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| 1 | Effect of early enteral nutrition on postoperative nutritional status and immune function in elderly patients with esophageal cancer or cardiac cancer显示文摘Objective: To explore the effect of early enteral nutrition (EN) on postoperative nutritional status, intestinal permeability, and immune function in elderly patients with esophageal cancer or cardiac cancer. Methods: A total of 96 patients with esophageal cancer or cardiac cancer who underwent surgical treatment in our hospital from June 2007 to December 2010 were enrolled in this study. They were divided into EN group (n=50) and parenteral nutrition (PN) group (n=46) based on the nutrition support modes. The body weight, time to first flatus/defecation, average hospital stay, complications and mortality after the surgery as well as the liver function indicators were recorded and analyzed. Peripheral blood samples were collected on the days 1, 4 and 7 after surgery. The plasma diamine oxidase (DAO) activity and D-lactate level were determined to assess the intestinal permeability. The plasma endotoxin levels were determined using dynamic turbidimetric assay to assess the protective effect of EN on intestinal mucosal barrier. The postoperative blood levels of inflammatory cytokines and immunoglobulins were determined using enzyme- linked immunosorbent assay (ELISA). Results: After the surgery, the time to first flatus/defecation, average hospital stay, and complications were significantly less in the EN group than those in the PN group (P<0.05), whereas the EN group had significantly higher albumin levels than the PN group (P<0.05). On the 7th postoperative day, the DAO activity, D-lactate level and endotoxin contents were significantly lower in the EN group than those in the PN group (all P<0.05). In addition, the EN group had significantly higher IgA, IgG, IgM, and CD4 levels than the PN group (P<0.05) but significantly lower IL-2, IL-6, and TNF-α levels (P<0.05). Conclusions: In elderly patients with esophageal cancer or cardiac cancer, early EN after surgery can effectively improve the nutritional status, protect intestinal mucosal barrier (by reducing plasma endoxins), and enhance the immune | Guiping Yu Guoqiang Chen Bin Huang Wenlong Shao Guangqiao Zeng | 2013 | Chinese Journal of Cancer Research2013，25，3： | 67 |
| 2 | Translational medicine:What is in a name from the perspective of Chinese clinicians?显示文摘Translational medicine is an emerging medical practice that involves multidisciplinary collaborations to bridge between basic sciences and clinical use,aiming at enhancing patient care and preventive measures.As it suggests for most,basic scientists in particular,the term 'translational medicine' | ZENG GuangQiao ZHONG NanShan | 2011 | Science China(Life Sciences)2011，54，12： | 6 |
| 3 | Early screening of lung cancers:an effort arduous but worthwhile显示文摘Cancers are a concerning health catastrophe worldwide that may become the end of lifetime for many of us—they overwhelmingly exhaust medical resources,lead to huge economic burdens,and separate people from their beloved ones.Fewer and fewer insurance agencies are willing to include primary cancers on their general health insurance plan,just because cancers have been so flummoxingly | Chu Pei Lawrence Grouse Guangqiao Zeng | 2015 | Chinese Journal of Cancer Research2015，27，6： | 1 |
| 4 | Use of endoscopic ultrasound-based techniques in tumor of the guts and beyond显示文摘<正>Endoscopic techniques in gastroenterology have been developing rapidly over the past two decades.Advances in minimally invasive endoscopic techniques allow for the detection and treatment of more gastrointestinal(GI)diseases than ever.In a manner of speaking,the advent of miniature ultrasound device coupled with | Chu Pei Guangqiao Zeng | 2014 | Chinese Journal of Cancer Research2014，26，6： | 0 |
| 5 | Endobronchial ultrasound-guided transbronchial needle aspiration: unraveling myths of mass in the chest显示文摘<正>Lung cancer is one of the most common neoplasms worldwide and a major cause of cancer death.Rapid diagnosis and accurate staging for patients with suspected lung cancer are essential to appropriate treatment.However,many of submucosal or parabronchial intrapulmonary lesions are invisible by bronchoscopy despite their | Rui Wang Guangqiao Zeng | 2014 | Chinese Journal of Cancer Research2014，26，6： | 0 |
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