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| 1 | The attractor of the stochastic generalized Ginzburg-Landau equation显示文摘The stochastic generalized Ginzburg-Landau equation with additive noise can be solved pathwise and the unique solution generates a random system.Then we prove the random system possesses a global random attractor in H01. | GUO BoLing~1 WANG GuoLian~(2+) Li DongLong~3 1 Institute of Applied Physics and Computational Mathematics,P.O.Box 8009,Beijing 100088,China 2 The Graduate School of China Academy of Engineering Physics,P.O.Box 2101,Beijing 100088,China 3 Department of Information and Computer Science,Guangxi University of Technology,Liuzhou 545006,China | 2008 | Science China Mathematics2008，51，5： | 11 |
| 2 | Advances in research into gamete and embryo-fetal origins of adult diseases显示文摘The fetal and infant origins of adult disease hypothesis proposed that the roots of adult chronic disease lie in the effects of adverse environments in fetal life and early infancy. In addition to the fetal period, fertilization and early embryonic stages, the critical time windows of epigenetic reprogramming, rapid cell differentiation and organogenesis, are the most sensitive stages to environmental disturbances. Compared with embryo and fetal development, gametogenesis and maturation take decades and are more vulnerable to potential damage for a longer exposure period. Therefore, we should shift the focus of adult disease occurrence and pathogenesis further back to gametogenesis and embryonic development events, which may result in intergenerational, even transgenerational, epigenetic re-programming with transmission of adverse traits and characteristics to offspring. Here, we focus on the research progress relating to diseases that originated from events in the gametes and early embryos and the potential epigenetic mechanisms involved. | Kexin Zou Guolian Ding Hefeng Huang | 2019 | Science China(Life Sciences)2019，62，3： | 7 |
| 3 | Generalized Predictive Control for Superheated Steam Temperature Regulation in a Supercritical Coal-fired Power Plant显示文摘The design and implementation of a Generalized Predictive Control(GPC)strategy for the superheated steam temperature regulation in a supercritical(SC)coal-fired power plant is presented.A Controlled Auto-Regressive MovingAverage(CARMA)model of the plant is derived from using the experimental data to approximately predict the plant’s future behavior.This model is required by the GPC algorithm to calculate the future control inputs.A new GPC controller is designed and its performance is tested through extensive simulation studies.Compared with the performance of the plant using a conventional PID controller,the steam temperature controlled by the GPC controller is found to be more stable.The stable steam temperature leads to more efficient plant operation and energy saving,as demonstrated by the simulation results.Plant performance improvement is also tested while the plant experiences the load demand changes and disturbances resulting from the malfunctioning of coal mills. | Mihai Draganescu Shen Guo Jacek Wojcik Jihong Wang Xiangjie Liu Guolian Hou Yali Xue Qirui Gao | 2015 | CSEE Journal of Power and Energy Systems2015，1，1： | 7 |
| 4 | A combination of follicle stimulating hormone, estradiol and age is associated with the pregnancy outcome for women undergoing assisted reproduction: a retrospective cohort analysis显示文摘To investigate the effect of basal hormone levels including follicle stimulating hormone(FSH) and estradiol(E2) and age on the pregnancy outcomes in women undergoing in vitro fertilization and embryo transfer(IVF-ET), we designed a retrospective cohort analysis and collected information of patients undergoing IVF between January 2014 and April 2017. We found that young women had much better pregnancy outcomes than older women regardless of the hormone levels. The pregnancy outcomes declined in young women with high basal E2, even though they had normal FSH. Older women with higher FSH had a worse outcome of pregnancy, especially with increased E2 level. The results suggest that a combination of FSH, E2 and age could effectively predict the pregnancy outcome for women undergoing IVF-ET, and we should encourage infertile women with diminished ovarian reserve, especially young infertile women, to try the assisted reproduction as early as possible. After 40-yearold, the cost-benefit ratio should be considered according to the ovarian function. | Ziru Jiang Li Jin Weihui Shi Ji Xi Yulian Hu Xinmei Liu Jianzhong Sheng Guolian Ding Hefeng Huang | 2019 | Science China(Life Sciences)2019，62，1： | 7 |
| 5 | miR-28-5p targets MTSS1 to regulate cell proliferation and apoptosis in esophageal cancer显示文摘Esophageal cancer (EC) is one of the most common aggressive malignant diseases worldwide. miR-28-5p plays important regulatory roles in many cancers including human EC. However, the molecular mechanism and potential role of miR-28-5p in EC remain uncertain. In this study, qRT-PCR and western blot analysis revealed that miR-28-5p expression was up-regulated and metastasis suppressor-1 (MTSS1) was down-regulated in EC tissues relative to matched para-cancer tissues. Cell counting kit-8 (CCK-8) assay demonstrated that miR-28-5p mimics increased cell viability, and miR-28-5p inhibitor decreased it. Flow cytometry (FCM) assay indicated that miR-28-5p mimics promoted cell cycle entry, while miR-28-5p inhibitor reduced it and induced cell apoptosis. Moreover, miR-28-5p mimics up-regulated the expressions of cyclin A, cyclin dependent kinase 2 (CDK2), cyclin D1, and cyclin E but down-regulated the expressions of cleaved caspase-3 and cleaved caspase-9, which was abolished by miR-28-5p inhibitor. Furthermore, luciferase reporter assay verified that miR-28-5p directly targeted MTSS1 3′UTR and down-regulated its expression. MTSS1 overexpression in TE-1 cells inhibited cell proliferation and promoted apoptosis induced by miR-28-5p mimics, whereas silencing of MTSS1 reversed cell progression induced by miR-28-5p inhibitor. We also demonstrated that miR-28-5p could promote esophageal tumor formation in vivo. Hematoxylin–eosin staining, immunohistochemistry, and TUNEL assays confirmed that miR-28-5p antagomir inhibited cell growth and accelerated apoptosis. Our results suggest that miR-28-5p may induce cell proliferation and suppress apoptosis to promote EC tumor formation via decreasing MTSS1 expression. Thus, miR-28-5p may be a potential target for human EC therapy. | Liang Zhang Xin Wang Xin Liu Mingyue Lv Erdong Shen Guolian Zhu Zhe Sun | 2020 | Acta Biochimica et Biophysica Sinica2020，52，8： | 5 |
| 6 | Mechanism underlying the retarded nuclear translocation of androgen receptor splice variants显示文摘As shown in our previous study, two alternatively spliced androgen receptor(AR) variants, which are exclusively expressed in the granulosa cells of patients with polycystic ovary syndrome, exhibit retarded nuclear translocation compared with wild-type AR. However, researchers have not yet determined whether these abnormalities correlate with heat shock protein 90(HSP90)and importin α(the former is a generally accepted co-chaperone of AR, and the latter is a component of classical nuclear import complexes). Here, these two variants were mainly retained in cytoplasm with HSP90 and importin α in the presence of dihydrotestosterone(DHT), and their levels in nucleus were significantly reduced, according to the immunofluorescence staining. The binding affinity of two AR variants for importin α was consistently decreased, while it was increased in WT-AR following DHT stimulation, leading to reduced nuclear import, particularly for the insertion-AR(Ins-AR). However, the binding affinities of two AR variants for HSP90 were increased in the absence of DHT compared with WT-AR, which functioned to maintain spatial structural stability, particularly for the deletion-AR(Del-AR). Therefore, the retarded nuclear translocation of two AR variants is associated with HSP90 and importin α, and the abnormal binding affinities for them play critical roles in this process. | Ye Liu Yinyu Wang Fangfang Wang Jiexue Pan Jingjing Xu Jingyi Li Chengliang Zhou Guolian Ding Yanting Wu Xinmei Liu Jianzhong Sheng Hefeng Huang | 2019 | Science China(Life Sciences)2019，62，2： | 4 |
| 7 | An Extension Matrix Approach to Chinese Character Recognition显示文摘 | Shu Wenhao Shi Daming Qian Guolian | 2006 | Proceedings of the IEEE2006，，8： | 1 |
| 8 | The asymptotic behavior of the stochastic Ginzburg-Landau equation with additive noise显示文摘 | WANG Guolian GUO Boling LI Yangrong | | 0，，： | 1 |
| 9 | Selective adsorption and separation of trace dissolved Fe(Ⅲ) from natural water samples by double template imprinted sorbcnt with chelating diamines 显示文摘 | Fazhi Xie Guijian Liu Fengchang Wu Guanghui Guo Guolian Li | 2012 | Chemical Engineering Journal2012，183，： | 1 |
| 10 | Vision-based Vehicle Tracking and Classification on the Highway显示文摘 | Guolian Yun Qimei Chen Bo Li Xindao Wang | 2007 | Journal of Systems Science and Information2007，5，2： | 1 |
| 11 | Dynamic modeling and multivariable control of organic rankine cycles in waste heat utilizing processes显示文摘 | Zhang Jianhua Zhang Wenfang Hou Guolian | 2012 | Computers & Mathematics With Applications2012，64，9： | 1 |
| 12 | Development and test of high efficiency WSF fluorescent converter for fast neutron radiography显示文摘 | GUOLiAn Zhang Guohui Zou Yubin | | 0，，： | 1 |
| 13 | Dynamic Modeling and Multivariable Control of Organic Rankine Cycles in Waste Heat Uti- lizing Processes显示文摘 | Jianhua Zhang Wenfang Zhang Guolian Hou | 2012 | Computers and Mathematics with Applications2012，，64： | 1 |
| 14 | Cyclin D1 G870A polymorphism and the risk of hepatocellular carcinoma in a Chinese population显示文摘 | Zhangyong Hu Zhipeng Zhou Guolian Xiong Yali Wang Yi Lai Lan Deng Jinliang Yang | 2014 | Tumor Biology2014，，6： | 1 |
| 15 | Dynamic modeling and multivariahle control of organic Rankine cycles in waste heat utilizing processes 显示文摘 | ZHANG Jianhua ZHANG Wenfang HOU Guolian | 2012 | Computers and Mathematics with Applications2012，64，5： | 1 |
| 16 | A low-virulence Eimeria intestinalis isolate from rabbit ( Oryctolagus cuniculus ) in China: molecular identification, pathogenicity, and immunogenicity显示文摘 | Tuanyuan Shi Guolian Bao Yuan Fu Xun Suo Lili Hao | 2014 | Parasitology Research2014，，3： | 1 |
| 17 | Effect of Donor KIR2DL1 Allelic Polymorphism on the Outcome of Pediatric Allogeneic Hematopoietic Stem-Cell Transplantation显示文摘 | Rafijul Bari Piya Rujkijyanont Erin Sullivan Guolian Kang Victoria Turner Kwan Gan Wing Leung | 2013 | Journal of Clinical Oncology2013，，30： | 1 |
| 18 | Study on the relationship between chronic tonsillitis and early stage of kidney failure显示文摘Objective: to investigate whether chronic tonsillitis is associated with early kidney failure;to analysis the reliability of urine microalbumin as a diagnostic indicator of chronic tonsillitis and early stage of kidney failure;either tonsillectomy is the effective way to prevent complications of chronic tonsillitis and early kidney failure. Methods: 84 patients with chronic tonsillitis who admitted to the department of Otorhinolaryngology, Qinghai University Affiliated Hospital from March 2012 to February 2013 were selected as subjects, 33 males and 51 females who aged between 7-55 years. It was divided into three group according to the course of disease, group A: duration is 1 to 3 years;group B: duration of 3 to 5 years;group C;duration> 5 years;in the immunological laboratory, 12 cases of normal control group were collected, male 7 cases , female 5 cases, aged 7 to 55 years old. The amount of microalbuminuria before and after operation was determined by turbidimetric method. The collected data were analyzed statistically. Results: There was no significant increase in urine microalbumin compared group A and control group, P> 0.05, the difference was not statistically significant. Group B and group C were significantly higher than those in the control group (P <0.05), the difference was statistically significant. The levels of microalbuminuria in group A pre-operation was significantly higher than that of in group C (P <0.05). The difference was statistically significant. The levels of microalbuminuria in group B were significantly higher than those in group C (P <0.05) during preoperation. The difference was statistically significant. The levels of microalbuminuria were significantly decreased in group A post-operation compared to the relatively group pre-operation, P <0.05, the difference was statistically significant. In group B, pre-operative and postoperative comparison, urine microalbumin was significantly decreased, P <0.05, the difference was statistically significant. The levels of microalbuminuria were significantly decreased in post-operative in group C than that of its pre-operation, P <0.05, the difference was statistically significant. Conclusion: Patients with chronic tonsillitis can be complicated by early stage of kidney failure. There is a certain clinical value of urine microalbumin used as a diagnostic indicator of chronic tonsillitis and early kidney failure, and its sensitivity gradually increased with the progress of disease. The only way to prevent the chronic tonsillitis complicated by early kidney failure is to do tonsillectomy. | Yuqin Hao Guolian Cui Qiuxia Zhou | 2018 | Insight-Chinese Medicine2018，1，1： | 0 |
| 19 | System identification under saturated precise or set-valued measurements显示文摘This paper considers the system identification problem based on saturated precise or set-valued measurements,which is widely used in various fields and has essential difficulties.Since existing methodologies cannot make full use of the mixed data,this paper is aiming to fill the gap and build a unified framework in dealing with such problems rigorously and comprehensively.New algorithms are introduced and their properties are established.Most significantly,the Cramécr-Rao(CR)lower bound based on the measurements is established,which consists of two parts with respect to the precise data and set-valued data,respectively.This prompts the idea of designing an estimation algorithm by grouping and combining the estimations under two classifications of data.As a result,a CR lower bound-based algorithm(CRBA)is constructed.The convergence properties are theoretically analyzed in terms of consistency and asymptotic efficiency under periodic inputs.For general inputs,an algorithm based on the CRBA that combines the expectation maximization(EM)algorithm for set-valued subsystems and the gradient descent algorithm for precise subsystems is proposed.Numerical simulations validate the superiority of the proposed algorithms. | Yanlong ZHAO Hang ZHANG Ting WANG Guolian KANG | 2023 | Science China(Information Sciences)2023，66，1： | 0 |
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