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| 1 | 肺结核病人低发现率的社会、经济影响因素研究显示文摘目的 找出重庆地区肺结核病人低发现率的社会经济影响因素,为提出有效的、适合重庆地区的病人发 现模式提供依据,努力提高病人发现水平。方法 本次研究主要采用了个人深入访谈、专题小组讨论、问题分析和矩阵 排序等多种定性研究的方法,对包括结核病现症病人、一般居民、结防专业机构的医护人员等进行了采访。结果 结核 病健康教育和宣传不足、结防专业机构实验室痰涂片检查能力不强、乡村医生业务素质不高等因素影响了肺结核病人的 发现工作。结论 必须采取有效的措施,加大宣传力度,普及防痨知识及落实有关防治政策;增加政府投入,加强结防专 业机构自身的建设;加强对基层医务人员的专业培训,才能够真正提高病人发现率。 | 汪洋 陈静 李颖 胡代玉 Lekha Gurung | 2005 | 中国卫生事业管理2005，21，1： | 22 |
| 2 | Prognostic value and nomograms of proximal margin distance in gastric cancer with radical distal gastrectomy显示文摘Objective:The proximal margin(PM)distance for distal gastrectomy(DG)of gastric cancer(GC)remains controversial.This study investigated the prognostic value of PM distance for survival outcomes,and aimed to combine clinicopathologic variables associated with survival outcomes after DG with different PM distance for GC into a prediction nomogram.Methods:Patients who underwent radical DG from June 2004 to June 2014 at Department of General Surgery,Nanfang Hospital,Southern Medical University were included.The first endpoints of the prognostic value of PM distance(assessed in 0.5 cm increments)for disease-free survival(DFS)and overall survival(OS)were assessed.Multivariate analysis by Cox proportional hazards regression was performed using the training set,and the nomogram was constructed,patients were chronologically assigned to the training set for dates from June 1,2004 to January 30,2012(n=493)and to the validation set from February 1,2012 to June 30,2014(n=211).Results:Among 704 patients with p TNM stage I,p TNM stage II,T1-2,T3-4,N0,differentiated type,tumor size≤5.0 cm,a PM of(2.1-5.0)cm vs.PM≤2.0 cm showed a statistically significant difference in DFS and OS,while a PM>5.0 cm was not associated with any further improvement in DFS and OS vs.a PM of 2.1-5.0 cm.In patients with p TNM stage III,N1,N2-3,undifferentiated type,tumor size>5.0 cm,the PM distance was not significantly correlated with DFS and OS between patients with a PM of(2.1-5.0)cm and a PM≤2 cm,or between patients with a PM>5.0 cm and a PM of(2.1-5.0)cm,so there were no significant differences across the three PM groups.In the training set,the C-indexes of DFS and OS,were 0.721 and 0.735,respectively,and in the validation set,the C-indexes of DFS and OS,were 0.752 and 0.751,respectively.Conclusions:It is necessary to obtain not less than 2.0 cm of PM distance in early-stage disease,while PM distance was not associated with long-term survival in later and more aggressive stages of disease because more advanced GC is a systemic disease.Different types of patients should be considered for removal of an individualized PM distance intra-operatively.We developed a universally applicable prediction model for accurately determining the 1-year,3-year and 5-year DFS and OS of GC patients according to their preoperative clinicopathologic characteristics and PM distance. | Jun Luo Yuming Jiang Xinhua Chen Yuehong Chen Jhang Lopsang Gurung Tingyu Mou Liying Zhao Guoqing Lyu Tuanjie Li Guoxin Li Jiang Yu | 2020 | Chinese Journal of Cancer Research2020，32，2： | 8 |
| 3 | Surgical management of gastric stump cancer:a report of 37 cases显示文摘Objective: To observe the clinicopathological characteristics of gastric stump cancer (GSC) and evaluate the benefits of radical surgery of GSC. Methods: The clinicopathological characteristics and postoperative survival time of 37 GSC patients who underwent surgery were investigated retrospectively. The survival time was compared according to the type of surgical pTMN stage. Survival curves were traced by using Kaplan-Meier methods. Results: Most GSC (32/37) was detected in patients who had received Billroth Ⅱ reconstruction after partial gastrectomy for benign gastric disease. The lesser curvature side and the suture line of anastomosis were the most frequent sites where GSC occurred (27/37). Differentiated adenocarcinoma was the dominant histopathological type (24/37). The postoperative 5-year survival rate of early stage GSC patients (n=9) was significantly higher than advanced stage GSC (n=12) (55.6% vs 16.5%, xL2=1 1.48, P<0.01). Five-year survival rate of 21 GSC patients with radical resection were 75% (3/4) for stage Ⅰ, 60% (3/5) for stage Ⅱ, 14.2% (1/7) for stage Ⅲ, and 0% (0/5) for stage Ⅳ respectively.The median survival time of 21 GSC patients who underwent radical resection was longer than those undergoing palliative operation (43.0m vs 13.0m, xL2=36.31, P<0.01), the median survival time of stage Ⅳ patients with radical resection was 23.8months. Conclusions: Without remote metastasis, radical resection for GSC is possible, and is an effective way to improve the prognosis of GSC. Even in stage Ⅳ GSC, radical resection can still prolong the survival time. It is necessary for the patients with benign gastric diseases who received partial gastrectomy to carry out the endoscopy follow-up, especially in patients with Billroth Ⅱ reconstruction procedure at 15-20 years. | 陈力 田华 陈健 何志刚 陶思丰 LOKESH Gurung 彭淑牖 | 2005 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2005，6，1： | 4 |
| 4 | Tailored PEDOT:PSS hole transport layer for higher performance in perovskite solar cells: Enhancement of electrical and optical properties with improved morphology显示文摘Precise control over the charge carrier dynamics throughout the device can result in outstanding performance of perovskite solar cells(PSCs).Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)is the most actively studied hole transport material in p-i-n structured PSCs.However,charge transport in the PEDOT:PSS is limited and inefficient because of its low conductivity with the presence of the weak ionic conductor PSS.In addition,morphology of the underlying PEDOT:PSS layer in PSCs plays a crucial role in determining the optoelectronic quality of the active perovskite absorber layer.This work is focused on realization of a non-wetting conductive surface of hole transport layer suitable for the growth of larger perovskite crystalline domains.This is accomplished by employing a facile solventengineered(ethylene glycol and methanol)approach resulting in removal of the predominant PSS in PEDOT:PSS.The consequence of acquiring larger perovskite crystalline domains was observed in the charge carrier dynamics studies,with the achievement of higher charge carrier lifetime,lower charge transport time and lower transfer impedance in the solvent-engineered PEDOT:PSS-based PSCs.Use of this solventengineered treatment for the fabrication of MAPbI3 PSCs greatly increased the device stability witnessing a power conversion efficiency of 18.18%,which corresponds to^37%improvement compared to the untreated PEDOT:PSS based devices. | Khan Mamun Reza Ashim Gurung Behzad Bahrami Sally Mabrouk Hytham Elbohy Rajesh Pathak Ke Chen Ashraful Haider Chowdhury Md Tawabur Rahman Steven Letourneau Hao-Cheng Yang Gopalan Saianand Jeffrey WElam Seth BDarling Qiquan Qiao | 2020 | Journal of Energy Chemistry2020，29，5： | 4 |
| 5 | hTERT,CEA及CMV启动子在人结肠癌细胞株中的转录活性比较显示文摘目的:比较人端粒酶催化亚单位(hTERT),癌胚抗原(CEA)及巨细胞病毒(CMV)启动子在人结肠癌细胞株LoVo和SW480中的转录活性。方法:设计引物应用PCR法从人结肠癌基因组中克隆hTERT和CEA启动子;用双酶切和PCR法切除原始载体pLVX-EGFP-3FLAG中的CMV启动子后,将hTERT,CEA启动子与该载体重组,构建出重组质粒pLVX-hTERTp-EGFP-3FLAG和pLVX-CEAp-EGFP-3FLAG;将上述两种质粒及原始载体(含CMV启动子)分别瞬时转染人结肠癌细胞株LoVo和SW480后,检测两种细胞株绿色荧光蛋白表达。结果:经PCR,酶切及测序鉴定,克隆及载体构建完全正确。CMV,hTERT及CEA启动子的转录活性(绿色荧光细胞数/总细胞数)在LoVo细胞中依次为54.7%,33.0%,9.5%;在SW480中依次为16.5%,10.1%,8.5%,差异均有统计学意义(均P<0.05)。结论:在人结肠癌细胞株中,转录活性以CMV启动子最高,hTERT启动子次之,CEA启动子最低。该结果可为结肠癌的靶向性基因治疗研究提供参考。 | 贺赛 孙学军 郑见宝 陈南征 任燕飞 Rajendra Gurung 魏光兵 张立 姚建峰 尉春艳 | 2014 | 中国普通外科杂志2014，23，1： | 4 |
| 6 | Characteristics of landslide in Koshi River Basin,Central Himalaya显示文摘Koshi River basin, which lies in the Central Himalayas with an area of 71,500 km2, is an important trans-boundary river basin shared by China, Nepal and India. Yet, landslide-prone areas are all located in China and Nepal, imposing alarming risks of widespread damages to property and loss of human life in both countries. Against this backdrop, this research, by utilizing remote sensing images and topographic maps, has identified a total number of 6877 landslides for the past 23 years and further examined their distribution, characteristics and causes. Analysis shows that the two-step topography in the Himalayan region has a considerable effect on the distribution of landslides in this area. Dense distribution of landslides falls into two regions: the Lesser Himalaya(mostly small and medium size landslides in east-west direction) and the TransitionBelt(mostly large and medium size landslides along the river in north-south direction). Landslides decrease against the elevation while the southern slopes of the Himalayas have more landslides than its northern side. Change analysis was carried out by comparing landslide distribution data of 1992, 2010 and 2015 in the Koshi River basin. The rainfallinduced landslides, usually small and shallow and occurring more frequently in regions with an elevation lower than 1000 m, are common in the south and south-east slopes due to heavy precipitation in the region, and are more prone to the slope gradient of 20°~30°. Most of them are distributed in Proterozoic stratum(Pt3ε, Pt3 and Pt2-3) and Quaternary stratum. While for earthquake-induced landslides, they are more prone to higher elevations(2000~3000 m) and steeper slopes(40°~50°). | ZHANG Jian-qiang LIU Rong-kun DENG Wei KHANAL Narendra Raj GURUNG Deo Raj MURTHY Manchiraju Sri Ramachandra | 2016 | Journal of Mountain Science2016，13，10： | 4 |
| 7 | 定性研究方法在肺结核病人发现研究中的应用显示文摘目的:运用定性研究方法找出重庆地区肺结核病人低发现率的主要影响因素,为提出有效的病人发现模式提供依据,提高病人发现率。方法:采用了问题分析和矩阵排序、个人深入访谈、专题小组讨论等多种定性研究的方法,对包括结防专业机构的医护人员、结核病现症病人等进行了采访。结果:政府财政投入不足、高危人群筛查工作开展不足、医疗费用过高、交通不便等因素是制约重庆市结核病人发现工作的主要因素,其中政府财政投入不足影响最大。结论:采用问题分析和矩阵排序的方法明确了不同的因素对病人发现的影响程度。只有更好地落实政府承诺,加强结防机构自身建设,定期开展高危人群的筛查工作及加强归口管理工作,才能够切实地提高病人发现水平。 | 陈静 汪洋 李颖 胡代玉 Lekha Gurung | 2006 | 现代预防医学2006，33，1： | 4 |
| 8 | ^137Cs tracing dynamics of soil erosion,organic carbon,and total nitrogen in terraced fields and forestland in the Middle Mountains of Nepal显示文摘The Middle Mountains is one of the regions of Nepal most vulnerable to water erosion, where fragile geology, steep topography, anomalous climatic conditions, and intensive human activity have resulted in serious soil erosion and enhanced land degradation. Based on the 137 Cs tracing method, spatial variations in soil erosion, organic carbon, and total nitrogen(TN) in terraced fields lacking field banks and forestland were determined. Soil samples were collected at approximately 5 m and 20 m intervals along terraced field series and forestland transects respectively. Mean 137 Cs inventories of the four soil cores from the reference site was estimated at 574.33 ± 126.22 Bq m-2(1 Bq(i.e., one Becquerel) is equal to 1 disintegration per second(1 dps)). For each terrace, the 137 Cs inventory generally increased fromupper to lower slope positions, accompanied by a decrease in the soil erosion rate. Along the entire terraced toposequence, 137 Cs data showed that abrupt changes in soil erosion rates could occur between the lower part of the upper terrace and the upper part of the immediate terrace within a small distance. This result indicated that tillage erosion is also a dominant erosion type in the sloping farmland of this area. At the same time, we observed a fluctuant decrease in soil erosion rates for the whole terraced toposequence as well as a net deposition at the toe terrace. Although steep terraces(lacking banks and hedgerows) to some extent could act to limit soil sediment accumulation in catchments, soil erosion in the terraced field was determined to be serious. For forestland, with the exception of serious soil erosion that had taken place at the top of slopes due to concentrated flows from a country road situated above the forestland site, spatialvariation in soil erosion was similar to the 'standard' water erosion model. Soil organic carbon(SOC) and TN inventories showed similar spatial patterns to the 137 Cs inventory for both toposequences investigated. However, due to the different dominant erosion processes between the two, we found similar patterns between the <0.002 mm soil particle size fraction(clay sized) and 137 Cs inventories in terraced fields, while different patterns could be found between 137 Cs inventories and the <0.002 mm soil particle size fraction in the forestland site. Such results confirm that 137 Cs can successfully trace soil erosion, SOC and soil nitrogen dynamics in steep terraced fields and forestland in the Middle Mountains of Nepal. | SU Zheng-an XIONG Dong-hong DENG Wei DONG Yi-fan MA Jing PADMA C Poudel GURUNG B Sher | 2016 | Journal of Mountain Science2016，13，10： | 4 |
| 9 | Evaluation of electricity generation from ultrasonic and heat/alkaline pretreatment of different sludge types using microbial fuel cells显示文摘 | Sang-Eun Oh Joung Yee Yoon Anup Gurung Dong-Jin Kim | 2014 | Bioresource Technology2014，，： | 2 |
| 10 | Current systematic reviews and meta-analyses of COVID-19显示文摘BACKGROUND Coronavirus disease 2019(COVID-19)has left a significant impact on the world's health,economic and political systems;as of November 20,2020,more than 57 million people have been infected worldwide,with over 1.3 million deaths.While the global spotlight is currently focused on combating this pandemic through means ranging from finding a treatment among existing therapeutic agents to inventing a vaccine that can aid in halting the further loss of life.AIM To collect all systematic reviews and meta-analyses published related to COVID-19 to better identify available evidence,highlight gaps in knowledge,and elucidate further meta-analyses and umbrella reviews that are yet to be performed.METHODS We explored studies based on systematic reviews and meta-analyses with the keyterms,including severe acute respiratory syndrome(SARS),SARS virus,coronavirus disease,COVID-19,and SARS coronavirus-2.The included studies were extracted from Embase,Medline,and Cochrane databases.The publication timeframe of included studies ranged between January 01,2020,to October 30,2020.Studies that were published in languages other than English were not considered for this systematic review.The finalized full-text articles are freely accessible in the public domain.RESULTS Searching Embase,Medline,and Cochrane databases resulted in 1906,669,and 19 results,respectively,that comprised 2594 studies.515 duplicates were subsequently removed,leaving 2079 studies.The inclusion criteria were systematic reviews or meta-analyses.860 results were excluded for being a review article,scope review,rapid review,panel review,or guideline that produced a total of 1219 studies.After screening articles were categorized,the included articles were put into main groups of clinical presentation,epi-demiology,screening and diagnosis,severity assessment,special populations,and treatment.Subsequently,there was a second subclassification into the following groups:gastrointestinal,cardiovascular,neurological,stroke,thrombosis,anosmia and dysgeusia,ocular manifestations,nephrology,cutaneous manifestations,D-dimer,lymphocyte,anticoagulation,antivirals,convalescent plasma,immunosuppressants,corticosteroids,hydroxychloroquine,renin-angiotensin-aldosterone system,technology,diabetes mellitus,obesity,pregnancy,children,mental health,smoking,cancer,and transplant.CONCLUSION Among the included articles,it is clear that further research is needed regarding treatment options and vaccines.With more studies,data will be less heterogeneous,and statistical analysis can be better applied to provide more robust clinical evidence.This study was not designed to give recommendations regarding the management of COVID-19. | Mahmoud Nassar Nso Nso Mostafa Alfishawy Anastasia Novikov Salim Yaghi Luis Medina Bahtiyar Toz Sofia Lakhdar Zarwa Idrees Yungmin Kim Dawa Ongyal Gurung Raheel S Siddiqui David Zheng Mariam Agladze Vikram Sumbly Jasmine Sandhu Francisco Cuevas Castillo Nadya Chowdhury Ravali Kondaveeti Sakil Bhuiyan Laura Guzman Perez Riki Ranat Carlos Gonzalez Harangad Bhangoo John Williams Alaa Eldin Osman Joyce Kong Jonathan Ariyaratnam Mahmoud Mohamed Ismail Omran Mariely Lopez Akwe Nyabera Ian Landry Saba Iqbal Anoosh Zafar Gondal Sameen Hassan Ahmed Daoud Bahaaeldin Baraka Theo Trandafirescu Vincent Rizzo | 2021 | World Journal of Virology2021，10，4： | 2 |
| 11 | 肝特异性对比剂对肝功能解剖分布的初步探讨显示文摘目的 利用肝特异性对比剂探讨肝功能的解剖分布规律。方法分析2012年7月-2014年6月期间行肝脏EOB-CE-MRI的47例患者影像学及临床资料,按照Child-Pugh分级(CPS)分为:正常组19例,CPS A级组15例,CPS B级组13例。采用肝脏相对强化率(LLRE)的方法进行测量,比较三组肝中央区与周围区、左叶与右叶、右前段与右后段、S2段与S3段EOBCE-MRI平扫、肝细胞期肝实质信号以及肝细胞期肝实质相对强化率的差异。结果运用LLRE方法三组患者肝中央区与周围区间差异有统计学意义(P〈0.001),左叶与右叶间、右前段与右后段、S2段与S3段不存在统计学差异(P〉0.05)。全肝平均信号均值平扫各组间无差异,增强之后各组间存在显著性差异,P值均小于0.05。结论 肝中央区肝功能储备高于周围区,左右叶及S2、S3段之间肝功能差异不明显,全肝平均相对强化率各组之间显著不同。 | 刘珏 Mahendru Gurung 朱望舒 李勇 | 2015 | 岭南现代临床外科2015，15，5： | 2 |
| 12 | Ecotourism in Bhutan显示文摘 | Dhan B. Gurung Klaus Seeland | 2008 | Annals of Tourism Research2008，，2： | 2 |
| 13 | Automated detection of lung nodules in multidetector CT:influence of different reconstruction protocols on performance of a software prototype显示文摘 | GURUNG J MAATAOUI A KHAN M | 2006 | Rofo2006，178，1： | 1 |
| 14 | 1-D analytical solution for extensible and inextensible soil/rock reinforcement in pull-out tests显示文摘 | GURUNG N | 2001 | Geotextiles and Geomembranes2001，19，： | 1 |
| 15 | Factors Determining Intercropping by Rubber Smallholders in Sri Lanka:a Logit Analysis显示文摘 | Sankhayan P L Gurung N Sitaula B K | 2003 | Agriculture Ecosystems & Environment2003，94，1： | 1 |
| 16 | The effects of distillers dried grains with solubles on feed intake, growth performance, gain efficiency and carcass quality of growing Kiko x Spanish male goats 显示文摘 | GURUNG N K SOLA1MAN S G RANKINS D L | 2009 | Journal of Animal and Veterinary Advances2009，8，10： | 1 |
| 17 | Characterization of Plasmids encoding CTX-M β-lactamase and their Addiction Systems in Escherichia coli isolates from Animals显示文摘 | Migma Dorji Tamang Mamata Gurung Min-Su Kang Hyang-Mi Nam Dong Chan Moon Geum-Chan Jang Suk-Chan Jung Yong Ho Park Suk-Kyung Lim | 2014 | Veterinary Microbiology2014，，： | 1 |
| 18 | Enzymatic synthesis of apigenin glucosides by glucosyltransferase (YjiC) from Bacillus licheniformis DSM 13显示文摘 | Rit Bahadur Gurung Eun-Hee Kim Tae-Jin Oh Jae Kyung Sohng | 2013 | Molecules and Cells2013，，4： | 1 |
| 19 | Increased angio- genic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance al- ters trophoblast funetion显示文摘 | Wallace AE Fraser R Gurung S | 2014 | Hum Reprod2014，29，4： | 1 |
| 20 | Feeding per- formance and blood parameters of male goat kids fed EasiFlo cottonseed显示文摘 | Solaiman SG Gurung NK McCrary Q | 2009 | Small Ruminant Research2009，81，2： | 1 |
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