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| 1 | Expression of nuclear factor-KB in hepatocellular carcinoma and its relation with the X protein of hepatitis B virus显示文摘AIM In this study we investigated therelationship of the X protein of HBV and nuclearfactor-KB (NF-κB) and the expression of NF-KB inhuman hepatocellular carcinoma tissues.METHODS Immunohistochemistry SP methodwas used to detect the expression of NF-κB and the X protein of HBV in human hepatocellularcarcinoma tissues of 52 cases. Gene transfectionmediated by lipofectamine was used to transfectthe eukaryotic expression vector pCDNA3. 1-HBXof HBV x gene into human hepatocellularcarcinoma cell line HCC-9204 and NF-κB wasdetected.RESULTS NF-κB was widely expressed inhuman hepatocellular carcinoma tissues in atotal of 52 cases and its expression was relatedto the X protein of HBV. NF-KB was localizedboth in the cytoplasm and . The nuclei ofhepatocellular carcinoma cells in 11 cases whichwere positive for the X protein of HBV while in 41cases negative for the X protein of HBV, NF-Kbwas only localized in the cytoplasm ofhepatocellular carcinoma cells but translocatedto the nuclei of hepatocellular carcinoma cellsafter the eukaryotic expression vectorpCDNA3.1-HBX was transfected into HCC-9204cells.CONCLUSION This study strongly suggeststhat the nuclear factor NF-KB is widely expressedin hepatocellular carcinoma tissues in differentstyles according to the expression of the Xprotein of HBV. NF-κB is abnormally activated inhepatocellular carcinoma, which is probablyrelated to the X protein of HBV. The X protein ofHBV can activate NF-κB to translocate into nucleiof hepatocellular carcinoma cells. | Shuang Ping Guo~1 Wen Liang Wang~1 Yu Qiang Zhai~2 Yi Ling Zhao~1 ~1Department of Pathology,Xijing Hospital of the Fourth Military Medical University,Xi’an,China ~2Department of Urology,the Central Hospital of Xi’an,China | 2001 | World Journal of Gastroenterology2001，7，3： | 55 |
| 2 | Chinese Economic Structure and SDA Model | CHEN Xi\|kang 1,\ GUO Ju\|e 2 1. Academy of Machemation and Systems Science, Chinese Academy of Science Beijing 100080, China 2. Shaanxi Institute of Finance and Economics, Xi′an 710061, China | 2000 | Systems Science and Systems Engineering2000，10，2： | 40 |
| 3 | Grain-size features of a Miocene loess-soil sequence at Qinan: Implications on its origin显示文摘In this study, grain-size of 507 bulk samples from the QA-I Miocene loess-soil sequence at Qinan were analyzed, and the grain-size features are compared with those of typical Quaternary loess and soil samples, representative lacustrine and fluvial samples. The results indicate that the grain-size distribution pattern of the Miocene loess is essentially similar to that of Quaternary loess, but greatly differs from the lacustrine and fluvial sediments. Loess layers are regularly coarser than soil layers, indicating cyclical climate changes. Median grain-size along the 253.1 m sequence varies from 6 to 13 μm and the >63 μm fraction represents only 5.3% in maximum, 0.9% in average. Long-term grain-size variations are consistent with the loess accumulation rate at Qinan and with the eolian mass accumulation rate in the North Pacific. These features firmly indicate an eolian origin of the studied sequence, and also reveal a coeval changes between the long-term changes of eolian grain-size and continental aridity in the dust source regions. | QIAO Yansong1,3, GUO Zhengtang2,1, HAO Qingzhen1, YIN Qiuzhen1, YUAN Baoyin1 & LIU Tungsheng1 1. Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China 2. Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710075, China 3. Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081, China | 2006 | Science China Earth Sciences2006，49，7： | 33 |
| 4 | Diversity and ecological distribution of endophytic fungi associated with medicinal plants显示文摘A total of 973 isolates of endophytic fungi were recovered from 1144 tissue fragments of the six me-dicinal plant species belonging to 4 families collected in the Beijing Botanical Garden. Of these isolates 778 sporulated and were identified into 21 taxa by morphological characteristics. Among the taxa 11 belonged to Coelomycetes, 6 to Ascomycetes, and 4 to Hyphomycetes. Various numbers of endophytic fungi (5―8 taxa) were obtained from each plant. Alternaria alternata was the dominant species in the 6 plants, and Microsphaeropsis conielloides was also dominant in Eucommia ulmoides. There were high colonization rates (47.9%―63.1%) and isolation rates (0.7―0.93) of endophytic fungi, and they were conspicuously higher in twigs than those in leaves in the 6 plants examined. The colonization and isolation rates of endophytic fungi increased with the twig age. The results based on the analyses of cluster and Sorenson's similarity coefficients indicated that some endophytic fungi showed a certain degree of host and tissue preference. | SUN JianQiu1,2,3, GUO LiangDong1, ZANG Wei2,3, PING WenXiang4 & CHI DeFu3 1 Systematic Mycology and Lichenology Laboratory, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China 2 College of Life Science and Engineering, Qiqihar University, Qiqihar 161006, China 3 College of Forestry, Northeast Forestry University, Harbin 150040, China 4 College of Life Science, Heilongjiang University, Harbin 150080, China | 2008 | Science China(Life Sciences)2008，51，8： | 34 |
| 5 | Deficit of mitochondria-derived ATP during oxidative stress impairs mouse MII oocyte spindles显示文摘尽管在母亲的老化和不孕的氧化应力的角色被建议了,内在的机制充分没被理解。现在的学习被设计在氧化应力下面在中期 II (MII ) 卵母细胞决定在 mitochondrial 功能和锭子稳定性之间的关系。MII 老鼠卵母细胞当面与 H2O2 被对待或渗透转变毛孔(PTP ) 的缺席块 ers cyclosporin A (CsA ) 。另外,抗氧化剂 N-acetylcysteine (NAC ) , F0/F1 synthase 禁止者 oligomycin A,线粒体 uncoupler 羰基氰化物 4-trifluoro-methoxyphenylhydrazone (FCCP ) 或加 2.5 公里 Ca2+(Th+2.5 公里 Ca2+) 的 thapsigargin 在机械学的研究被使用。卵母细胞锭子和染色体的词法分析被执行并且 mitochondrial 膜潜力(DeltaPsim ) ,细胞质的免费的钙集中([Ca2+] c ) 并且在卵母细胞以内的细胞质的 ATP 内容也是 assayed。在一时间 -- 并且 H2O2 剂量依赖者举止,锭子在卵母细胞以后被发现的 meiotic 的混乱与 H2O2 被对待,它被预告的处理与 NAC 阻止。H2O2 的管理导致了 DeltaPsim 的驱散,的增加[Ca2+] 在细胞质的 ATP 的 c 和减少铺平。到 H2O2 处理的卵母细胞的这些有害回答能被孵化前与 CsA 堵住。类似于驱散的 H2O2,两 oligomycin A 和 FCCP DeltaPsim,减少的细胞质的 ATP 内容和拆卸的 MII 卵母细胞锭子,当时高[Ca2+] c 独自没在锭子形态学上有效果。在结论,在导出线粒体的 ATP 的减少可以在氧化应力期间引起老鼠 MII 卵母细胞锭子的拆卸,大概由于 mitochondrial PTP 的开始。 | Xiao Zhang~(1,2,*) Xue Qing Wu~(1,3,*) Shuang Lu~(4,5,6) Ying Lu Guo~1 Xu Ma~(4,5,6) ~1Peking University First Hospital,Institute of Urology of Peking University,Beijing 100034,China ~2Reproductive and Genetic Center of Peking University First Hospital,Beijing 100034,China ~3Department of Obstetrics and Gynecology,Shanxi Medical University Second Hospital,Taiyuan 030000,China ~4Reproductive and Genetic Center of National Research Institute for Family Planning,Beijing 100038,China ~5Department of Genetics, Peking Union Medical College, Beijing 100038. China ~6 WHO Collaborative Center for Research in Human Reproduction,Beijing 100038,China | 2006 | Cell Research2006，16，10： | 24 |
| 6 | Antihepatoma effect of alpha-fetoprotein antisense phosphorothioate oligodeoxyribonucleotides in vitro and in mice显示文摘AIM To evaluate antihepatoma effect ofantisense phosphorothioate oligodeo-xyribonucleotides (S-ODNs) targeted to alpha-fetoprotein (AFP) genes in vitro and in nudemice.METHODS AFP gene expression was examinedby immunocytochemical method or enzyme-linked immunosorbent assay. Effect of S-ODNson SMMC-7721 human hepatoma cell growth invitro was determined using microculturetetrazolium assay. In vivo antitumor activitiesof S-ODNs were monitored by measuring tumorweight differences in treated and control micebearing SMMC-7721 xenografts. Induction of cellapoptosis was evaluated by fluorescence-activated cell sorter (FACS) analysis.RESULTS Antisense S-ODN treatment led toreduced AFP gene expression. Specificantisense S-ODNs, but not control S-ODNs,inhibited the growth of heaptoma cells in vitro.In vivo. only antisense S-ODNs exhibitedobvious antitumor activities. FACS analysisrevealed that the growth inhibition by antisenseS. ODNs was associated with their cell apoptosisinduction.CONCLUSION Antisense S-ODNs targeted toAFP genes inhibit the growth of human hepatomacells and solid hepatoma, which is related totheir cell apoptosis induction. | Xing Wang Wang~1 Jin Hui Yuan~1 Ru Gang Zhang~1 Li Xia Guo~1 Yong Xie~2 Hong Xie~1 ~1Department of Biotherapy,Shanghai Institute of Cell Biology,Chinese Academy of Sciences,Shanghai 200031,China ~2Department of Biology,Hong Kong University of Science and Technology,ChinaDr.Xing Wang Wang earned Ph.D.from Shanghai Institute of Materia Medical,Chinese Academy of Sciences in 1997.Now a professor at Shanghai Institute of Cell Biology,Chinese Academy of Sciences. | 2001 | World Journal of Gastroenterology2001，7，3： | 21 |
| 7 | The formation mechanism of high-quality dolomite reservoir in the deep of Puguang Gas Field显示文摘The discovery of Puguang Gas Field provides the exploration of China deep marine carbonate rock with important references.In Puguang Gas Field,the dolomite reservoirs discovered in the deep are the best in the present of China,which present big thickness and wide-range distribution,and develop abundant secondary porosity.The researches show that Puguang Gas Field bears the characteristics of early gas-filling time,deep burial,high matured organic matter and long-term interaction of hydrocarbon(oil and gas)-water-rock(carbonate reservoir).The developments of secondary pores in this area are affected by multiple diagenesis and their formation mechanisms are complicated.Through the research on depositional environment,sedimentary facies and reservoir porosity characters of Changxing and Feixianguan Formations,it is thought that high-quality dolomite reservoirs of Puguang Gas Field form on the favorable sedimentary facies belts,which are the integrate result affected by several factors including superficial corrosion,burial corrosion,overpressure and tectonic movement,among which burial corrosion of TSR to reservoir and overpressure formed by thermal evolution of organic matter have great effect on the formation of secondary porosity of Changxing and Feixianguan Formations. | MA YongSheng 1 ,GUO TongLou 1 ,ZHAO XueFeng 2 &CAI XunYu 1 1 Southern Exploration&Production Company,Sinopec,Kunming 650200,China 2 China University of Mining and Technology,Beijing 100083,China | 2008 | Science China Earth Sciences2008，51，S1： | 19 |
| 8 | In vitro production of TNFα,IL-6 and sIL-2R in Chinese patients with ulcerative colitis显示文摘InvitroproductionofTNFα,IL6andsIL2RinChinesepatientswithulcerativecolitisXIABing1,GUOHaiJian1,JBACrusius2,DENGChangSheng... | XIA Bing 1, GUO Hai Jian 1, JBA Crusius 2, DENG Chang Sheng 1, SGM Meuwissen 2 and AS Pena 2 | 1998 | World Journal of Gastroenterology1998，4，3： | 18 |
| 9 | Zircon and apatite fission track analyses on mineralization ages and tectonic activities of Tuwu-Yandong porphyry copper deposit in northern Xinjiang, China显示文摘The mineralization ages reported in the past in the Tuwu-Yandong copper district not only are different,but also fall into the Hercynian epoch.This study has achieved 9 zircon and 7 apatite fission track analysis results.The zircon fission track ages range from 158 Ma to 289 Ma and the apatite ages are between 64 Ma and 140 Ma.The mineralization accords with the regional tectonics in the copper district.We consider that the zircon fission track age could reveal the mineralization age based on annealing zone temperature of 140―300℃ and retention temperature of ~250℃ for zircon fission track,and metallogenetic temperature of 120―350℃ in this ore district.Total three mineralization epochs have been identified,i.e.,289―276 Ma,232―200 Ma and 165―158 Ma,and indicate occurrence of the min-eralization in the Indosinian and Yanshan epochs.Corresponding to apatite fission track ages,the three tectonic-mineralizing epochs are 140―132 Ma,109―97 Ma and 64 Ma,which means age at about 100℃ after the mineralization.The three epochs lasted 146 Ma,108 Ma and about 100 Ma from ~250℃ to ~100℃ and trend decrease from early to late.It is shown by the fission track modeling that this district underwent three stages of geological thermal histories,stable in Cretaceous and cooling both before Cretaceous and after 20 Ma. | YUAN WanMing1,BAO ZengKuan2,DONG JinQuan2,GUO ZhaoJie3 & DENG Jun1 1 State Key Laboratory of Geological Processes and Mineral Resources,China University of Geosciences,Beijing100083,China 2 Laboratory of Nuclear Analysis Techniques,Institute of High Energy Physics,Chinese Academy of Sciences,Beijing 100039,China 3 Department of Geology,Peking University,Beijing 100871,China | 2007 | Science China Earth Sciences2007，50，12： | 16 |
| 10 | Regulation of salt and ABA responses by CIPK14, a calcium sensor interacting protein kinase in Arabidopsis显示文摘Calcium and protein kinase serve as the common mediators to regulate plant responses to multiple stresses including salt and ABA stimulus. Here we reported a novel protein kinase (CIPK14) that regulated the responses to ABA treatment and salt stress in Arabidopsis. CIPK14 transcripts, capable been checked in roots, stems, leaves and flowers, were highly expressed in flowers and roots. CIPK14 was induced by ABA and salt treatments. The disruption of CIPK14 altered the transcriptional pattern of a gene marker line related to ABA and salt responses, and the results suggested that CIPK14 probably was responsible to the control of the salt and ABA responses. Comparing with wild types, the lines inserted with the T-DNA in which CIPK14 gene expression was knocked out were also more sensitive to ABA and salt stimulus, showing low germination rate and the less root elongation. While, when these conditioned seeds were treated with norflurazon, their germination percentages could recover to a certain extent. We also found that exogenous calcium could have an effect on the transcription of CIPK14 under ABA and salt treatments, and it seemed that calcium ion might work upstream CIPK14 to regulate the plant response to ABA and salt response. | QIN YuZhi1,2, LI Xu1, GUO Ming1, DENG KeQin1, LIN JianZhong1, TANG DongYing1, GUO XinHong1 & LIU XuanMing1 1 College of Life Science and Biotechnology, Bioenergy and Biomaterial Research Center, Hunan University, Changsha 410082, China 2 College of living resources & Environment Science, Jishou University, Jishou 416000, China | 2008 | Science China(Life Sciences)2008，51，5： | 16 |
| 11 | Relationship between Fas/ FasL expression and apoptosis of colon adenocarcinoma cell lines显示文摘INTRODUCTIONFas/ FasL system has been identified as a keymediator of apoptosis in tumor cells[1-4]. Theoccurrence and development of neoplasm are closelyrelated to apoptosis[5-7] Most chemotherapeuticdrugs kill cancer cells mainly by inducingapoptosis[8-14].' | Zhi Hai Peng Tong Hai Xing Guo Qiang Qiu Hua Mei Tang Shanghai No. 1 People’s Hospital, Shanghai 200080, China | 2001 | World Journal of Gastroenterology2001，7，1： | 15 |
| 12 | Enhancing aerodynamic performances of a high-turning compressor cascade via boundary layer suction显示文摘Experimental investigation was carried out to study the effect of suction positions and suction flow rates on the aerodynamic performance of a compressor cascade with a large camber angle. The ink-trace flow visualization was conducted and the flow fields of the cascade were also measured. Three types of boundary layer suction configurations are compared,i.e. the suction surface suction,the endwall suction and the compound suction. Experimental results show that the large amount of suction flow rate gains more losses reduction than the small amount for a certain proper suction configuration,but the speed of loss decline slows down as the suction flow rate goes on increasing. Boundary layer suction on the suction surface obviously enhances the ability of the boundary layer around the midspan to withstand the negative pressure gradient of the flow passage. The range of the suction surface corner is also decreased. If the suction slot locates in the corner separation region where severe separation has happened,the flow separation will be terminated at the slot and redevelop downstream. And boundary layer suction on the endwall mainly influences the endwall corner region in remarkably delaying,lessening and reorganizing the corner separation. While the whole flow field is remarkably improved at both midspan and the corner region in the compound suction schemes. At higher suction flow rates,the aerodynamic performance of the compressor cascade is better than that with boundary layer suction simply on the suction surface or on the endwall. When the suction flow rate is 1.5% of the inlet mass flow,the compound suction scheme achieves a maximum loss reduction of 17% compared with the cascade without boundary layer suction. | GUO Shuang1, CHEN ShaoWen1, LU HuaWei2, SONG YanPing1 & CHEN Fu1 1 School of Energy Science and Engineering, Harbin Institute of Technology, Harbin 150001, China 2 Marine Engineering College, Dalian Maritime University, Dalian 116026, China | 2010 | Science China(Technological Sciences)2010，53，10： | 14 |
| 13 | A hybrid model for numerical wave forecasting and its implementation-Ⅰ.The wind wave model显示文摘The authors make an endeavor to explain why a new hybrid wave model is here proposed when several such models have already been in operation and the so- called third generation wave modej is proving attractive. This part of the paper is devoted to the wind wave model. Both deep and shallow water models have been developed, the former being actually a special case of the latter when water depth is great. The deep water model is exceptionally simple in form. Significant wave height is the only prognostic variable. In comparison with the usual methods to compute the energy input and dissipations empirically or by 'tuning', the proposed model has the merit that the effects of all source terms are combined into one term which is computed through empirical growth relations for significant waves, these relations being, relatively speaking, easier and more reliable to obtain than those for the source terms in the spectral energy balance equation. The discrete part of the model and the implementation of the | Wen Shengchang (S.C. Wen)1, Zhang Dacuo, Chen Bohai and Guo Peifang Institute of Physical Oceanography, Ocean University of Qingdao (Formerly, Shandong College of Oceanography), Qingdao, China | 1989 | Acta Oceanologica Sinica1989，8，1： | 14 |
| 14 | Complete nucleotide sequence of a novel porcine circovirus-like agent and its infectivity in vitro显示文摘A novel agent (hence termed as P2) was isolated from pig sera in China, which contained covalently bound circular genomic DNAs of 993 nucleotides. Sequence analyses indicated that the agent was closely related to the porcine circovirus (PCV). The molecular clone of P2 was constructed subsequently and used for the following studies. Intracytoplasmic inclusions and intranuclear inclusions were only found in PK-15 cells transfected with the tandem dimer of P2 molecular DNA clone. Intracytoplasmic inclusions were round or irregular in shape and 0.1-0.4 μm in diameter, and intranuclear inclusions were electronically denser than intracytoplasmic inclusions and had two general shapes: round/small (0.1 μm in diameter) and hexagonal/large (0.5―1.4 μm in diameter). The inclusions were not membranously bound. The cells transfected with the tandem dimer of P2 molecular DNA clone were tested positive for P2 DNA at passages 5. The P2 antigen could be detected in both transfected and passaged PK-15 cells. This is the first report regarding the complete nucleotide sequence of a small DNA genome in a circovirus-like infectious agent in vitro. | WEN LiBin1, HE KongWang1, YANG HanChun2, NI YanXiu1, ZHANG XueHan1, GUO RongLi1 & PAN QunXin1 1 Key Laboratory of Animal and Poultry Diseases Diagnostic of the Ministry of Agriculture, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China 2 Key Laboratory of Preventive Veterinary Medicine of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China | 2008 | Science China(Life Sciences)2008，51，5： | 14 |
| 15 | Enrichment mechanisms of rare earth elements in marine hydrogenic ferromanganese crusts显示文摘A series of selective extraction experiments were conducted on marine hydrogenic ferromanganese crusts from the seamount near the Line Island to investigate the distribution of rare earth elements(REEs) and the mechanisms of combination between REEs and the hydrogenic ferromanganese crusts.The enrichment of REEs in hydrogenic ferromanganese crusts is attributed mainly to the mineral or oxide/hydroxide of the crust rather than the growth environment.The REEs are present mainly in amorphous ferric oxide/hydroxide rather than in δ-MnO2.Amorphous ferric oxide/hydroxide preferentially combines free REE3+,while δ-MnO2 combines the REE-carbonate complexes in modern seawater.The REEs in seawater are combined more strongly with amorphous ferric oxide/hydroxides than with δ-MnO2.The positive Ce anomaly in hydrogenic ferromanganese crusts results from the oxidation of soluble Ce3+ to insoluble Ce4+ by the actively soluble oxygen of the bottom current rather than by the oxidation of δ-MnO2. | JIANG XueJun1,2,LIN XueHui1,2,YAO De3,4 & GUO WeiDong5 1 Key Laboratory of Marine Oil and Gas Resources and Marine Environment,Ministry of Land and Resources,Qingdao 266071,China 2 Qingdao Institute of Marine Geology,China Geological Survey,Qingdao 266071,China 3 Institute of Resources and Environment,Shandong University of Technology,Zibo 255049,China 4 Institute of Oceanology,Chinese Academy of Sciences,Qingdao 266071,China 5 Department of Oceanography,Xiamen University,Xiamen 361005,China | 2011 | Science China Earth Sciences2011，54，2： | 14 |
| 16 | Preliminary study on the production of transgenic mice harboring hepatitis B virus X gene显示文摘INTRODUCTIONDespiteoverwhelmingepidemiologicalevidencelinkingpersistentHepatitisBVirus(HBV)infectionandthedevelopmentofhepato... | ZHU Huan Zhang 1, CHENG Guo Xiang 2, CHEN Jian Qu 2, KUANG Shu Yuan 3, CHENG Yong 2, ZHANG Xin Li 1, Ll Hou Da 2, XU Shao Fu 2, SHI Jing Quan 1, QIAN Geng Sun 3 and GU Jian Ren 3 | 1998 | World Journal of Gastroenterology1998，4，6： | 14 |
| 17 | Orbit determination for geostationary satellites with the combination of transfer ranging and pseudorange data显示文摘Geostationary satellites(GEOs) play a significant role in the regional satellite navigation system.Simulation experiments show that the clock corrections could be mitigated through a single strategy or double differencing strategies for a navigation constellation,but for the mode of individual GEO orbit determination,high precision orbit and clock correction could not be obtained in the orbit determination based on the pseudorange data.A new GEO combined precise orbit determination(POD) strategy is studied in this paper,which combines pseudorange data and C-band transfer ranging data.This strategy overcomes the deficiency of C-band transfer ranging caused by limited stations and tracking time available.With the combination of transfer ranging and pseudorange data,clock corrections between the GEO and the stations can be estimated simultaneously along with orbital parameters,maintaining self-consistency between the satellite ephemeris and clock correction parameters.The error covariance analysis is conducted to illuminate the contributions from the transfer ranging data and the psudoranging data.Using data collected for a Chinese GEO satellite with 3 C-band transfer ranging stations and 4 L-band pseudorange tracking stations,POD experiments indicate that a meter-level accuracy is achievable.The root-mean-square(RMS) of the post-fit C-band ranging data is about 0.203 m,and the RMS of the post-fit pseudorange is 0.408 m.Radial component errors of the POD experiments are independently evaluated with the satellite laser ranging(SLR) data from a station in Beijing,with the residual RMS of 0.076 m.The SLR evaluation also suggests that for 2-h orbital predication,the predicted radial error is about 0.404 m,and the clock correction error is about 1.38 ns.Even for the combination of one C-band transfer ranging station and 4 pseudorange stations,POD is able to achieve a reasonable accuracy with the radial error of 0.280 m and the 2-h predicted radial error of 0.888 m.Clock synchronization between the GEO and tracking stations is achieved with an estimated accuracy of about 1.55 ns,meeting the navigation service requirements. | GUO Rui1,2,3,4,HU XiaoGong2,4,LIU Li1,WU XiaoLi1,HUANG Yong2,4 & HE Feng1 1 Beijing Global Information Application and Development Center,Beijing 100094,China 2 Shanghai Astronomical Observatory,Chinese Academy of Sciences,Shanghai 200030,China 3 Graduate University of Chinese Academy of Sciences,Beijing 100049,China 4 Space Navigation and Positioning Technology,Laboratory of Shanghai Municipal,Shanghai 200030,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，9： | 13 |
| 18 | Experimental study on mechanism and protection of stress ulcer produced by explosive noise显示文摘INTRODUCTIONExplosivenoisemayproduceanenormousadverseeffectonhumanbodyandmind.Ithasbeenknownthatpepticulceroccuredmuchmorefre... | LIU Guo Shi 1, HUANG Yu Xin 1, LI Shuan Wei 2, PAN Bo Rong 3, WANG Xin 1, SUN Da Yong 1 and WANG Qing Li 1 | 1998 | World Journal of Gastroenterology1998，4，6： | 13 |
| 19 | Meso-scale circulation at the intermediate-depth east of Mindanao observed by Argo profiling floats显示文摘The meso-scale circulation at the intermediate depth east of Mindanao is studied using Argo profiling floats observations. The trajectories and the parking-depth velocities of Argo floats show that the intermediate-depth circulation east of Mindanao contains significant meso-scale features that are highly variable both in space and in time. Both cyclonic and anticyclonic eddies at the intermediate depth (1000–2000 m) are indicated by the trajectories east of Mindanao. The mean tangential velocities of these eddies are about 10 cm/s at 2000 m and over 20 cm/s at 1000 m, which indicates that the geostrophic calculation may contain large errors due to the vigorous eddy activity at the reference levels. The analyses also suggest that these eddies might play an important role in mass and vorticity balances of the intermediate-depth circulation east of Mindanao. | ZHOU Hui1, YUAN DongLiang1, GUO PeiFang2, SHI MaoChong2 & ZHANG QiLong 1 Key Laboratory of Ocean Circulation and Wave Studies, Chinese Academy of Sciences, Qingdao 266071, China 2 Physical Oceanography Laboratory, Ocean University of China, Qingdao 266100, China | 2010 | Science China Earth Sciences2010，53，3： | 12 |
| 20 | Ectopic expression of a hyacinth AGL6 homolog caused earlier flowering and homeotic conversion in Arabidopsis显示文摘MADS-box genes are involved in floral organ development. Here we report that an AGL6(Agamous-like 6)-like MADS-box gene, HoAGL6, was isolated from Hyacinthus orientalis L. Expression pattern analy-sis demonstrated that HoAGL6 transcript was detected in inflorescence buds, tepals, carpels and ovules, but not in stamina, leaves or scales. Transgenic Arabidopsis plants ectopically expressing HoAGL6 exhibited novel phenotypes of significantly reduced plant size, extremely early flowering, and losing inflorescence indeterminacy. In addition, wide homeotic conversion of sepals, petals, and leaves into carpel-like or ovary structures, and disappearance or number reduction of stamens in 35S::HoAGL6 Arabidopsis plants were also observed. RT-PCR analysis indicated that the expressions of flowering time gene SOC1 and flower meristem identity gene LFY were significantly up-regulated in 35S::HoAGL6 transgenic Arabidopsis plants, and the expression levels of floral organ identity genes AG and SEP1 in leaves were also elevated. These results indicated that HoAGL6 was involved in the regulation of flower transition and flower organ formation. | FAN JinHui1, LI WenQing2, DONG XiuChun1, GUO Wei1 & SHU HuaiRui3 1 College of Forestry, Shandong Agricultural University, Taian 271018, China 2 College of Biological Science, China Agricultural University, Beijing 100094, China 3 College of Horticulture Science and Engineering, Shandong Agricultural University, Taian 271018, China | 2007 | Science China(Life Sciences)2007，50，5： | 12 |
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