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| 1 | GATA-3 promotes Th2 responses through three different mechanisms: induction of Th2 cytokine production, selective growth of Th2 cells and inhibition of Thl cell-specific factors显示文摘 | Jinfang Zhu Hidehiro Yamane Javier Cote-Sierra Liying Guo William E Paul | 2006 | Cell Research2006，16，1： | 48 |
| 2 | Chinese Economic Structure and SDA Model | CHEN Xi\|kang 1,\ GUO Ju\|e 2 1. Academy of Machemation and Systems Science, Chinese Academy of Science Beijing 100080, China 2. Shaanxi Institute of Finance and Economics, Xi′an 710061, China | 2000 | Systems Science and Systems Engineering2000，10，2： | 40 |
| 3 | Relationship of Helicobacterpylori eradication with gastric cancer and gastric mucosal histological changes: a 10-year follow-up study显示文摘 | Zhou Liya Lin Sanren Ding Shigang Huang Xuebiao Jin Zhu Cui Rongli Meng Lingmei Li Yuan Zhang Li Guo Changji Xue Yan Yan Xiu'e Zhang Jing | 2014 | Chinese Medical Journal2014，，8： | 28 |
| 4 | Pupillary response in patients receiving intrathecal sufentanil显示文摘Pupillary constriction occurs with intravenousadministration of opioids such as sufentanil.However,few studies have investigated the pupillaryeffects of intrathecal(IT)sufentanil.It has previouslybeen demonstrated that the cephalad spread within thecerebrospinal fluid of IT sufentanil results in sideeffects.There are two principal findings of the presentstudy:(1)spinal sufentanil combined with low-dose ofbupivacaine in patients with lower abdominal or lowerextremity procedures induces a dose-dependent pupillaryconstriction that is far more sensitive than othercentrally-mediated side effects;(2)the pupillary effect ofIT sufentanil correlates closely with the adequacy ofspinal anesthesia. | WANG Yi-chun GUO Qu-lian WANG E ZHONG Tao HUANG Chang-sheng PENG Jing | 2007 | Chinese Medical Journal2007，，14： | 14 |
| 5 | Intraoperative cardiac arrest during anesthesia: a retrospective study of 218 274 anesthetics undergoing non-cardiac surgery in a US teaching hospital显示文摘背景耐心的安全更被获得了在最近的 years.The 作者的注意考察了在在匹兹堡大学医学中心经历在1989年1月和2001年12月之间的 noncardiac 外科的操作房间里有心脏的拘捕的病人,学习的 USA.The 主要目的是决定 intraoperative 的发生心脏的拘捕,识别心脏的拘捕的可能的原因并且由匹兹堡大学与赞同探索顺从的 modifications.Methods | AN Jian-xiong Li-Ming Zhang Erin A. Sullivan GUO Qu-lian John E Williams | 2011 | Chinese Medical Journal2011，，2： | 9 |
| 6 | Preconditioning of intravenous parecoxib attenuates focal cerebral ischemia/reperfusion injury in rats显示文摘 | WANG Na GUO Qu-lian YE Zhi XIA Ping-ping WANG E YUAN Ya-jing | 2011 | Chinese Medical Journal2011，，13： | 9 |
| 7 | SF_6断路器的热开断性能的数值预测(英文)显示文摘The design technology for HV SF6 gas circuit breakers is very demanding.A numerical method for prediction of the thermal interruption capability of SF6 gas circuit breakers is established based on the two-dimensional magneto-hydrodynamic(MHD) model and a commercial CFD(computational fluid dynamics) software,FLUENT.Nozzle ablation effect is considered by introducing an independent mass conservation equation for the ablated material to the overall conservation equations of mass,momentum,and energy.The ohmic heating and the radiation of the electric arc are considered in the model by adding relevant source terms.To predict the thermal interruption capability,the arc conductance 200 ns before current zero is used as an indicator.The CFD model is applied for the high current arcing phase,and Mayr arc model is used near the current zero period.The arc conductance at 200 ns before current zero(G200) for various arcing periods are computed by the present method.It shows that there exist a limit of the G200.For those whose arcing periods are within the arcing window,the related G200 are below the limit,therefore result a successful current interruption,and vice versa.The validation of the developed computer simulation tool is therefore verified.The numerical prediction by the simulation tool is verified by the direct interrupting test of 550 kV gas circuit breaker(GCB).The developed computer simulation tool was applied in the design of a 550 kV GCB.Significant benefits have been achieved in terms of both the cost saving and shorten of the development cycle. | MU Jingwei GUO Jin DENG Xiang'e | 2013 | 高电压技术2013，39，4： | 6 |
| 8 | Toxicity of Graphene Quantum Dots in Zebrafish Embryo显示文摘Objective To evaluate the bio-safety of graphene quantum dots(GQDs), we studied its effects on the embryonic development of zebrafish. Methods In vivo, biodistribution and the developmental toxicity of GQDs were investigated in embryonic zebrafish at exposure concentrations ranging from 12.5-200 μg/m L for 4-96 h post-fertilization(hpf). The mortality, hatch rate, malformation, heart rate, GQDs uptake, spontaneous movement, and larval behavior were examined. Results The fluorescence of GQDs was mainly localized in the intestines and heart. As the exposure concentration increased, the hatch and heart rate decreased, accompanied by an increase in mortality. Exposure to a high level of GQDs(200 μg/mL) resulted in various embryonic malformations including pericardial edema, vitelline cyst, bent spine, and bent tail. The spontaneous movement significantly decreased after exposure to GQDs at concentrations of 50, 100, and 200 μg/mL. The larval behavior testing(visible light test) showed that the total swimming distance and speed decreased dose-dependently. Embryos exposed to 12.5 μg/mL showed hyperactivity while exposure to higher concentrations(25, 50, 100, and 200 μg/mL) caused remarkable hypoactivity in the light-dark test. Conclusion Low concentrations of GQDs were relatively non-toxic. However, GQDs disrupt the progression of embryonic development at concentrations exceeding 50 μg/mL. | WANG Zhen Guo ZHOU Rong JIANG Dan SONG Jing E XU Qian SI Jing CHEN Yun Ping ZHOU Xin GAN Lu LI Jian Zhen ZHANG Hong LIU Bin | 2015 | Biomedical and Environmental Sciences2015，28，5： | 6 |
| 9 | Comparison of physiological responses to oxidative and heavy metal stress in seedlings of rice paddy, Oryza sativa L.显示文摘Physiological responses on the bases of activities of antioxidant enzymes: peroxidase, catalase, superoxide dismutase and glutathione reductase as well as estimation of total protein, lipid peroxidation and thiols in the form of protein, non\|protein, glutathione and phytochelatin measured in growing seedlings of paddy, Oryza sativa L., from day 2 to 8 were compared following treatment of seeds for 5h with oxidative agents, paraquat 5 × 10 -5 , 10 -4 , 10 -3 mol/L, H 2O 2 10 -3 , 5×10 -3 , 10 -2 mol/L, and CdCl 2 10 -5 , 10 -4 , 5×10 -3 mol/L. A significant induction of all antioxidant enzymes along with an increase in the levels of protein, lipid peroxidation and glutathione was noted in response to oxidative stress, CdCl 2 induced significant peroxidase and catalase activities but not superoxide dismutase. In a marked contrast from oxidative stress, CdCl 2 decreased glutathione reductase activity as well as glutathione levels but increased phytochelatin level. The different physiological responses thus underlined the crucial involvement of glutathione and phytochelatin in the oxidative and heavy metal\|linduced adaptive responses respectively. | YU Guo\|ying, WANG Guo\|ping, HE Chi\|quan (Lab for Wetland Process and Environment, Changchun Institute of Geography, The Chinese Academy of Sciences, Changchun 130021,China E\|mail: yuguoying@mail.ccig.ac.cn) | 2000 | Journal of Environmental Sciences2000，12，4： | 5 |
| 10 | Synergistic antitumor efficiency of docetaxel and curcumin against lung cancer显示文摘Curcumin (淫液) ,主要 polyphenolic curcuminoid,从沉金根茎姜黄 longa 获得了,最近被报导在 vitro 并且在 vivo 有潜在的 antitumor 效果。Docetaxel (文档) 为非小的房间肺癌症的治疗被认为化疗同样首要。这里,我们第一次报导淫液能 synergistically 提高在里面 vitro 并且在对肺癌症的文档的 vivo antitumor 功效。在当前的学习,联合索引(CI ) 在 vitro 并且在 vivo 研究是打算的在里面决定在淫液和文档之间的相互作用。在里面在里面 vitro cytotoxicity 测试,中等效果的分析清楚地在某些集中显示了在淫液和文档之间的一个 synergistic 相互作用。而且,在 vivo,评估进一步在确定的 A549 与由静脉内的交货独自一个的文档相比表明了淫液 + 文档的优异 anticancer 功效移植异种皮移植模型。结果证明淫液 synergistically 在 4 天起始的治疗以后立即增加了文档的功效。另外,淫液和文档的同时的管理几乎没在治疗学的剂量包括骨头髓和肝显示出很少毒性到正常纸巾。因此,在 vitro 并且在 vivo,评估在传统的化疗对肺癌症和淫液的介绍表明了淫液和文档的令人满意的 synergistic antitumor 功效是阻止非小的房间肺癌症的传播的一个很有希望的方法。 | Haitao Yin Rui Guo Yong Xu Yulong Zheng Zhibo Hou Xinzheng Dai Zhengdong Zhang Donghui Zheng Hua'e Xu | 2012 | Acta Biochimica et Biophysica Sinica2012，44，2： | 4 |
| 11 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 12 | Prognostic value of perioperative leukocyte count in resectable gastric cancer显示文摘AIM: To investigate the prognostic significance of perioperative leukopenia in patients with resected gastric cancer.METHODS: A total of 614 eligible gastric cancer patients who underwent curative D2 gastrectomy and adjuvant chemotherapy were enrolled in this study. The relationship between pre- and postoperative hematologic parameters and overall survival was assessed statistically, adjusted for known prognostic factors.RESULTS: The mean white blood cell count(WBC) significantly decreased after surgery, and 107/614(17.4%) patients developed p-leukopenia, which was defined as a preoperative WBC ≥ 4.0 × 109/L and postoperative WBC < 4.0 × 109/L, with an absolute decrease ≥ 0.5 × 109/L. The neutrophil count decreased significantly more than the lymphocyte count. P-leukopenia significantly correlated with poor tumor differentiation and preoperative WBC. A higher preoperative WBC and p-leukopenia were independent negative prognostic factors for survival [hazard ratio(HR) = 1.602, 95% confidence interval(CI): 1.185-2.165; P = 0.002, and HR = 1.478, 95%CI: 1.149-1.902; P = 0.002, respectively] after adjusting for histology, Borrmann type, p TNM stage, vascular or neural invasion, gastrectomy method, resection margins, chemotherapy regimens, and preoperative WBC count. The patients with both higher preoperative WBC and p- leukopenia had a worse prognosis compared to those with lower baseline WBC and no p-leukopenia(27.5 mo vs 57.3 mo, P < 0.001). CONCLUSION: Preoperative leukocytosis alone or in combination with postoperative leukopenia could be independent prognostic factors for survival in patients with resectable gastric cancer. | Xiao-Feng Chen Jing Qian Dong Pei Chen Zhou Oluf Dimitri R?e Fang Zhu Shao-Hua He Ying-Ying Qian Yue Zhou Jun Xu Jin Xu Xiao Li Guo-Qiang Ping Yi-Qian Liu Ping Wang Ren-Hua Guo Yong-Qian Shu | 2016 | World Journal of Gastroenterology2016，22，9： | 4 |
| 13 | Effect of long-term fertilization on soil nitrate distribution显示文摘A thirteen years long term field fertilizer experiment was conducted to monitor the effect of different fertilization on soil nitrate distribution. The results showed: (1) Applying relative excessive N fertilizer could result large quantities of NO - 3 residue and NO - 3 movement downward in soil profiles; amending phosphate fertilizer or organic manure with nitrogen fertilizer together could significantly improve the status of NO - 3 leaching downward due to the balanced uptake of nutrients by crops. (2) Appropriate amounts of nitrogen fertilizer which was equal or smaller than the optimal fertilization rate could not result in more NO - 3 leaching in Northern China. (3) Precipitation influenced the amounts and depth of soil NO\+-\-3 leaching: NO - 3 could move to 80 cm depth or below at autumn or at the next spring when rainfall was higher during the rainy season through July to September in North China. | GUO Li ping *, ZHANG Fu suo, WANG Xing ren, MAO Da ru, CHEN Xin ping (Department of Plant Nutrition, China Agricultural University, Beijing 100094, China. E mail: guolp@ns.ami.ac.cn) | 2001 | Journal of Environmental Sciences2001，13，1： | 3 |
| 14 | Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented. | HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang | 2008 | Chinese Science Bulletin2008，53，16： | 2 |
| 15 | Optical field study of near-field optical recording with a solid immersion lens显示文摘 | Guo F Schlesinger T E Stancil D D | 2000 | Appl Opt2000，39，2： | 2 |
| 16 | Energy embodied in the international trade of China: An energy input–output analysis显示文摘 | Hongtao Liu Youmin Xi Ju’e Guo Xia Li | 2010 | Energy Policy2010，，8： | 2 |
| 17 | Stream water quality and its influencing factor in lower order streams in upriver sections of Ashihe River显示文摘为理解引起了水质的降级在的原因,更低的顺序流,系统的采样在 NortheastForestry 大学的 Maoershan 试验性的福雷斯特里沿着 Ashihe 河连续统的低顺序溪流(第 1st-5 ) 在不同空间地点被进行, Shangzhi 城市, Heilongjiang 省,中国。溪流水质的索引,即, pH ,溶解的氧(),混浊,温度,PO_4^(3-)-P,NO^(3-) -N andNH_4^+-N 集中,全部的溶解的无机的氮( TDIN-N ,包括集中ofNO_3^-- N 和 NH_4^+-N ),并且总计磷(无机、器官磷, TP )被测量并且分析。溪流顺序,相关环境背景和陆地使用类型为每个采样地点被记录。在有不同溪流订单和土地利用类型的不同地点的溪流水质的索引被 ANOVA 分析比较。在不同采样地点的溪流水质的索引被层次簇分析分析。水质有的 Resultshowed 在不同溪流订单和土地利用的重要差别打字;有不同溪流特征(溪流顺序和土地利用类型)的一些地点被组织进一样的簇,显示随机的骚乱在水质生产了变化,它与一般规则使溪流水质的空间变化不一致。 | GUO Bao-qin WANG Qing-cheng YU Hong-li Paul E Mou | 2005 | Journal of Forestry Research2005，16，3： | 2 |
| 18 | China’s provincial CO 2 emissions embodied in international and interprovincial trade显示文摘 | Ju’e Guo Zengkai Zhang Lei Meng | 2011 | Energy Policy2011，，： | 2 |
| 19 | 制药企业药品上市前安全风险管理显示文摘1药物警戒的必要性良好的药物警戒是最理想的药品风险管理方式,它可以最大程度的了解某种药品的所有信息,并且发现它潜在的安全问题,甚至有可能发现其预料之外的好处。鉴于这个理念,新化学实体(newchemical entity)在研发初期就必须进行动物和人体安全性测试,以便更好地促进并保护公众健康。中国古话所说的"是药三分毒", | Judith K Jones Elyse E Kingery Jing Tao Jeff J Guo | 2013 | 药物流行病学杂志2013，22，5： | 2 |
| 20 | Observation of quantum effects and coulomb blockade in silicon quantum- dot transistors at temperatures over 100K显示文摘 | Leobandung E Guo L G Wang Y | 1995 | Appl Phys Lett1995，67，7： | 2 |
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