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| 1 | A High-Density SNP Genotyping Array for Rice Biology and Molecular Breeding显示文摘一个高密度的单个核苷酸多型性(SNP ) 数组为遗传学者和分子的 breeders.With 是极其重要的 genomic 的巨大的数量的累积重新定序为精确 SNP 察觉的数据和可得到的技术,设计高密度、高质量的米饭 SNP 数组是可能的。这里,我们报导一个高密度的 riceSNP 数组和它的实用程序的开发。SNP 探针被屏蔽超过 10 设计从变化和一个数组说出 RiceSNP50 的 801 米饭的 re-sequencingdata 提取的 000 000 SNP loci 在 Illumina Infinium 站台上被生产。数组 contained51 478 个均匀地分布式的标记,其 68% 个在遗传因子的区域以内。有 parent/F1 relationshipswere 的几百米饭植物过去常为精确 SNP 打电话产生一个高质量的簇文件。应用程序测试证明这穿有的 highgenotyping 精确性,并且能被用于不同目的。例如,有好分辨率的精英米饭变化 wasclustered 的一个核心集合。染色体宽的协会研究(GWAS ) 分析正确地识别了描绘的 QTL.Further,这个数组成功地为变化确认和特点基因渗入被使用。作为一个精确 high-throughputgenotyping 工具, RiceSNP50 将在两功能的 genomics 学习和分子的 breeding.Key 词起一个重要作用: | Haodong Chen Weibo Xie Hang He Huihui Yu Wei Chen Jing Li Renbo Yu Yue Yao Wenhui Zhang Yuqing He Xiaoyan Tang Fasong Zhou Xing Wang Deng Qifa Zhang | 2014 | Molecular Plant2014,7,3: | 38 |
| 2 | A Possible Dynamic Mechanism for Rapid Production of the Extreme Hourly Rainfall in Zhengzhou City on 20 July 2021显示文摘In this study,the unprecedented extreme rainfall event during 19-20 July 2021,which caused devastating flooding in Zhengzhou City and its nearby areas,is examined based on observational data analysis and WRF model 40-h simulations on 1-km horizontal resolution.The results show that the model successfully reproduces(i)major synopticscale weather systems(i.e.,the western Pacific subtropical high,the Tibetan high,two typhoons,and the Huang-Huai cyclone),(ii)convective initiation along the east to north edge of the Songshan Mountain,where orographic lifting is obvious,and(iii)subsequent formation of the convective storm producing the extreme rainfall in Zhengzhou.In particular,the model generates the maximum rainfall rate of 233 mm h^(-1)and 40-h accumulated rainfall of 704 mm,corresponding well to the observed extreme values of 201.9 mm h^(-1)and 818 mm,at nearly observed timing and location.Importantly,the model reproduces an intense quasi-stationary,well-organized meso-γ-scale convective system,surrounded by an arc-shaped convergence zone,allowing the development of convective updrafts in a three-quarter circle around the convective system,in a way similar to“multidirectional pumping,”attracting all associated precipitation overlaid and concentrated into the same trailing region to generate the extreme hourly rainfall over Zhengzhou.Our study emphasizes the significant contribution of the unique dynamic structure of the well-organized meso-γ-scale convective system to the record-high hourly rainfall.A possible dynamic mechanism for short-time extreme rainfall production is proposed.That is,the arc-shaped convergence zone of the mesoscale convective system,acting like multidirectional lifting pumps,transports precipitation from different directions into the same region,and thus produces the extreme rainfall.The results gained herein may shed new light on better understanding and forecasting of short-time extreme rainfall. | Jinfang YIN Haodong GU Xudong LIANG Miao YU Jisong SUN Yanxin XIE Feng LI Chong WU | 2022 | Journal of Meteorological Research2022,36,1: | 17 |
| 3 | B-doped and La_(4)NiLiO_(8)-coated Ni-rich cathode with enhanced structural and interfacial stability for lithium-ion batteries显示文摘Ni-rich layered oxides are considered promising cathodes for advanced lithium-ion batteries(LIBs)in the future,owing to their high capacity and low cost.However,the issues on structural and interfacial stability of Ni-rich cathodes still pose substantial obstacles in the practical application of advanced LIBs.Here,we employ a one-step method to synthesize a B-doped and La_(4)NiLiO_(8)-coated LiNi_(0.82)5Co_(0.115)Mn_(0.06)O_(2)(BL-1)cathode with reliable structure and interface,for the first time.The La_(4)NiLiO_(8)coating layer can prevent cathodes from electrolyte assault and facilitate Li+diffusion kinetics.Moreover,B-doping can effectively restrain the pernicious H_(2)-H_(3) phase transition and adjust the orientation of primary particles to a radial alignment,which is obstructive to the arise of microcracks induced by the change of anisotropic volume.Specifically,when tested in pouch cells,the BL-1 cathode exhibits outstanding capacity retention of 93.49%after 500 cycles at 1 C.This dual-modification strategy dramatically enhances the stability of the structure and interface for Ni-rich cathode materials,consequently accelerating the commercialization process of high-energy–density LIBs. | Lingjun Li Lizhi Fu Miao Li Chu Wang Zixiang Zhao Shangchen Xie Haichen Lin Xianwen Wu Haodong Liu Li Zhang Qiaobao Zhang Lei Tan | 2022 | Journal of Energy Chemistry2022,31,8: | 10 |
| 4 | Effect of the graphitic degree of carbon supports on the catalytic performance of ammonia synthesis over Ba-Ru-K/HSGC catalyst显示文摘A series of high surface area graphitic carbon materials(HSGCs) were prepared by ball-milling method. Effect of the graphitic degree of HSGCs on the catalytic performance of Ba-Ru-K/HSGC-x(x is the ball-milling time in hour) catalysts was studied using ammonia synthesis as a probe reaction. The graphitic degree and pore structure of HSGC-x supports could be successfully tuned via the variation of ball-milling time. Ru nanoparticles of different Ba-Ru-K/HSGC-x catalysts are homogeneously distributed on the supports with the particle sizes ranging from 1.6 to 2.0 nm. The graphitic degree of the support is closely related to its facile electron transfer capability and so plays an important role in improving the intrinsic catalytic performance of Ba-Ru-K/HSGC-x catalyst. | Wei Jiang Ying Li Wenfeng Han Yaping Zhou Haodong Tang Huazhang Liu | 2014 | Journal of Energy Chemistry2014,23,4: | 8 |
| 5 | Ultra-broadband on-chip twisted light emitter for optical communications显示文摘On-chip twisted light emitters are essential components of orbital angular momentum(OAM)communication devices1,2.These devices address the growing demand for high-capacity communication systems by providing an additional degree of freedom for wavelength/frequency division multiplexing(WDM/FDM).Although whispering-gallery-mode-enabled OAM emitters have been shown to possess some advantages3–5,such as compactness and phase accuracy,their inherent narrow bandwidths prevent them from being compatible with WDM/FDM techniques.Here,we demonstrate an ultra-broadband multiplexed OAM emitter that utilizes a novel joint path-resonance phase control concept.The emitter has a micron-sized radius and nanometer-sized features.Coaxial OAM beams are emitted across the entire telecommunication band from 1,450 to 1,650 nm.We applied the emitter to an OAM communication with a data rate of 1.2 Tbit/s assisted by 30-channel optical frequency combs(OFCs).The emitter provides a new solution to further increase capacity in the OFC communication scenario. | Zhenwei Xie Ting Lei Fan Li Haodong Qiu Zecen Zhang Hong Wang Changjun Min Luping Du Zhaohui Li Xiaocong Yuan | 2018 | Light(Science & Applications)2018,7,1: | 7 |
| 6 | High performance columnar-like Fe2O3@carbon composite anode via yolk@shell structural design显示文摘Conversion-type reaction anode materials with high specific capacity are attractive candidates to improve lithium ion batteries(LIBs), yet the rapid capacity fading and poor rate capability caused by drastic volume change and low electronic conductivity greatly hinder their practical applications. To circumvent these issues, the successful design of yolk@shell Fe2 O3@C hybrid composed of a columnar-like Fe2O3 core within a hollow cavity completely surrounded by a thin, self-supported carbon(C) shell is presented as an anode for high-performance LIBs. This yolk@shell structure allows each Fe2O3 core to swell upon lithiation without deforming the carbon shell. This preserves the structural and electrical integrity against pulverization, as revealed by in situ transmission electron microscopy(TEM) measurement. Benefiting from these structural advantages, the resulting electrode exhibits a high reversible capacity(1013 m Ah g-1 after80 cycles at 0.2 A g-1), outstanding rate capability(710 m Ah g-1 at 8 A g-1) and superior cycling stability(800 m Ah g-1 after 300 cycles at 4 A g-1). A Li-ion full cell using prelithiated yolk@shell Fe2 O3@C hybrid as the anode and commercial Li CoO2(LCO) as the cathode demonstrates impressive cycling stability with a capacity retention of 84.5% after 100 cycles at 1 C rate, holding great promise for future practical applications. | Zhiming Zheng Pei Li Jason Huang Haodong Liu Yi Zao Zhongli Hu Li Zhang Huixin Chen Ming-Sheng Wang Dong-Liang Peng Qiaobao Zhang | 2020 | Journal of Energy Chemistry2020,29,2: | 7 |
| 7 | Pros and Cons: Autophagy in Acute Spinal Cord Injury显示文摘Autophagy plays an important role in the development and pathogenesis of various diseases. It can be induced by a variety of events such as hypoxia, nutrient-starvation, and mechanical damage. Many neurological disorders such Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, cerebral ischemia, and acute spinal cord injury (ASCI), are closely related to autophagy. However, therapeutic strategies to manipulate autophagy have not yet been fully deciphered due to the limited knowledge of the molecular mechanisms underlying autophagy in these disorders. | Zheng Li Tianshi Chen Yuanwu Cao Xiaoxing Jiang Haodong Lin Jian Zhang Zixian Chen | 2019 | Neuroscience Bulletin2019,35,5: | 6 |
| 8 | Atg5 regulates late endosome and lysosome biogenesis显示文摘Autophagy is an evolutionarily conserved lysosome-based degradation process.Atg5 plays a very important role in autophagosome formation.Here we show that Atg5 is required for biogenesis of late endosomes and lysosomes in an autophagy-independent manner.In Atg5 cells,but not in other essential autophagy genes defecting cells,recycling and retrieval of late endosomal components from hybrid organelles are impaired,causing persistent hybrid organelles and defective formation of late endosomes and lysosomes.Defective retrieval of late endosomal components from hybrid organelles resulting from impaired recruitment of a component of V1-ATPase to acidic organelles blocks the pH-dependent retrieval of late endosomal components from hybrid organelles.Lowering the intracellular pH restores late endosome/lysosome biogenesis in Atg5 cells.Our data demonstrate an unexpected role of Atg5 and shed new light on late endosome and lysosome biogenesis. | PENG JunYa ZHANG Ran CUI YiTong LIU HaoDong ZHAO XiaoXin HUANG Lei HU MingXu YUAN XiaoXi MA BenYu MA XiaoWei TAKASHI Ueno MASAAKI Komatsu LIANG XingJie YU Li | 2014 | Science China(Life Sciences)2014,57,1: | 6 |
| 9 | Flexible rechargeable Ni//Zn battery based on self-supported NiCo_2O_4 nanosheets with high power density and good cycling stability显示文摘The overall electrochemical performances of Ni-Zn batteries are still far from satisfactory, specifically for rate performance and cycling stability Herein, we demonstrated a high-performance flexible Ni//Zn battery with outstanding durability and high power density based on selfsupported NiCo_2 O_4 nanosheets as cathode and Zn nanosheets as anode. This Ni//Zn battery is able to deliver a remarkable capacity of183.1 mAh g^(-1) and a good cycling performance(82.7% capacity retention after 3500 cycles). More importantly, this battery achieves an admirable power density of 49.0 kW kg^(-1) and energy density of 303.8 Wh kg^(-1), substantially higher than most recently reported batteries. With such excellent electrochemical performance, this battery will have great potential as an ultrafast power source in practical application. | Haozhe Zhang Xinyue Zhang Haodong Li Yifeng Zhang Yinxiang Zeng Yexiang Tong Peng Zhang Xihong Lu | 2018 | Green Energy & Environment2018,3,1: | 5 |
| 10 | Screen efficiency comparisons of decision tree and neural network algorithms in machine learning assisted drug design显示文摘In view of huge search space in drug design, machine learning has become a powerful method to predict the affinity between small molecular drug and targeting protein with the development of artificial intelligence technology. However, various machine learning algorithms including massive different parameters make the prediction framework choice to be quite difficult. In this work, we took a recent drug design competition(from XtalPi company on the DataCastle platform) as the typical case to find the optimized parameters for different machines learning algorithms and the most effective algorithm. After the parameter optimizations, we compared the typical machine learning methods as decision tree(XGBoost, LightGBM) and artificial neural network(MLP, CNN) with root-mean-square error(RMSE) and coefficient of determination(R^2) evaluation. As a result, decision tree is more effective than the neural network as LightGBM>XGBoost>CNN>MLP in the affinity prediction of the specific drug design problem with ~160000 samples. For a much larger screening task in a more complicated drug design study, the sophisticated neural network model may go beyond the decision tree algorithm after generalization enhancing and overfitting reducing. The advanced machine learning methods could extract more information of protein-ligand bindings than traditional ones and improve the screen efficiency of drug design up to 200–1000 times. | Qiumei Pu Yinghao Li Hong Zhang Haodong Yao Bo Zhang Bingji Hou Lin Li Yuliang Zhao Lina Zhao | 2019 | Science China Chemistry2019,62,4: | 5 |
| 11 | Arabidopsis DET1 Represses Photomorphogenesis in Part by Negatively Regulating DELLA Protein Abundance in Darkness显示文摘DET1 否定地在黑暗中调整 DELLA 蛋白质丰富。 | Kunlun Li Zhaoxu Gao Hang He William Terzaghi Liu-Min Fan Xing Wang Deng Haodong Chen | 2015 | Molecular Plant2015,8,4: | 4 |
| 12 | Activation of peracetic acid by metal-organic frameworks(ZIF-67)for efficient degradation of sulfachloropyridazine显示文摘Peracetic acid(PAA)-based system is becoming an emerging advanced oxidation process(AOP)for effective removal of organic contaminants from water.Various approaches have been tested to activate PAA,while no previous researches reported the application of metal-organic frameworks(MOFs)materials for PAA activation.In this study,zeolitic imidazole framework(ZIF)-67,a representative MOFs,was facile synthesized via direct-mixing method at room temperature,and tested for PAA activation and sulfachloropyridazine(SCP)degradation.The as-synthesized ZIF-67 exhibited excellent performance for PAA activation and SCP degradation with 100%of SCP degraded within 3 min,owing to the specific MOFs structure and abundant Co^(2+) sites.The pseudo-first-order kinetic model was applied to fit the kinetic data,with rate constant k_(1) of ZIF-67 activated PAA system 34.2 and 156.5 times higher than those of conventional Co_(3)O_(4)activated PAA and direct oxidation by PAA.Radical quenching experiments and electron paramagnetic resonance(EPR)analysis indicated that CH_(3)C(O)OO^(·)played a major role in this PAA activation system.Then,the Fukui index based on density functional theory(DFT)calculation was used to predict the possible reaction sites of SCP for electrophilic attack by CH_(3)C(O)OO^(·).In addition,the degradation pathway of SCP was proposed based on Fukui index values and intermediates detection,which mainly included the S-N bond cleavage and SO_(2)extrusion and followed by further oxidation,dechlorination,and hydroxylation.Therefore,ZIF-67 activated PAA is a novel strategy and holds strong potential for the removal of emerging organic contaminants(EOCs)from water. | Jun Duan Long Chen Haodong Ji Peishen Li Fan Li Wen Liu | 2022 | Chinese Chemical Letters2022,33,6: | 3 |
| 13 | Image processing operations identification via convolutional neural network显示文摘Dear editor,In recent years,image forensics has attracted increasing attention,and many forensic methods have been proposed for identifying image processing operations.Until now,most existing methods have been based on hand-crafted features,and only one specific operation is considered in these methods.In many forensic scenarios,however,multiple classification for various image processing operations is more practical.In addition,for some image processing operations,it is difficult to construct effective hand-crafted features.In this study,we therefore propose a new method based on convolutional neural networks(CNNs)to adaptively learn discriminative features for identifying typical image processing operations.However,directly employ CNN structures in other fields(e.g.,computer vision)for image forensics cannot obtain satisfactory performance.Thus,we carefully design the network structures(including the highpass filter bank,the channel expansion layer,the pooling layers,and the activation functions)of the proposed method.Experimental results show that the proposed method outperforms the current best method,which is based on hand-crafted features,and three related methods based on CNNs for image steganalysis and/or forensics,achieving stateof-the-art results.Furthermore,we provide supplementary results to show the rationality and robustness of the proposed model. | Bolin CHEN Haodong LI Weiqi LUO Jiwu HUANG | 2020 | Science China(Information Sciences)2020,63,3: | 3 |
| 14 | Application of Optical Tweezers in the Research of Molecular Interaction between Lymphocyte Function Associated Antigen-1 and Its Monoclonal Antibody显示文摘Lymphocyte function associated antigen-1 (CD11a/CD18, LFA-1) plays an important role in the structure of the immunological synapse and is required for efficient lysis of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. To study the activation mode of LFA-1 on the NK cell surface, optical tweezers were used in the work. As an emerging technology, optical tweezers are widely used to manipulate microscopic objects and measure the forces of molecular interactions in the field of biological research. In our study, a new platform was constructed to study the single molecular behavior of receptor on cell surface using optical tweezers. Based on the platform, the interaction between an NK cell and a polystyrene microsphere coated with anti-LFA-1 antibody was observed. The result confirmed that the adhesion forces between an NK cell and a polystyrene bead were time-dependent. According to our findings, we propose that anti-LFA-1 antibody may cause the clustering of LFA-1 on NK cell surface. | Haodong Chen Kuikui Ge Yinmei Li Jianguang Wu Yongqiang Gu Haiming Wei Zhigang Tian | 2007 | Cellular & Molecular Immunology2007,4,3: | 3 |
| 15 | Joint resource allocation for hybrid NOMA-assisted MEC in 6G networks显示文摘Multi-access Edge Computing(MEC)is an essential technology for expanding computing power of mobile devices,which can combine the Non-Orthogonal Multiple Access(NOMA)in the power domain to multiplex signals to improve spectral efficiency.We study the integration of the MEC with the NOMA to improve the computation service for the Beyond Fifth-Generation(B5G)and the Sixth-Generation(6G)wireless networks.This paper aims to minimize the energy consumption of a hybrid NOMA-assisted MEC system.In a hybrid NOMA system,a user can offload its task during a time slot shared with another user by the NOMA,and then upload the remaining data during an exclusive time duration served by Orthogonal Multiple Access(OMA).The original energy minimization problem is non-convex.To efficiently solve it,we first assume that the user grouping is given,and focuses on the one group case.Then,a multilevel programming method is proposed to solve the non-convex problem by decomposing it into three subproblems,i.e.,power allocation,time slot scheduling,and offloading task assignment,which are solved optimally by carefully studying their convexity and monotonicity.The derived solution is optimal to the original problem by substituting the closed expressions obtained from those decomposed subproblems.Furthermore,we investigate the multi-user case,in which a close-to-optimal algorithm with lowcomplexity is proposed to form users into different groups with unique time slots.The simulation results verify the superior performance of the proposed scheme compared with some benchmarks,such as OMA and pure NOMA. | Haodong Li Fang Fang Zhiguo Ding | 2020 | Digital Communications and Networks2020,6,3: | 3 |
| 16 | Role of surface defects of carbon nanotubes on catalytic performance of barium promoted ruthenium catalyst for ammonia synthesis显示文摘Carbon nanotubes(CNTs) with abundant surface defects are prepared by a liquid oxidation and thermal annealing method. The defective CNTs-D supported Ba–Ru/CNTs-D catalysts exhibit superior catalytic performance in ammonia synthesis with a TOF be increased up to 0.30 s-1, which is 2.5 times of oxidized CNTs-O supported Ba–Ru/CNTs-O catalysts and 5 times of the Ba–Ru/CNTs. The characterizations by CO chemisorption, transmission electron microscope, Raman, and X-ray photoelectron spectroscopy revealed that the uniformly well dispersed Ru NPs can be stabilized on the defective sites of CNTs-D. The great improvement of the catalytic performance and stability of the Ba–Ru/CNTs-D is contributed to the strong interaction between Ru NPs and surface defect of the CNTs. | Yongcheng Ma Guojun Lan Wenzhao Fu Ying Lai Wenfeng Han Haodong Tang Huazhang Liu Ying Li | 2020 | Journal of Energy Chemistry2020,29,2: | 2 |
| 17 | Fractal characteristic of microscopic pore structure of tight sandstone reservoirs in Kalpintag Formation in Shuntuoguole area,Tarim Basin显示文摘Using the fractal geometry method,the microscopic pore structures of tight sandstone reservoirs in Kalpintag Formation of Shuntuoguole area in Tarim Basin were conducted fractal characterization on the base of test analysis data such as physical property,cast thin section,scanning electron microscope and mercury injection,and the genetic mechanism of pore structure heterogeneity was investigated.The storage spaces are dominated by intergranular dissolved pore,intragranular dissolved pore and residual intergranular pore,and the throat type consists of the necking throat,lamellar throat,curved lamellar throat and tube-shaped throat.The microscopic structure type includes Type Ⅰ(fractal dimension≤2.350),Type Ⅱ(2.3502.580)and fracture type.The most favorable reservoirs with Type-Ⅰ microscopic pore structure are mainly distributed in the Upper Member of Kalpintag Formation,while the reservoirs with Type-Ⅱ and Type-Ⅲ microscopic pore structures are mainly in the Lower Member of Kalpintag Formation.The sedimentation controls the heterogeneity of microscopic pore structure,and the differences on composition and particle size of sandstone lead to differentiation of microscopic pore structures.The Lower Member of the Kalpintag Formation experiences stronger compaction and cementation but weaker dissolution than the Upper Member of the Kalpingtag Formation,and thus the microscopic pore structure of Upper Member of the Kalpintag Formation is significantly worse that of the Lower Member o the Kalpingtag Formation.The Upper Member of the Kalpintag Formation with high content of brittle mineral develops microscopic fractures due to tectonic rupture,thus the permeability is improved and the heterogeneity of microscopic pore structures is enhanced;but the Lower Member of Kalpintag Formation is characterized by attrition crushing of particles and strong compaction. | Jun Peng Haodong Han Qingsong Xia Bin Li | 2020 | Petroleum Research2020,5,1: | 2 |
| 18 | Reliability and global sensitivity analysis for an airplane slat mechanism considering wear degradation显示文摘This paper focuses on the issue of reliability and global sensitivity analysis for an airplane slat mechanism considering the uncertainties in the wear process of mechanical components.First,the multi-body kinematic model of the slat mechanism is built in the ADAMS software.The geometrical sizes of the roller wheels after wear degradation are considered as input variables and the angle the slat should turn is considered as the output response.To accurately identify the influential roller wheels to the reliability and robustness of the slat mechanism,the failure probability based sensitivity and variance-based sensitivity indices are introduced.Comprehensive analysis of the results have shown that the reliability analysis and global sensitivity theory can help engineers find significant parts by their contributions,thus provide guidance for mechanical design and maintenance. | Changcong ZHOU Haodong ZHAO Qi CHANG Mengyao JI Chen LI | 2021 | Chinese Journal of Aeronautics2021,34,1: | 2 |
| 19 | In-situ transient photovoltage study on interface electron transfer regulation of carbon dots/NiCo_(2)O_(4) photocatalyst for the enhanced overall water splitting activity显示文摘Photocatalytic hydrogen production by overall water solar-splitting is a prospective strategy to solve energy crisis.However,the rapid recombination of photogenerated electron–hole pairs deeply restricts photocatalytic activity of catalysts.Here,the in-situ transient photovoltage(TPV)technique was developed to investigate the interfacial photogenerated carrier extraction,photogenerated carrier recombination and the interfacial electron delivery kinetics of the photocatalyst.The carbon dots/NiCo_(2)O_(4)(CDs/NiCo_(2)O_(4))composite shows weakened recombination rate of photogenerated carriers due to charge storage of CDs,which enhances the photocatalytic water decomposition activity without any scavenger.CDs can accelerate the interface electron extraction about 0.09 ms,while the maximum electron storage time by CDs is up to 0.7 ms.The optimal CDs/NiCo_(2)O_(4)composite(5 wt.%CDs)displays the hydrogen production of 62µmol·h^(−1)·g^(−1) and oxygen production of 29µmol·h^(−1)·g^(−1) at normal atmosphere,which is about 4 times greater than that of pristine NiCo_(2)O_(4).This work provides sufficient evidence on the charge storage of CDs and the interfacial charge kinetics of photocatalysts on the basis of in-situ TPV tests. | Haodong Nie Yan Liu Yi Li Kaiqiang Wei Zhenyu Wu Hong Shi Hui Huang Yang Liu Mingwang Shao Zhenhui Kang | 2022 | Nano Research2022,15,3: | 2 |
| 20 | Global antimicrobial resistance:a system-wide comprehensive investigation using the Global One Health Index显示文摘Background:Antimicrobial resistance(AMR)is one of the top ten global public health challenges.However,given the lack of a comprehensive assessment of worldwide AMR status,our objective is to develop a One Health-based system-wide evaluation tool on global AMR.Methods:We have further developed the three-hierarchical Global One Health Index(GOHI)-AMR indicator scheme,which consists of five key indicators,17 indicators,and 49 sub-indicators,by incorporating 146 countries'data from diverse authoritative databases,including WHO's Global Antimicrobial Resistance and Use Surveillance System(GLASS)and the European CDC.We investigated the overall-or sub-rankings of GOHI-AMR at the international/regional/national levels for data preprocessing and score calculation utilizing the existing GOHI methodology.Additionally,a correlation analysis was conducted between the GOHI-AMR and other socioeconomic factors.Results:The average GOHI-AMR score for 146 countries is 38.45.As expected,high-income countries(HICs)outperform the other three income groups on overall rankings and all five key indicators of GOHI-AMR,whereas lowincome countries unexpectedly outperform upper-middle-income countries and lower-middle-income countries on the antibiotics-resistant key indicator(ARR)and ARR-subordinate indicators,including carbapenem-,β-lactam-,and quinolone resistance,and even HICs on aminoglycoside resistance.There were no significant differences among the four groups on the environmental-monitoring indicator(P>0.05).GOHI-AMR was positively correlated with gross domestic product,life expectancy,and AMR-related publications,but negatively with natural growth rate and chronic respiratory disease.In contrast to Cyprus,the remarkably lower prevalence of'ESKAPE pathogens'in high-scoring Sweden and Denmark highlights Europe's huge gaps.China and Russia outperformed the other three BRICS countries on all key indicators,particularly India's ARR and Brazil's AMR laboratory network and coordination capacity.Furthermore,significant internal disparities in carbapenem-resistant Klebsiella pneumoniae(CRKP)and methicillin-resistant Staphylococcus aureus(MRSA)prevalence were observed between China and the USA,with MRSA prevalence both gradually declining,whereas CRKP prevalence has been declining in the USA but increasing in China,consistent with higher carbapenems-related indicator'performance in USA.Conclusions:GOHI-AMR is the most comprehensive tool currently available for the assessment of AMR status worldwide.We discovered unique features impacting AMR in each country and offered precise recommendations to improve the capacity to tackle AMR in low-ranking countries. | Nan Zhou Zile Cheng Xiaoxi Zhang Chao Lv Chaoyi Guo Haodong Liu Ke Dong Yan Zhang Chang Liu Yunfu Chang Sheng Chen Xiaokui Guo Xiao-Nong Zhou Min Li Yongzhang Zhu | 2022 | Infectious Diseases of Poverty2022,11,4: | 2 |