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| 1 | Drainage vs. non-drainage after cholecystectomy for acute cholecystitis:a retrospective study显示文摘Many surgeons practice prophylactic drainage after cholecystectomy without reliable evidence,this study was conducted to answer the question whether to drain or not to drain after cholecystectomy for acute calculous cholecystitis.A retrospective review of all patients who had cholecystectomy for acute cholecystitis in Aseer Central Hospital,Abha,Saudi Arabia,was conducted from April 2010 to April 2012.Data were extracted from hospital case files.Preoperative data included clinical presentation,routine investigations and liver function tests.Operative data included excessive adhesions,bleeding,bile leak,and drain insertion.Complicated cases such as pericholecystic collections,mucocele and empyema were also reported.Patients who needed therapeutic drainage were excluded.Postoperative data included hospital stay,volume of drained fluid,time of drain removal,and drain site problems.The study included 103 patients allocated into two groups;group A(n = 38) for patients with operative drain insertion and group B(n = 65) for patients without drain insertion.The number of patients with preoperative diagnosis of acute non-complicated cholecystitis was significantly greater in group B(80%) than group A(36.8%)(P < 0.001).Operative time was significantly longer in group A.All patients who were converted from laparoscopic to open cholecystectomy were in group A.Multivariate analysis revealed that hospital stay was significantly(P < 0.001) longer in patients with preoperative complications.There was no added benefit for prophylactic drain insertion after cholecystectomy for acute calculous cholecystitis in non-complicated or in complicated cases. | Mohammed A Bawahab Walid M Abd El Maksoud Saeed A Alsareii Fahad S Al Amri Hala F Ali Abdul Rahman Nimeri Abdul Rahman M Al Amri Adel A Assiri Mohammed I Abdul Aziz | 2014 | The Journal of Biomedical Research2014，28，3： | 3 |
| 2 | A basic algebra is an MV-atgebra if and only if it is a BCC-algebra 显示文摘 | Chajda I Halas R | 2008 | International Journal of Theo retical Physics2008，47，： | 1 |
| 3 | Co-pyrolysis of polymenthyl methacrylates with brown coal and effect on monomer production 显示文摘 | Orinak A Halas L Amar I | 2006 | Fuel2006，，85： | 1 |
| 4 | Effect of different levels of mannan-oligosaccharide supplementation on some immunological variables in weaned piglets显示文摘 | Noehta I Tuboly T Halas V | 2009 | J Anim Physiol Anim Nutr2009，93，： | 1 |
| 5 | Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control显示文摘 | Eman A El-ghoroury Hala M Raslan Ehsan A Badawy Gamila S El-Saaid Mervat H Agybi Ibrahem Siam Sohair I Salem | 2009 | Blood Coagulation & Fibrinolysis2009，，4： | 1 |
| 6 | Semimicrodetermination ofvapor-liquid equilibrium显示文摘 | Wichterle I Hala E | 1963 | Ind Eng Chem Fundam1963，2，2： | 1 |
| 7 | Clinical significance of asymptomatic urogenital Mycoplasma hominisand Ureaplasma urealyticumin relation to seminal fluid parameters among infertile Jordanian males显示文摘 | Hala I A1-Daghistani Muna Abdel-Dayem | 2010 | Middle East Fertility Soc J2010，15，： | 1 |
| 8 | Mannan oligosaccharides in nursery pig nutrition and their potential mode of ac- tion显示文摘 | Halas V Nochta I | 2012 | Animals2012，2，2： | 1 |
| 9 | On the role of logical connec- tives for primality and functional completeness of algebras of logics显示文摘 | Chajda I Halas R Rosenberg I G | 2010 | Information Sciences2010，180，8： | 1 |
| 10 | Effects of earthworm casts and compost on soil microbial activity and plant nutrient availability 显示文摘 | Hala I Chaoui | 2003 | Soil Biology & Biochemistry2003，，29： | 1 |
| 11 | Constituents of Nelumbo nucifera leaves and their antimalarial and antifungal activityp显示文摘 | Vijai K Agnihotri Hala N ElSohly Shabana I Khan | 2008 | Phytochemistry letters2008，1，： | 1 |
| 12 | Clinical significance of asymptomatic urogenital Mycoplasma hominis and ureaplasma urealyticum in relation to seminal fluid parameters among infertile Jordanian males显示文摘 | Hala I Daghistani A Dayem MA | 2010 | Middle East Fertil Soc J2010，15，1： | 1 |
| 13 | The Fano resonance in plasmonic nanostructures and metamaterials 显示文摘 | LUK'YANCHUK B ZHELUDEV N I MAIER S A HALAS N J NORDLANDER P GIESSEN H CHONG C T | 2010 | Nature Materials2010，9，： | 1 |
| 14 | Effects of earth- worm casts and compost on soil microbial activity and plant nutrient availability显示文摘 | Hala I C Larry M Z Tsutomu O | 2003 | Soil Biology and Bio- chemistry2003，35，： | 1 |
| 15 | Effects of earthworm castsand compost on soil microbial activity and plant nutrient availa-bility显示文摘 | Hala I C Larry M Z Tsutomu O | 2003 | Soil Biology and Biochemistry2003，35，2： | 1 |
| 16 | Effects of earthworm casts and compost on soil microbial activity and plant nutrient availability显示文摘 | Hala I Chaoui Larry M Zibilske | 2003 | Soil Biology and Biochemistry2003，2，35： | 1 |
| 17 | The role for the exocyst complex subunits Exo70B2 and Exo70H1 in the plant- pathogene interaction显示文摘 | PECENKOVA T HALA M KULICH I | 2011 | Journal of Experimental Botany2011，62，6： | 1 |
| 18 | Mannan Oligosaccharides in Nursery Pig Nutrition and Their Potential Mode of Action显示文摘 | Halas V Nochta I | 2012 | Animals2012，2，： | 1 |
| 19 | Co-pyrolysis of polym- ethyl methacrylate with brown coal and effect on monomer production显示文摘 | Orinak A Halas L Amar I | 2006 | Fuel2006，85，1： | 1 |
| 20 | Impact of direct-acting antiviral regimens on hepatic and extrahepatic manifestations of hepatitis C virus infection显示文摘Hepatitis C virus(HCV)is a common cause of liver disease and is associated with various extrahepatic manifestations(EHMs).This mini-review outlines the currently available treatments for HCV infection and their prognostic effect on hepatic manifestations and EHMs.Direct-acting antiviral(DAA)regimens are considered pan-genotypic as they achieve a sustained virological response(SVR)>85%after 12 wk through all the major HCV genotypes,with high percentages of SVR even in advanced fibrosis and cirrhosis.The risk factors for DAA failure include old males,cirrhosis,and the presence of resistance-associated substitutions(RAS)in the region targeted by the received DAAs.The effectiveness of DAA regimens is reduced in HCV genotype 3 with baseline RAS like A30K,Y93H,and P53del.Moreover,the European Association for the Study of the Liver recommended the identification of baseline RAS for HCV genotype 1a.The higher rate of hepatocellular carcinoma(HCC)after DAA therapy may be related to the fact that DAA regimens are offered to patients with advanced liver fibrosis and cirrhosis,where interferon was contraindicated to those patients.The change in the growth of pre-existing subclinical,undetectable HCC upon DAA treatment might be also a cause.Furthermore,after DAA therapy,the T cell-dependent immune response is much weaker upon HCV clearance,and the down-regulation of TNF-αor the elevated neutrophil to lymphocyte ratio might increase the risk of HCC.DAAs can result in reactivation of hepatitis B virus(HBV)in HCV coinfected patients.DAAs are effective in treating HCV-associated mixed cryoglobulinemia,with clinical and immunological responses,and have rapid and high effectiveness in thrombocytopenia.DAAs improve insulin resistance in 90%of patients,increase glomerular filtration rate,and decrease proteinuria,hematuria and articular manifestations.HCV clearance by DAAs allows a significant improvement in atherosclerosis and metabolic and immunological conditions,with a reduction of major cardiovascular events.They also improve physical function,fatigue,cognitive impairment,and quality of life.Early therapeutic approach with DAAs is recommended as it cure many of the EHMs that are still in a reversible stage and can prevent others that can develop due to delayed treatment. | Iman Ibrahim Salama Hala M Raslan Ghada A Abdel-Latif Somaia I Salama Samia M Sami Fatma A Shaaban Aida M Abdelmohsen Walaa A Fouad | 2022 | World Journal of Hepatology2022，14，6： | 0 |
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