|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Immunogenetic characteristics of patients with autoimmune gastritis显示文摘AIM:To explore whether predisposition to autoimmune gastritis (AIG) is found in human leukocyte antigen (HLA), cytokine or killer cell immunoglobulin-like receptor (KIR) gene variations.METHODS: Twelve Finnish patients with autoimmunetype severe atrophy of the gastric corpus were included. The patients' serum was analyzed for pepsinogen-interleukin (IL)-1 gene cluster, IL-2, IL-4, IL-6, IL-10, IL-12, interferon γ, transforming growth factor β, and tumor necrosis factor α. Variation in KIR genes was also explored. The results were compared with prevalence of the polymorphisms in Finnish or European populations.RESULTS: All patients had pepsinogen-CONCLUSION: As explored with modern DNA-based methods, HLA-DRB1*04 and DQB1*03 alleles, but not HLA-B8-DRB1*03, may predispose to AIG. | Aino Mirjam Oksanen Katri Eerika Haimila Hilpi Iris Kaarina Rautelin Jukka Antero Partanen | 2010 | World Journal of Gastroenterology2010，16，3： | 8 |
| 2 | Genetic polymorphism of the human ICOS gene 显示文摘 | Haimila KE Partanen JA Holopainen PM | 2002 | Immunogenetics2002，53，12： | 1 |
| 3 | Geographic distribution of cervical cancer-associated human leucocyte antigens and cervical cancer incidence in Finland显示文摘 | Castro FA Haimila K Pasanen K | 2007 | Int J STD AIDS2007，18，10： | 1 |
| 4 | KM in practice:Tile helping hand of BI显示文摘 | Haimila S | 2001 | Knowledge Management Wor!d2001，10，10： | 1 |
| 5 | Association of HLA-DRB1,interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population-a candidate gene approach显示文摘 | Castro FA Haimila K Sareneva I | 2009 | Int J Cancer2009，125，8： | 1 |
| 6 | Genetic polymorphismof the human ICOS gene显示文摘 | Haimila KE Partanen JA Holopainen PM | 2002 | Immunogenetics2002，53，12： | 1 |
| 7 | KM in practice: The helping hand of BI显示文摘 | Haimila S | 2001 | Knowledge Management World2001，10，10： | 1 |
| 8 | Degree of Damage to the Small Bowel and Serum Antibody Titers Correlate With Clinical Presentation of Patients With Celiac Disease显示文摘 | Juha Taavela Kalle Kurppa Pekka Collin Marja–Leena L?hdeaho Teea Salmi P?ivi Saavalainen Katri Haimila Heini Huhtala Kaija Laurila Harri Siev?nen Markku M?ki Katri Kaukinen | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 1 |
| 9 | Gluten-dependent Small Bowel Mucosal Transglutaminase 2–specific IgA Deposits in Overt and Mild Enteropathy Coeliac Disease显示文摘 | Outi Koskinen Pekka Collin Ilma Korponay-Szabo Teea Salmi Sari Iltanen Katri Haimila Jukka Partanen Markku M?ki Katri Kaukinen | 2008 | Journal of Pediatric Gastroenterology and Nutrition2008，，4： | 1 |
| 10 | Association of HLA- DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population-a candidate gene approach 显示文摘 | Castro FA Haimila K Sareneva I | 2009 | Int J Cancer2009，125，8： | 1 |
| 11 | Genetic polymorphism of the human ICOS gene 显示文摘 | Haimila K E Partanen J A Holopainen P M | 2002 | Immunogenetics2002，53，： | 1 |
| 12 | Geographic distribution of cervical cancer-ussociated human leucocyte antigens and cervical cancer incidence in Finland显示文摘 | Haimila K Pusanen K | 2007 | Int J STD AIDS2007，18，10： | 1 |
| 13 | Association of HLA-DRB1,interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population:a candidate gene approach显示文摘 | Castro FA Haimila K Sareneva I | | 0，，8： | 1 |
| 14 | Genetic polymorphism of the human ICOS gene显示文摘 | Haimila K E Partanen J A Holopainen P M | 2002 | Immunogeneics2002，53，： | 1 |
| 15 | Genetic association of celiac disease susceptibility to polymorphisms in the ICOS gene on chromosome 2q33 显示文摘 | Haimila K Smedberg T Mustalahti K | 2004 | Genes Immun2004，5，： | 1 |
| 16 | Genetic polymorphism of the human ICOS gene 显示文摘 | Haimila KE Partanen JA Holopainen PM | 2002 | Immunogenetics2002，53，： | 1 |
| 17 | Cost-effective HLA typing with tagging SNPs predicts celiac disease risk haplotypes in the Finnish, Hungarian, and Italian populations显示文摘 | Lotta Koskinen Jihane Romanos Katri Kaukinen Kirsi Mustalahti Ilma Korponay-Szabo Donatella Barisani Maria Teresa Bardella Fabiana Ziberna Serena Vatta Gy?rgy Széles Zsuzsa Pocsai Kati Karell Katri Haimila Róza ádány Tarcisio Not Alessandro Ventura Markku | 2009 | Immunogenetics2009，，4： | 1 |
| 18 | Endomysial antibodies predict celiac disease irrespective of the titers or clinical presentation显示文摘AIM:To investigate the association between serum antibody levels and a subsequent celiac disease diag-nosis in a large series of children and adults. METHODS:Besides subjects with classical gastrointestinal presentation of celiac disease,the study cohort included a substantial number of individuals with extraintestinal symptoms and those found by screening in at-risk groups.Altogether 405 patients underwent clinical,serological and histological evaluations.After collection of data,the antibody values were further graded as low[endomysial(EmA)1:5-200,transglutaminase 2 antibodies(TG2-ab)5.0-30.0 U/L]and high (EmA 1:≥500,TG2-ab≥30.0 U/L),and the serological results were compared with the small intestinal mucosal histology and clinical presentation. RESULTS:In total,79%of the subjects with low and 94%of those with high serum EmA titers showed small-bowel mucosal villous atrophy.Furthermore, 96%of the 47 EmA positive subjects who had normal mucosal villi and remained on follow-up either subsequently developed mucosal atrophy while on a glutencontaining diet,or responded positively to a glutenfree diet. CONCLUSION:Irrespective of the initial serum titers or clinical presentation,EmA positivity as such is a very strong predictor of a subsequent celiac disease diagnosis. | Kalle Kurppa Tiia Rsnen Pekka Collin Sari Iltanen Heini Huhtala Merja Ashorn Pivi Saavalainen Katri Haimila Jukka Partanen Markku Mki Katri Kaukinen | 2012 | World Journal of Gastroenterology2012，18，20： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员