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| 1 | Liver cystic echinococcosis and human host immune and autoimmune follow-up:A review显示文摘Cystic echinococcosis(CE) is an infectious disease caused by the larvae of parasite Echinococcus granulosus(E.granulosus).To successfully establish an infection,parasite release some substances and molecules that can modulate host immune functions,stimulating a strong anti-inflammatory reaction to carry favor to host and to reserve self-survival in the host.The literature was reviewed using MEDLINE,and an open access search for immunology of hydatidosis was performed.Accumulating data from animal experiments and human studies provided us with exciting insights into the mechanisms involved that affect all parts of immunity.In this review we used the existing scientific data and discuss how these findings assisted with a better understanding of the immunology of E.granulosus infection in man.The aim of this study is to point the several facts that challenge immune and autoimmune responses to protect E.granulosus from elimination and to minimize host severe pathology.Understanding the immune mechanisms of E.granulosus infection in an intermediate human host will provide,we believe,a more useful treatment with immunomodulating molecules and possibly better protection from parasitic infections.Besides that,the diagnosis of CE has improved due to the application of a new molecular tool for parasite identification by using of new recombinant antigens and immunogenic peptides.More studies for the better understanding of the mechanisms of parasite immune evasion is necessary.It will enable a novel approach in protection,detection and improving of the host inflammatory responses.In contrast,according to the 'hygiene hypothesis',clinical applications that decrease the incidence of infection in developed countries and recently in developing countries are at the origin of the increasing incidence of both allergicand autoimmune diseases.Thus,an understanding of the immune mechanisms of E.granulosus infection is extremely important. | Nikica M Grubor Katica D Jovanova-Nesic Yehuda Shoenfeld | 2017 | World Journal of Hepatology2017，9，30： | 8 |
| 2 | Cystic lymphangioma of the pancreas显示文摘Lymphangioma of the pancreas is an extremely rare benign tumour of lymphatic origin,with fewer than 60 published cases. Histologically,it is polycystic,with the cysts separated by thin septa and lined with endothelial cells. Though congenital,it can affect all age groups,and occurs more frequently in females. Patients usually present with epigastric pain and an associated palpable mass. Complete excision is curative,even though,depending on the tumour location,surgery may be simple or involve extensive pancreatic resection and anastomoses. The authors present a 49-year-old woman in whom a polycystic septated mass,35 mm x 35 mm in size,was discovered by ultrasonography (US) in the body of the pancreas during investigations for epigastric pain and nausea. At surgery,a well circumscribed polycystic tumor was completely excised,with preservation of the pancreatic duct. The postoperative recovery was uneventful. Histology confirmed a microcystic lymphangioma of the pancreas. Immunohistochemistry showed cystic endothelial cells reactivity to factor Ⅷ -RA (++),CD31 (+++) and CD34 (-). Postoperatively,abdominal pain disappeared and the patient remained symptomfree for 12 mo until now. Although extremely rare,lymphangioma of the pancreas should be taken into consideration as a differential diagnosis of a pancreatic cystic lesion,especially in women. | Radoje B Colovic Nikica M Grubor Marjan T Micev Henry Dushan E Atkinson Vitomir I Rankovic Mihajlo M Jagodic | 2008 | World Journal of Gastroenterology2008，14，44： | 6 |
| 3 | Perigastric extraskeletal Ewing's sarcoma: A case report显示文摘Ewing's sarcoma (ES) is a neoplasm of undifferentiated small round cells, which occurs in the bones and deep soft tissues of children and adolescents. We present a rare case of a 44-year-old woman with gastric ES presenting with epigastric pain and weight loss. Ultrasound and computed tomography scans indicated a solid/cystic mass in the pancreatic tail. At laparotomy, the tumor was found attached to the posterior surface of the stomach, completely free from the pancreas, with no lymphadenopathy or local metastases. The polynodal, partly pseudocystic, dark-red soft tumor was excised. Histopathology revealed an anaplastic small-round-cell tumor with strong membranous CD99 immunoexpression. Additionally, there was patchy immunostaining for S-100 protein, vimentin, protein gene product (PGP) 9.5 and neuron-specifi c enolase, and weak focal CD117 cytoplasmic immunoreactivity. The patient had no adjuvant chemotherapy; her postoperative recovery was uneventful, and she remains symptom-free, and without any sign of recurrence at 20 mo. To the best of our knowledge, this is only the third ever case of gastric ES. | Radoje B Colovic Nikica M Grubor Marjan T Micev Slavko V Matic Henry Dushan Edward Atkinson Stojan M Latincic | 2009 | World Journal of Gastroenterology2009，15，2： | 2 |
| 4 | Necrosis of the Duodenum Resulting from Acute Necrotising Pancreatitis and Treated with Complete Duodenopancreatectomy显示文摘 | Colovic R Grubor N Radak V | 2005 | Srp Arh Celok Lek2005，133，1112： | 1 |
| 5 | Two synchronous somatostatinomas of the duodenum and pancreatic head in one patient显示文摘Somatostatinomas are extremely rare neuroendocrine tumors of the gastrointestinal tract,f irst described in the pancreas in 1977 and in the duodenum in 1979.They may be functional and cause somatostatinoma or inhibi-tory syndrome,but more frequently are non-functioning pancreatic endocrine tumors that produce somatostatin alone.They are usually single,malignant,large lesions,frequently associated with metastases,and generally with poor prognosis.We present the unique case of a 57-year-old woman with two synchronous non-function-ing somatostatinomas,one solid duodenal lesion and one cystic lesion within the head of the pancreas,that were successfully resected with a pylorus-preserving Whipple's procedure.No secondaries were found in the liver,or in any of the removed regional lymph nodes.The patient had an uneventful recovery,and remains well and symptom-free at 18 mo postoperatively.This is an extremely rare case of a patient with two synchro-nous somatostatinomas of the duodenum and the pancreas.The condition is discussed with reference to the literature. | Radoje B olovi Slavko V Mati Marjan T Micev Nikica M Grubor Henry Dushan Atkinson Stojan M Latini | 2009 | World Journal of Gastroenterology2009，15，46： | 1 |
| 6 | Optical wireless communications forbroadband access in home area networks 显示文摘 | LANGER KD GRUBOR J BOUCHET O | 2008 | ICTON 2008 : Proceedings2008，4，： | 1 |
| 7 | Risk factors for permanent injury of inferior alveolar and lingual nerves during third molar surgery显示文摘 | Nguyen E Grubor D Chandu A | 2014 | J Oral Maxillofae Surg2014，72，12： | 1 |
| 8 | Abdominal neurenteric cyst显示文摘Neurenteric cysts are extremely rare congenital anomalies,often presenting in the first 5 years of life,and are caused by an incomplete separation of the notochord from the foregut during the third week of embryogenesis. They are frequently accompanied with spinal or gastrointestinal abnormalities,but the latter may be absent in adults. Although usually located in the thorax,neurenteric cysts may be found along the entire spine. We present a 24-year-old woman admitted for epigastric pain,nausea,vomiting,low grade fever and leucocytosis. She underwent cystgastrostomy for a loculated cyst of the distal pancreas at the age of 4 years,which recurred when she was at the age of 11 years. Ultrasound and computer tomograghy(CT) scan revealed a 16 cm × 15 cm cystic mass in the body and tail of pancreas,with a 6-7 mm thickened wall. Laboratory data and chest X-ray were normal and spinal radiographs did not show any structural abnormalities. The patient underwent a complete cyst excision,and after an uneventful recovery,remained symptom-free without recurrence during the 5-year follow-up. The cyst was found to contain 1200 mL of pale viscous fluid. It was covered by a primitive single-layered cuboidal epithelium,along with specialized antral glandular parenchyma and hypoplastic primitive gastric mucosa. Focal glandular groups resemblingthose of the body of the stomach were also seen. In addition,ciliary respiratory epithelium,foci of squamous metaplasia and mucinous glands were present. The wall of the cyst contained a muscular layer,neuroglial tissue with plexogenic nerve fascicles,Paccini corpuscle-like structures,hyperplastic neuroganglionar elements and occasional psammomatous bodies,as well as fibroblast-like areas of surrounding stroma. Cartilagenous tissue was not found in any part of the cyst. Immunohistochemistry confirmed the presence of neurogenic elements marked by S-100,GFAP,NF and NSE. The gastric epithelium showed mostly CK7 and EMA immunoexpression,and the respiratory epithelium revealed a CK8 and CK18 immunoprofile without CK 10/13 positive elements,though neither CEA or AFP positive cells were found. To our knowledge,this is the first reported case of an abdominally located neurenteric cyst with no associated spinal anomalies. | Radoje olovi Marjan Micev Miodrag Jovanovi Slavko Mati Nikica Grubor Henry Dushan E Atkinson | 2008 | World Journal of Gastroenterology2008，14，23： | 1 |
| 9 | Regulation of surfactant protein and defensin mRNA expression in cultured ovine type 11 pneumocytes by aU-trans retinoic acid and VEGF 显示文摘 | Grubor B Meyerholz DK Lazic T | 2006 | Int J Exp Pathol2006，87，5： | 1 |
| 10 | Genetic heterogeneity of diffuse large B-cell lymphoma显示文摘 | Zhang J Grubor V Love C L | | 0，，： | 1 |
| 11 | The incidence of mandibular third molar impactions in different skeletal face types显示文摘 | Breik O Grubor D | | 0，，4： | 1 |
| 12 | The evaluation of impact of BPH surgical treatment with the open prostatectomy and transurethral resection of the prostate methods on the quality of life显示文摘 | Milicevic S Grubor P Lucic N | 2011 | Med Arh2011，65，5： | 1 |
| 13 | Treatment of Achilles tendon rupture using dif- ferent methods显示文摘 | Grubor P Grubor M | 2012 | Vojnosaah Pregl2012，69，8： | 1 |
| 14 | Broadband information broadcasting using LED-based interior lighting显示文摘 | GRUBOR J RANDEL S LANGER K D | 2008 | Lightwave Technology2008，26，24： | 1 |
| 15 | Broadband informa-tion using LED-based interior lighting显示文摘 | GRUBOR J RANDEL S LANGER K D | 2008 | IEEE Journal of Light-wave Technology2008，26，24： | 1 |
| 16 | Effect of cold acclimation of the antioxidant defense system of two larval Lepidoptera (Noctuidae)显示文摘 | GRUBOR L G BLOCK W TELESMANIC M | 1997 | Archives of Insect Biochemistry and Physiology1997，36，1： | 1 |
| 17 | Developmental expression and distribution of sheep beta-defensin-2 显示文摘 | Heyerholz D K Gallup J M Grubor B | 2004 | DevComp Immunol2004，28，： | 1 |
| 18 | The incidence of mandibular third molarim- pactions in different skeletal ace types 显示文摘 | Breik O Grubor D | 2008 | Aust Dent J2008，53，： | 1 |
| 19 | Broad- band Information Broadcasting Using LED-Based Interior Lighting 显示文摘 | Grubor J Randel S Langer K D Joachim W W | 2008 | IEEE Journal of Lightwave Technology2008，26，24： | 1 |
| 20 | Genetic heteroge- neity of diffuse large Prcell lymphoma显示文摘 | Zhang J Grubor V Love CL | 2013 | Proc Natl Acad Sci U S A2013，110，4： | 1 |
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