Detection显示文摘Background and Aims:The prevalence of chronic liver dis-ease in adults exceeds 30%in some countries and there is significant interest in developing tests and treatments to help control disease progression and reduce healthcare burden.Breath is a rich sampling matrix that offers non-invasive so-lutions suitable for early-stage detection and disease moni-toring.Having previously investigated targeted analysis of a single biomarker,here we investigated a multiparametric approach to breath testing that would provide more robust and reliable results for clinical use.Methods:To identify can-didate biomarkers we compared 46 breath samples from cir-rhosis patients and 42 from controls.Collection and analysis used Breath Biopsy OMNI™,maximizing signal and contrast to background to provide high confidence biomarker detec-tion based upon gas chromatography mass spectrometry(GC-MS).Blank samples were also analyzed to provide de-tailed information on background volatile organic compounds(VOCs)levels.Results:A set of 29 breath VOCs differed significantly between cirrhosis and controls.A classification model based on these VOCs had an area under the curve(AUC)of 0.95±0.04 in cross-validated test sets.The seven best performing VOCs were sufficient to maximize classifica-tion performance.A subset of 11 VOCs was correlated with blood metrics of liver function(bilirubin,albumin,prothrom-bin time)and separated patients by cirrhosis severity using principal component analysis.Conclusions:A set of seven VOCs consisting of previously reported and novel candidates show promise as a panel for liver disease detection and mon-itoring,showing correlation to disease severity and serum biomarkers at late stage. | Giuseppe Ferrandino Giovanna De Palo Antonio Murgia Owen Birch Ahmed Tawfike Rob Smith Irene Debiram-Beecham Olga Gandelman Graham Kibble Anne Marie Lydon Alice Groves Agnieszka Smolinska Max Allsworth Billy Boyle Marc P.van der Schee Michael Allison Rebecca C.Fitzgerald Matthew Hoare Victoria K.Snowdon | 2023 | Journal of Clinical and Translational Hepatology2023，11，3： | 1 |
| 6 | Cerebral palsy among children born after in vitro fertilization:the role of preterm delivery a population-based,cohort study显示文摘 | Hvidtjorn D Grove J Schendel DE | 2006 | Pediatrics2006，118，2： | 1 |
| 7 | Cerebral palsy among children born after in vitro fertilization : the role of preterm delivery : a popula- tion-based cohort study 显示文摘 | Hvidtjrn D Grove J Sehendel DE | 2006 | Pediatrics2006，118，2： | 1 |
| 8 | Daly AK detection and characterization of novel polymorphisms in the CYP2E1 gene 显示文摘 | Fairbrother KS Grove J de Waziers I | 1998 | Pharmacogenetics1998，8，： | 1 |
| 9 | Rheological characterization of self-emusifying drug oil/surfaetant systems 显示文摘 | GROVE MJ DE GALINDEA DA | 1976 | Acta Pharrn Suec1976，13，4： | 1 |
| 10 | Tumour necrosis factor - alpha promoter polymorphisms in primary biliary cirrhosis 显示文摘 | Jones DE Watt FE Grove J | 1999 | J Hepatol1999，30，2： | 1 |
| 11 | The self-emulsifying action of mixed surfactants in oil显示文摘 | GROVES MJ DE GALINDEZ DA | 1976 | Acta Pharm Suec1976，13，4： | 1 |
| 12 | Analysis of CFTR folding and degradation in transiently transfected cells显示文摘 | Grove DE Rosser MF Watkins RL | 2011 | Methods Mol Biol2011，741，： | 1 |
| 13 | Cerebral palsy among children born after in vitro fertilization:the role of preterm delivery-a population-based,cohort study显示文摘 | Hvidtjrn D Grove J Schendel DE | | 0，，02： | 1 |
| 14 | Cerebral palsy among children born after fertilization the role of preterm delivery apopulation -based cohort study 显示文摘 | Hvidtjrn D Grove J Schendel DE | 2006 | Pediatrics2006，118，2： | 1 |
| 15 | The Relevance of pharmacopcial particulate matter limit tests显示文摘 | Grove MJ De Malke SR | 1976 | Drug Develop Commun1976，2，3： | 1 |
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