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| 1 | Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair显示文摘间充质的干细胞(MSC ) 为治疗各种各样的疾病有大潜力,特别那些与织物有关损坏包含有免疫力的反应。各种各样的研究证明了 MSC 在 vitro 并且在 vivo 是强烈抑制免疫力的。我们的最近的研究证明了那未刺激的 MSC 确实不能免疫力的抑制;他们与 TNF- 伪, IL-1 伪或 IL-1 尾与激活的淋巴细胞的上层清液,或与 IFN- 纬的联合在刺激之上变得 potently 抑制免疫力。这观察表明在某些情形下面,煽动性的 cytokines 能实际上变得抑制免疫力。我们证明在调停 MSC 的免疫力的抑制的机制有一个种类变化:由告知 cytokine 的老鼠 MSC 的免疫力的抑制被氮的氧化物调停(没有) 而由告知 cytokine 的人的 MSC 的免疫力的抑制通过 indoleamine 被执行 2, 3-dioxygenase (伊多语) 。在有煽动性的 cytokines 的刺激之上,另外,老鼠和人的 MSC 分泌几白血球 chemokines 显然服务与 MSC 吸引有免疫力的房间进最近,在哪儿不或伊多语被预言很活跃。因此,由煽动性的刺激 cytokine 的 MSC 的免疫力的抑制经由 chemokines 的一致行动发生并且免疫者禁止没有或伊多语由 MSC 生产了。因此,我们的结果在对待有免疫力的回答导致的织物损害关于调停 MSC 的免疫力的抑制并且为 MSC 的更好的申请的机制提供新奇信息。 | Yufang Shi Gangzheng Hu Juanjuan Su Wenzhao Li Qing Chen Peishun Shou Chunliang Xu Xiaodong Chen Yin Huang Zhexin Zhu Xin Huang Xiaoyan Han Ningxia Xie Guangwen Ren | 2010 | Cell Research2010，20，5： | 72 |
| 2 | Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know显示文摘Granulocyte 巨噬细胞刺激殖民地的因素(GM-CSF ) 是一个重要造血的生长因素和有免疫力的调节的人。GM-CSF 也在各种各样的传播白血球的功能的活动有深刻效果。它被许多房间类型在收到有免疫力的刺激之上包括 T 房间,巨噬细胞, endothelial 房间和成纤维细胞生产。尽管 GM-CSF 局部地被生产,它能以一种 paracrine 方式行动到在主人防卫提高他们的功能的成员传播 neutrophils,单核白血球和淋巴细胞。最近的集中的调查为它增加树枝状的房间(DC ) 成熟和功能以及巨噬细胞活动的能力作为一个有免疫力的助手在 GM-CSF 的应用程序上被集中。在经历化疗的癌症病人对待嗜中性白血球减少症临床上被使用,在在治疗期间的爱滋病病人,并且在在骨髓移植以后的病人。有趣地, GM-CSF-deficient 老鼠的造血的系统看起来正常;最重要的变化在一些特定的 T 房间回答。尽管 GM-CSF 的分子的克隆用 T 房间的 cDNA 图书馆被执行, T 房间在激活以后生产 GM-CSF,是众所周知的,在 T 房间功能上有在由 T 房间和它的效果的生产的这 cytokine 的系统的调查的缺乏。在这篇文章,我们将在 T 房间主要集中于 GM-CSF 的免疫生物学。 | Yufang Shi Catherine H Liu Arthur I Roberts Jyoti Das Guangwu Xu Guangwen Ren Yingyu Zhang Liying Zhang Zeng Rong Yuan Hung Sheng William Tan Gobardhan Das Satish Devadas | 2006 | Cell Research2006，16，2： | 22 |
| 3 | Nanocellulose:Extraction and application显示文摘Recently,nanocellulose and its applications gain high attraction in both research and industrial areas due to its attractive properties such as excellent mechanical properties,high surface area,rich hydroxyl groups for modification,and natural properties with 100%environmental friendliness.In this review,the background of nanocellulose originated from lignocellulosic biomass and the typical extraction methods and general applications are summarized,in which the nanocellulose extraction methods related to ball milling are mainly introduced.Also,an outlook on its future is given.It is expected to provide guidance on the effective extraction of nanocellulose from biomass and its most possible applications in the future. | Patchiya Phanthong Prasert Reubroycharoen Xiaogang Hao Guangwen Xu Abuliti Abudula Guoqing Guan | 2018 | Carbon Resources Conversion2018，1，1： | 17 |
| 4 | Ni/Al_2O_3 catalysts for CO methanation: Effect of Al_2O_3 supports calcined at different temperatures显示文摘The correlation between phase structures and surface acidity of Al2O3 supports calcined at different temperatures and the catalytic performance of Ni/Al2O3 catalysts in the production of synthetic natural gas(SNG) via CO methanation was systematically investigated. A series of 10 wt% NiO/Al2O3 catalysts were prepared by the conventional impregnation method, and the phase structures and surface acidity of Al2O3 supports were adjusted by calcining the commercial γ-Al2O3 at different temperatures(600–1200 C). CO methanation reaction was carried out in the temperature range of 300–600 C at different weight hourly space velocities(WHSV = 30000 and 120000 mL·g-1h-1) and pressures(0.1 and 3.0 MPa). It was found that high calcination temperature not only led to the growth in Ni particle size, but also weakened the interaction between Ni nanoparticles and Al2O3 supports due to the rapid decrease of the specific surface area and acidity of Al2O3 supports. Interestingly, Ni catalysts supported on Al2O3 calcined at 1200 C(Ni/Al2O3-1200) exhibited the best catalytic activity for CO methanation under different reaction conditions. Lifetime reaction tests also indicated that Ni/Al2O3-1200 was the most active and stable catalyst compared with the other three catalysts, whose supports were calcined at lower temperatures(600, 800 and 1000 C). These findings would therefore be helpful to develop Ni/Al2O3 methanation catalyst for SNG production. | Jiajian Gao Chunmiao Jia Jing Li Meiju Zhang Fangna Gu Guangwen Xu Ziyi Zhong Fabing Su | 2013 | Journal of Energy Chemistry2013，22，6： | 16 |
| 5 | Reaction decoupling in thermochemical fuel conversion and technical progress based on decoupling using fluidized bed显示文摘Thermochemical conversion of fuels via pyrolysis/carbonization,cracking,gasification and combustion has to involve a number of individual reactions called attribution reactions to form an intercorrelated reaction network for any conversion process.By separating one or some attribution reactions from the others to decouple their interactions existing in the reaction network,the so-called reaction decoupling enables a better understanding of the complex thermal conversion process and further the optimization of the conditions for attribution reactions as well as the entire conversion process to realize advanced performances.The dual bed conversion and two-stage conversion are the two representative types of fuel conversion technologies developed in recent years based on reaction decoupling.Many technical advantages have been proven for such decoupling fuel conversion technologies,such as poly-generation of products,low-cost production of high-grade products,elimination of undesirable products or pollutants,easy operation and control,and so on.The treated fuels with decoupling conversion technologies mainly include solid biomass and coal,as well as liquid petroleum oil.This paper is devoted to reiteration of the reaction decoupling concept and further to reviewing the research,developments and successful applications of several decoupling fuel conversion technologies of two such types by using fluidized bed as their major reactors. | Zhennan Han Sulong Geng Xi Zeng Shipei Xu a Ping An Jiguang Cheng Jun Yang Feng Li Suyi Zhang Miao Liu Guoqing Guan Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，2： | 8 |
| 6 | Two-fluid modeling of Geldart A particles in gas-solid micro-fluidized beds显示文摘The fluidizadon behavior of Geldart A particles in a gas-solid micro-fluidized bed was investigated by Eulerian-Eulerian numerical simulation.The commonly used Gidaspow drag model was tested first.The simulation showed that the predicted minimum bubbling velocities were significantly lower than the experimental data even when an extremely fine grid size(of approximately one particle diameter) was used.The modified Gibilaro drag model was therefore tested next.The predicted minimum bubbling velocity and bed voidage were in reasonable agreement with the experimental data available in literature.The experimentally observed regime transition phenomena from bubbling to slugging were also reproduced successfully in the simulations.Parametric studies indicated that the solid-wall boundary conditions had a significant impact on the predicted gas and solid flow behavior. | Xiaoxing Liu Chuanqiang Zhu Shujun Geng Meiqin Yao Jinhui Zhan Guangwen Xu | 2015 | Particuology2015，13，4： | 8 |
| 7 | Characterization and pilot scale test of a fluidized bed two-stage gasification process for the production of clean industrial fuel gas from low-rank coal显示文摘To utilize low rank coal efficiently,a fluidized bed two-stage(FBTS)gasification process,mainly consisting of a FB pyrolyzer and a transport FB(TFB)gasifier,has been proposed for the production of clean fuel gas.To verify the feasibility and technical features of this novel gasification technology,a pilot autothermal platform,with a treating capacity of 100 kg/h for coal,was designed and built up.By adopting a kind of lignite from Inner Mongolia,the running state and fuel gas quality were compared systematically under typical operational conditions.The results show that by keeping the reaction temperatures of pyrolyzer and gasifier at around 840C and 1000C,respectively,the corresponding tar content in fuel gas at the outlets of pyrolyzer and gasifier were 1127 mg/Nm3 and 365 mg/Nm3,reaching a high tar removal efficiency.Under the stable operation state,the volume fractions of CO,H2,CH4 and CO2 in fuel gas were 14.4%,8.3%,3.4%and 11.3%,respectively,and the corresponding higher heating value of fuel gas was about 1100 kcal/Nm3.Compared with the tar from pyrolyzer,the heavy oil fraction in tar from gasifier reduced significantly,while the light oil components increased sharply simultaneously,showing significant effect of catalytic reforming by hot char bed on tar removal. | Xi Zeng Fang Wang Zhennan Han Yanlin Sun Yanbin Cui Guangwen Xu | 2018 | Carbon Resources Conversion2018，1，1： | 8 |
| 8 | Suppressing secondary reactions of coal pyrolysis by reducing pressure and mounting internals in fixed-bed reactor显示文摘Pyrolysis of Shenmu coal was performed in fixed-bed reactors indirectly heated by reducing operating pressure and mounting internals in the reactor to explore their synergetic effects on coal pyrolysis. Mounting internals particularly designed greatly improved the heat transfer inside coal bed and raised the yield of tar production.Reducing pressure further facilitated the production of tar through its suppression of secondary reactions occurring in the reactor. The absolute increase in tar yield reached 3.33 wt% in comparison with the pyrolysis in the reactor without internals under atmospheric pressure. The obtained tar yield in the reactor with internals under reduced pressure was even higher than the yield of Gray–King assay. Through experiments in a laboratory fixed bed reactor, it was also clarified that the effect of reducing pressure is related to volatile release rate in pyrolysis. It did not obviously vary tar yield at pyrolysis temperatures below 600 °C, while the effect was evident at 650 and 700 °C but became limited again above 800 °C. Under reduced pressure the produced tar contained more aliphatics and phenols but less aromatics. | Shuai Cheng Dengguo Lai Zhen Shi Leisheng Hong Jianling Zhang Xi Zeng Shiqiu Gao Guangwen Xu | 2017 | Chinese Journal of Chemical Engineering2017，25，4： | 7 |
| 9 | Efficient gasification of wet biomass residue to produce middle caloric gas显示文摘Various process residues represent a kind of biomass resource already concentrated but containing water as much as 60 wt.%.These materials are generally treated as waste or simply combusted directly to generate heat.Recently,we attempted to convert them into middle caloric gas to substitute for natural gas,as a chemical or a high-rank gaseous fuel for advanced combustion utilities.Such conversion is implemented through dual fluidized bed gasification(DFBG).Concerning the high water content of the fuels,DFBG was suggested to accomplish either with high-efficiency fuel drying in advance or direct decoupling of fuel drying/pyrolysis from char gasification and tar/hydrocarbon reforming.Along with fuel drying, calcium-based catalyst can be impregnated into the fuel,without much additional cost,to increase the fuel’s gasification reactivity and to reduce tar formation.This article reports the Ca impregnation method and its resulting effects on gasification reactivity and tar suppression ability.Meanwhile, the principle of directly gasifying wet fuel with decoupled dual fluidized bed gasification(D-DFBG)is also highlighted. | Guangwen Xu Takahiro Murakami Toshiyuki Suda Hidehisa Tani Yutaka Mito | 2008 | Particuology2008，6，5： | 7 |
| 10 | Discrete and continuum modeling of granular flow in silo discharge显示文摘 | Tian Tian Jinglin Su Jinhui Zhan Shujun Geng Guangwen Xu Xiaoxing Liu | 2018 | Particuology2018，16，1： | 6 |
| 11 | Characteristics of gas-solid micro fluidized beds for thermochemical reaction analysis显示文摘Fuel conversion and clean energy reaction systems involve a variety of catalytic and non-catalytic gas-solid thermochemical reactions.A good understanding of the correct reaction mechanism and kinetics,as well as the profiles of reaction products,is of great significance to the development,design,and operation of such reaction systems.The micro fluidized bed reaction analysis provides an efficient and reliable method to acquire this essential information with low capital and operating costs,low energy consumption and enhanced safety.This paper provides an overview of the system and its characteristics for the micro fluidized bed reaction analyzer that has been well proven to be a reliable new approach as well as an instrument for characterizing various gas-solid thermochemical reactions. | Zhennan Han Junrong Yue Xi Zeng Jian Yu Fang Wang Shaozeng Sun Hong Yao Guangqian Luo Xuejing Liu Yining Sun Fu Ding Liangliang Fu Lei Shi Kangjun Wang Jiebin Yang Shaonan Wang Xueqing Chen Dingrong Bai Guangwen Xu | 2020 | Carbon Resources Conversion2020，3，1： | 6 |
| 12 | Modeling and analysis of oil shale refinery process with the indirectly heated moving bed显示文摘China is rich of oil shale as one of alternative fossil energy resources.The exploitation and utilization of oil shale are strategically important in alleviating the shortage of oil and gas resources in China.However,low utilization rate of raw material,low oil yield,and high content of heavy components in the oil are the main problems in current Fushun type oil shale refinery technology.An indirectly heated moving bed is developed to de-bottleneck Fushun type technology.The oil shale refinery process with the indirectly heated moving bed is modeled and simulated in this work.Based on the simulation,a techno-economic analysis is performed and compared with the conventional Fushun oil shale refinery process.Results show that:for a shale refinery of 3.0 Mt/y scale,375 t/h oil shale retorting requires 149.6 MW of heat,in which 60%of the heat is produced by combustion of the oil shale pyrolysis gas,while remaining 40%from the coal gasified gas.In consideration of investment and operation,the cost of product shale oil of the new process is 2636 CNY/t,which is 12%lower than that of the conventional Fushun refinery process.This benefit comes from higher utilization of raw material and oil yield of the new process.The competitive crude oil price of the indirectly heated moving bed refinery process is about 51$/bbl,while that of the Fushun refinery process is 58$/bbl.During 2017 year,the crude oil price fluctuates at around 50$/bbl,thus the new indirectly heated moving bed refinery process shows better economic competitiveness. | Huairong Zhou Shuai Zeng Siyu Yang Guangwen Xu Yu Qian | 2018 | Carbon Resources Conversion2018，1，3： | 5 |
| 13 | Characterization of char from high temperature fluidized bed coal pyrolysis in complex atmospheres显示文摘 | Mei Zhong Shiqiu Gao Qi Zhou Junrong Yue Fengyun Ma Guangwen Xu | 2016 | Particuology2016，14，2： | 5 |
| 14 | SCStore: Managing Scientific Computing Packages for Hybrid System with Containers显示文摘Managing software packages in a scientific computing environment is a challenging task, especially in the case of heterogeneous systems. It is error prone when installing and updating software packages in a sophisticated computing environment. Testing and performance evaluation in an on-the-fly manner is also a troublesome task for a production system. In this paper, we discuss a package management scheme based on containers. The newly developed method can ease the maintenance complexity and reduce human mistakes. We can benefit from the self-containing and isolation features of container technologies for maintaining the software packages among intricately connected clusters. By deploying the Super Computing application Strore(SCStore) over the WAN connected world-largest clusters, it proved that it can greatly reduce the effort for maintaining the consistency of software environment and bring benefit to achieve automation. | Wusheng Zhang Jiao Lin Weiping Xu Haohuan Fu Guangwen Yang | 2017 | Tsinghua Science and Technology2017，22，6： | 5 |
| 15 | Synthesis of texture-excellent mesoporous alumina using PEG1000 as structure-directing agent显示文摘By varying concentration of PEG1000 as a structure-directing agent,mesoporous alumina with excellent textural properties was synthesized.The prepared mesoporous alumina displays high thermal stability,as shown by its textural properties at different calcination temperatures of 600-850 °C.Characterization by SEM and TEM revealed that the added PEG surfactant induced the formation of petal-like alumina.XRD results clarified that all samples were amorphous and their peaks were around the peaks of γ-alumina.N_2 adsorption-desorption analysis showed that the prepared mesoporous alumina,if with PEG1000 in hydrolysis of aluminum isopropoxide,had excellent textural properties with large specific surface area,high pore volume and suitable pore size.The petal-like structure existing in the alumina samples improved their textural parameters,and the role and influential mechanism of PEG1000 were analyzed. | Kui Zhang Changming Li Jian Yu Shiqiu Gao Guangwen Xu | 2017 | Chinese Journal of Chemical Engineering2017，25，1： | 5 |
| 16 | Recent progress in tar removal by char and the applications:A comprehensive analysis显示文摘Tar catalytic removal by char is a promising technology for gasification process because of its porous structure,good catalytic activity,low cost,and easy to treatment after deactivation.To provide comprehensive information on the tar catalytic removal by char,this study focuses on the ongoing efforts and advances from fundamental researches to the industrial applications.The tar removal efficiency by char much depends on reaction conditions and char property,such as char origin,porous structure,the functional group on char surface,carbon structure,and AAEM components.The typical reaction kinetics,reaction mechanism,and the deactivation,will be introduced.Then,for the different gasification processes,the potential or typical applications of tar removal by char are discussed and compared.Finally,a comprehensive analysis and improvement in scaling up,commercializing tar removal technologies and integrating the gasification process,are also evaluated and analyzed in this review. | Xi Zeng Yasuaki Ueki Ryo Yoshiie Ichiro Naruse Fang Wang Zhennan Han Guangwen Xu | 2020 | Carbon Resources Conversion2020，3，1： | 5 |
| 17 | A displacement-relay videometric method for surface subsidence surveillance in unstable areas显示文摘When measuring the surface subsidence of unstable areas such as railroad beds and large construction fields, it is not practical to always find stable positions to install measurement instruments. Yet installing those instruments in unstable positions will cause measurement errors or even the complete failure of long-term subsidence surveillance. In this paper, the innovative concept and its method of 'displacement-relay videometrics' are proposed. With the method, a double-headed camera is designed, and two constraints, the 'fixation constraint' and the 'homologous constraint', are established to construct the displacement-relay measurement equations, which can concurrently give the subsidence of the points to be measured and the positions where the cameras are fixed. The method and its measurement system are thus capable of automatically measuring the surface subsidence under the condition that the cameras are mounted on unstable locations over long durations. Therefore, the method has the broad prospect of undertaking automatic, long-term and continuous measurement for surface subsidence in engineering projects such as railroad beds, bridges and the ground beds of tall buildings. The proposed method opens a new area that cameras can be mounted on unstable platform to make high accuracy measurements, which is of great significance for applications. | YU QiFeng JIANG GuangWen SHANG Yang XU Yong LIU XiaoLin FU SiHua GUAN BangLei ZHU XianWei | 2015 | Science China(Technological Sciences)2015，58，6： | 5 |
| 18 | Tandem fluidized bed elutriator——Pneumatic classification of coal particles in a fluidized conveyer显示文摘Coal moisture control (CMC) in coking process, which reduces coal moisture before loading the coal into the coke oven, allows substantial reduction in coking energy consumption and increase in coke productivity. The technology is seeking to integrate the coal classification, thus calling it the coal classifying moisture control (CCMC), to separate the fine and coarse coal fractions in the CMC process so that the downstream coal crushing can only treat the coarse fraction. CCMC adopts a reactor that integrates a fluidized bottom section and a pneumatic conveying top section. The present work investigates the pneumatic classification behavior in a laboratory CCMC reactor with such a configuration by removing the coal fraction below a given size (e.g., 3.0 mm) from a 0 to 20.0 mm coal feed. The results show that the coal classification were dominated by the gas velocity in the top conveying section, and the required gas velocity for ensuring the maximal degree of removing a fine coal fraction could be roughly predicted by the Richardson and Zaki equation. The effect of bottom fluidization on the performance of CCMC is also examined. | Zhouen Liu Yimin Xie Yin Wang Jian Yu Shiqiu Gao Guangwen Xu | 2012 | Particuology2012，10，5： | 4 |
| 19 | Development of highly active coated monolith SCR catalyst with strong abrasion resistance for low-temperature application显示文摘与 V 2 O 5-WO3/TiO2 被改变文件夹和涂层厚度准备。与独块巨石作比较与 100% V 2 O 5-WO3/TiO2 粉末,有 260 的催化剂涂层层的涂的独块巨石吗? | Lina GAN Shan LEI Jian YU Hongtao MA Yo YAMAMOTO Yoshizo SUZUKI Guangwen XU Zhanguo ZHANG | 2015 | Frontiers of Environmental Science & Engineering2015，9，6： | 4 |
| 20 | Coking-resistant Ni-ZrO_2/Al_2O_3 catalyst for CO methanation显示文摘Highly coke-resisting Zr O2-decorated Ni/Al2O3 catalysts for CO methanation were prepared by a two-step process. The support was first loaded with Ni O by impregnating method and then modified with Zr O2 by deposition-precipitation method(IM-DP). Nitrogen adsorptiondesorption, X-ray diffraction, scanning electron microscopy, transmission electron microscopy, thermogravimetric analysis, H2 temperatureprogrammed reduction and desorption, NH3temperature-programmed desorption, and zeta potential analysis were employed to characterize the samples. The results revealed that, compared with the catalysts with the same composition prepared by co-impregnation(CI) and sequential impregnation(SI) methods, the Ni/Al2O3 catalyst prepared by IM-DP showed much enhanced catalytic performance for syngas methanation under the condition of atmospheric pressure and a high weight hourly space velocity of 120000 m L g-1 h-1. In a 80 h life time test under the condition of 300–600°C and 3.0 MPa, this catalyst showed high stability and resistance to coking, and the amount of deposited carbon was only 0.4 wt%. On the contrary, the deposited carbon over the catalyst without Zr O2 reached 1.5 wt% after a 60 h life time test. The improved catalytic performance was attributed to the selective deposition of Zr O2 nanoparticles on the surface of Ni O rather than Al2O3, which could be well controlled via changing the electrostatic interaction in the DP procedure. This unique structure could enhance the dissociation of CO2 and generate surface oxygen intermediates, thus preventing carbon deposition on the Ni particles in syngas methanation. | Qing Liu Fangna Gu Jiajian Gao Huifang Li Guangwen Xu Fabing Su | 2014 | Journal of Energy Chemistry2014，23，6： | 4 |
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