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| 1 | The Global Boundary Stratotype Section and Point (GSSP) for the base of the Hirnantian Stage (the uppermost of the Ordovician System)显示文摘 | Xu Chen Jiayu Rong Junxuan Fan Renbin Zhan Charles E. Mitchell David A. T. Harper Michael J. Melchin Ping'an Peng Stan C. Finney Xiaofeng Wang | 2006 | Episodes2006，29，3： | 61 |
| 2 | Successful surgical management of ruptured umbilical hernias in cirrhotic patients显示文摘Acute umbilical hernia rupture in patients with hepatic cirrhosis and ascites is an unusual,but potentially lifethreatening complication,with postoperative morbidity about 70% and mortality between 60%-80% after supportive care and 6%-20% after urgent surgical repair.Management options include primary surgical repair with or without concomitant portal venous system decompression for the control of the ascites.We present a retrospective analysis of our centre's experience over the last 6 years.Our cohort consisted of 11 consecutive patients(median age:53 years,range:36-63 years) with advanced hepatic cirrhosis and refractory ascites.Appropriate patient resuscitation and optimisation with intravenous fluids,prophylactic antibiotics and local measures was instituted.One failed attempt for conservative management was followed by a successful primary repair.In all cases,with one exception,a primary repair with non-absorbable Nylon,interrupted sutures,without mesh,was performed.The perioperative complication rate was 25% and the recurrence rate 8.3%.No mortality was recorded.Median length of hospital stay was 14 d(range:4-31 d).Based on our experience,the management of ruptured umbilical hernias in patients with advanced hepatic cirrhosis and refractory ascites is feasible without the use of transjugular intrahepatic portosystemic shunt routinely in the preoperative period,provided that meticulous patient optimisation is performed. | Nikolaos A Chatzizacharias J Andrew Bradley Simon Harper Andrew Butler Asif Jah Emmanuel Huguet Raaj K Praseedom Michael Allison Paul Gibbs | 2015 | World Journal of Gastroenterology2015，21，10： | 4 |
| 3 | Liver regeneration biology:Implications for liver tumour therapies显示文摘The liver has remarkable regenerative potential,with the capacity to regenerate after 75%hepatectomy in humans and up to 90%hepatectomy in some rodent models,enabling it to meet the challenge of diverse injury types,including physical trauma,infection,inflammatory processes,direct toxicity,and immunological insults.Current understanding of liver regeneration is based largely on animal research,historically in large animals,and more recently in rodents and zebrafish,which provide powerful genetic manipulation experimental tools.Whilst immensely valuable,these models have limitations in extrapolation to the human situation.In vitro models have evolved from 2-dimensional culture to complex 3 dimensional organoids,but also have shortcomings in replicating the complex hepatic micro-anatomical and physiological milieu.The process of liver regeneration is only partially understood and characterized by layers of complexity.Liver regeneration is triggered and controlled by a multitude of mitogens acting in autocrine,paracrine,and endocrine ways,with much redundancy and cross-talk between biochemical pathways.The regenerative response is variable,involving both hypertrophy and true proliferative hyperplasia,which is itself variable,including both cellular phenotypic fidelity and cellular trans-differentiation,according to the type of injury.Complex interactions occur between parenchymal and non-parenchymal cells,and regeneration is affected by the status of the liver parenchyma,with differences between healthy and diseased liver.Finally,the process of termination of liver regeneration is even less well understood than its triggers.The complexity of liver regeneration biology combined with limited understanding has restricted specific clinical interventions to enhance liver regeneration.Moreover,manipulating the fundamental biochemical pathways involved would require cautious assessment,for fear of unintended consequences.Nevertheless,current knowledge provides guiding principles for strategies to optimise liver regeneration potential. | Christopher Hadjittofi Michael Feretis Jack Martin Simon Harper Emmanuel Huguet | 2021 | World Journal of Clinical Oncology2021，12，12： | 2 |
| 4 | A heptosyltransferase mutant of Pasteurella multocida produces a tuuncated lipopolysaccharide structure and is attenuated in virulence显示文摘 | Cox A D St Michael F | 2004 | Infection and Immunity2004，72，： | 1 |
| 5 | Disaster tolerant systems engineering for critical infrastructure protection 显示文摘 | Harper Michael Thornton Mitchell Szygenda Stephen | 2007 | Systems Conference 1st Annual IEEE2007，9，13： | 1 |
| 6 | The MFMU Cesarean Registry: Factors affecting the success of trial of labor after previous cesarean delivery显示文摘 | Mark B. Landon Sharon Leindecker Catherine Y. Spong John C. Hauth Steven Bloom Michael W. Varner Atef H. Moawad Steve N. Caritis Margaret Harper Ronald J. Wapner Yoram Sorokin Menachem Miodovnik Marshall Carpenter Alan M. Peaceman Mary Jo O’Sullivan Baha | 2005 | American Journal of Obstetrics and Gynecology2005，，3： | 1 |
| 7 | Second-stage labor duration in nulliparous women: relationship to maternal and perinatal outcomes显示文摘 | Dwight J. Rouse Steven J. Weiner Steven L. Bloom Michael W. Varner Catherine Y. Spong Susan M. Ramin Steve N. Caritis Alan M. Peaceman Yoram Sorokin Anthony Sciscione Marshall W. Carpenter Brian M. Mercer John M. Thorp Fergal D. Malone Margaret Harper Jay | 2009 | American Journal of Obstetrics and Gynecology2009，，4： | 1 |
| 8 | Identification of novel glycosyltransferases required for assembly of the Pasteurella multocida A: 1 lipopolysaccharide and their involvement in virulence 显示文摘 | Boyce J D Harper M St Michael F | 2009 | Infec Immu2009，77，4： | 1 |
| 9 | Interaction between coupling agent and lubricants in wood-polypropylene composites显示文摘 | David Harper Michael Wolcott | | 0，，： | 1 |
| 10 | Urgent Surgical Decompression Compared to Methylprednisolone for the Treatment of Acute Spinal Cord Injury: A Randomized Prospective Study in Beagle Dogs显示文摘 | Richard S. Rabinowitz Jason C. Eck C Michel Harper Dirk R. Larson Miguel A. Jimenez Joseph E. Parisi Jonathan A. Friedman Michael J. Yaszemski Bradford L. Currier | 2008 | Spine2008，，21： | 1 |
| 11 | Risk Factors for Renal Cell Carcinoma in the Vitamin and Lifestyle (VITAL) Study显示文摘 | Liam C. Macleod James M. Hotaling Jonathan L. Wright Michael T. Davenport John L. Gore Jonathan Harper Emily White | 2013 | The Journal of Urology2013，，： | 1 |
| 12 | Kinetics of metal exchange between solids and solutions in sediments and soils interpreted from DGT measured fluxes显示文摘 | Michael P Harper William Davison Hao Zhang Wlodek Tych | 1998 | Geochimica et Cosmochimica Acta1998，，16： | 1 |
| 13 | Lipoprotein predictors of the severity of coronary artery disease in men and women显示文摘 | MICHAEL F. REARDON PAUL J. NESTEL IAN H. CRAIG RICHARD W. HARPER | 1985 | Circulation1985，，5： | 1 |
| 14 | FAIR: A Call to Make Published Data More Findable, Accessible, Interoperable, and Reusable显示文摘 | Leonore Reiser Lisa Harper Michael Freeling Bin Han Sheng Luan | 2018 | Molecular Plant2018，11，9： | 1 |
| 15 | Decora- tion of Pasteurella multocida lipopolysaccharide with phosphocholine is important for virulence显示文摘 | HARPER M COX A MICHAEL F S | 2007 | J Bac- teriol2007，189，20： | 1 |
| 16 | Role for Ferredoxin:NAD(P)H Oxidoreductase (FprA) in Sulfate Assimilation and Siderophore Biosynthesis in Pseudomonads显示文摘 | Thomas A. Lewis Angela Glassing Justin Harper Michael J. Franklin | 2013 | Journal of Bacteriology2013，，17： | 1 |
| 17 | Essentials of Ecology 显示文摘 | Colin R Townsend John L Harper Michael Begon | 2000 | Blackwell Science2000，，： | 1 |
| 18 | Natu- ral selection in the chicken host identifies 3-deoxy-I> manno-octulosonic acid kinase residues essential for phosphorylation of Pasteurella multocida lipopo- lysaccharide显示文摘 | HARPER M COX A D MICHAEL F S | 2010 | Infect Immun2010，78，9： | 1 |
| 19 | Structural and genetic basis for the serological differ- entiation of Pasteurella multocida Heddleston sero- types 2 and 5显示文摘 | MICHAEL F S HARPER M PARNAS H | 2009 | J Bacteriol2009，191，22： | 1 |
| 20 | Pas- teurella multocida Heddleston serovars 1 and 14 ex- press different lipopolysaccharide structures but share the same lipopolysaceharide biosynthesis outer core locus显示文摘 | HARPER M MICHAEL F S JOHN M | 2011 | Vet Microbiol2011，150，3： | 1 |
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