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| 1 | Is leptin related to systemic inflammatory response in acute pancreatitis?显示文摘瞄准:在尖锐胰腺炎评估在 leptin 和全身的发炎之间的关系。方法:有尖锐胰腺炎的连续病人被包括。身体集体索引和浆液样品在承认被获得。Leptin, TNF-alpha, IL-6, -8 和 -10 层次被 ELISA 决定。严厉根据亚特兰大标准被定义。结果:52 (29 女性) 病人们被学习。全面身体团索引在温和、严重的盒子之间是类似的,尽管有严重胰腺炎的女人有更低的身体团索引(P = 0.04 ) 并且男人证明更高的身体质量索引(P = 0.05 ) 。没有差别关于胰腺炎的严厉在 leptin 层次被发现,但是高水平趋于与增加的身体团索引和严重胰腺炎出现在男病人(P = 0.1 ) 。多,变量分析显示出的 A 在 leptin 层次和严厉之间的没有协会。与严厉联系的最强壮的 cytokine 是 IL-6。有另一 cytokines 的 leptin 的关联仅仅为 IL-8 显示出一个趋势(P = 0.058 ) 。结论:高身体团索引仅仅在男性与严厉被联系,它可能与机器人脂肪分发有关。浆液 leptin 似乎不在男性与严重结果在尖锐胰腺炎和它的协会在全身的煽动性的反应上起一个作用可能代表增加的脂肪过多的一个标记。 | Andrés Duarte-Rojo Ana Lezama-Barreda María Teresa Ramírez-Iglesias Mario Peláez-Luna Guillermo Robles-Díaz | 2006 | World Journal of Gastroenterology2006，12，27： | 2 |
| 2 | Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population. | Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud | 2008 | World Journal of Gastroenterology2008，14，42： | 2 |
| 3 | Toll‐Like Receptors and Cytokines are Upregulated during H elicobacter pylori Infection in Children显示文摘 | Hugo Lagunes‐Servin Javier Torres Carmen Maldonado‐Bernal Martha Pérez‐Rodríguez Sara Huerta‐Yépez Armando Madrazo de la Garza Leopoldo Mu?oz‐Pérez Lourdes Flores‐Luna Guillermo Ramón‐García Margarita Camorlinga‐Ponce | 2013 | Helicobacter2013，，6： | 2 |
| 4 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 5 | Disturbed Synthesis of Insulinlike Growth Factor I and Its Binding Proteins May Influence Renal Function Changes in Liver Cirrhosis显示文摘 | Conrado M. Fernández-Rodriguez Ignacio Prada Amalia Andrade Mercedes Moreiras Ramón Guitián Rocío Aller José L. Lledó Guillermo Cacho Jorge Quiroga Jesús Prieto | 2001 | Digestive Diseases and Sciences2001，，6： | 1 |
| 6 | Disturbed Synthesis of Insulinlike Growth Factor I and Its Binding Proteins May Influence Renal Function Changes in Liver Cirrhosis显示文摘 | Conrado M. Fernández-Rodriguez Ignacio Prada Amalia Andrade Mercedes Moreiras Ramón Guitián Rocío Aller José L. Lledó Guillermo Cacho Jorge Quiroga Jesús Prieto | 2001 | Digestive Diseases and Sciences2001，，6： | 1 |
| 7 | TNFRSF11B gene haplotype and its association with bone mineral density variations in postmenopausal Mexican-Mestizo women显示文摘 | David Rojano-Mejía Ramón Mauricio Coral-Vázquez Leticia Cortes Espinosa Sandra Romero-Hidalgo Guillermo López-Medina María del Carmen Aguirre García Agustín Coronel Roberto Ibarra Patricia Canto | 2011 | Maturitas2011，，1： | 1 |
| 8 | A tenant-based resource allocation model for scaling Software-as-a-Service applications over cloud computing infrastructures显示文摘 | Javier Espadas Arturo Molina Guillermo Jiménez Martín Molina Raúl Ramírez David Concha | 2013 | Future Generation Computer Systems2013，，1： | 1 |
| 9 | Exploring QSAR of antiamoebic agents of isolated natural products by MLR,ANN,and RTO显示文摘 | Guillermo Ram'rez-Galicia Heidy Marfnez-Pacheco Ramo'n Gardun-o-Jua'rez | 2011 | Med Chem Res2011，，9： | 1 |
| 10 | Unusual structural effects in a variable-depth box girder bridge: The Pujayo viaduct显示文摘 | óscar Ramón Ramos Frank Schanack Guillermo Ortega Marcos J. Pantaleón | 2010 | Engineering Structures2010，，2： | 1 |
| 11 | Insights into the role of major bioactive dietary nutrients in lamb meat quality:a review显示文摘Feed supplementation withα-linolenic acid(ALA)and linoleic acid(LA)increases their content in muscle,ALA increases n-3 polyunsaturated fatty acids and decrease n-6/n-3 ratio in muscle,and LA increases rumenic acid.However,high LA supplementation may have negative effects on lambs’lipid oxidative stability of meat.When the sources of ALA and LA are fed as fresh forage,the negative effects are counterbalanced by the presence of other bioactive compounds,as vitamin E(mainlyα-tocopherol)and polyphenols,which delay the lipid oxidation in meat.There is a wide consensus on the capability of vitamin E delaying lipid oxidation on lamb meat,and its feed content should be adjusted to the length of supplementation.A high dietary inclusion of proanthocyanidins,phenolic compounds and terpenes reduce the lipid oxidation in muscle and may improve the shelf life of meat,probably as a result of a combined effect with dietary vitamin E.However,the recommended dietary inclusion levels depend on the polyphenol type and concentration and antioxidant capacity of the feedstuffs,which cannot be compared easily because no routine analytical grading methods are yet available.Unless phenolic compounds content in dietary ingredients/supplements for lambs are reported,no specific association with animal physiology responses may be established. | JavierÁlvarez-Rodríguez Olaia Urrutia Sandra Lobón Guillermo Ripoll Juan Ramón Bertolín Margalida Joy | 2022 | Journal of Animal Science and Biotechnology2022，13，4： | 1 |
| 12 | An inter-laboratory study of DNA-based identity,parentage and species testing in animal forensic genetics显示文摘The probative value of animal forensic genetic evidence relies on laboratory accuracy and reliability.Inter-laboratory comparisons allow laboratories to evaluate their performance on specific tests and analyses and to continue to monitor their output.The International Society for Animal Genetics(ISAG)administered animal forensic comparison tests(AFCTs)in 2016 and 2018 to assess the limitations and capabilities of laboratories offering forensic identification,parentage and species determination services.The AFCTs revealed that analyses of low DNA template concentrations(≤300 pg/μL)constitute a significant challenge that has prevented many laboratories from reporting correct identification and parentage results.Moreover,a lack of familiarity with species testing protocols,interpretation guidelines and representative databases prevented over a quarter of the participating laboratories from submitting correct species determination results.Several laboratories showed improvement in their genotyping accuracy over time.However,the use of forensically validated standards,such as a standard forensic short tandem repeat(STR)kit,preferably with an allelic ladder,and stricter guidelines for STR typing,may have prevented some common issues from occurring,such as genotyping inaccuracies,missing data,elevated stutter products and loading errors.The AFCTs underscore the importance of conducting routine forensic comparison tests to allow laboratories to compare results from each other.Laboratories should keep improving their scientific and technical capabilities and continuously evaluate their personnel’s proficiency in critical techniques such as low copy number(LCN)analysis and species testing.Although this is the first time that the ISAG has conducted comparison tests for forensic testing,findings from these AFCTs may serve as the foundation for continuous improvements of the overall quality of animal forensic genetic testing. | Sreetharan Kanthaswamy Torsten Brendel Luis Cancela Denise A.Andrade de Oliveira Bertram Brenig Carmen Cons Julian A.Crespi Markéta Dajbychová Andreas Feldl Tomohito Itoh Vincenzo Landi Amparo Martinez Malgorzata Natonek-Wisniewska Robert F.Oldt Anna Radko Oscar Ramírez Clementina Rodellar Manuel Ruiz-Girón David Schikorski María Elena Turba Guillermo Giovambatista | 2022 | Forensic Sciences Research2022，7，4： | 0 |
| 13 | Design and Implementation of an Extended Collectives Library for Unified Parallel C显示文摘Unified Parallel C(UPC) is a parallel extension of ANSI C based on the Partitioned Global Address Space(PGAS) programming model,which provides a shared memory view that simplifies code development while it can take advantage of the scalability of distributed memory architectures.Therefore,UPC allows programmers to write parallel applications on hybrid shared/distributed memory architectures,such as multi-core clusters,in a more productive way,accessing remote memory by means of different high-level language constructs,such as assignments to shared variables or collective primitives.However,the standard UPC collectives library includes a reduced set of eight basic primitives with quite limited functionality.This work presents the design and implementation of extended UPC collective functions that overcome the limitations of the standard collectives library,allowing,for example,the use of a specific source and destination thread or defining the amount of data transferred by each particular thread.This library fulfills the demands made by the UPC developers community and implements portable algorithms,independent of the specific UPC compiler/runtime being used.The use of a representative set of these extended collectives has been evaluated using two applications and four kernels as case studies.The results obtained confirm the suitability of the new library to provide easier programming without trading off performance,thus achieving high productivity in parallel programming to harness the performance of hybrid shared/distributed memory architectures in high performance computing. | Carlos Teijeiro Guillermo L.Taboada Juan Tourio Ramón Doallo Jos C.Mourio Damivn A.Mallón Brian Wibecan | 2013 | Journal of Computer Science & Technology2013，28，1： | 0 |
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