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| 1 | Ultra-high sensitivity of rhodamine B sensing based on NaGdF_4:Yb^(3+),Er^(3+)@NaGdF_4 core-shell upconversion nanoparticles显示文摘A series of mono-dispersed hexagon NaGdF_4:Yb^(3+),Er^(3+)@NaGdF_4 core-shell nanoparticles with different shell thickness were synthesized via a co-precipitation method. Nanoparticles with high upconversion fluorescent emissions result in large signal-to-noise ratio, which guarantees the accuracy of the sensitivity. Besides, the maximum sensitivity of these NPs as detection film increases first and then decreases with the shell thickness increasing. When the shell thickness is 2.3 nm(NaGdF_4-2), the maximum sensitivity(0.69959 ppm^(-1)) is reached. A large degree of overlap between the rhodamine B absorption band and the Er^(3+) green emission bands ensures that the NaGdF_4:Yb^(3+),Er^(3+)@NaGdF_4 nanoparticles can be used as fluorescent probe to detect the concentration of rhodamine B based on fluorescent intensity ratio technology. The linear relationship between the rhodamine B concentration and the intensity ratio(R) of green and red emission intensity(I_(S+H) and I_F) were studied systematically. The result shows that the maximum sensitivity can be obtained in low concentration rhodamine B(<4 ppm), which is lower than the reported minimum detection concentration. Thus, the ultra-high sensitivity detection by NaGdF_4:Yb^(3+),Er^(3+)@NaGdF_4 core-shell upconversion nanoparticles in low concentration can be realized,which provides promising applications in bio-detection filed. | Hanping Xiong Qiuhong Min Hongqing Ma Lei Zhao Wenbo Chen Jianbei Qiu Xue Yu Xuhui Xu | 2019 | Journal of Rare Earths2019，37，4： | 2 |
| 2 | Separation-enrichment method for airborne disease spores based on microfluidic chip显示文摘Airborne diseases are likely to cause crop yield reduction,which has aroused widespread concern.In this study,a two-stage separation-enrichment structure microfluidic chip with a compound field for separation and enrichment of the greenhouse crops airborne disease spores directly from gas flow was developed.The chip is mainly composed of three parts:arc structure pretreatment channel,semicircular electrode structure and collection tank.COMSOL 5.1 software was used to simulate the designed microfluidic chip.30μm particles were used to represent P.xanthii spores,25μm particles were used to represent P.cubensis spores,and 16μm particles were used to represent B.cinerea spores.The simulation results showed that the separation and enrichment efficiency of 16μm particles,25μm particles,and 30μm particles was 88%,91%,and 94%,respectively.The experimental verification results were observed under a microscope.The results showed that the separation and enrichment efficiency of B.cinereal spores,P.cubensis spores and P.xanthii spores was 75.7%,83.8%and 89.4%,respectively.As a result,the designed microfluidic chip can be used to separate and enrich the spores of airborne diseases of greenhouse crops,which can provide a basis for the research of real-time monitoring technology for greenhouse airborne diseases. | Yafei Wang Xiaodong Zhang Ning Yang Guoxin Ma Xiaoxue Du Hanping Mao | 2021 | International Journal of Agricultural and Biological Engineering2021，14，5： | 1 |
| 3 | Significance of hypoxia-inducible factor?1α expression with atrial fibrosisin rats induced with isoproterenol显示文摘 | Fangju Su Weize Zhang Yongqing Chen Ling Ma Hanping Zhang Fei Wang | 2014 | Experimental and Therapeutic Medicine2014，，6： | 1 |
| 4 | Treatment of More Than Moderate Ischemic Mitral Regurgitation in Patients Undergoing Left Ventricular Reconstruction显示文摘Objective:While evidence-based clinical guidelines recommend chordal-sparing mitral valve replacement,rather than mitral valve repair,in patients with severe ischemic mitral regurgitation(IMR)undergoing coronary artery bypass grafting,there are no similar recommendations for patients undergoing left ventricular reconstruction(LVR).This study aimed to compare the clinical outcomes of mitral valve repair and replacement in patients undergoing LVR complicated by more than moderate IMR.Methods:In this single-center cohort study,a total of 74 consecutive patients who underwent LVR and mitral valve surgery(repair group:59;replacement group:15),during the period from March 2000 to March 2021 at Fuwai Hospital(Beijing,China)were retrospectively enrolled.Survival rates were calculated with the Kaplan-Meier method and compared using the log-rank test.Univariate Cox analysis was performed to evaluate possible confounders,followed by adjustment in multivariate analysis.The primary outcome was survival free of major adverse cardiovascular and cerebrovascular events(MACCE).Results:Median follow-up time was 59.4 months.Compared with mitral valve replacement,mitral valve repair was associated with increased risk of perioperative use of ventricular assist device(22.0%vs.0,P=0.045).There was no difference in overall survival(hazard ratio(HR),1.10;95%confidence interval(CI),0.31-3.93;Plogrank=0.888)and MACCE-free survival(HR,1.54;95%CI,0.65-3.65;Plogrank=0.319),even after multivariate Cox regression(HR,1.35;95%CI,0.37-4.88;PCox=0.646;and HR,1.41;95%CI,0.57-3.44;PCox=0.455,respectively).Furthermore,while no differences were observed in ejection fraction and left ventricular end-diastolic diameter on follow-up echocardiography,mitral valve repair was associated with an increased risk of recurrent mitral regurgitation(P=0.041).Conclusions:In patients undergoing LVR complicated by more than moderate IMR,both concomitant mitral valve repair and replacement can be successfully achieved with comparable overall and MACCE-free survival outcomes;however,mitral valve replacement may be superior to mitral valve repair for persistent correction of mitral dysfunction. | Xieraili Tiemuerniyazi Yangwu Song Hanping Ma Fei Xu Wei Zhao | 2023 | Cardiology Discovery2023，3，1： | 0 |
| 5 | Recognition of weeds at asparagus fields using multi-feature fusion and backpropagation neural network显示文摘In order to solve the problem of low recognition rates of weeds by a single feature,a method was proposed in this study to identify weeds in Asparagus(Asparagus officinalis L.)field using multi-feature fusion and backpropagation neural network(BPNN).A total of 382 images of weeds competing with asparagus growth were collected,including 135 of Cirsium arvense(L.)Scop.,138 of Conyza sumatrensis(Retz.)E.Walker,and 109 of Calystegia hederacea Wall.The grayscale images were extracted from the RGB images of weeds using the 2G-R-B factor.Threshold segmentation of the grayscale image of weeds was applied using Otsu method.Then the internal holes of the leaves were filled through the expansion and corrosion morphological operations,and other interference targets were removed to obtain the binary image.The foreground image was obtained by masking the binary image and the RGB image.Then,the color moment algorithm was used to extract weeds color feature,the gray level co-occurrence matrix and the Local Binary Pattern(LBP)algorithm was used to extract weeds texture features,and seven Hu invariant moment features and the roundness and slenderness ratio of weeds were extracted as their shape features.According to the shape,color,texture,and fusion features of the test samples,a weed identification model was built.The test results showed that the recognition rate of Cirsium arvense(L.)Scop.,Calystegia hederacea Wall.and Conyza sumatrensis(Retz.)E.Walker were 82.72%(color feature),72.41%(shape feature),86.73%(texture feature)and 93.51%(fusion feature),respectively.Therefore,this method can provide a reference for the study of weeds identification in the asparagus field. | Yafei Wang Xiaodong Zhang Guoxin Ma Xiaoxue Du Naila Shaheen Hanping Mao | 2021 | International Journal of Agricultural and Biological Engineering2021，14，4： | 0 |
| 6 | Ensemble learning system to identify nutritional risk and malnutrition in cancer patients without weight loss information显示文摘Dear Editor,Malnutrition is a prevalent disease in oncology practice(Arends et al.,2017).With its cancer-specific prevalence ranging from 21%–72%,malnutrition is responsible for 10%–20% cancer deaths(Yin et al.,2021b).However,malnutrition is often underestimated,misclassified,or left untreated in cancer care(Hébuterne et al.,2014). | Liangyu Yin Jie Liu Ming Liu Jin Zheng Aiguo Xu Quanjun Lyu Yongdong Feng Zengqing Guo Hu Ma Jipeng Li Zhikang Chen Hui Wang Zengning Li Chunling Zhou Xi Gao Min Weng Qinghua Yao Wei Li Tao Li Hanping Shi Hongxia Xu | 2023 | Science China(Life Sciences)2023，66，5： | 0 |
| 7 | Highly sensitive detection of daminozide using terahertz metamaterial sensors显示文摘In order to solve the problems of low sensitivity and complex sample pretreatment in traditional detection,a method was proposed in this study to detect daminozide using terahertz combined with a metamaterial sensor,which enables real-time and label-free molecular detection with high sensitivity.The correlation between the transmission frequency shift and absorbance of daminozide solution at different concentrations was analyzed.The simulation and experimental results showed that this metamaterial sensor could achieve highly sensitive sensing of daminozide solutions at 0.05 mg/L.The maximum quality factor(Q_(max))of the two peaks could reach 5.78 and 13.05,and the maximum figure of merit(FOM)of the two peaks can reach 0.82 and 1.72.The maximum sensitivity of two resonance peaks reached 38.148 GHz/(mg·L)and 133.516 GHz/(mg·L)when the concentration of daminozide in the solution was 2000 mg/L.There was an obvious positive correlation between the transmission and transmission,frequency shift and frequency shift,and absorbance and absorbance of the resonance peak of daminozide solutions.Therefore,this platform not only opens up new possibilities for the microanalysis of the chemical composition of substances in solutions but also provides a valuable reference for the design of other metamaterial-based sensors in the field of food safety. | Hanping Mao Xiaoxue Du Yuting Yan Xiaodong Zhang Guoxin Ma Yafei Wang Yong Liu Bin Wang Xiaoyue Yang Qiang Shi | 2022 | International Journal of Agricultural and Biological Engineering2022，15，6： | 0 |
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