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26篇 您的检索式:作者名="Gushima"
    题名 作者 年代 出处 被引量
1A white opaque substance-positive gastric hyperplastic polyp with dysplasia显示文摘The endoscopic findings of gastric hyperplastic polyps (HPs) with dysplasia have not been well-defined, and the clinical significance of these lesions, including their malignant potential, is unclear. In this report, we describe a case of a white opaque substance (WOS)positive gastric HP with dysplasia. A 76-year-old woman was referred to our hospital for endoscopic resection of a gastric HP. Upper endoscopy revealed a 25-mm whitish and reddish polypoid lesion on the greater curvature in the lower third of the stomach. The whitish part was diagnosed as a WOS using conventional and magnifying endoscopy with narrow band imaging. An examination of the biopsy specimen indicated that the lesion was a typical gastric HP. However, because of its color and the presence of a WOS, we suspected that this lesion was an atypical gastric HP. Therefore, we performed a polypectomy. Histopathologically, diffuse lowto high-grade dysplasia was found on the surface of the polyp. We performed immunohistochemical staining using a monoclonal antibody specific for adipophilin as a marker of lipid droplets (LDs). LDs were detected in approximately all of the neoplastic cells, especially in the surface epithelium of the intervening apical parts and were located in the subnuclear cytoplasm of the neoplastic cells. According to endoscopic and histopathological findings, the WOS-positive epithelium indicated dysplasia of the gastrointestinal phenotype, which could absorb lipids. The presence of a WOS in a gastric HP may be considered an endoscopic finding that is predictive of the neoplastic transformation of a gastric HP. We suggest that a WOS-positive gastric HP should be resected endoscopically to investigate its neoplastic transformation.Hiroya Ueyama Kenshi Matsumoto Akihito Nagahara Ryosuke Gushima Takuo Hayashi Takashi Yao Sumio Watanabe 2013World Journal of Gastroenterology2013,19,26:4
2Construction of Glutathione-Producing Strains of Escherichia coli B by Recombinant DNATechniques 显示文摘GUSHIMA H MIYA T 1983Journal of applied biochemistry1983,5,:1
3Expression of matrix metalloproteinasesin pigs with hyperoxia-induced acute lung injury显示文摘Gushima Y Ichikado K Suga M 2001Eur Respir J2001,18,5:1
4Expression of matrix metalloproteinases in pigs with hyperoxia-induced acute oung injury显示文摘 ichikado K Suga M 2001Eur Respir J2001,18,5:1
5Expression of matrix metalloproteinasesin pigs with hyperoxia-induced acute lung injury显示文摘Gushima Y Ichikado K Suga M 2001Eur Respir J2001,18,5:1
6Constructionof glutathione-producing strains of Escherichia coli B by recombinant DNA techniques显示文摘GUSHIMA H MIYA T MURATA K 1983J Appl Biochem1983,5,:1
7Application of adhesion improvement material jetting to prevent wheel skidding and slipping(in Japanease)显示文摘Ohno K Ban T Gushima K Ohe S.Honda K 0,,04:1
8Measurement of Mass Flow Rate of Particles in GasSolid Suspension Flowing in Pipe显示文摘Gushima K Sakamoto H Ohno K Tokita M. Saito K.and Masuda H 0,,10:1
9Measurement of Particle Flow-rate by Monitoring Static Electricity under Varied Vibration Condisions显示文摘Gushima K Tomioka T Sakamoto H Ohno K. Tokita M.Masuda H 0,,08:1
10Purification and characterization of glutathione synthetase from Escherichia coli B显示文摘 T Miya K Murata 1983J Appl Biochem1983,5,:1
11Cloning and amplification of a gene for glutathione synthetase in Escherichia coli B显示文摘 T Miya H Gushima 1983Agric Biol Chem1983,47,:1
12Mucin core protein expression in serrated polyps of the large intestine显示文摘Kohei Fujita Minako Hirahashi Hidetaka Yamamoto Takayuki Matsumoto Masaki Gushima Yoshinao Oda Junji Kishimoto Takashi Yao Mitsuo Iida Masazumi Tsuneyoshi 2010Virchows Archiv2010,,4:1
13Construction of glutathione-producing strains of Escherichia coli B by recombinant DNA techniques显示文摘 T Miya K Murata 1983J Appl Biochem1983,5,:1
14Expression of matrix metalloproteinase in pigs with hyperoxia-induced acute lung injury显示文摘Gushima Y Ichikado K Suga M 2001Eur Respir J2001,18,5:1
15Fibroproliferative changes on high-resolution CT in the acute respiratory distress syndrome predict mortality and ventilator dependency: a prospective observational cohort study 显示文摘Ichikado K Muranaka H Gushima Y 2012BMJ Open2012,2,00:1
16A case of severe acutepancreatitis with hyperlipidemia in a pregnant woman显示文摘Ido Y Gushima R Ozaki T 2012NihonShokakibyo Gakkai Zasshi2012,109,7:1
17Construction of glutathione-producing strains of Escherichia coli B by recombinant DNA techniques显示文摘Gushima H Miya T Murata K 1983J Appl Biochem1983,5,:1
18Construction of glutathione-producing strains of Escherichia coli B by recombinant DNA techniques 显示文摘Gushima H Miya T Maratoa K 1983J Appl Biochem1983,5,12:1
19Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection显示文摘Fuller MJ Shoukry NH Gushima T 2010Hepatology2010,51,2:1
20Expression of matrix metalloproteinases in pigs with hyperoxia induced acute lung injury显示文摘Gushima Y Ichikado K Suga M 2001Eur Respir J2001,18,5:1
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