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| 1 | SARS coronavirus entry into host cells through a novel clathrin- and caveolae-independent endocytic pathway显示文摘当严重急性呼吸症候群日冕病毒(SARS-CoV ) 开始被认为与质膜通过直接熔化进入房间时,更最近的证据建议那个病毒条目可以也包含 endocytosis。我们发现了那 SARS-CoV 进入房间经由 pH 依赖并且受体依赖者 endocytosis。有任何一个 SARS-CoV 尖铁蛋白质或忍受尖铁的假病毒的房间的治疗导致了变换血管收缩素的酶的 translocation 2 (ACE2 ) , SARS-CoV 的功能的受体,从房间表面到内涵体。另外,忍受尖铁的假病毒和 1 在内涵体被发现到 colocalize 的早内涵体抗原。用象 caveolin-1 colocalization 学习一样的特定的 endocytic 小径禁止者和主导否定的 Eps15 的进一步的分析建议那个病毒条目被 clathrin 独立、 caveolae 独立的机制调停。而且,在质膜的微域,它被显示出到为许多生理的发信号小径作为平台扮演的充满胆固醇、 sphingolipid 富有的类脂化合物木排,被显示涉及病毒入口。SARS-CoV 的 Endocytic 入口可以扩展这里的 SARS-CoV 感染,和我们的调查结果的细胞的范围贡献 SARS-CoV 致病的理解,为抗病毒的药研究提供新信息。 | Wang,H Yang,P Liu,K Guo,F Zhang,Y Zhang,G Jiang,C | 2008 | Cell Research2008，18，2： | 50 |
| 2 | Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function显示文摘在肿瘤和免疫系统之间的相互作用仍然糟糕被理解。重要临床的回答在对 CTLA4 和 PD-1/PD-L1 检查点与抗体对待的癌症病人被完成了;然而,仅仅病人的小部分对治疗作出回应,显示需要探索为癌症治疗的另外的 co 禁止的分子。B7-H3, B7 总科的一个成员,被我们以前显示出禁止 T 房间激活和 autoimmunity。在这研究,我们在肿瘤免疫分析了 B7-H3 的功能。B7-H3 的表示在多重肿瘤线,渗入肿瘤的树枝状的房间,和巨噬细胞被发现。与对抗抗体对待到 B7-H3 的 B7-H3-deficient 老鼠或老鼠显示出多重肿瘤的减少的生长,它取决于 NK 和 CD8 + T 房间。与细胞毒素的淋巴细胞表示的通常认为的受体, B7-H3 禁止了他们的激活,并且它的缺乏在忍受肿瘤的鼠标导致了增加的细胞毒素的淋巴细胞功能。B7-H3 和 PD-1 的联合封锁导致了迟了阶段的肿瘤的进一步提高的治疗学的控制。一起拿,我们的结果显示 B7-H3 检查点可以对癌症为免疫疗法用作一个新奇目标。 | Young-hee Lee Natalia Martin-Orozco Peilin Zheng Jing Li Peng Zhang Haidong Tan Hyun Jung Park Mira Jeong Seon Hee Chang Byung-Seok Kim Wei Xiong Wenjuan Zang Li Guo Yang Liu Zhong-jun Dong Willem W Overwijk Patrick Hwu Qing Yi Larry Kwak Zhiying Yang Tak W Mak Wei-Li Laszlo G Radvanyi Ling Ni Dongfang Liu Chen Dong | 2017 | Cell Research2017，27，8： | 29 |
| 3 | 高光谱遥感在农作物长势监测中的应用显示文摘该研究是加拿大Saskatchewan Scott农作物轮作系统(ACS)研究的一部分。研究始于1994年,历时18a,评价9个可耕种农作物产量系统的可靠性。由3种处理水平(organic,reduced,high)和3种作物多样性水平(low,diversified annual grains,diversified annual perennials)结合而产生的9个农作物产量系统,被用于监测和评价加拿大牧场不同处理和不同作物种植轮作下可耕种农作物的产量。在2003年生长季共收集了3次叶面积指数和光谱反射率的数据:生长季前期(6月)、生长季旺盛期(7月)、生长季后期(8月)。叶面积指数是由LAI-2000植物冠层分析仪监测的,光谱测量是由覆盖了350-2500 nm波长范围共2215个波段的ADS便携式高光谱仪完成的。结果显示,光学测量可以用于监测农作物生长状况的差异。从生长季的早期到中期,光谱和叶面积指数在不同处理下有显著差异。7月中期是用遥感资料监测农作物长势的最佳季节;红光波段与近红外波段反射率的比值和基于这两个波段构造的归一化植被指数,是检测农作物长势的最佳植被指数。 | 郑有飞 Guo X Olfert O Brandt S Thomas G Weiss R Sproule L | 2007 | 气象与环境科学2007，30，1： | 22 |
| 4 | Association of N-terminal pro-brain natriuretic peptide with the severity of coronary artery disease in patients with normal left ventricular ejection fraction显示文摘 | Wu NQ Guo YL Li XL Liu J Qing P Xu RX Zhu CG Jia Y J Liu G Dong Q Jiang LX Li J J Ma FL | 2014 | Chinese Medical Journal2014，，4： | 23 |
| 5 | Sm-Nd isotopic age and genesis of gabbro xenoliths in Daoxian County, Hunan Province显示文摘MANY geologists pay attention to Mesozoic tectonomagmatic activity and the associating multi-metal ore deposits in South China. However, the age of the transformatiori of tectonic regimein the area is little studied. Occurrence of gabbro xenoliths in Mesozoic alkaline basalts inDaoxian region, Hunan Province, shows that the lithosphere in the region was intensely ex-tended and thinned during the Mesozoic, followed by underplating of mantle-derived mag- | Guo, F Fan, WM Lin, G Lin, YX | 1997 | Chinese Science Bulletin1997，42，21： | 14 |
| 6 | 代谢健康的肥胖和腹型肥胖与高血压风险增加相关显示文摘代谢健康型肥胖是指具有正常代谢特征的肥胖人群。研究者在中国农村地区队列研究(the rural Chinese cohort study)的成年人中,探究了代谢健康型肥胖与高血压风险的关系。这项前瞻性队列研究纳入中国成人9137名,在基线时(2007-2008年)无高血压、2型糖尿病或血脂异常,在2013-2014年进行随访。 | 周卫(译) 袁源(审校) Zhao Y Qin P Sun HH Liu Y Liu D Zhou Q Guo C Li Q Tian G Wu X Hu D Sun X Zhang M | 2020 | 中华高血压杂志2020，28，9： | 7 |
| 7 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998，，2： | 4 |
| 8 | 用粘结剂-处理工艺制备高性能钢粉混合粉显示文摘FLOMET工艺是一种粘结剂-处理混合技术,其是用固态有机粘结剂将细小的石墨粉、金属添加剂及润滑剂颗粒粘结在较粗的铁粉颗粒上。和常规混合粉相比,粘结剂-处理混合粉的主要好处是,流动性较好,可提高生产率与零件的一致性,以及减小扬尘(dusting)与偏聚。这些特性都使粘结剂-处理的混合粉很适于生产高性能粉末冶金制品,以及其他各种用途需要优异充填特性的混合粉。QMP在20世纪90年代中期提出了一系列粘结剂-处理的混合粉。此后,为改进这类混合粉的性能和开发能用于特殊用途的粘结剂-处理混合粉一直在进行不懈的努力。本文评述了粘结剂-处理材料的物理性能,生坯与烧结体的性能。特别关注的是这些材料的生产工艺特性。 | Sylvain St-Laurent Claude Gélinas Ray Guo Yannig Thomas Lhoucine Azzi | 2007 | 粉末冶金工业2007，17，1： | 4 |
| 9 | Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer显示文摘 | Zhang XM Miao XP Liang G Hao BT Wang YG Tan W Li Y Guo YL He FC Wei QY Lin DX | 2006 | 中国生物学文摘2006，20，4： | 2 |
| 10 | WELDING BETWEEN HIGH MANGANESE STEEL AND HIGH CARBON STEEL显示文摘Manuscript received 30 July 1999 Abstract The shielded metal arc welding (SMAW) of a manganese steel part as a crossing of railway track to a carbon steel part as the rails of the railroad is the welding of dissimilar steel. It are was known that it is not possible to the the rail of railroad directly to the cross- ing of railway track made from a steel containing about 14% of manganese (wt. ) because of so many differences between the two kinds of steels such as composition, microstructure,mechanical properties and weldability.A method was used to solve the problem by presetting an intermediate layer on each side of the joint and other special procedures were used.The result of test indicated that a good weld joint was obtained. | M. H. Guo,D. C. Shao, Z. G Dong and J. C Yang National Key Laboratory Advanced Welding Production Technology, Harbin institute of Technology, Harbin 150001, China | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，1： | 2 |
| 11 | Influence of Eutrophication on the Distribution of Total Mercury and Methylmercury in Hydroelectric Reservoirs显示文摘 | Meng Bo Feng X B Chen C X Qiu G L Sommar J Guo Y N Liang P Wan Q | 2010 | EN2010，，5： | 2 |
| 12 | Robust nonlinear coordinated generator excitation and SVC control for power systems 显示文摘 | WANG Y Y TAN Y L GUO G X | 2000 | Electrical Power and Energy Systems2000，22，： | 2 |
| 13 | Observation of quantum effects and coulomb blockade in silicon quantum- dot transistors at temperatures over 100K显示文摘 | Leobandung E Guo L G Wang Y | 1995 | Appl Phys Lett1995，67，7： | 2 |
| 14 | Efficacy of Qigong for the treatment of alopecia universalis: a clinical case report显示文摘Qigong is a part of traditional Chinese medicine. According to the antique treaties, the foundations of traditional Chinese medicine are based in maintaining the harmony between Qi (energy), Jing (essence) and Shen (spirit). Alterations in this harmony can develop and determine the appearance of disease. Therapeutic effects of Qigong are helpful in the prevention and treatment of several diseases. It's main role in restoring body functions is due to the communication between internal organs, tissues and cells. The main goal of this work is to show the efficacy of Qigong in the treatment of a dermatological disease characterized by the appearance of circular or oval patches of missing hair, known as alopecia universalis. For western medicine the exact cause of this illness is not totally revealed, however, it's attributed to psycological, genetics and metabolic alterations. From the traditional Chinese medicine perspective, hair alterations are framed in the area of the water energy, represented by the kidney organ. The results of Qigong treatment suggested that the cranial hair follicles had been activated since the first treatment. As treatment progressed, the cranial hair follicles continued to grow, what's more, the brightness and pigmentation of the hair also increased. Therefore, in the clinical conditions evaluated, Qigong could be an effective alternative treatment in consideration of the visible evidence about rapid and long lasting results. Besides, we did not observe any side effects of Qigong in this case. | Gómez Jensen Alberto Alejandro Martínez Diana Elina Wan Qing Guo | 2019 | Life Research2019，2，1： | 2 |
| 15 | High-performance liquid chromatography coupled with coulometric array detection of electroactive components in fruits and vegetables: relationship to oxygen radical absorbance capacity 显示文摘 | Guo C Cao G Sofic E | 1997 | J Agric Food Chem1997，45，： | 1 |
| 16 | Seasonal variation of solvent extractable organic compounds in the aerosols in Qingdao, China显示文摘 | Guo Z G Sheng L F Feng J L | 2003 | Atmospheric Environment2003，37，13： | 1 |
| 17 | Toughening modification of PS with n-BA/MMA/styrene coreshell structured copolymer from emulsifier-free emulsion polymerization 显示文摘 | Guo T Y Tang G L Hao G J | 2003 | Journal of Applied Science2003，90，： | 1 |
| 18 | Mg-Ca-Zn bulk metallic glasses with high strength and significant ductility显示文摘 | GU X SHIFLET G J GUO F Q POON S J | 2005 | Journal of Materials Research2005，20，8： | 1 |
| 19 | Experiment on restrained steel beams subjected to heating and cooling 显示文摘 | Li G Q Guo S X | 2008 | Journal of Constructional Steel Research2008，64，3： | 1 |
| 20 | Stress corrosion cracking of pipeline steel in soil environments of eastern china显示文摘 | Li G F Huang C B Guo H | 2007 | Key Engineering Materials2007，，： | 1 |
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