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| 1 | U-Pb zircon dating of Early Paleozoic gabbro from the Nantinghe ophiolite in the Changning-Menglian suture zone and its geological implication显示文摘The Nantinghe ophiolite is located in the northern part of the Changning-Menglian suture zone in southeast Tibet. It is composed of meta-peridotite, cumulative gabbro, meta-gabbro, plagioclase amphibolite and meta-basalt. Zircon U-Pb dating of the cumulative gabbro gives concordant ages of 473.0±3.8 Ma and 443.6±4.0 Ma respectively, indicating the early and late episodes of mafic magmatisms during the Paleo-Tethys oceanic rifting. The 16 LA-ICPMS zircon U-Pb analyses of meta-gabbro yield a weight mean age of 439±2.4Ma. The gabbro shows relatively low contents of SiO2 (46.46%-52.11%), TiO2 (0.96%-1.14%) and K2O (0.48%-0.75%). Its trace element distribution patterns are partly similar to those of the mid-ocean ridge basalts, and part is depleted in high field strength elements such as Nb, Ta, Zr, Hf and Ti. These features suggest that the mafic rocks were probably formed in a MORB-like or backarc rift basin setting. The zircon U-Pb age of gabbro is consistent with a late crystallization age of the cumulative gabbro from the Nantinghe ophiolite, suggesting that the Paleo-Tethys oceanic basin was opened during 444-439 Ma, possibly as a backarc basin. It is the first precise age which defines the formation time of the early Paleozoic ophiolite in the Changning-Menglian suture zone. These geochronological and geochemical characteristics of the Nantinghe ophiolite are consistent with those from the Guoganjianianshan and Taoxinghu of the Longmu Co-Shuanghu suture in the Qiangtang region. Thus, we suggest that the both Changning-Menglian and Longmu Co-Shuanghu sutures were probably transformed from the relic oceanic crust of the uniform Paleo-Tethys, which likely represents the original and main Paleo-Tethys oceanic basin. | WANG BaoDi WANG LiQuan PAN GuiTang YIN FuGuang WANG DongBing TANG Yuan | 2013 | Chinese Science Bulletin2013，58，8： | 54 |
| 2 | Purifi cation, characterization and hypoglycemic activity of glycoproteins obtained from pea (Pisum sativum L.)显示文摘This study aimed to isolate and characterize the structures of glycoproteins from peas and determine their hypoglycemic activity.The crude pea glycoproteins(PGP)were extracted by hot water and purified by diethylaminoethyl(DEAE)-Sepharose chromatography and Sephadex G-100 size-exclusion chromatography in sequence.Then three main fractions were obtained,namely PGP1,PGP2 and PGP3,with molecular weights of 897615,846740 and 1194692 Da,respectively.The physical and chemical properties of the three fractions were evaluated and compared by Fourier transform infrared spectroscopy(FT-IR),nuclear magnetic resonance(NMR),scanning electron microscope(SEM),high performance liquid chromatography(HPLC)and other analytical techniques.The fraction PGP2 with the highest hypoglycemic activity,was screened using the Caco-2 monolayer cell model.It can inhibit the uptake of glucose in the small intestine,as well as the activities of maltase and sucrase.After simulated gastrointestinal digestion,PGP2 signifi cantly enhanced the inhibitory effect of α-glucosidase,and slightly reduced the inhibitory ability ofα-amylase.In summary,PGP2 possessed strong hypoglycemic activity after digestion.These results indicated that PGP2 has the potential to be developed into a functional food or natural medicine for the treatment of type 2 diabetes mellitus. | Gaoyixin Qin Wu Xu Junping Liu Liyan Zhao Guitang Chen | 2021 | Food Science and Human Wellness2021，10，3： | 8 |
| 3 | Zircon SHRIMP geochronology and Nd-Pb isotopic characteristics of the meta-basalt in the central part of Tibetan Plateau's Qiangtang region显示文摘A small-sized meta-basic rock system is discovered in Qilongwuru Gully of Central Qiangtang’s Shuanghu region and contains a meta-basalt and garnet-bearing plagioclase amphibolite.The zircon U/Pb age of this meta-basalt by SHRIMP analysis is463.3±4.7 Ma,suggesting that this lava formed in the Middle Ordovician,and is consistent with that of the meta-basic rocks in the Taoxing Lake and Guoganjianian Mountain ophiolite found in the Qiangtang plate.As this lava system bears similar geochemistry to N-MORB,it might be a component of ophiolite that represents the trail of the extinction of the Proto-Tethys,suggesting that the formation of Proto-Tethys oceanic basin in the Longmu Co-Shuanghu suture zone could date as far back as to the Middle Ordovician.Isotopic geochemical analysis indicates that the magma source area consists of both depleted mantle(DM)and enriched mantle(EMII)end members and bears Dupal anomaly,similar to that of the Paleo-Tethys in the Neo-Tethys represented by the Yarlung-Tsangpo suture zone,the Paleo-Tethys represented by the Changning-Menglian suture zone,and the Paleo-Tethys in Sanjiang region.This suggests that they have inherited the attribute of the Proto-Tethys mantle domain,and the Longmu Co-Shuanghu suture zone may be a representative of the northern boundary of Gondwana. | PENG ZhiMin GENG QuanRu PAN GuiTang WANG LiQuan ZHANG Zhang CONG Feng GUAN JunLei | 2014 | Science China Earth Sciences2014，57，3： | 5 |
| 4 | Ginger polysaccharide UGP1 suppressed human colon cancer growth via p53,Bax/Bcl-2,caspase-3 pathways and immunomodulation显示文摘In previous study,we got a purified ginger polysaccharide UGP1 and verified its significant antitumor activities on colon cancer HCT116 cells.In this article,we aimed to illustrate the underlying mechanism of UGP1 exerted antitumor activities on colon cancer by using in vitro cell models and in vivo animal models.The results demonstrated that UGP1 could induce S-phase cell cycle arrest,up-regulate the expression of Bax and p53,down-regulate the expression of Bcl-2,and activate the downstream protein caspase-9 and caspase-3,which was related to intrinsic apoptosis pathway on HCT116 cells.Moreover,UGP1 significantly stimulated RAW264.7 cell proliferation and secretion activity.Similarly,UGP1 inhibited tumor proliferation on tumor-bearing mice,increased the expression of p53 and the ratio of Bax/Bcl-2,enhanced the secretion of pro-inflammatory cytokines TNF-α,IL-2,IL-6 and decreased the secretion of pro-tumor cytokines TGF-βand b FGF in serum.In conclusion,it indicated that the UGP 1 could sup press human colon cancer growth by inducing apoptosis via the regulation of p53,caspase-3,and Bax/Bcl-2 ratio-dependent pathway and regulating immune system activity.Thi s investigation provided basic theoretical mechanism of ginger polysaccharideexerted antitumor activities,and contributed to develop a possible functional food or adjuvant agent for prevention or treatment of colon cancer. | Yanfang Qian Chenying Shi Chen Cheng Dengwei Liao Junping Liu Guitang Chen | 2023 | Food Science and Human Wellness2023，12，2： | 4 |
| 5 | Geochemistry and Petrogenesis of Volcanic Rocks in the Yeba Formation on the Gangdise Magmatic Arc, Tibet显示文摘The Early Jurassic bimodal volcanic rocks in the Yeba Formation, situated between Lhasa, Dagzê and Maizhokunggar, composed of metabasalt, basaltic ignimbrite, dacite, silicic tuff and volcanic breccia, are an important volcanic suite for the study of the tectonic evolution of the Gangdise magmatic arc and the Mesozoic Tethys. Based on systematic field investigations, we carried out geochemical studies on representative rock samples. Major and trace element compositions were analyzed for these rock samples by XRF and ICP-MS respectively, and an isotope analysis of Rb-Sr and Sm-Nd was carried out by a MAT 262 mass spectrograph. The results show that the SiO2 contents in lava rocks are 41 %-50.4 % and 64 %-69 %, belonging to calc-alkaline basalt and dacite. One notable feature of the basalt is its low TiO2 content, 0.66 %-1.01 %, much lower than those of continental tholeiite. The ΣREE contents of basalt and dacite are 60.3-135 μg/g and 126.4-167.9 μg/g respectively. Both rocks have similar REE and other trace element characteristics, with enriched LREE and LILE relative to HREE and HFS, similar REE patterns without Eu anomaly. The basalts have depleted Ti, Ta and Nb and slightly negative Nb and Ta anomalies, with Nb*=0.54-1.17 averaging 0.84. The dacites have depleted P and Ti and also slightly negative Nb and Ta anomalies, with Nb*=0.74-1.06 averaging 0.86. Major and trace elemental and isotopic studies suggest that both basalt and dacite originated from the partial melting of the mantle wedge at different degrees above the subduction zone. The spinal lherzolite in the upper mantle is likely to be their source rocks, which might have been affected by the selective metasomatism of fluids with crustal geochemistry. The LILE contents of both rocks were affected by metamorphism at later stages. The Yeba bimodal volcanic rocks formed in a temporal extensional situation in a mature island arc resulting from the Indosinian Gangdise magmatic arc. | Geng Quanru Pan Guitang Jin Zhenmin Wang Liquan Liao Zhongli | 2005 | Journal of China University of Geosciences2005，16，4： | 4 |
| 6 | Research Progress and the Main Achievements of The Regional Geology of China Preface显示文摘Introduction to The Regional Geology of China In 2008, a new project concerning the recompilation of The Regional Geology of China (RGC) was assigned by the Chinese Geological Survey (CGS) and undertaken by the Institute of Geology, Chinese Academy of Geological Sciences (CAGS). Li Tingdong, an academician of the Chinese Academy of Sciences (CAS), is the chief leader and chief scientist of the project. The last time The Regional Geology of China was compiled was in the 1980s (Cheng, 1994). | DING Xiaozhong ZHANG Kexin GAO Linzhi LU Songnian PAN Guitang XIAO Qinghui LIU Yong PANG Jianfeng | 2020 | Acta Geologica Sinica(English Edition)2020，94，4： | 3 |
| 7 | Extraction,purification,characterization and antititumor activity of polysaccharides from Ganoderma lucidum显示文摘 | Liyan Zhao Yanhong Dong Guitang Chen | 2010 | Carbohydrate Polymers2010，80，： | 1 |
| 8 | Extraction, purification, characterization and antimmor activity of polysaccharides from Ganoderma luc/dum显示文摘 | ZHAO Liyan DONG Yanhong CHEN Guitang | 2010 | Carbohydrate Polymers2010，80，3： | 1 |
| 9 | In vitro study on antioxidant activities of peanut protein hydroly- sate显示文摘 | Chen Guitang Zhao Lin Zhao Liyan | 2007 | J Sci Food Agr2007，87，2： | 1 |
| 10 | Tectonic evolution of the Tibet plateau: A working hypothesis based on the archipelago model of omgenesis 显示文摘 | HSU K J PAN GUITANG SENGOR A M C | 1995 | International Geology Review1995，37，： | 1 |
| 11 | Modulation of o- vine SBD-1 expression by 17 beta-estradiol in ovine oviduct epithelial cells 显示文摘 | Wen Shiyong Cao Guitang Bao Tuya | 2012 | BMC Veterinary Research2012，8，： | 1 |
| 12 | Effect of nanocomposite-based packaging on preservation quality of green tea during one-year ambient storage显示文摘 | ZHAO Liyan LI Fang CHEN Guitang | 2012 | International Journal of Food Science and Technology2012，47，3： | 1 |
| 13 | Extraction, purification, characterization and antitumor activity of polysaccharides from Ganoderma lucidurn显示文摘 | ZHAO Liyan DONG Yanhong CHEN Guitang | 2010 | Carbohydrate Polymers2010，80，3： | 1 |
| 14 | Extraction, purification, characterization and antitumor activity of polysaccharides from Ganoderma lucidum显示文摘 | Zhao Liyan Dong Yanhong Chen Guitang | 2010 | Carbohydrate Polymers2010，80，： | 1 |
| 15 | Extraction, purification, characterization and antitumor activity of polysaccharides from Ganoderma lucidum显示文摘 | Liyan Zhao Yanhong Dong Guitang Chen Qiuhui Hu | 2009 | Carbohydrate Polymers2009，，3： | 1 |
| 16 | Tectonic evolution of the Qinghai-Tibet Plateau显示文摘 | Pan Guitang Wang Liquan Li Rongshe | 2012 | Journal of Asian Earth Sciences2012，53，： | 1 |
| 17 | Tectonic evolutionof the Tibetan Plateau : A working hypothesis based on theArchipelago model of orogenesis 显示文摘 | HSU K J PAN GUITANG SENGOR A M C | 1995 | International GeologyReview1995，37，： | 1 |
| 18 | Extraction, purification ,characterization and antitumor activity of polysaccharides from Ganoderma lucidum 显示文摘 | Liyan Zhao Yanhong Dong Guitang Chen and Qiuhui Hu | 2010 | Carbohydrate Polymers2010，80，： | 1 |
| 19 | Sanjiang Tethyan metallogenesis in S.W. China: Tectonic setting, metallogenic epochs and deposit types显示文摘 | Zengqian Hou Khin Zaw Guitang Pan Xuanxue Mo Qiang Xu Yunzhong Hu Xingzhen Li | 2007 | Ore Geology Reviews2007，，1： | 1 |
| 20 | MULTI-ARC BASIN SYSTEM OF THE KUNLUN OROGENIC BELT AND PAN-CATHYSIAN CONTINENTAL ACCRETION显示文摘After Rodinia supercontinent was disintegrated in Late Proterozoic, an ocean, namely, Tethys Ocean, occurred between Gondwana continental group and Pan-Cathaysian continental group from Late Proterozoic to Mesozoic. From Early Paleozoic to Mesozoic, Tethys Ocean was subducted toward Pan-Cathaysian block group, which results in backarc expansion, arc-land collision and forearc accretion. When the backarc basin expands and reaches the small oceanic basin, ophiolite melange will be generated. As accretion had already occurred in the south of the continental margin in the earlier stage, the succeeding backarc expansion and the frontal arc position were migrated toward south correspondingly. Therefore, multiple ophiolite belts and magmatic rock belts occurred, and show a trend of decreasing age from north toward south. As the continental margin was split and migrated toward south and reached a high latitude position, i.e., with the shortening and subduction of oceanic crust, the sedimentary bodies at high latitude was accreted continuously toward low latitude area together with the formation of oceanic island, mixing of cold-type and warm-type organism was generated. Moreover,blocks split and separated from Pan-Cathaysian or Gondwana continental group cannot traverse the oceanic median ridge and joins with another continental block. As a result, the Kunlun belt on the SW margin of the Pan-Cathaysian land was resulted from the multi-arc orogenesis such as the backarc seabed expansion, arc-arc collision, arc-land collision oceanic bed, and the continuous southward accretion process. | YIN Fuguang, PAN Guitang and LI Xingzhen(Chengdu Institute of Geology and Mineral Resources, Chengdu, SC610081, China) | 2003 | Geotectonica et Metallogenia2003，27，1： | 1 |
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