|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Factors Associated with Thrombolysis Outcome in Ischemic Stroke Patients with Atrial Fibrillation显示文摘The outcome of early intravenous thrombolysis for ischemic stroke in patients with atrial fibrillation(AF)is worse than that without thrombosis. How to increase the efficacy of intravenous thrombolysis for AF-related ischemic stroke remains largely unknown. In this study, we investigated factors that influence the effect of intravenous thrombolysis in these patients. Our results showed that thrombolysis was independently associated with a favorable outcome(P \ 0.001) and did not influence the mortality of AF-related ischemic stroke, although it increased the risk of hemorrhage within 24 h after treatment. Risk factors for a poor outcome at admission were:heart failure(P = 0.045); high systolic pressure(P = 0.039); high blood glucose(P = 0.030); and a high National Institutes of Health Stroke Scale(NIHSS) score(P \ 0.001). Moreover, high systolic pressure at admission(P = 0.007), high blood glucose(P = 0.027), and a high NIHSS score(P \ 0.001) were independent risk factors for mortality at 3 months. Besides thrombolysis, a high NIHSS score(P = 0.006) and warfarin taken within 48 h before stroke onset(P = 0.032) were also independent risk factors for symptomatic hemorrhage within 24 h after treatment. Ischemic stroke patients with AF benefited from intravenous thrombolysis with recombinant tissue plasminogen activator within 4.5 h after stroke. | Qiuyun Zhao Xiaobo Li Wanli Dong Min Ye Yongjun Cao Meijuan Zhang Qiantao Cheng Junshan Zhou Guofang Chen Ming Yu Shanshan Hong Xiue Wei Bei Wang Guiyun Cui Peng Zhang Hong Ding Rongzhen Xu Yan Chen Yun Xu | 2016 | Neuroscience Bulletin2016，32，2： | 13 |
| 2 | Online single particle measurement of fireworks pollution during Chinese New Year in Nanning显示文摘Time-resolved single-particle measurements were conducted during Chinese New Year in Nanning, China. Firework displays resulted in a burst of SO_2, coarse mode, and accumulation mode(100–500 nm) particles. Through single particle mass spectrometry analysis, five different types of particles(fireworks-metal, ash, dust, organic carbon-sulfate(OC-sulfate), biomass burning) with different size distributions were identified as primary emissions from firework displays. The fireworks-related particles accounted for more than70% of the total analyzed particles during severe firework detonations. The formation of secondary particulate sulfate and nitrate during firework events was investigated on single particle level. An increase of sulfite peak(80SO_3^-) followed by an increase of sulfate peaks(97HSO_4^-+ 96SO_4^-) in the mass spectra during firework displays indicated the aqueous uptake and oxidation of SO_2 on particles. High concentration of gaseous SO_2, high relative humidity and high particle loading likely promoted SO_2 oxidation. Secondary nitrate formed through gas-phase oxidation of NO_2 to nitric acid, followed by the condensation into particles as ammonium nitrate. This study shows that under worm, humid conditions, both primary and secondary aerosols contribute to the particulate air pollution during firework displays. | Jingyan Li Tingting Xu Xiaohui Lu Hong Chen Sergey A.Nizkorodov Jianmin Chen Xin Yang Zhaoyu Mo Zhiming Chen Huilin Liu Jingying Mao Guiyun Liang | 2017 | Journal of Environmental Sciences2017，29，3： | 3 |
| 3 | The cost of obsessive- compulsive disorder (OCD) in China: a multi- center cross- sectional survey based on hospitals显示文摘Background Obsessive-compulsive disorder(OCD)is considered a very debilitating disorder with severe loss of quality of life and income.Aims This study estimates the quality of life and economic consequences of OCD in China.Methods The research team interviewed 639 patients with OCD in 13 hospitals in 12 cities in China.The direct method was used to get the direct cost of OCD.Indirect costs associated with OCD were estimated using the human capital approach.Linear regression analysis was conducted for quality of life and generalised linear model analysis was conducted for total cost.Sensitivity analysis was used to analyse the uncertainty of total cost.Results The mean quality of life score for OCD was 52.78(20.46).The annual total cost of OCD per capita was 24503.78(95%CI:22621.53 to 26386.03)renminbi(RMB)(US$3465.88(95%CI:US$3199.65 to US$3732.11)).The annual cost of OCD in China was estimated to be 37.74 billion(95%CI:34.95 billion to 40.53 billion)RMB(equal to US$5.34 billion(95%CI:US$4.94 billion to US$5.73 billion)).Sensitivity analysis showed that the total annual cost of OCD in China was between 23.15 billion RMB(US$3.27 billion)and 370.00 billion RMB(US$52.33 billion).Worse social function status,more psychiatric symptoms and higher Yale Brown Obsessive-Compulsive Scale(Y-BOCS)score were associated with worse quality of life.The numbers of clinic visits and hospitalisations,socioeconomic status,education,Y-BOCS scores and age were found to be significantly associated with total cost.Conclusions OCD is associated with low quality of life and high costs in China.The findings call for concerted efforts to improve services for patients with OCD.Improvements may include early detection and diagnosis,the provision of evidence-based treatments and relapse prevention strategies. | Weili Yang Zhen Tang Xijin Wang Xiancang Ma Yuqi Cheng Bin Wang Ping Sun Wenxin Tang Jia Luo Changhong Wang Ping Li Guiyun Xu Jun Yan Vlasios Brakoulias Zhen Wang | 2021 | General Psychiatry2021，34，6： | 3 |
| 4 | The influences of SE infection on layers' production performance,egg quality and blood biochemical indicators显示文摘Background:Salmonella enterica serovar Enteritidis(SE),as a major cause of foodbom illness,infects humans mainly through the egg.However,the symptom of laying hens usually is not typical and hard to diagnosis.In the present study,it is studied that the influences of SE infection on layers’ performance,egg quality and blood biochemical indicators.It will help us to improve the strategy to control SE infection in commercial layers.One hundred layers at 20 wk of age were divided into 2 groups,60 hens for experiment and others for control.The experiment group was fed with the dosage of 10~8 CFU SE per hen.The specific PCR was used to detect the deposition of SE.On the 8 d after SE infection,10 hens from the control group and 30 hens from the experimenta group were slaughtered to detect the SE colonization.The production performance,egg quality and blood biochemical indices were also analyzed.Results:The results showed that the colonization rate of SE was highest in caecum contents(55.17%) and lowest in vagina(17.24%).For the eggs the detection rate of SE was highest on the eggshell(80.00%) and lowest in yolk(18.81%).SE infection had no significant influence on production performance and egg qualities(P > 0.05).The difference of laying rate between the experimental and control groups was less than 0.30%,and both were approximately equal to 82.00%.The blood analysis showed that the aspartic aminotransferase(AST) and alanine aminotransferase(ALT) of experimental group was significantly higher than those of control group(P < 0.05).For experimental and control groups AST values were 236.22 U/l and 211.84 U/l respectively,and ALT values were32.19 U/l and 24.55 U/l.All of coefficients were less than 20%.The colonization of SE in organs increases the enzyme activities of AST and ALT in blood.Conclusions:SE in feed could invade the oviduct and infect the forming eggs.It significantly increased the concentration of ALT and AST in blood.However,SE infection was hard to be observed from the appearances of layer and egg.It might be a dangerous risk to human health. | Shijie Fan Jiangxia Zheng Zhongyi Duan Ning Yang Guiyun Xu | 2014 | Journal of Animal Science and Biotechnology2014，5，3： | 2 |
| 5 | Recognizing Finite Groups Through Order and Degree Patterns显示文摘The degree pattern of a finite group G associated with its prime graph has been introduced by Moghaddamfar in 2005 and it is proved that the following simple groups are uniquely determined by their order and degree patterns:All sporadic simple groups,the alternating groups Ap(p≥5 is a twin prime)and some simple groups of the Lie type.In this paper,the authors continue this investigation.In particular,the authors show that the symmetric groups Sp+3,where p+2 is a composite number and p+4 is a prime and 97 | Yanxiong YAN Guiyun CHEN Liangcai ZHANG Haijing XU | 2013 | Chinese Annals of Mathematics,Series B2013，34，5： | 2 |
| 6 | Effect of cerium on microstructure,mechanical properties and corrosion properties of Al-Zn-Mg alloy显示文摘The effects of trace Ce on the microstructure,mechanical properties and corrosion resistance of Al-Zn-Mg alloy were studied by means of metallographic analysis,scanning electron microscopy(SEM),mechanical tensile test,slow strain rate tensile test,cyclic polarization curve test,electrochemical impedance spectroscopy test and anodic oxidation test.The results show that the addition of trace Ce has little effect on the strength of Al-Zn-Mg alloy,but can significantly improve the corrosion resistance of the alloy;The mechanical properties and corrosion resistance of the alloys decrease significantly with the addition of excessive Ce;the addition of 0.04 wt%Ce can reduce significantly the self-corrosive current density of AlZn-Mg alloy and increase obviously passivation film resistance of the alloy.The stress corrosion sensitivity index decreases from 0.612 to 0.219,which improves the corrosion resistance properties significantly. | Guiyun Hu Changjun Zhu Daofen Xu Pengxuan Dong Kanghua Chen | 2021 | Journal of Rare Earths2021，39，2： | 2 |
| 7 | Transcriptome responses to heat stress in hypothalamus of a meat-type chicken显示文摘Background:Heat stress has resulted in great losses in poultry production.To address this issue,we systematically analyzed chicken hypothalamus transcriptome responses to thermal stress using a 44 k chicken Agilent microarray,Methods:Hypothalamus samples were collected from a control group reared at 25℃,a heat-stress group treated at 34℃ for 24 h,and a temperature-recovery group reared at 25℃ for 24 h following a heat-stress treatment.We compared the expression profiles between each pair of the three groups using microarray data.Results:A total of 1,967 probe sets were found to be differentially expressed in the three comparisons with P < 0.05 and a fold change(FC) higher than 1.5,and the genes were mainly involved in self-regulation and compensation required to maintain homeostasis.Consistent expression results were found for 11 selected genes by quantitative real-time PCR.Thirty-eight interesting differential expression genes were found from GO term annotation and those genes were related to meat quality,growth,and crucial enzymes.Using these genes for genetic network analysis,we obtained three genetic networks.Moreover,the transcripts of heat-shock protein,including Hsp 40 and Hsp 90,were significantly altered in response to thermal stress.Conclusions:This study provides a broader understanding of molecular mechanisms underlying stress response in chickens and discovery of novel genes that are regulated in a specific thermal-stress manner. | Hongyan Sun Runshen Jiang Shengyou Xu Zebin Zhang Guiyun Xu Jiangxia Zheng Lujiang Qu | 2015 | Journal of Animal Science and Biotechnology2015，6，3： | 2 |
| 8 | Genetic analysis and gene cloning of a triangular hull 1 (tri1) mutant in rice (Oryza sativa L.)显示文摘Grain shape and size are two key factors that determine rice yield and quality. In the present study, a rice triangular hull mutant (tri1) was obtained from the progeny of japonica rice variety Taipei 309 treated with 60Co γ-rays. Compared to the wild type, the tri1 mutant presents a triangular hull, and exhibits an increase in grain thickness and protein content, but with a slight decrease in plant height and grain weight. Genetic analysis indicated that the mutant phenotype was controlled by a recessive nuclear gene which is stably inherited. Using a map-based cloning strategy, we fine-mapped tri1 to a 47-kb region between the molecular markers CHR0122 and CHR0127 on the long arm of chromosome 1, and showed that it co-segregates with the molecular marker CHR0119. According to the rice genome sequence annotation there are six predicated genes within the mapped region. Sequencing analysis of the mutant and the wild type indicated that there was a deletion of an A nucleotide in exon 3 of the OsMADS32 gene, which could result in a downstream frameshift mutation and premature termination of the predicted polypeptide. Both semi-quantitative and real-time RT-PCR analyses showed that this gene expressed highly in young inflorescences, while expressed at very low levels in other tissues. These results implied that the OsMADS32 gene could be a candidate of TRI1. Taken together, the results of this study lay the foundation for further investigation into the molecular mechanisms regulating rice caryopsis development. | FENG GongNeng ZHANG ChangQuan TANG MingYong ZHANG GuiYun XU ChenWu GU MingHong LIU QiaoQuan | 2013 | Chinese Science Bulletin2013，58，24： | 2 |
| 9 | Visible-light-induced regioselective cross-dehydrogenative coupling of 2-isothiocyanatonaphthalenes with amines using molecular oxygen显示文摘An efficient and eco-friendly protocol for the construction of naphtho[2,1-d]thiazol-2-amines through visible-light photoredox-catalyzed C(sp2)–H/S–H cross-dehydrogenative coupling reactions between 2-isothiocyanatonaphthalenes and amines was established.In this reaction,the new C–N and C–S bonds are formed simultaneously in a single step.This new method provides a straightforward approach for constructing valuable sulfur-containing compounds. | Ziyu Gan Guoqing Li Xiaobo Yang Qiuli Yan Guiyun Xu Gaoyang Li Yuan-Ye Jiang Daoshan Yang | 2020 | Science China Chemistry2020，63，11： | 2 |
| 10 | Origin and domestication history of Peking ducks deltermined through microsatellite and mitochondrial marker analysis显示文摘In order to elucidate the domestication history of Peking ducks, 190 blood samples from six Chinese indigenous duck breeds were collected with186 individualsgenotyped by 15 microsatellite markers. Both the FST and Nei’s standard genetic distances (Ds) from the microsatellite data indicated high genetic differentiation between Peking duck and other Chinese indigenous breeds. The haplotype network with mtDNA data showed that most of the Peking duck haplotypes were distinctly different from those of other domestic breeds. Although the H01 haplotype was shared by all domesticated duck breeds, Peking ducks displayed 12 specific domestic duck haplotypes, including four similar haplotypes H02, H04, H08 and H22, that formed a single haplogroup (A). Both H02 and H22 haplotypes were also shared by mallard and Peking ducks, indicating that Peking ducks originated from wild mallard ducks. | QU LuJiang, LIU Wei, YANG FangXi, HOU ZhuoCheng, ZHENG JiangXia, XU GuiYun & YANG Ning State Laboratory for Agrobiotechnology and Department of Animal Science and Technology, China Agricultural University, Beijing 100193, China | 2009 | Science China(Life Sciences)2009，52，11： | 2 |
| 11 | Deviation analysis and optimization of offset slider-crank mechanism based on the simulation 显示文摘 | Sun Jian Xu Guiyun | 2013 | Information Technology Journal2013，12，12： | 1 |
| 12 | Increased a- tocotrienol content in seeds of transgenic rice overex- pressing Arabidopsis 3' - tocopherol methyltransferase 显示文摘 | ZHANG Guiyun LIU Rum XU Geng | 2013 | Transgenic Res2013，22，1： | 1 |
| 13 | Scientific objectives of the Hot Universe Baryon Surveyor(HUBS) mission显示文摘The Hot Universe Baryon Surveyor(HUBS) is a proposed space-based X-ray telescope for detecting X-ray emissions from the hot gas content in our universe. With its unprecedented spatially-resolved high-resolution spectroscopy and large field of view,the HUBS mission will be uniquely qualified to measure the physical and chemical properties of the hot gas in the interstellar medium, the circumgalactic medium, the intergalactic medium, and the intracluster medium. These measurements will be valuable for two key scientific goals of HUBS, namely to unravel the AGN and stellar feedback physics that governs the formation and evolution of galaxies, and to probe the baryon budget and multi-phase states from galactic to cosmological scales. In addition to these two goals, the HUBS mission will also help us solve some problems in the fields of galaxy clusters, AGNs, difuse X-ray backgrounds, supernova remnants, and compact objects. This paper discusses the perspective of advancing these fields using the HUBS telescope. | Joel Bregman Renyue Cen Yang Chen Wei Cui Taotao Fang Fulai Guo Edmund Hodges-Kluck Rui Huang Luis C.Ho Li Ji Suoqing Ji Xi Kang Xiaoyu Lai Hui Li Jiangtao Li Miao Li Xiangdong Li Yuan Li Zhaosheng Li Guiyun Liang Helei Liu Wenhao Liu Fangjun Lu Junjie Mao Gabriele Ponti Zhijie Qu Chenxi Shan Lijing Shao Fangzheng Shi Xinwen Shu Lei Sun Mouyuan Sun Hao Tong Junfeng Wang Junxian Wang Q.Daniel Wang Song Wang Tinggui Wang Weiyang Wang Zhongxiang Wang Dandan Xu Haiguang Xu Heng Xu Renxin Xu Xiaojie Xu Yongquan Xue Hang Yang Feng Yuan Shuinai Zhang Yuning Zhang Zhongli Zhang Yuanyuan Zhao Enping Zhou Ping Zhou | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，9： | 1 |
| 14 | Genetic basis of negative heterosis for growth traits in chickens revealed by genome-wide gene expression pattern analysis显示文摘Background:Heterosis is an important biological phenomenon that has been extensively utilized in agricultural breeding.However,negative heterosis is also pervasively observed in nature,which can cause unfavorable impacts on production performance.Compared with systematic studies of positive heterosis,the phenomenon of negative heterosis has been largely ignored in genetic studies and breeding programs,and the genetic mechanism of this phenomenon has not been thoroughly elucidated to date.Here,we used chickens,the most common agricultural animals worldwide,to determine the genetic and molecular mechanisms of negative heterosis.Results:We performed reciprocal crossing experiments with two distinct chicken lines and found that the body weight presented widely negative heterosis in the early growth of chickens.Negative heterosis of carcass traits was more common than positive heterosis,especially breast muscle mass,which was over−40%in reciprocal progenies.Genome-wide gene expression pattern analyses of breast muscle tissues revealed that nonadditivity,including dominance and overdominace,was the major gene inheritance pattern.Nonadditive genes,including a substantial number of genes encoding ATPase and NADH dehydrogenase,accounted for more than 68%of differentially expressed genes in reciprocal crosses(4257 of 5587 and 3617 of 5243,respectively).Moreover,nonadditive genes were significantly associated with the biological process of oxidative phosphorylation,which is the major metabolic pathway for energy release and animal growth and development.The detection of ATP content and ATPase activity for purebred and crossbred progenies further confirmed that chickens with lower muscle yield had lower ATP concentrations but higher hydrolysis activity,which supported the important role of oxidative phosphorylation in negative heterosis for growth traits in chickens.Conclusions:These findings revealed that nonadditive genes and their related oxidative phosphorylation were the major genetic and molecular factors in the negative heterosis of growth in chickens,which would be beneficial to future breeding strategies. | Chunning Mai Chaoliang Wen Zhiyuan Xu Guiyun Xu Sirui Chen Jiangxia Zheng Congjiao Sun Ning Yang | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 1 |
| 15 | Thin - layer chromatography of phospholipids and their lyso forms : application to determination of extracts from rat hippocampal CA1 re-gion显示文摘 | XU Guiyun WAKI H KON K | 1996 | Microchemical Journal1996，53，： | 1 |
| 16 | Correlation analysis of the total IgY level in hen serum, egg yolk and offspring serum显示文摘The correlation between IgY levels of the serum and the yolk has been well documented in wild and domestic birds. The levels of total yolk IgY can be an index of the general health status of birds and may contribute to breeding programs when fitness of the offspring is a concern. We measured the levels of total serum IgY and yolk IgY in three different breeds(White Leghorn, Silkie and Dongxiang blue-shell) using indirect ELISA, and found that there was a significantly positive correlation between the levels of total serum IgY and total yolk IgY in all three breeds(White Leghorn: r=0.404, P<0.001, n=100; Silkie: r=0.561, P<0.001, n=70; Dongxiang blue-shell: r=0.619, P<0.001, n=30). We also measured the total serum IgY levels in the 3-day-old offspring hatched from the Silkie hens and results were significantly correlated for serum IgY levels(r=0.535, P<0.001, n=70) and the yolk IgY levels(r=0.481, P<0.001, n=70). The regression analysis showed simple linear regression between IgY levels in hen serum, yolk and offspring serum. Our results suggest that total IgY level could be used as an index for chicken fitness. | Hancong Sun Sirui Chen Xia Cai Guiyun Xu Lujiang Qu | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 1 |
| 17 | Novel sensor scheduling and energy-efficient quantization for tracking target in wireless sensor networks显示文摘This paper focuses on sensor scheduling and information quantization issues for target tracking in wireless sensor networks (WSNs). To reduce the energy consumption of WSNs, it is essential and effective to select the next tasking sensor and quantize the WSNs data. In existing works, sensor scheduling' goals include maximizing tracking accuracy and minimizing energy cost. In this paper, the integration of sensor scheduling and quantization technology is used to balance the tradeoff between tracking accuracy and energy consumption. The main characteristic of the proposed schemes includes a novel filtering process of scheduling scheme, and a compressed quantized algorithm for extended Kalman filter (EKF). To make the algorithms more efficient, the proposed platform employs a method of decreasing the threshold of sampling intervals to reduce the execution time of all operations. A real tracking system platform for testing the novel sensor scheduling and the quantization scheme is developed. Energy consumption and tracking accuracy of the platform under different schemes are compared finally. | Guiyun LIU Bugong XU | 2013 | 控制理论与应用(英文版)2013，11，1： | 1 |
| 18 | The ptimism of Flow esistant pproximate ormula of erschelBulkley luid 显示文摘 | XU Guiyun LIN Xuedong ZHANG Yongzhong | 2004 | Journal of China University of Mining and Technology2004，16，2： | 1 |
| 19 | Fabrication of nanocomposite electrochemical sensors with poly(3,4-ethylenedioxythiophene)conductive polymer and Au nanoparticles adsorbed on carboxylated nanocrystalline cellulose显示文摘Au nanoparticles(AuNPs)were prepared by reducing HAuCl4 with NaBH4,and then adsorbed uniformly on the surface of carboxylated nanocrystalline cellulose(CNCC).The obtained AuNPs/CNCC particles were doped into a conductive polymer of poly(3,4-ethylenedioxythiophene)(PEDOT)to yield a highly conductive nanocomposite,which was deposited onto a glassy carbon electrode(GCE)by an electrochemical method.The PEDOT/AuNPs/CNCC nanocomposite showed low electrochemical impedance and good electrocatalytic activity toward ascorbic acid.Based on this novel nanocomposite material,an amperometric sensor was developed for the detection of ascorbic acid with a detection limit as low as 0.29μM.When operated at-0.15 V,the sensor detected ascorbic acid in the range of 0.88μM to 15000μM. | Jinshi Fan Shaoping Liang Mingming Zhang Guiyun Xu | 2018 | Journal of Bioresources and Bioproducts2018，3，1： | 0 |
| 20 | Recognizing the Automorphism Groups of Mathieu Groups Through Their Orders and Large Degrees of Their Irreducible Characters*显示文摘It is a well-known fact that characters of a finite group can give important information about the structure of the group. It was also proved by the third author that a finite simple group can be uniquely determined by its character table. Here the authors attempt to investigate how to characterize a finite almost-simple group by using less information of its character table, and successfully characterize the automorphism groups of Mathieu groups by their orders and at most two irreducible character degrees of their character tables. | Yanxiong YAN Liangcai ZHANG Haijing XU Guiyun CHEN | 2016 | Chinese Annals of Mathematics,Series B2016，37，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员