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| 1 | Trustworthy Mobile Network Architecture Based on Locator/Identity Split显示文摘 | Haoxue Wang Ke Zhu Yuxiang Hu Dongnian Cheng | 2008 | Journal of Systems Science and Information2008,6,1: | 0 |
| 2 | Flexible Diodes/Transistors Based on Tunable p-n-Type Semiconductivity in Graphene/Mn-Co-Ni-O Nanocomposites显示文摘We report a novel Mn-Co-Ni-O(MCN)nanocomposite in which the p-type semiconductivity of Mn-Co-Ni-O can be manipulated by addition of graphene.With an increase of graphene content,the semiconductivity of the nanocomposite can be tuned from p-type through electrically neutral to n-type.The very low effective mass of electrons in graphene facilitates electron tunneling into the MCN,neutralizing holes in the MCN nanoparticles.XPS analysis shows that the multivalent manganese ions in the MCN nanoparticles are chemically reduced by the graphene electrons to lower-valent states.Unlike traditional semiconductor devices,electrons are excited from the filled graphite band into the empty band at the Dirac points from where they move freely in the graphene and tunnel into the MCN.The new composite film demonstrates inherent flexibility,high mobility,short carrier lifetime,and high carrier concentration.This work is useful not only in manufacturing flexible transistors,FETs,and thermosensitive and thermoelectric devices with unique properties but also in providing a new method for future development of 2D-based semiconductors. | Lihong Su Zhou Yang Xitong Wang Ziao Zou Bo Wang Gary Hodes Ninghui Chang Yongyong Suo Zhibo Ma Haoxu Wang Yucheng Liu Junping Zhang Shuanhu Wang Yuefei Li Fengxia Yang Jixin Zhu Fei Gao Wei Huang Shengzhong Liu | 2022 | Research2022,,1: | 0 |
| 3 | Whole-milk consumption decreases the risk of inflammatory bowel disease:a two-sample Mendelian rand omization analysis显示文摘Objective: The impact of dairy fat on inflammatory bowel disease remained inconclusive. We aimed to compare the effects of whole-milk and skimmed-milk consumption on the risk of inflammatory bowel disease using a Mendelian randomization analysis.Methods: We conducted a genome-wide association study of the preference for whole versus skimmed milk using data for 20,200 whole-milk consumers and 67,847 skimmed-milk consumers from the UK Biobank. The lead single nucleotide polymorphisms in the associated loci were identified at the genome-wide significance level, and were further employed as instrumental variables for whole-milk preference. We conducted a two-sample Mendelian randomization analysis with whole-milk preference as the exposure and inflammatory bowel disease as the outcome. The pleiotropic effects and heterogeneity of the instrumental variables were estimated using Mendelian randomization-Egger regression and CochranQ test, respectively. This study was conducted using the UKB resources under the application '53536' . The UK Biobank was approved by the North West Multi-center Research Ethics Committee, the National Information Governance Board for Health and Social Care in England and Wales, and the Community Health Index Advisory Group in Scotland.Results: The genome-wide association study identified five lead nucleotide polymorphisms associated with whole-milk preference. Mendelian randomization indicated that whole-milk preference significantly decreased the risk of inflammatory bowel disease (β=-1.735,P=0.048). Of the two subtypes, whole-milk preference was associated with a lower risk of Crohn disease (β=-2.549,P=0.032), but had no significant effect on the risk of ulcerative colitis (β=-1.002,P=0.44).Conclusion: Consumption of whole-milk fat may protect against Crohn disease, compared with skimmed milk. This conclusion was based on causal inference in a cohort study, and further validation in randomized controlled trials is warranted. | Jiuling Li Haoxue Zhu Aowen Tian Ying Guo Xiaoxuan Zhao Miaoran Zhang Lanlan Chen Jianping Wen Jianli Yang Baiyu Qi Peng Chen | 2021 | Journal of Bio-X Research2021,4,3: | 0 |
| 4 | A Centralized Algorithm for Assigning MDC Video Application in Virtual Network显示文摘Providing services on demand is a major contributing factor to drive the increasingly development of the software defined network. However, it should supply all the current popular applications before it really attains widespread development. Multiple Description Coding(MDC) video applications, as a popular application in the current network, should be reasonably supported in this novel network virtualization environment. In this paper, we address this issue to assign MDC video application into virtual networks with an efficient centralized algorithm(CAMDV). Since this problem is an NP-hard problem, we design an algorithm that can effectively balance the user satisfaction and network resource cost. Previous work just builds a global multicast tree for each description to connect all the destination nodes by breadth-first search strategy or shortest path tree algorithm. But those methods could not achieve an optimal balance or a high-level user satisfaction. By introducing the hierarchical clustering scheme, our algorithm decomposes the whole mapping procedure into multicast tree construction and multipath description distribution. A serial of simulation experiments show that our centralized algorithm could achieve a better performance in balancing the user satisfaction and average mapping cost in comparison with its rivals. | ZHU Kai WU Chunming ZHOU Boyang CHEN Fei WANG Haoxue | 2016 | China Communications2016,13,S1: | 0 |
| 5 | Status of the Science and Technology Award of the Chinese Nursing Association and analysis of the development trend of nursing research显示文摘Aims and objective:This study focuses on the status quo and development trend of nursing research in our country to provide a reference for nursing research workers and improve the development of nursing research in China.Methods:The official website of the Chinese Nursing Association was searched to obtain the total number,category,geographical distribution,and job of project leaders of winning projects of the Chinese Nursing Association Technology Award.Findings were analyzed using webometrics and content analysis approach to understand the“study hotspots,”“study level,”and“development trend”of nursing research in China.Results:The total number of winning projects was 144.Among them,the number of first,second,and third prizes were 8,36,and 100,respectively.Beijing is the area with the largest number of winners(21),followed by Shanghai(17)and Jiangsu(13).Among the winning projects,the top 3 research areas were specialty nursing,nursing management,and nursing education,with percentages of 50%,27%,and 18%,respectively.Among the 144 project leaders,96% were academic or hospital directors and only 4% were ordinary staff.Conclusions:The geographical distribution of winning projects presented a regional concentration trend.The categories of winning projects are diverse,and our country has made great achievements in every category,particularly in specialty nursing.Most of the project leaders were academic or hospital directors.The stumbling block to nursing research is the lack of high-quality research projects with international influence.Future research should learn from the experiences of developed countries,focus on the in-depth refinement of specialty nursing,and highlight the importance of collaboration to coordinate and promote nursing development in all regions. | Binghan Wang Qiaoyuan Yan Qin Zhu Na Zeng Ziwa Yu Haoxue Wang | 2016 | International Journal of Nursing Sciences2016,3,3: | 0 |
| 6 | Systematic analysis on expression quantitative trait loci identifies a novel regulatory variant in ring finger and WD repeat domain 3 associated with prognosis of pancreatic cancer显示文摘Background:Pancreatic adenocarcinoma(PAAD)is an extremely lethal malignancy.Identification of the functional genes and genetic variants related to PAAD prognosis is important and challenging.Previously identified prognostic genes from several expression profile analyses were inconsistent.The regulatory genetic variants that affect PAAD prognosis were largely unknown.Methods:Firstly,a meta-analysis was performed with seven published datasets to systematically explore the candidate prognostic genes for PAAD.Next,to identify the regulatory variants for those candidate genes,expression quantitative trait loci analysis was implemented with PAAD data resources from The Cancer Genome Atlas.Then,a two-stage association study in a total of 893 PAAD patients was conducted to interrogate the regulatory variants and find the prognostic locus.Finally,a series of biochemical experiments and phenotype assays were carried out to demonstrate the biological function of variation and genes in PAAD progression process.Results:A total of 128 genes were identified associated with the PAAD prognosis in the meta-analysis.Fourteen regulatory loci in 12 of the 128 genes were discovered,among which,only rs4887783,the functional variant in the promoter of Ring Finger and WD Repeat Domain 3(RFWD3),presented significant association with PAAD prognosis in both stages of the population study.Dualluciferase reporter and electrophoretic mobility shift assays demonstrated that rs4887783-G allele,which predicts the worse prognosis,enhanced the binding of transcript factor REST,thus elevating RFWD3 expression.Further phenotypic assays revealed that excess expression of RFWD3 promoted tumor cell migration without affecting their proliferation rate.RFWD3 was highly expressed in PAAD and might orchestrate the genes in the DNA repair process.Conclusions:RFWD3 and its regulatory variant are novel genetic factors for PAAD prognosis. | Ying Zhu Xiating Peng Xiaoyang Wang Pingting Ying Haoxue Wang Bin Li Yue Li Ming Zhang Yimin Cai Zequn Lu Siyuan Niu Nan Yang Rong Zhong Jianbo Tian Jiang Chang Xiaoping Miao | 2022 | Chinese Medical Journal2022,,11: | 0 |
| 7 | Parameters Calibration of the GISSMO Failure Model for SUS301L-MT显示文摘With the development of the rail transit industry,more attention has been paid to the passive safety of rail vehicles.Structural damage is one of the main failure behaviors in a rail vehicle collision,but it has been paid little attention to in past research.In this paper,the quasi-static fracture experiments of SUS301L-MT under different stress states were carried out.The mechanical fracture properties of this material were studied,and the corresponding finite element simulation accuracy was improved to guide the design of vehicle crashworthiness.Through the tests,the fracture behavior of materials with wide stress triaxiality was obtained,and each specimen’s fracture locations and fracture strains were determined.Parameters of a generalized incremental stress state dependent damage model(GISSMO)of the material were calibrated,and the model’s accuracy was verified with test results from a 45°shear specimen.The GISSMO failure model accurately reflected the fracture characteristics of the material.The mesh dependency of this model was modified and discussed.The results show that the simulation agrees well with experimental data for the force-displacement curve after correction,but the strain distribution needs to be further studied and improved. | Tao Zhu Haoxu Ding Chao Wang Yuxin Liu Shoune Xiao Guangwu Yang Bing Yang | 2023 | Chinese Journal of Mechanical Engineering2023,36,1: | 0 |
| 8 | Flexible Diodes/Transistors Based on Tunable p-n-Type Semiconductivity in Graphene/Mn-Co-Ni-O Nanocomposites显示文摘We report a novel Mn-Co-Ni-O(MCN)nanocomposite in which the p-type semiconductivity of Mn-Co-Ni-O can be manipulated by addition of graphene.With an increase of graphene content,the semiconductivity of the nanocomposite can be tuned from p-type through electrically neutral to n-type.The very low effective mass of electrons in graphene facilitates electron tunneling into the MCN,neutralizing holes in the MCN nanoparticles.XPS analysis shows that the multivalent manganese ions in the MCN nanoparticles are chemically reduced by the graphene electrons to lower-valent states.Unlike traditional semiconductor devices,electrons are excited from the filled graphite band into the empty band at the Dirac points from where they move freely in the graphene and tunnel into the MCN.The new composite film demonstrates inherent flexibility,high mobility,short carrier lifetime,and high carrier concentration.This work is useful not only in manufacturing flexible transistors,FETs,and thermosensitive and thermoelectric devices with unique properties but also in providing a new method for future development of 2D-based semiconductors. | Lihong Su Zhou Yang Xitong Wang Ziao Zou Bo Wang Gary Hodes Ninghui Chang Yongyong Suo Zhibo Ma Haoxu Wang Yucheng Liu Junping Zhang Shuanhu Wang Yuefei Li Fengxia Yang Jixin Zhu Fei Gao Wei Huang Shengzhong Liu | 2021 | Research2021,,1: | 0 |