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6篇 您的检索式:作者名="Haijun Zhuang"
    题名 作者 年代 出处 被引量
1Comparative analysis of upper ureteral stones (>15 mm) treated with retroperitoneoscopic ureterolithotomy and ureteroscopic pneumatic lithotripsy显示文摘YunYan Wang JianQuan Hou DuanGai Wen Jun OuYang JunSong Meng HaiJun Zhuang 2010International Urology and Nephrology2010,,:2
2Therapeutic potential of C1632 by inhibition of SARS-CoV-2 replication and viral-induced inflammation through upregulating let-7显示文摘Dear Editor,The COVID-19 pandemic caused by SARS-CoV-2 has led to acute respiratory distress syndrome(ARDS)with a high rate of death.An excessive inflammatory response,caused by virus infection,is associated with severe clinical manifestations that may lead to death of patients.1 Therefore,the blockage of virus replication and suppression of hyper-inflammatory response are beneficial for COVID-19 treatment.However,the drug targeting both virus and hyper-inflammation,as far as we know,is not available yet.Chen Xie Yanlian Chen Dongling Luo Zhen Zhuang Heping Jin Haoxian Zhou Xiaocui Li Haijun Lin Xiaohui Zheng Jing Zhang Peihui Wang Jincun Zhao Yong Zhao Hui Huang 2021Signal Transduction and Targeted Therapy2021,6,3:1
3Global urbanization research from 1991 to 2009: A systematic research review显示文摘Haijun Wang Qingqing He Xingjian Liu Yanhua Zhuang Song Hong 2011Landscape and Urban Planning2011,,3:1
4Global urbanization research from 1991 to 2009: A systematic research review显示文摘Haijun Wang Qingqing He Xingjian Liu Yanhua Zhuang Song Hong 2011Landscape and Urban Planning2011,,3:1
5膀胱癌组织中MMP-2与TIMP-2 mRNA的表达及临床意义(英文)显示文摘Objective:The aim of the study was to investigate the expressions of matrix metalloproteinase-2(MMP-2) and tissue inhibitor of MMP-2(TIMP-2) mRNA in transitional cell carcinomas of bladder and discuss their clinical significances.Methods:Using RT-PCR and real time quantitative PCR(RQ-PCR) technique,the expressions of MMP-2 and TIMP-2 mRNA of 45 cases of bladder carcinoma(tumor group) and 10 cases of normal bladder tissue(control group) were analyzed.Results:MMP-2 and TIMP-2 were not expressed in control group.MMP-2 was expressed in 30 cases tumor samples and TIMP-2 was expressed in 26 cases.The expression of MMP-2 mRNA in non-muscle invasive bladder cancers and grade I cancers was lower than that in muscle invasive bladder cancers and grades II-III cancers respectively.The differences were statistically significant(P<0.05).The expression of MMP-2 in recurrent patients was higher than that in incipient patients.TIMP-2 mRNA expression decreased with grades and stage.The expression of TIMP-2 in non-muscle invasive bladder cancers and grade I cancers was higher than that in muscle invasive bladder cancers and grades II-III cancers respectively.There was statistical difference between two groups(P < 0.05).TIMP-2 expression in incipient patients was higher than that in recurrent patients,but the difference was not significant(P>0.05).Conclusion:These results suggest that MMP-2 and TIMP-2 play an important role in the invasion step of transitional cell carcinoma of bladder.MMP-2 may become a new approach to the diagnosis of bladder carcinoma.Yunyan Wang Junsong Meng Haijun Zhuang Jianquan Hou Duangai Wen 2011The Chinese-German Journal of Clinical Oncology2011,10,5:0
6Immune checkpoint inhibitors-associated cardiotoxicity in immunotherapy trials on gastrointestinal cancer patients显示文摘To the editor:Gastrointestinal(GI)cancer is the most common malignancy in China.[1]For many decades,the treatment options for GI cancers have been limited to surgery,radiotherapy,and chemotherapy.Over recent years,immune checkpoint inhibitors(ICIs)that target programmed cell death 1(PD-1),or its programmed death-ligand 1(PD-L1),have demonstrated promising efficacies and changed the treatment landscape in GI cancer.[2]However,immune-related adverse events(irAEs)can occur during ICI treatment.Furthermore,ICI-associared cardiotoxicity is a rare but potentially fatal toxic effect.Li Yiqun Wang Yanfeng Li Ning Liang Xinjun Zhang Shu Fan Qingxia Yin Xianli Zhuang Zhixiang Liu Yunpeng Zhang Jingdong Kou Xiaoge Zhong Haijun Xu Binghe Huang Jing 2022Chinese Medical Journal2022,,8:0
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